메뉴 건너뛰기




Volumn 129, Issue 2, 2011, Pages 361-372

Ras-related protein 1 and the insulin-like growth factor type i receptor are associated with risk of progression in patients diagnosed with carcinoma in situ

Author keywords

Breast; Cancer in situ; IGF IR; Invasion; Small GTPase Rap1

Indexed keywords

RAP1 PROTEIN; SOMATOMEDIN C RECEPTOR;

EID: 80052645527     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1227-y     Document Type: Article
Times cited : (13)

References (62)
  • 4
    • 0642372572 scopus 로고    scopus 로고
    • The finding of invasive cancer after a preoperative diagnosis of ductal carcinoma-in-situ: Causes of ductal carcinoma-in-situ underestimates with stereotactic 14-gauge needle biopsy
    • DOI 10.1245/ASO.2003.11.011
    • LE Hoorntje ME Schipper PH Peeters F Bellot RK Storm RI Borel 2003 The finding of invasive cancer after a preoperative diagnosis of ductal carcinoma-in situ: causes of ductal carcinoma-in situ underestimates with stereotactic 14-gauge needle biopsy Ann Surg Oncol 10 748 753 12900365 10.1245/ASO.2003.11. 011 (Pubitemid 40486874)
    • (2003) Annals of Surgical Oncology , vol.10 , Issue.7 , pp. 748-753
    • Hoorntje, L.E.1    Schipper, M.E.I.2    Peeters, P.H.M.3    Bellot, F.4    Storm, R.K.5    Borel Rinkes, I.H.M.6
  • 5
    • 33750065712 scopus 로고    scopus 로고
    • Predictors of invasion in patients with core-needle biopsy-diagnosed ductal carcinoma in situ and recommendations for a selective approach to sentinel lymph node biopsy in ductal carcinoma in situ
    • DOI 10.1002/cncr.22216
    • L Huo N Sneige KK Hunt CT Albarracin A Lopez E Resetkova 2006 Predictors of invasion in patients with core-needle biopsy-diagnosed ductal carcinoma in situ and recommendations for a selective approach to sentinel lymph node biopsy in ductal carcinoma in situ Cancer 107 1760 1768 16977650 10.1002/cncr.22216 (Pubitemid 44582944)
    • (2006) Cancer , vol.107 , Issue.8 , pp. 1760-1768
    • Huo, L.1    Sneige, N.2    Hunt, K.K.3    Albarracin, C.T.4    Lopez, A.5    Resetkova, E.6
  • 6
    • 34547808207 scopus 로고    scopus 로고
    • Risk of invasion and axillary lymph node metastasis in ductal carcinoma in situ diagnosed by core-needle biopsy
    • DOI 10.1002/bjs.5735
    • P Meijnen HS Oldenburg CE Loo OE Nieweg JL Peterse EJ Rutgers 2007 Risk of invasion and axillary lymph node metastasis in ductal carcinoma in situ diagnosed by core-needle biopsy Br J Surg 94 952 956 17440955 10.1002/bjs.5735 1:STN:280:DC%2BD2svisF2isw%3D%3D (Pubitemid 47236538)
    • (2007) British Journal of Surgery , vol.94 , Issue.8 , pp. 952-956
    • Meijnen, P.1    Oldenburg, H.S.A.2    Loo, C.E.3    Nieweg, O.E.4    Peterse, J.L.5    Rutgers, E.J.T.6
  • 7
    • 0036155340 scopus 로고    scopus 로고
    • Predicting invasion in the excision specimen from breast core needle biopsy specimens with only ductal carcinoma in situ
    • AA Renshaw 2002 Predicting invasion in the excision specimen from breast core needle biopsy specimens with only ductal carcinoma in situ Arch Pathol Lab Med 126 39 41 11800645 (Pubitemid 34087630)
    • (2002) Archives of Pathology and Laboratory Medicine , vol.126 , Issue.1 , pp. 39-41
    • Renshaw, A.A.1
  • 9
    • 0025183156 scopus 로고
    • Heterogeneity of the motility responses in malignant tumor cells: A biological basis for the diversity and homing of metastatic cells
