Hydroxytyrosol rich extract from olive leaves modulates cell cycle progression in MCF-7 human breast cancer cells

Food and Chemical Toxicology

Volumn 49, Issue 1, 2011, Pages 179-184

  Bouallagui, Zouhaier ^a   Han, Junkuy ^b   Isoda, Hiroko ^b   Sayadi, Sami ^a  

^a CENTRE DE BIOTECHNOLOGIE DE SFAX   (Tunisia)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Anti proliferative; Cell cycle; Cyclin D1; MCF7 cells; Olea europea

Indexed keywords

CYCLIN D1; HYDROXYTYROSOL; OLEUROPEIN; OLIVE EXTRACT; PEPTIDYLPROLYL ISOMERASE PIN1; PLANT EXTRACT; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MECHANICS; OLIVE TREE; PLANT LEAF; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

BLOTTING, WESTERN; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLOW CYTOMETRY; HUMANS; OLEA; PHENYLETHYL ALCOHOL; PLANT LEAVES; TANDEM MASS SPECTROMETRY;

OLEA EUROPAEA;

EID: 78650292220     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.10.014     Document Type: Article

References (36)

1. Abaza L., Talorete T.P.N., Yamada P., Kurita Y., Zarrouk M., Isoda H. Induction of growth inhibition and differentiation of human leukemia HL-60 cells by a Tunisian gerboui olive leaf extract. Biosci. Biotechnol. Biochem. 2007, 71:1306-1312.
2. Akihide R., Yih-Cherng L., Kun P.L., Gerburg W. Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J. Cell Sci. 2003, 116:773-783.
3. Angerosa F., d'Alessandro N., Konstantinou P., Di Giacinto L. GC-MS evaluation of phenolic compounds in virgin olive oil. J. Agric. Food Chem. 1995, 43:1802-1807.
4. Anna C., Kira S., Nazar L., Zsuzsanna O., Aracelie R., Zoltan U. Resveratrol attenuates TNF-α-induced activation of coronary arterial endothelial cells: role of NF-κ-B inhibition. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H1694-H1699.
5. Benavente-Garcia O., Castillo J., Lorente J., Ortuno A., Del Rio J.A. Antioxidant activity of phenolics extracted from Olea europaea L. Leaves. Food Chem. 2000, 68:457-462.
6. Borenfreund E., Babich H., Martin-Alguacil N. Rapid chemosensitivity assay with human normal and tumor cells in vitro. In Vitro Cell. Dev. Biol. 1990, 26:1030-1034.
7. Bouallagui Z., Sayadi S. Production of high hydroxytyrosol yields via tyrosol conversion by Pseudomonas aeruginosa immobilized resting cells. J. Agric. Food Chem. 2006, 54:9906-9911.
8. Bouaziz M., Sayadi S. Isolation and evaluation of antioxidants from leaves of a Tunisian cultivar olive tree. Eur. J. Lipid Sci. Technol. 2005, 07:97-504.
9. Bouaziz M., Grayer R.J., Simmonds Monique.S.J., Damak M., Sayadi S. Identification and antioxidant potential of flavonoids and low molecular weight phenols in olive cultivar chemlali growing in Tunisia. J. Agric. Food Chem. 2005, 53:236-241.
10. Della Ragione F., Cucciolla V., Criniti V., Indaco S., Borriello A., Zappia V. Antioxidants induce different phenotypes by a distinct modulation of signal transduction. FEBS Lett. 2002, 532:289-294.
11. Dong L., Marakovits J., Hou X., Guo C., Greasley S., Dagostino E., Ferre R.A., Catherine J.M., Kraynov E., Thomson J., Pathak V., Murray B.W. Tructure-based design of novel human Pin1 inhibitors (II). Bioorg. Med. Chem. Lett. 2010, 20:2210-2214.
12. Fabiani R., De Bartolomeo A., Rosignoli P., Servili M., Montedoro G.F., Morozzi G. Cancer chemoprevention by hydroxytyrosol isolated from virgin olive oil through G1 cell cycle arrest and apoptosis. Eur. J. Cancer Prev. 2002, 11:351-358.
13. Fabiani R., De Bartolomeo A., Rosignoli P., Servili M., Selvaggini R., Montedoro G.F., Di Saverio C., Morozz G. Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation. J. Nutr. 2006, 136:614-619.
