PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of α(v)β3 integrin, and phosphorylated by Src kinase

Journal of Clinical Investigation

Volumn 102, Issue 5, 1998, Pages 881-892

  Duong, Le T ^a   Lakkakorpi, Päivi T ^a   Nakamura, Ichiro ^a   Machwate, Mohamed ^a   Nagy, Rose M ^a   Rodan, Gideon A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Bone resorption; Clear zone; Podosome; Tyrosine kinase; Vitronectin receptor

Indexed keywords

INTEGRIN; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CYTOSKELETON; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL;

EID: 0032168740     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI3212     Document Type: Article

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