    • DOI 10.1002/ijc.2910460225
    • EC Kohn EA Francis LA Liotta E Schiffmann 1990 Heterogeneity of the motility responses in malignant tumor cells: a biological basis for the diversity and homing of metastatic cells Int J Cancer 46 287 292 2116998 10.1002/ijc.2910460225 1:STN:280:DyaK3czks1ClsA%3D%3D (Pubitemid 20252092)
    • (1990) International Journal of Cancer , vol.46 , Issue.2 , pp. 287-292
    • Kohn, E.C.1    Francis, E.A.2    Liotta, L.A.3    Schiffmann, E.4
  • 10
    • 0030028186 scopus 로고    scopus 로고
    • The roles of integrins and extracellular matrix proteins in the insulin- like growth factor I-stimulated chemotaxis of human breast cancer cells
    • DOI 10.1074/jbc.271.5.2443
    • ME Doerr JI Jones 1996 The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells J Biol Chem 271 2443 2447 8576205 10.1074/jbc.271.5.2443 1:CAS:528:DyaK28XptVKmtA%3D%3D (Pubitemid 26047847)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.5 , pp. 2443-2447
    • Doerr, M.E.1    Jones, J.I.2
  • 11
    • 0031585866 scopus 로고    scopus 로고
    • Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote e-cadherin-mediated cell-cell adhesion in human breast cancer cells
    • DOI 10.1006/excr.1996.3457
    • MA Guvakova E Surmacz 1997 Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells Exp Cell Res 231 149 162 9056422 10.1006/excr.1996.3457 1:CAS:528:DyaK2sXhsVKktL4%3D (Pubitemid 27187524)
    • (1997) Experimental Cell Research , vol.231 , Issue.1 , pp. 149-162
    • Guvakova, M.A.1    Surmacz, E.2
  • 12
    • 0033567935 scopus 로고    scopus 로고
    • Signal transduction by β1 integrin receptors in human chondrocytes in vitro: Collaboration with the insulin-like growth factor-I receptor
    • DOI 10.1042/0264-6021:3420615
    • M Shakibaei T John P De Souza R Rahmanzadeh HJ Merker 1999 Signal transduction by beta1 integrin receptors in human chondrocytes in vitro: collaboration with the insulin-like growth factor-I receptor Biochem J 342 Pt 3 615 623 10477272 10.1042/0264-6021:3420615 1:CAS:528:DyaK1MXmsVygs78%3D (Pubitemid 29452646)
    • (1999) Biochemical Journal , vol.342 , Issue.3 , pp. 615-623
    • Shakibaei, M.1    John, T.2    De Souza, P.3    Rahmanzadeh, R.4    Merker, H.-J.5
  • 13
    • 0028641601 scopus 로고
    • Association of insulin receptor substrate-1 with integrins
    • 7527156 10.1126/science.7527156 1:CAS:528:DyaK2MXisVGlsrk%3D
    • K Vuori E Ruoslahti 1994 Association of insulin receptor substrate-1 with integrins Science 266 1576 1578 7527156 10.1126/science.7527156 1:CAS:528:DyaK2MXisVGlsrk%3D
    • (1994) Science , vol.266 , pp. 1576-1578
    • Vuori, K.1    Ruoslahti, E.2
  • 14
    • 0036559535 scopus 로고    scopus 로고
    • Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
    • DOI 10.1016/S1535-6108(02)00055-7
    • T Lopez D Hanahan 2002 Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis Cancer Cell 1 339 353 12086849 10.1016/S1535-6108(02)00055-7 1:CAS:528:DC%2BD38XktlSrtLc%3D (Pubitemid 41039136)
    • (2002) Cancer Cell , vol.1 , Issue.4 , pp. 339-353
    • Lopez, T.1    Hanahan, D.2
  • 16
    • 0034668185 scopus 로고    scopus 로고
    • Inhibition of the type i insulin-like growth factor receptor expression and signaling: Novel strategies for antimetastatic therapy
    • 11007947 10.1016/S0006-2952(00)00422-6 1:CAS:528:DC%2BD3cXmslOjsb0%3D
