Hydroxytyrosyl ethyl ether exhibits stronger intestinal anticarcinogenic potency and effects on transcript profiles compared to hydroxytyrosol

Food Chemistry

Volumn 138, Issue 2-3, 2013, Pages 1172-1182

  Pereira Caro, G ^a,b   Mateos, R ^a,c   Traka, M H ^a   Bacon, J R ^a   Bongaerts, R ^a   Sarria B ^c   Bravo, L ^c   Kroon, P A ^a  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b IFAPA CENTRO EL TORUÑO   (Spain)

^c INSTITUTE OF FOOD SCIENCE   (Spain)

Author keywords

Caco 2 cells; Gene expression; Hydroxytyrosol; Hydroxytyrosyl ethers; Microarrays; Transcriptome analysis; Virgin olive oil phenols

Indexed keywords

ADENOCARCINOMA CELLS; AFFYMETRIX MICROARRAYS; CACO-2 CELLS; CASPASE-3; CELL CYCLE; COLON CANCER; ETHYL ETHER; EXPOSED TO; HYDROXYTYROSOL; MOLECULAR MECHANISM; POLYPHENOLS; PROTEIN EXPRESSIONS; TRANSCRIPTOME ANALYSIS; UP-REGULATION; VIRGIN OLIVE OIL; XENOBIOTIC-METABOLIZING ENZYMES;

CELL DEATH; CELL PROLIFERATION; DETOXIFICATION; GENE EXPRESSION; GENES; MICROARRAYS; ORGANIC COMPOUNDS; PHENOLS; TRANSCRIPTION; VEGETABLE OILS;

ETHERS;

ACTIVATING TRANSCRIPTION FACTOR 3; CASPASE 3; CYCLIN B1; CYCLIN G2; CYTOCHROME P450 1A1; ETHER; GLUCURONOSYLTRANSFERASE 1A10; HYDROXYTYROSOL; HYDROXYTYROSYL ETHYL ETHER; PROTEIN BNIP3; PROTEIN P21; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE ARREST; CELL PROLIFERATION; COLON ADENOCARCINOMA; CONTROLLED STUDY; DETOXIFICATION; DRUG POTENCY; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

ANTICARCINOGENIC AGENTS; APOPTOSIS; CACO-2 CELLS; CATECHOLS; CELL CYCLE CHECKPOINTS; COLONIC NEOPLASMS; HUMANS; INTESTINES; PHENYLETHYL ALCOHOL; TRANSCRIPTOME;

EID: 84873717414     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.11.118     Document Type: Article

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