The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling

Journal of Thrombosis and Haemostasis

Volumn 11, Issue 2, 2013, Pages 345-356

  Cipolla, L ^a   Consonni, A ^a   Guidetti, G ^a   Canobbio, I ^a   Okigaki, M ^b   Falasca, M ^c   Ciraolo, E ^d   Hirsch, E ^d   Balduini, C ^a   Torti, M ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b KYOTO PREFECTURAL UNIVERSITY   (Japan)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

Phosphatidylinositol 3 kinase; Platelet adhesion; Rap1b; Signal transduction; Tyrosine kinases

Indexed keywords

CBL PROTEIN; FIBRINOGEN; FOCAL ADHESION KINASE 2; GUANOSINE TRIPHOSPHATASE; INTEGRIN; INTEGRIN ALPHA2B BETA3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE BETA; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RAP1B PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; THROMBOCYTE ADHESION;

ANIMALS; BLOOD PLATELETS; CELL SHAPE; ENZYME ACTIVATION; FIBRINOGEN; FOCAL ADHESION KINASE 1; FOCAL ADHESION KINASE 2; HUMANS; INTEGRIN ALPHA2; INTEGRIN BETA3; MICE; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTO-ONCOGENE PROTEINS C-ABL; PROTO-ONCOGENE PROTEINS C-AKT; RAP GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIME FACTORS;

EID: 84873547290     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12099     Document Type: Article

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