    • P Brodt A Samani R Navab 2000 Inhibition of the type I insulin-like growth factor receptor expression and signaling: novel strategies for antimetastatic therapy Biochem Pharmacol 60 1101 1107 11007947 10.1016/S0006-2952(00)00422-6 1:CAS:528:DC%2BD3cXmslOjsb0%3D
    • (2000) Biochem Pharmacol , vol.60 , pp. 1101-1107
    • Brodt, P.1    Samani, A.2    Navab, R.3
  • 17
    • 0035504405 scopus 로고    scopus 로고
    • Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines
    • DOI 10.1038/sj.onc.1204920
    • JG Jackson X Zhang T Yoneda D Yee 2001 Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines Oncogene 20 7318 7325 11704861 10.1038/sj.onc.1204920 1:CAS:528:DC%2BD3MXovVOntL0%3D (Pubitemid 33078202)
    • (2001) Oncogene , vol.20 , Issue.50 , pp. 7318-7325
    • Jackson, J.G.1    Zhang, X.2    Yoneda, T.3    Yee, D.4
  • 19
    • 0030670432 scopus 로고    scopus 로고
    • The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue
    • DOI 10.1002/(SICI)1096-9896(199712)183:4<412::AID-PATH944>3.0.CO;2- 4
    • LC Happerfield DW Miles DM Barnes LL Thomsen P Smith A Hanby 1997 The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue J Pathol 183 412 417 9496257 10.1002/(SICI)1096- 9896(199712)183:4<412::AID-PATH944>3.0.CO;2-4 1:STN:280: DyaK1c7lslensA%3D%3D (Pubitemid 27509247)
    • (1997) Journal of Pathology , vol.183 , Issue.4 , pp. 412-417
    • Happerfield, L.C.1    Miles, D.W.2    Barnes, D.M.3    Thomsen, L.L.4    Smith, P.5    Hanby, A.M.6
  • 20
    • 0032521210 scopus 로고    scopus 로고
    • Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer
    • JL Resnik DB Reichart K Huey NJ Webster BL Seely 1998 Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer Cancer Res 58 1159 1164 9515800 1:CAS:528: DyaK1cXhvV2rsrs%3D (Pubitemid 28183203)
    • (1998) Cancer Research , vol.58 , Issue.6 , pp. 1159-1164
    • Resnik, J.L.1    Reichart, D.B.2    Huey, K.3    Webster, N.J.G.4    Seely, B.L.5
  • 21
    • 10944249457 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor 1 receptor in primary breast cancer: Immunohistochemical analysis
    • DOI 10.1016/j.humpath.2004.09.005, PII S0046817704004988
    • C Shimizu T Hasegawa Y Tani F Takahashi M Takeuchi T Watanabe M Ando N Katsumata Y Fujiwara 2004 Expression of insulin-like growth factor 1 receptor in primary breast cancer: immunohistochemical analysis Hum Pathol 35 1537 1542 15619214 10.1016/j.humpath.2004.09.005 1:CAS:528:DC%2BD2cXhtVyku7%2FE (Pubitemid 40017995)
    • (2004) Human Pathology , vol.35 , Issue.12 , pp. 1537-1542
    • Shimizu, C.1    Hasegawa, T.2    Tani, Y.3    Takahashi, F.4    Takeuchi, M.5    Watanabe, T.6    Ando, M.7    Katsumata, N.8    Fujiwara, Y.9
  • 22
    • 9144223655 scopus 로고    scopus 로고
    • Expression of the Insulin-Like Growth Factor I Receptor and Urokinase Plasminogen Activator in Breast Cancer Is Associated with Poor Survival: Potential for Intervention with 17-Allylamino Geldanamycin
    • DOI 10.1158/0008-5472.CAN-03-1242
    • TO Nielsen HN Andrews M Cheang JE Kucab FD Hsu J Ragaz CB Gilks N Makretsov CD Bajdik C Brookes LM Neckers V Evdokimova DG Huntsman SE Dunn 2004 Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin Cancer Res 64 286 291 14729636 10.1158/0008-5472.CAN-03-1242 1:CAS:528:DC%2BD2cXkslyktg%3D%3D (Pubitemid 38114109)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 286-291
