-
2
-
-
33645732219
-
Molecular pathology of malignant gliomas
-
D.N. Louis Molecular pathology of malignant gliomas Annu Rev Pathol 1 2006 97 117
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 97-117
-
-
Louis, D.N.1
-
3
-
-
80052023881
-
The neurobiology of gliomas: From cell biology to the development of therapeutic approaches
-
M. Westphal, and K. Lamszus The neurobiology of gliomas: from cell biology to the development of therapeutic approaches Nat Rev Neurosci 12 2011 495 508
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 495-508
-
-
Westphal, M.1
Lamszus, K.2
-
4
-
-
84861460670
-
Development of robust discriminant equations for assessing subtypes of glioblastoma biopsies
-
X. Castells, J.J. Acebes, C. Majos, S. Boluda, M. Julia-Sape, and A.P. Candiota Development of robust discriminant equations for assessing subtypes of glioblastoma biopsies Br J Cancer 106 2012 1816 1825
-
(2012)
Br J Cancer
, vol.106
, pp. 1816-1825
-
-
Castells, X.1
Acebes, J.J.2
Majos, C.3
Boluda, S.4
Julia-Sape, M.5
Candiota, A.P.6
-
5
-
-
4644313275
-
Gene expression profiling of gliomas strongly predicts survival
-
W.A. Freije, F.E. Castro-Vargas, Z. Fang, S. Horvath, T. Cloughesy, and L.M. Liau Gene expression profiling of gliomas strongly predicts survival Cancer Res 64 2004 6503 6510
-
(2004)
Cancer Res
, vol.64
, pp. 6503-6510
-
-
Freije, W.A.1
Castro-Vargas, F.E.2
Fang, Z.3
Horvath, S.4
Cloughesy, T.5
Liau, L.M.6
-
6
-
-
0037381008
-
Gene expression-based classification of malignant gliomas correlates better with survival than histological classification
-
C.L. Nutt, D.R. Mani, R.A. Betensky, P. Tamayo, J.G. Cairncross, and C. Ladd Gene expression-based classification of malignant gliomas correlates better with survival than histological classification Cancer Res 63 2003 1602 1607
-
(2003)
Cancer Res
, vol.63
, pp. 1602-1607
-
-
Nutt, C.L.1
Mani, D.R.2
Betensky, R.A.3
Tamayo, P.4
Cairncross, J.G.5
Ladd, C.6
-
7
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
H.S. Phillips, S. Kharbanda, R. Chen, W.F. Forrest, R.H. Soriano, and T.D. Wu Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis Cancer Cell 9 2006 157 173
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
-
8
-
-
0242607878
-
Virtual and real brain tumors: Using mathematical modeling to quantify glioma growth and invasion
-
K.R. Swanson, C. Bridge, J.D. Murray, and E.C. Alvord Jr. Virtual and real brain tumors: using mathematical modeling to quantify glioma growth and invasion J Neurol Sci 216 2003 1 10
-
(2003)
J Neurol Sci
, vol.216
, pp. 1-10
-
-
Swanson, K.R.1
Bridge, C.2
Murray, J.D.3
Alvord, Jr.E.C.4
-
9
-
-
38049051925
-
A mathematical modelling tool for predicting survival of individual patients following resection of glioblastoma: A proof of principle
-
K.R. Swanson, R.C. Rostomily, and E.C. Alvord Jr. A mathematical modelling tool for predicting survival of individual patients following resection of glioblastoma: a proof of principle Br J Cancer 98 2008 113 119
-
(2008)
Br J Cancer
, vol.98
, pp. 113-119
-
-
Swanson, K.R.1
Rostomily, R.C.2
Alvord, Jr.E.C.3
-
10
-
-
84255170467
-
Quantifying the role of angiogenesis in malignant progression of gliomas: In silico modeling integrates imaging and histology
-
K.R. Swanson, R.C. Rockne, J. Claridge, M.A. Chaplain, E.C. Alvord Jr., and A.R. Anderson Quantifying the role of angiogenesis in malignant progression of gliomas: in silico modeling integrates imaging and histology Cancer Res 71 2011 7366 7375
-
(2011)
Cancer Res
, vol.71