14. Fki I., Bouaziz M., Sahnoun Z., Sayadi S. Hypocholesterolemic effects of phenolic-rich extracts of Chemlali olive cultivar in rats fed a cholesterol-rich diet. Bioorg. Med. Chem. 2005, 13:5362-5370.
15. Fujimori F., Takahashi K., Uchida C., Uchida T. Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G0 arrest. Biochem. Biophys. Res. Commun. 1999, 265:658-663.
16. Giulia C., Monica D., Alessandra I., David V., Assunta Dessi{dotless}' M., Spencer Jeremy P.E. Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochem. Biophys. Res. Commun. 2007, 362:606-611.
17. Göran L. Multiparameter analyses of cell cycle regulatory proteins in human breast cancer: A key to definition of separate pathways in tumorigenesis. Adv. Cancer Res. 2002, 84:35-56.
18. Hanbury, D., 1854. On the febrifuge properties of the olive (Olea Europaea, L). Pharm. J. Prov. Trans., 353-354.
19. International Agency for Research on Cancer, 2008. Fact sheets: http://globocan.iarc.fr.
20. Kampa M., Nifli A.P., Notas G., Castanas E. Polyphenols and cancer cell growth. Rev. Physiol. Biochem. Pharmacol. 2007, 159:79-113.
21. Karin M., Hunter T. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Current Biol. 1995, 5:747-757.
22. Kun P.L. Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics. Cancer cell. 2003, 4:175-180.
23. La Vecchia C. Mediterranean diet and cancer. Public Health Nutr. 2004, 7:965-968.
24. Lei L., Zhaoxiong Z., Xiaozhong H., Yingping Z., Lan Z., Yaxue S., Mingli S., Jiwei Z. Inhibition of peptidyl-prolyl cis/trans isomerase Pin1 induces cell cycle arrest and apoptosis in vascular smooth muscle cells. Apoptosis 2010, 15:41-54.
25. Liou Y.C., Ryo A., Huang H.K., Lu P.J., Bronson R., Fujimori F., Uchida T., Hunter T., Lu K.P. Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proc. Nat. Acad. Sci. 2002, 99:1335-1340.
26. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J. Immunol. Methods. 1983, 65:55-63.
27. Repetto G., Del Peso A., Sanz P., Repetto M. In vitro effects of lithium and nickel at different levels on Neuro-2a mouse Neuroblastoma cells. Toxicol. in vitro. 2001, 15:363-368.
28. Scheller E.F. Treatment of hypertension with standardized olive leaf extract. Med Klin. 1955, 50:327-329.
29. Singleton V.L., Rossi J.A.J. Colorimetry of Total Phenolics with Phosphomolybdic Phosphotungstic Acid Reagents. Am. J. Enol. Vitic. 1965, 16:144-158.
30. Somova L.I., Shode F.O., Ramnanan P., Nadar A. Antihypertensive, Anti-atherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies Africana leaves. J. Ethnopharmacol. 2003, 84:299-305.
31. Tahraoui A., El-Hilaly J., Israili Z.H., Lyoussi B. Ethnopharmacological survey of plants used in the traditional treatment of hypertension and diabetes in south-eastern Morocco (Errachidia province). J. Ethnopharmacol. 2007, 110:105-117.
32. Trichopoulou A., Lagiou P., Kuper H., Trichopoulos D. Cancer and Mediterranean dietary traditions. Cancer Epidemiol. Biomarkers Prev. 2000, 9:869-873.
33. Visioli F., Galli C. Biological properties of olive oil phytochemicals. Crit. Rev. Food Sci. Nutr. 2002, 42:209-221.
34. Wulf G.M., Ryo A., Wulf G.G., Lee S.W., Niu T., Lu K.P. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO Journal 2001, 20:3459-3472.
35. Wulf G., Ryo A., Liou Y.C., Lu K.P. The prolyl isomerase Pin1 in breast development and cancer. Breast Cancer Research 2003, 5:76-82.
36. Yamada P., Zarrouk M., Kawasaki K., Isoda H. Inhibitory effect of various Tunisian olive oils on chemical mediator release and cytokine production by basophilic cells. J. Ethnopharmacol. 2008, 116:279-287.