    • Nielsen, T.O.1    Andrews, H.N.2    Cheang, M.3    Kucab, J.E.4    Hsu, F.D.5    Ragaz, J.6    Gilks, C.B.7    Makretsov, N.8    Bajdik, C.D.9    Brookes, C.10    Neckers, L.M.11    Evdokimova, V.12    Huntsman, D.G.13    Dunn, S.E.14
  • 23
    • 0037277516 scopus 로고    scopus 로고
    • Relationship between growth factor signaling and motility in aggressive cancers
    • DOI 10.1186/bcr598
    • KL van Golen 2003 Inflammatory breast cancer: relationship between growth factor signaling and motility in aggressive cancers Breast Cancer Res 5 174 179 12793901 10.1186/bcr598 (Pubitemid 36519413)
    • (2003) Breast Cancer Research , vol.5 , Issue.3 , pp. 174-179
    • Van Golen, K.L.1
  • 24
    • 56749110996 scopus 로고    scopus 로고
    • The type 1 insulin-like growth factor receptor pathway
    • 18927274 10.1158/1078-0432.CCR-07-4879 1:CAS:528:DC%2BD1cXht1KgtbrP
    • MM Chitnis JS Yuen AS Protheroe M Pollak VM Macaulay 2008 The type 1 insulin-like growth factor receptor pathway Clin Cancer Res 14 6364 6370 18927274 10.1158/1078-0432.CCR-07-4879 1:CAS:528:DC%2BD1cXht1KgtbrP
    • (2008) Clin Cancer Res , vol.14 , pp. 6364-6370
    • Chitnis, M.M.1    Yuen, J.S.2    Protheroe, A.S.3    Pollak, M.4    MacAulay, V.M.5
  • 25
    • 33751503046 scopus 로고    scopus 로고
    • Regulation of the RAP1/RAF-1/extracellularly regulated kinase-1/2 cascade and prolactin release by the phosphoinositide 3-kinase/AKT pathway in pituitary cells
    • DOI 10.1210/en.2006-0325
    • D Romano M Pertuit R Rasolonjanahary JV Barnier K Magalon A Enjalbert C Gerard 2006 Regulation of the RAP1/RAF-1/extracellularly regulated kinase-1/2 cascade and prolactin release by the phosphoinositide 3-kinase/AKT pathway in pituitary cells Endocrinology 147 6036 6045 16935846 10.1210/en.2006-0325 1:CAS:528:DC%2BD28Xht1yqtrvM (Pubitemid 44833523)
    • (2006) Endocrinology , vol.147 , Issue.12 , pp. 6036-6045
    • Romano, D.1    Pertuit, M.2    Rasolonjanahary, R.3    Barnier, J.-V.4    Magalon, K.5    Enjalbert, A.6    Gerard, C.7
  • 26
    • 80052626660 scopus 로고    scopus 로고
    • Tuberin and hamartin in moving breast cancer cells expression localization and function
    • T. Abreu G. Silva (eds). Nova Science Publishers New York
    • Guvakova MA, Lee WSY (2009) Tuberin and hamartin in moving breast cancer cells expression localization and function. In: Abreu T, Silva G (eds) Cell movement new research trends. Nova Science Publishers, New York, pp 187-207
    • (2009) Cell Movement New Research Trends , pp. 187-207
    • Guvakova, M.A.1    Lee, W.S.Y.2
  • 27
    • 33645973538 scopus 로고    scopus 로고
    • Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins
    • 16213650 10.1016/j.biochi.2005.08.007 1:CAS:528:DC%2BD28Xjs1aiu7s%3D
    • S Paganini GF Guidetti S Catricala P Trionfini S Panelli C Balduini M Torti 2006 Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins Biochimie 88 285 295 16213650 10.1016/j.biochi.2005.08.007 1:CAS:528:DC%2BD28Xjs1aiu7s%3D
    • (2006) Biochimie , vol.88 , pp. 285-295
    • Paganini, S.1    Guidetti, G.F.2    Catricala, S.3    Trionfini, P.4    Panelli, S.5    Balduini, C.6    Torti, M.7
  • 28
    • 0035347262 scopus 로고    scopus 로고
    • Rap1 signalling: Adhering to new models
    • DOI 10.1038/35073073
    • JL Bos J de Rooij KA Reedquist 2001 Rap1 signalling: adhering to new models Nat Rev Mol Cell Biol 2 369 377 11331911 10.1038/35073073 1:CAS:528:DC%2BD3MXjs1Chu7g%3D (Pubitemid 33674049)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.5 , pp. 369-377
