Protective action of nipradilol mediated through S-nitrosylation of Keap1 and HO-1 induction in retinal ganglion cells

Neurochemistry International

Volumn 61, Issue 7, 2012, Pages 1242-1253

  Koriyama, Yoshiki ^a   Kamiya, Marie ^a   Takadera, Tsuneo ^b   Arai, Kunizo ^a   Sugitani, Kayo ^a   Ogai, Kazuhiro ^a   Kato, Satoru ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b HOKURIKU UNIVERSITY   (Japan)

Author keywords

HO 1; Keap1; Nitric oxide; Oxidative stress; Retinal ganglion cell; S nitrosylation

Indexed keywords

4 HYDROXYNONENAL; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NIPRADILOL; PRAZOSIN; TIMOLOL; TRANSCRIPTION FACTOR NRF2;

ARTICLE; BINDING KINETICS; BIOACCUMULATION; CELL DEATH; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; NEUROPROTECTION; NITROSYLATION; OPTIC NERVE INJURY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA GANGLION CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CYTOSKELETAL PROTEINS; DNA PRIMERS; ENZYME INDUCTION; HEME OXYGENASE-1; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; POLYMERASE CHAIN REACTION; PROPANOLAMINES; RETINAL GANGLION CELLS; VASODILATOR AGENTS;

EID: 84870058778     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.09.004     Document Type: Article

References (45)