, pp. 7366-7375
-
-
Swanson, K.R.1
Rockne, R.C.2
Claridge, J.3
Chaplain, M.A.4
Alvord, Jr.E.C.5
Anderson, A.R.6
-
11
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
R. Stupp, W.P. Mason, M.J. van den Bent, M. Weller, B. Fisher, and M.J. Taphoorn Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
12
-
-
48949107730
-
Glioma extent of resection and its impact on patient outcome
-
discussion 264-6
-
N. Sanai, and M.S. Berger Glioma extent of resection and its impact on patient outcome Neurosurgery 62 2008 753 764 discussion 264-6
-
(2008)
Neurosurgery
, vol.62
, pp. 753-764
-
-
Sanai, N.1
Berger, M.S.2
-
13
-
-
33745198882
-
Chemotherapy resistance of glioblastoma stem cells
-
A. Eramo, L. Ricci-Vitiani, A. Zeuner, R. Pallini, F. Lotti, and G. Sette Chemotherapy resistance of glioblastoma stem cells Cell Death Differ 13 2006 1238 1241
-
(2006)
Cell Death Differ
, vol.13
, pp. 1238-1241
-
-
Eramo, A.1
Ricci-Vitiani, L.2
Zeuner, A.3
Pallini, R.4
Lotti, F.5
Sette, G.6
-
15
-
-
25144433295
-
High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival
-
A. van Rhenen, N. Feller, A. Kelder, A.H. Westra, E. Rombouts, and S. Zweegman High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival Clin Cancer Res 11 2005 6520 6527
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6520-6527
-
-
Van Rhenen, A.1
Feller, N.2
Kelder, A.3
Westra, A.H.4
Rombouts, E.5
Zweegman, S.6
-
16
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
17
-
-
34047096557
-
Cancer stem cells: Models and concepts
-
P. Dalerba, R.W. Cho, and M.F. Clarke Cancer stem cells: models and concepts Annu Rev Med 58 2007 267 284
-
(2007)
Annu Rev Med
, vol.58
, pp. 267-284
-
-
Dalerba, P.1
Cho, R.W.2
Clarke, M.F.3
-
18
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
J.E. Visvader, and G.J. Lindeman Cancer stem cells in solid tumours: accumulating evidence and unresolved questions Nat Rev Cancer 8 2008 755 768
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
19
-
-
77950502115
-
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
-
R. Chen, M.C. Nishimura, S.M. Bumbaca, S. Kharbanda, W.F. Forrest, and I.M. Kasman A hierarchy of self-renewing tumor-initiating cell types in glioblastoma Cancer Cell 17 2010 362 375
-
(2010)
Cancer Cell
, vol.17
, pp. 362-375
-
-
Chen, R.1
Nishimura, M.C.2
Bumbaca, S.M.3
Kharbanda, S.4
Forrest, W.F.5
Kasman, I.M.6
-
20
-
-
79951681568
-
Cancer stem cells: A new framework for the design of tumor therapies
-
B.K. Garvalov, and T. Acker Cancer stem cells: a new framework for the design of tumor therapies J Mol Med (Berl) 89 2011 95 107
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 95-107
-
-
Garvalov, B.K.1
Acker, T.2
-
21
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat Med 3 1997 730 737
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
22
-
-
0036737914
-
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
-
T.N. Ignatova, V.G. Kukekov, E.D. Laywell, O.N. Suslov, F.D. Vrionis, and D.A. Steindler Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro Glia 39 2002 193 206
-
(2002)
Glia
, vol.39
, pp. 193-206
-
-
Ignatova, T.N.1
Kukekov, V.G.2
Laywell, E.D.3
Suslov, O.N.4
Vrionis, F.D.5
Steindler, D.A.6
-
23
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
S.K. Singh, C. Hawkins, I.D. Clarke, J.A. Squire, J. Bayani, and T. Hide Identification of human brain tumour initiating cells Nature 432 2004 396 401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
-
24
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