    • Bos, J.L.1    De Rooij, J.2    Reedquist, K.A.3
  • 29
    • 0027458513 scopus 로고
    • Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins
    • GM Bokoch 1993 Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins Biochem J 289 Pt 1 17 24 8424755 1:CAS:528:DyaK3sXnsFCmtg%3D%3D (Pubitemid 23040802)
    • (1993) Biochemical Journal , vol.289 , Issue.1 , pp. 17-24
    • Bokoch, G.M.1
  • 30
    • 15044359236 scopus 로고    scopus 로고
    • Linking Rap to cell adhesion
    • DOI 10.1016/j.ceb.2005.02.009, Cell Regulation
    • JL Bos 2005 Linking Rap to cell adhesion Curr Opin Cell Biol 17 123 128 15780587 10.1016/j.ceb.2005.02.009 1:CAS:528:DC%2BD2MXisVCqtLk%3D (Pubitemid 40380934)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.2 , pp. 123-128
    • Bos, J.L.1
  • 31
    • 0037329747 scopus 로고    scopus 로고
    • Cellular functions of the Rap1 GTP-binding protein: A pattern emerges
    • DOI 10.1242/jcs.00238
    • E Caron 2003 Cellular functions of the Rap1 GTP-binding protein: a pattern emerges J Cell Sci 116 435 440 12508104 10.1242/jcs.00238 1:CAS:528:DC%2BD3sXhtlOgsro%3D (Pubitemid 36231283)
    • (2003) Journal of Cell Science , vol.116 , Issue.3 , pp. 435-440
    • Caron, E.1
  • 32
    • 0142024483 scopus 로고    scopus 로고
    • Rap1 GTPase: Functions, Regulation, and Malignancy
    • DOI 10.1093/jb/mvg180
    • M Hattori N Minato 2003 Rap1 GTPase: functions, regulation, and malignancy J Biochem 134 479 484 14607972 10.1093/jb/mvg180 1:CAS:528: DC%2BD3sXhtVWgtb3K (Pubitemid 37442869)
    • (2003) Journal of Biochemistry , vol.134 , Issue.4 , pp. 479-484
    • Hattori, M.1    Minato, N.2
  • 33
    • 77649191184 scopus 로고    scopus 로고
    • Rap1, a mercenary among the Ras-like GTPases
    • 20060392 10.1016/j.ydbio.2009.12.043 1:CAS:528:DC%2BC3cXivFGrt74%3D
    • EW Frische FJ Zwartkruis 2010 Rap1, a mercenary among the Ras-like GTPases Dev Biol 340 1 9 20060392 10.1016/j.ydbio.2009.12.043 1:CAS:528:DC%2BC3cXivFGrt74%3D
    • (2010) Dev Biol , vol.340 , pp. 1-9
    • Frische, E.W.1    Zwartkruis, F.J.2
  • 34
    • 0030680228 scopus 로고    scopus 로고
    • Alterations in the rap1 signaling pathway are common in human gliomas
    • DH Gutmann S Saporito-Irwin JE De Clue R Wienecke A Guha 1997 Alterations in the rap1 signaling pathway are common in human gliomas Oncogene 15 1611 1616 9380414 10.1038/sj.onc.1201314 1:CAS:528:DyaK2sXmslyntLs%3D (Pubitemid 27464655)
    • (1997) Oncogene , vol.15 , Issue.13 , pp. 1611-1616
    • Gutmann, D.H.1    Saporito-Irwin, S.2    DeClue, J.E.3    Wienecke, R.4    Guha, A.5
  • 35
    • 22144438660 scopus 로고    scopus 로고
    • Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: The role of promoter methylation of TSC genes
    • DOI 10.1016/j.ejca.2005.03.023, PII S0959804905003266
    • WG Jiang J Sampson TA Martin L Lee-Jones G Watkins A Douglas-Jones K Mokbel RE Mansel 2005 Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: the role of promoter methylation of TSC genes Eur J Cancer 41 1628 1636 15951164 10.1016/j.ejca.2005.03.023 1:CAS:528:DC%2BD2MXmsVCmurk%3D (Pubitemid 40981846)
    • (2005) European Journal of Cancer , vol.41 , Issue.11 , pp. 1628-1636
    • Jiang, W.G.1    Sampson, J.2    Martin, T.A.3    Lee-Jones, L.4    Watkins, G.5    Douglas-Jones, A.6    Mokbel, K.7    Mansel, R.E.8
