Specific inhibition of caspase-3 by a competitive DARPin: Molecular mimicry between native and designed inhibitors

Structure

Volumn 21, Issue 2, 2013, Pages 277-289

  Schroeder, Thilo ^a   Barandun, Jonas ^a   Flütsch, Andreas ^a   Briand, Christophe ^a   Mittl, Peer R E ^a   Grütter, Markus G ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 7; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; KINETICS; MOLECULAR MIMICRY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANKYRIN REPEAT; BINDING, COMPETITIVE; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE INHIBITORS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEINS;

EID: 84873414491     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.12.011     Document Type: Article

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