Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: Mechanistic insights by genome-wide mRNA-Seq analysis

Genes and Nutrition

Volumn 7, Issue 2, 2012, Pages 343-355

  Rafehi, Haloom ^a,b   Smith, Andrea J ^a,c   Balcerczyk, Aneta ^a   Ziemann, Mark ^a   Ooi, Jenny ^a   Loveridge, Shanon J ^a   Baker, Emma K ^a,d   El Osta, Assam ^a,b,e   Karagiannis, Tom C ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

^d ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e MONASH UNIVERSITY   (Australia)

Author keywords

Hydroxytyrosol; MRNA Seq; Olive oil; Olive polyphenol; Radioprotection

Indexed keywords

CASPASE 3; CASPASE 7; GAMMA INTERFERON RECEPTOR; GLUTAREDOXIN; GLUTATHIONE PEROXIDASE; GLYCOPROTEIN P; HEME OXYGENASE; HEME OXYGENASE 1; HISTONE H2AX; HYROXYTYROSOL; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 11; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; OLIVE OIL; POLYPHENOL; PROTEIN C JUN; SMAD7 PROTEIN; STAT3 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR ETS 1; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DEATH; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; KERATINOCYTE; OXIDATIVE STRESS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RADIATION PROTECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEQUENCE ANALYSIS; UPREGULATION;

OLEA EUROPAEA;

EID: 84860755409     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-011-0249-3     Document Type: Article

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