  • 40
    • 2342597085 scopus 로고    scopus 로고
    • Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL
    • DOI 10.1016/j.imlet.2004.02.008, PII S0165247804000409
    • T Kinashi K Katagiri 2004 Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL Immunol Lett 93 1 5 15134891 10.1016/j.imlet.2004.02.008 1:CAS:528:DC%2BD2cXjvVeqs7c%3D (Pubitemid 38591512)
    • (2004) Immunology Letters , vol.93 , Issue.1 , pp. 1-5
    • Kinashi, T.1    Katagiri, K.2
  • 41
    • 14244260906 scopus 로고    scopus 로고
    • Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes
    • DOI 10.1074/jbc.M409701200
    • H Fujita S Fukuhara A Sakurai A Yamagishi Y Kamioka Y Nakaoka M Masuda N Mochizuki 2005 Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes J Biol Chem 280 5022 5031 15569673 10.1074/jbc.M409701200 1:CAS:528:DC%2BD2MXhtVymur8%3D (Pubitemid 40288678)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.6 , pp. 5022-5031
    • Fujita, H.1    Fukuhara, S.2    Sakurai, A.3    Yamagishi, A.4    Kamioka, Y.5    Nakaoka, Y.6    Masuda, M.7    Mochizuki, N.8
  • 42
    • 44449172648 scopus 로고    scopus 로고
    • Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells
    • DOI 10.1111/j.1365-2443.2008.01187.x
    • M Takahashi Y Rikitake Y Nagamatsu T Hara W Ikeda K Hirata Y Takai 2008 Sequential activation of Rap1 and Rac1 small G proteins by PDGF locally at leading edges of NIH3T3 cells Genes Cells 13 549 569 18422604 10.1111/j.1365-2443.2008.01187.x 1:CAS:528:DC%2BD1cXntlams7w%3D (Pubitemid 351761773)
    • (2008) Genes to Cells , vol.13 , Issue.6 , pp. 549-569
    • Takahashi, M.1    Rikitake, Y.2    Nagamatsu, Y.3    Hara, T.4    Ikeda, W.5    Hirata, K.-I.6    Takai, Y.7
  • 43
    • 34250304220 scopus 로고    scopus 로고
    • Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells
    • DOI 10.1158/0008-5472.CAN-06-4246
    • M Itoh CM Nelson CA Myers MJ Bissell 2007 Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells Cancer Res 67 4759 4766 17510404 10.1158/0008-5472.CAN-06-4246 1:CAS:528:DC%2BD2sXltl2gs7s%3D (Pubitemid 46910183)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4759-4766
    • Itoh, M.1    Nelson, C.M.2    Myers, C.A.3    Bissell, M.J.4
  • 45
    • 33846629961 scopus 로고    scopus 로고
    • Quantitative protein analysis from formalin-fixed tissues: Implications for translational clinical research and nanoscale molecular diagnosis
    • DOI 10.1002/path.2107
    • KF Becker C Schott S Hipp V Metzger P Porschewski R Beck J Nahrig I Becker H Hofler 2007 Quantitative protein analysis from formalin-fixed tissues: implications for translational clinical research and nanoscale molecular diagnosis J Pathol 211 370 378 17133373 10.1002/path.2107 1:CAS:528: DC%2BD2sXisFyksb4%3D (Pubitemid 46172713)
    • (2007) Journal of Pathology , vol.211 , Issue.3 , pp. 370-378
    • Becker, K.-F.1    Schott, C.2    Hipp, S.3    Metzger, V.4    Porschewski, P.5    Beck, R.6    Nahrig, J.7    Becker, I.8    Hofler, H.9
  • 46
    • 0022504347 scopus 로고
    • Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors
    • KS McCarty Jr E Szabo JL Flowers EB Cox GS Leight L Miller J Konrath JT Soper DA Budwit WT Creasman 1986 Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors Cancer Res 46 4244s 4248s 3524805 (Pubitemid 16041242)
    • (1986) Cancer Research , vol.46 , Issue.8 SUPPL.