H.D. Hemmati, I. Nakano, J.A. Lazareff, M. Masterman-Smith, D.H. Geschwind, and M. Bronner-Fraser Cancerous stem cells can arise from pediatric brain tumors Proc Natl Acad Sci U S A 100 2003 15178 15183
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
Masterman-Smith, M.4
Geschwind, D.H.5
Bronner-Fraser, M.6
-
25
-
-
79957928264
-
Cancer stem cells in gliomas: Identifying and understanding the apex cell in cancer's hierarchy
-
M. Venere, H.A. Fine, P.B. Dirks, and J.N. Rich Cancer stem cells in gliomas: identifying and understanding the apex cell in cancer's hierarchy Glia 59 2011 1148 1154
-
(2011)
Glia
, vol.59
, pp. 1148-1154
-
-
Venere, M.1
Fine, H.A.2
Dirks, P.B.3
Rich, J.N.4
-
27
-
-
0031789814
-
Neurogenesis in the adult human hippocampus
-
P.S. Eriksson, E. Perfilieva, T. Bjork-Eriksson, A.M. Alborn, C. Nordborg, and D.A. Peterson Neurogenesis in the adult human hippocampus Nat Med 4 1998 1313 1317
-
(1998)
Nat Med
, vol.4
, pp. 1313-1317
-
-
Eriksson, P.S.1
Perfilieva, E.2
Bjork-Eriksson, T.3
Alborn, A.M.4
Nordborg, C.5
Peterson, D.A.6
-
28
-
-
0033594892
-
Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis
-
D.A. Lim, and A. Alvarez-Buylla Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis Proc Natl Acad Sci U S A 96 1999 7526 7531
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7526-7531
-
-
Lim, D.A.1
Alvarez-Buylla, A.2
-
29
-
-
79957964861
-
Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor
-
O. Gonzalez-Perez, and A. Alvarez-Buylla Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor Brain Res Rev 67 2011 147 156
-
(2011)
Brain Res Rev
, vol.67
, pp. 147-156
-
-
Gonzalez-Perez, O.1
Alvarez-Buylla, A.2
-
31
-
-
79956205463
-
Lake-front property: A unique germinal niche by the lateral ventricles of the adult brain
-
R.A. Ihrie, and A. Alvarez-Buylla Lake-front property: a unique germinal niche by the lateral ventricles of the adult brain Neuron 70 2011 674 686
-
(2011)
Neuron
, vol.70
, pp. 674-686
-
-
Ihrie, R.A.1
Alvarez-Buylla, A.2
-
32
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
C. Calabrese, H. Poppleton, M. Kocak, T.L. Hogg, C. Fuller, and B. Hamner A perivascular niche for brain tumor stem cells Cancer Cell 11 2007 69 82
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
-
33
-
-
77956803700
-
The perivascular niche microenvironment in brain tumor progression
-
N. Charles, and E.C. Holland The perivascular niche microenvironment in brain tumor progression Cell Cycle 9 2010 3012 3021
-
(2010)
Cell Cycle
, vol.9
, pp. 3012-3021
-
-
Charles, N.1
Holland, E.C.2
-
34
-
-
80054986458
-
Perivascular instruction of cell genesis and fate in the adult brain
-
S.A. Goldman, and Z. Chen Perivascular instruction of cell genesis and fate in the adult brain Nat Neurosci 14 2011 1382 1389
-
(2011)
Nat Neurosci
, vol.14
, pp. 1382-1389
-
-
Goldman, S.A.1
Chen, Z.2
-
35
-
-
84860368151
-
Glioblastoma blood flow measured with stable xenon CT indicates tumor necrosis, vascularity, and brain invasion
-
M. Crocker, S. Saadoun, A. Jury, C. Jones, S. Zacharoulis, and S. Thomas Glioblastoma blood flow measured with stable xenon CT indicates tumor necrosis, vascularity, and brain invasion Neuro Oncol 14 2012 641 648
-
(2012)
Neuro Oncol
, vol.14
, pp. 641-648
-
-
Crocker, M.1
Saadoun, S.2
Jury, A.3
Jones, C.4
Zacharoulis, S.5
Thomas, S.6
-
36
-
-
77956241246
-
Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling
-
E. Kokovay, S. Goderie, Y. Wang, S. Lotz, G. Lin, and Y. Sun Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling Cell Stem Cell 7 2010 163 173