1. T. Adachi, S. Hori, K. Miyazaki, E. Takahashi, M. Nakagawa, A. Udagawa, N. Hayashi, N. Aikawa, and S. Ogawa Rapid increase in plasma nitrite concentration following intravenous administration of nipradilol Eur. J. Pharmacol. 286 1995 201 204
2. J. Alam, and J.L. Cook Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway Curr. Pharm. Des. 9 2003 2499 2511
3. A. Ando, Y. Yamazaki, S. Kaneko, M. Miyake, R. Nambu, M. Taomoto, S. Unezaki, E. Okuda-Ashitaka, T. Okumura, S. Ito, and M. Matsumura Cytoprotection by nipradilol, an anti-glaucomatous agent, via down-regulation of apoptosis related gene expression and activation of NF-kappaB Exp. Eye Res. 80 2005 501 507
4. T. Andoh, P.B. Chock, and C.C. Chiueh Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expression Ann. N. Y. Acad. Sci. 962 2002 1 7
5. B.J. Buckley, Z.M. Marshall, and A.R. Whorton Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium Biochem. Biophys. Res. Commun. 307 2003 973 979
6. B.J. Buckley, S. Li, and A.R. Whorton Keap1 modification and nuclear accumulation in response to S-nitrosocysteine Free Radic. Biol. Med. 44 2008 692 698
7. V. Castagné, and P.G. Clarke Axotomy-induced retinal ganglion cell death in development: its time-course and its diminution by antioxidants Proc. Biol. Sci. 263 1996 1193 1197
8. C.C. Chiueh Neuroprotective properties of nitric oxide Ann. N. Y. Acad. Sci. 890 1999 301 311
9. V.L. Dawson, T.M. Dawson, E.D. London, D.S. Bredt, and S.H. Snyder Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures Proc. Natl. Acad. Sci. USA 88 1991 6368 6371
10. K. Deguchi, T. Hayashi, S. Nagotani, Y. Sehara, H. Zhang, A. Tsuchiya, Y. Ohta, K. Tomiyama, N. Morimoto, M. Miyazaki, N.H. Huh, A. Nakao, T. Kamiya, and K. Abe Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress Brain Res. 1188 2008 1 8
11. J. Gao, K. Kashfi, X. Liu, and B. Rigas NO-donating aspirin induces phase II enzymes in vitro and in vivo Carcinogenesis 27 2006 803 810
12. K. Homma, Y. Koriyama, K. Mawatari, Y. Higuchi, J. Kosaka, and S. Kato Early downregulation of IGF-I decides the fate of rat retinal ganglion cells after optic nerve injury Neurochem. Int. 50 2007 741 748
13. S.Y. Hung, H.C. Liou, and W.M. Fu The mechanism of heme oxygenase-1 action involved in the enhancement of neurotrophic factor expression Neuropharmacology 58 2010 321 329
14. N. Imai, Y. Tsuyama, K. Murayama, and E. Adachi-Usami Protective effect of nitric oxide on ischemic retina Nihon Ganka Gakkai Zasshi 101 1997 639 643
15. S.R. Jaffrey, H. Erdjument-Bromage, C.D. Ferris, P. Tempst, and S.H. Snyder Protein S-nitrosylation: a physiological signal for neuronal nitric oxide Nat. Cell Biol. 3 2001 193 197
16. J.W. Kaspar, S.K. Niture, and A.K. Jaiswal Nrf2:INrf2 Keap1 signaling in oxidative stress Free Radic. Biol. Med. 47 2009 1304 1309
17. K. Kawashima, T.X. Watanabe, and H. Sokabe Pharmacodynamic and pharmacokinetic studies on prizidilol and nipradilol K-351, antihypertensive drugs with combined vasodilator and beta-adrenoceptor blocking actions, in rabbits Jpn. J. Pharmacol. 36 1984 519 526
18. Y. Kitaoka, T. Kumai, K. Isenoumi, S. Kobayashi, and S. Ueno Nipradilol induces vasodilation of canine isolated posterior ciliary artery via stimulation of the guanylyl cyclase-cGMP pathway Life Sci. 71 2002 1115 1124
19. Y. Koriyama, K. Chiba, and T. Mohri Propentofylline protects beta-amyloid protein-induced apoptosis in cultured rat hippocampal neurons Eur. J. Pharmacol. 458 2003 235 241
20. Y. Koriyama, H. Tanii, M. Ohno, T. Kimura, and S. Kato A novel neuroprotective role of a small peptide from flesh fly, 5-S-GAD in the rat retina in vivo Brain Res. 1240 2008 196 203
21. Y. Koriyama, R. Yasuda, K. Homma, K. Mawatari, M. Nagashima, K. Sugitani, T. Matsukawa, and S. Kato Nitric oxide-cGMP signaling regulates axonal elongation during optic nerve regeneration in the goldfish in vitro and in vivo J. Neurochem. 110 2009 890 901
22. Y. Koriyama, M. Ohno, T. Kimura, and S. Kato Neuroprotective effects of 5-S-GAD against oxidative stress-induced apoptosis in RGC-5 cells Brain Res. 1296 2009 187 195
23. K. Kou, J. Ibengwe, and H. Suzuki Effects of alpha-adrenoceptor antagonists on electrical and mechanical responses of the isolated dog mesenteric vein to perivascular nerve stimulation and exogenous noradrenaline Naunyn Schmiedeberg's Arch. Pharmacol. 326 1984 7 13