    • McCarty Jr., K.S.1    Szabo, E.2    Flowers, J.L.3
  • 47
    • 33745950635 scopus 로고    scopus 로고
    • Immunohistochemistry and quantitative analysis of protein expression
    • M Cregger AJ Berger DL Rimm 2006 Immunohistochemistry and quantitative analysis of protein expression Arch Pathol Lab Med 130 1026 1030 16831029 1:CAS:528:DC%2BD28XnslKnsLo%3D (Pubitemid 44061434)
    • (2006) Archives of Pathology and Laboratory Medicine , vol.130 , Issue.7 , pp. 1026-1030
    • Cregger, M.1    Berger, A.J.2    Rimm, D.L.3
  • 48
    • 34147147018 scopus 로고    scopus 로고
    • Insulin-like growth factors control cell migration in health and disease
    • DOI 10.1016/j.biocel.2006.10.013, PII S1357272506003098
    • MA Guvakova 2007 Insulin-like growth factors control cell migration in health and disease Int J Biochem Cell Biol 39 890 909 17113337 10.1016/j.biocel.2006.10.013 1:CAS:528:DC%2BD2sXksFaisbo%3D (Pubitemid 46575318)
    • (2007) International Journal of Biochemistry and Cell Biology , vol.39 , Issue.5 , pp. 890-909
    • Guvakova, M.A.1
  • 49
    • 77951709259 scopus 로고    scopus 로고
    • Targeting the insulin-like growth factor receptor-1R pathway for cancer therapy
    • 20388853 10.1158/1078-0432.CCR-09-2232 1:CAS:528:DC%2BC3cXltlegtr0%3D
    • J Zha MR Lackner 2010 Targeting the insulin-like growth factor receptor-1R pathway for cancer therapy Clin Cancer Res 16 2512 2517 20388853 10.1158/1078-0432.CCR-09-2232 1:CAS:528:DC%2BC3cXltlegtr0%3D
    • (2010) Clin Cancer Res , vol.16 , pp. 2512-2517
    • Zha, J.1    Lackner, M.R.2
  • 50
    • 0036149044 scopus 로고    scopus 로고
    • Molecular alterations in ductal carcinoma in situ of the breast
    • DOI 10.1097/00001622-200201000-00016
    • K Polyak 2002 Molecular alterations in ductal carcinoma in situ of the breast Curr Opin Oncol 14 92 96 11790987 10.1097/00001622-200201000-00016 1:CAS:528:DC%2BD38XnsVSqsw%3D%3D (Pubitemid 34072970)
    • (2002) Current Opinion in Oncology , vol.14 , Issue.1 , pp. 92-96
    • Polyak, K.1
  • 51
    • 43049117148 scopus 로고    scopus 로고
    • The molecular journey from ductal carcinoma in situ to invasive breast cancer
    • DOI 10.1002/cncr.23430
    • L Wiechmann HM Kuerer 2008 The molecular journey from ductal carcinoma in situ to invasive breast cancer Cancer 112 2130 2142 18383519 10.1002/cncr.23430 (Pubitemid 351628621)
    • (2008) Cancer , vol.112 , Issue.10 , pp. 2130-2142
    • Wiechmann, L.1    Kuerer, H.M.2
  • 52
    • 57149146434 scopus 로고    scopus 로고
    • The role of endocrine insulin-like growth factor-I and insulin in breast cancer
    • 19030972 10.1007/s10911-008-9100-x
    • D Lann D LeRoith 2008 The role of endocrine insulin-like growth factor-I and insulin in breast cancer J Mammary Gland Biol Neoplasia 13 371 379 19030972 10.1007/s10911-008-9100-x
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 371-379
    • Lann, D.1    Leroith, D.2
  • 53
    • 0034693680 scopus 로고    scopus 로고
    • Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer
    • 11102895 10.1002/1097-0215(20001120)89:6<506::AID-IJC7>3.0.CO;2-F 1:CAS:528:DC%2BD3cXptVejs74%3D
    • B Schnarr K Strunz J Ohsam A Benner J Wacker D Mayer 2000 Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer Int J Cancer 89 506 513 11102895 10.1002/1097-0215(20001120)89:6<506::AID-IJC7>3.0.CO;2-F 1:CAS:528:DC%2BD3cXptVejs74%3D
    • (2000) Int J Cancer , vol.89 , pp. 506-513
    • Schnarr, B.1    Strunz, K.2    Ohsam, J.3    Benner, A.4    Wacker, J.5    Mayer, D.6
  • 54
    • 0023779434 scopus 로고
