Thrombopoietin complements Gi- but not Gq-dependent pathways for integrin αIIbβ3 activation and platelet aggregation

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 24386-24395

  Campus, Francesca ^a   Lova, Paolo ^a   Bertoni, Alessandra ^b   Sinigaglia, Fabiola ^b   Balduini, Cesare ^a   Torti, Mauro ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CHEMICAL BONDS; ENZYME INHIBITION; ENZYME KINETICS; ENZYMES;

KINASE; MONOCLONAL ANTIBODY; PLATELET; THROMBOPROTEIN;

PROTEINS;

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ADRENALIN; CALCIUM; CMPL RECEPTOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FIBRINOGEN; INDOMETACIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INTEGRIN; INTEGRIN ALPHA2BBETA3; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY PAC 1; PD 98058; PHOSPHATIDYLINOSITOL 3 KINASE; PLECKSTRIN; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE C; PURINE P2Y1 RECEPTOR; PURINE P2Y12 RECEPTOR; RAP PROTEIN; RHO KINASE; THROMBOCYTE RECEPTOR; THROMBOPOIETIN; THROMBOXANE A2; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; AUTORADIOGRAPHY; CALCIUM MOBILIZATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADENOSINE DIPHOSPHATE; ANDROSTADIENES; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; BLOOD PROTEINS; CALCIUM; CHROMONES; CYCLOOXYGENASE INHIBITORS; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBRINOGEN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MORPHOLINES; PHOSPHOLIPASE C; PHOSPHOPROTEINS; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; RAP GTP-BINDING PROTEINS; RECEPTORS, CYTOKINE; RECEPTORS, PURINERGIC P2; RECEPTORS, THROMBOPOIETIN; THROMBOPOIETIN; THROMBOXANE A2; THROMBOXANES; TIME FACTORS;

EID: 21644476500     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501174200     Document Type: Article

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