24. R.R. Krishnamoorthy, P. Agarwal, G. Prasanna, K. Vopat, W. Lambert, H.J. Sheedlo, I.H. Pang, D. Shade, R.J. Wordinger, T. Yorio, A.F. Clark, and N. Agarwal Characterization of a transformed rat retinal ganglion cell line Brain Res. Mol. Brain Res. 86 2001 1 12
25. Y. Kurauchi, A. Hisatsune, Y. Isohama, and H. Katsuki Nitric oxide-cyclic GMP signaling pathway limits inflammatory degeneration of midbrain dopaminergic neurons: cell type-specific regulation of heme oxygenase-1 expression Neuroscience 158 2009 856 866
26. H. Levkovitch-Verbin, C. Harris-Cerruti, Y. Groner, L.A. Wheeler, M. Schwartz, and E. Yoles RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotection Invest. Ophthalmol. Vis. Sci. 41 2000 4169 4174
27. C.Q. Li, M.Y. Kim, L.C. Godoy, A. Thiantanawat, L.J. Trudel, and G.N. Wogan Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells Proc. Natl. Acad. Sci. USA 106 2009 14547 14551
28. S.A. Lipton Neuronal protection and destruction by NO Cell Death. Differ. 6 1999 943 951
29. M.D. Maines Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications FASEB J. 2 1988 2557 2568
30. N. Mastrodimou, F. Kiagiadaki, and K. Thermos The role of nitric oxide and cGMP in somatostatin's protection against retinal ischemia Invest. Ophthalmol. Vis. Sci. 49 2008 342 349
31. K. Mizuno, T. Koide, M. Yoshimura, and M. Araie Neuroprotective effect and intraocular penetration of nipradilol, a beta-blocker with nitric oxide donative action Invest. Ophthalmol. Vis. Sci. 42 2001 688 694
32. A. Naito, Y. Aniya, and M. Sakanashi Antioxidative action of the nitrovasodilator nicorandil: inhibition of oxidative activation of liver microsomal glutathione S-transferase and lipid peroxidation Jpn. J. Pharmacol. 65 1994 209 213
33. T. Nakazawa, H. Tomita, K. Yamaguchi, Y. Sato, M. Shimura, S. Kuwahara, and M. Tamai Neuroprotective effect of nipradilol on axotomized rat retinal ganglion cells Curr. Eye Res. 24 2002 114 122
34. R.N. Nishimura, B.E. Dwyer, and S.Y. Lu Localization of heme oxygenase in rat retina: effect of light adaptation Neurosci. Lett. 205 1996 13 16
35. J.P. Nowicki, D. Duval, H. Poignet, and B. Scatton Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse Eur. J. Pharmacol. 204 1991 339 340
36. A. Ohira, Y. Wada, M. Fujii, M. Nakamura, Y. Kasuya, Y. Hamada, and K. Shigenobu Effects of nipradilol K-351 on alpha-adrenoceptor mediated responses in various isolated tissues Arch. Int. Pharmacodyn. Ther. 278 1985 61 71
37. L.E. Otterbein, F.H. Bach, J. Alam, M. Soares, L.H. Tao, M. Wysk, R.J. Davis, R.A. Flavell, and A.M. Choi Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway Nat. Med. 6 2000 422 428
38. L.E. Otterbein, B.S. Zuckerbraun, M. Haga, F. Liu, R. Song, A. Usheva, C. Stachulak, N. Bodyak, R.N. Smith, E. Csizmadia, S. Tyagi, Y. Akamatsu, R.J. Flavell, T.R. Billiar, E. Tzeng, F.H. Bach, A.M. Choi, and M.P. Soares Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury Nat. Med. 9 2003 183 190
39. S.H. Park, J.H. Kim, Y.H. Kim, and C.K. Park Expression of neuronal nitric oxide synthase in the retina of a rat model of chronic glaucoma Vis. Res. 47 2007 2732 2740
40. K.D. Poss, and S. Tonegawa Reduced stress defense in heme oxygenase 1-deficient cells Proc. Natl. Acad. Sci. USA 94 1997 10925 10930
41. M.A. Smith, P.L. Richey Harris, L.M. Sayre, J.S. Beckman, and G. Perry Widespread peroxynitrite-mediated damage in Alzheimer's disease J. Neurosci. 17 1997 2653 2657
42. J. Sun, C. Steenbergen, and E. Murphy S-nitrosylation: NO-related redox signaling to protect against oxidative stress Antioxid. Redox Signal. 8 2006 1693 1705
43. R. Taguchi, H. Shirakawa, T. Yamaguchi, T. Kume, H. Katsuki, and A. Akaike Nitric oxide-mediated effect of nipradilol, an α- and β-adrenergic blocker, on glutamate neurotoxicity in rat cortical cultures Eur. J. Pharmacol. 535 2006 86 94
44. H. Tomita, T. Nakazawa, E. Sugano, T. Abe, and M. Tamai Nipradilol inhibits apoptosis by preventing the activation of caspase-3 via S-nitrosylation and the cGMP-dependent pathway Eur. J. Pharmacol. 452 2002 263 268
45. Y. Uchida, M. Nakamura, S. Shimizu, Y. Shirasawa, and M. Fujii Vasoactive and beta-adrenoceptor blocking properties of 3,4-dihydro-8-2-hydroxy-3- isopropylamino propoxy-3-nitroxy-2H-1-benzopyran K-351, a new antihypertensive agent Arch. Int. Pharmacodyn. Ther. 262 1983 132 149