    • Insulin-like growth factor 1 receptors in human breast cancer and their relation to estradiol and progesterone receptors
    • 2972358 1:CAS:528:DyaL1MXlsFWi
    • JP Peyrat J Bonneterre R Beuscart J Djiane A Demaille 1988 Insulin-like growth factor 1 receptors in human breast cancer and their relation to estradiol and progesterone receptors Cancer Res 48 6429 6433 2972358 1:CAS:528: DyaL1MXlsFWi
    • (1988) Cancer Res , vol.48 , pp. 6429-6433
    • Peyrat, J.P.1    Bonneterre, J.2    Beuscart, R.3    Djiane, J.4    Demaille, A.5
  • 55
    • 33947121226 scopus 로고    scopus 로고
    • Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation
    • DOI 10.1038/sj.onc.1209955, PII 1209955
    • RA Jones CI Campbell EJ Gunther LA Chodosh JJ Petrik R Khokha RA Moorehead 2007 Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation Oncogene 26 1636 1644 16953219 10.1038/sj.onc.1209955 1:CAS:528:DC%2BD2sXisFynsb4%3D (Pubitemid 46398739)
    • (2007) Oncogene , vol.26 , Issue.11 , pp. 1636-1644
    • Jones, R.A.1    Campbell, C.I.2    Gunther, E.J.3    Chodosh, L.A.4    Petrik, J.J.5    Khokha, R.6    Moorehead, R.A.7
  • 56
    • 0842281886 scopus 로고    scopus 로고
    • Role of IGF-1R in mediating breast cancer invasion and metastasis
    • JE Kucab SE Dunn 2003 Role of IGF-1R in mediating breast cancer invasion and metastasis Breast Dis 17 41 47 15687676 1:CAS:528:DC%2BD2cXnsFGktQ%3D%3D (Pubitemid 38180807)
    • (2003) Breast Disease , vol.17 , pp. 41-47
    • Kucab, J.E.1    Dunn, S.E.2
  • 58
    • 28544444712 scopus 로고    scopus 로고
    • Type I insulin-like growth factor receptor as a therapeutic target in cancer
    • DOI 10.1158/0008-5472.CAN-05-2752
    • BS Miller D Yee 2005 Type I insulin-like growth factor receptor as a therapeutic target in cancer Cancer Res 65 10123 10127 16287993 10.1158/0008-5472.CAN-05-2752 1:CAS:528:DC%2BD2MXht1WgurjF (Pubitemid 41743697)
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10123-10127
    • Miller, B.S.1    Yee, D.2
  • 59
    • 36048980334 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor pathways
    • D Yee 2007 Targeting insulin-like growth factor pathways Br J Cancer 96 Supp l 7 10
    • (2007) Br J Cancer , vol.96 , Issue.SUPPL. , pp. 7-10
    • Yee, D.1
  • 60
    • 54049108939 scopus 로고    scopus 로고
    • Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: Lessons from the first clinical trials
    • 18790742 10.1158/1535-7163.MCT-08-0265 1:CAS:528:DC%2BD1cXhtFSms7jJ
    • J Rodon V De Santos RJ Ferry Jr R Kurzrock 2008 Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: lessons from the first clinical trials Mol Cancer Ther 7 2575 2588 18790742 10.1158/1535-7163.MCT-08-0265 1:CAS:528:DC%2BD1cXhtFSms7jJ
    • (2008) Mol Cancer Ther , vol.7 , pp. 2575-2588
    • Rodon, J.1    De Santos, V.2    Ferry Jr., R.J.3    Kurzrock, R.4
  • 62
    • 0347320784 scopus 로고    scopus 로고
    • Geranylgeranyltransferase I Inhibitor GGTI-2154 Induces Breast Carcinoma Apoptosis and Tumor Regression in H-Ras Transgenic Mice
    • J Sun J Ohkanda D Coppola H Yin M Kothare B Busciglio AD Hamilton SM Sebti 2003 Geranylgeranyltransferase I inhibitor GGTI-2154 induces breast carcinoma apoptosis and tumor regression in H-Ras transgenic mice Cancer Res 63 8922 8929 14695209 1:CAS:528:DC%2BD3sXhtVSqtbjN (Pubitemid 38064072)
    • (2003) Cancer Research , vol.63 , Issue.24 , pp. 8922-8929
    • Sun, J.1    Ohkanda, J.2    Coppola, D.3    Yin, H.4    Kothare, M.5    Busciglio, B.6    Hamilton, A.D.7    Sebti, S.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.