-
(2010)
Cell Stem Cell
, vol.7
, pp. 163-173
-
-
Kokovay, E.1
Goderie, S.2
Wang, Y.3
Lotz, S.4
Lin, G.5
Sun, Y.6
-
37
-
-
50849142558
-
Adult SVZ stem cells lie in a vascular niche: A quantitative analysis of niche cell-cell interactions
-
Q. Shen, Y. Wang, E. Kokovay, G. Lin, S.M. Chuang, and S.K. Goderie Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions Cell Stem Cell 3 2008 289 300
-
(2008)
Cell Stem Cell
, vol.3
, pp. 289-300
-
-
Shen, Q.1
Wang, Y.2
Kokovay, E.3
Lin, G.4
Chuang, S.M.5
Goderie, S.K.6
-
38
-
-
80052795862
-
Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
-
T.S. Zhu, M.A. Costello, C.E. Talsma, C.G. Flack, J.G. Crowley, and L.L. Hamm Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells Cancer Res 71 2011 6061 6072
-
(2011)
Cancer Res
, vol.71
, pp. 6061-6072
-
-
Zhu, T.S.1
Costello, M.A.2
Talsma, C.E.3
Flack, C.G.4
Crowley, J.G.5
Hamm, L.L.6
-
39
-
-
84861111256
-
The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: The role of the endothelial network
-
D.B. Gursel, N. Berry, and J.A. Boockvar The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: the role of the endothelial network Neurosurgery 70 2012 N19 N21
-
(2012)
Neurosurgery
, vol.70
-
-
Gursel, D.B.1
Berry, N.2
Boockvar, J.A.3
-
40
-
-
1642565876
-
Tumor hypoxia and malignant progression
-
P. Vaupel, A. Mayer, and M. Hockel Tumor hypoxia and malignant progression Methods Enzymol 381 2004 335 354
-
(2004)
Methods Enzymol
, vol.381
, pp. 335-354
-
-
Vaupel, P.1
Mayer, A.2
Hockel, M.3
-
41
-
-
57149119496
-
Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors
-
S.M. Evans, K.W. Jenkins, W.T. Jenkins, T. Dilling, K.D. Judy, and A. Schrlau Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors Radiat Res 170 2008 677 690
-
(2008)
Radiat Res
, vol.170
, pp. 677-690
-
-
Evans, S.M.1
Jenkins, K.W.2
Jenkins, W.T.3
Dilling, T.4
Judy, K.D.5
Schrlau, A.6
-
42
-
-
12144290194
-
Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding
-
S.M. Evans, K.D. Judy, I. Dunphy, W.T. Jenkins, P.T. Nelson, and R. Collins Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding Cancer Res 64 2004 1886 1892
-
(2004)
Cancer Res
, vol.64
, pp. 1886-1892
-
-
Evans, S.M.1
Judy, K.D.2
Dunphy, I.3
Jenkins, W.T.4
Nelson, P.T.5
Collins, R.6
-
43
-
-
77952330272
-
Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma
-
F. Pistollato, S. Abbadi, E. Rampazzo, L. Persano, A. Della Puppa, and C. Frasson Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma Stem Cells 28 2010 851 862
-
(2010)
Stem Cells
, vol.28
, pp. 851-862
-
-
Pistollato, F.1
Abbadi, S.2
Rampazzo, E.3
Persano, L.4
Della Puppa, A.5
Frasson, C.6
-
44
-
-
0037380791
-
Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ
-
K. Helczynska, A. Kronblad, A. Jogi, E. Nilsson, S. Beckman, and G. Landberg Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ Cancer Res 63 2003 1441 1444
-
(2003)
Cancer Res
, vol.63
, pp. 1441-1444
-
-
Helczynska, K.1
Kronblad, A.2
Jogi, A.3
Nilsson, E.4
Beckman, S.5
Landberg, G.6
-
45
-
-
0037076385
-
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
-
A. Jogi, I. Ora, H. Nilsson, A. Lindeheim, Y. Makino, and L. Poellinger Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype Proc Natl Acad Sci U S A 99 2002 7021 7026
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7021-7026
-
-
Jogi, A.1
Ora, I.2
Nilsson, H.3
Lindeheim, A.4
Makino, Y.5
Poellinger, L.6
-
46
-
-
33745328509
-
HIFing the brakes: Therapeutic opportunities for treatment of human malignancies
-
J.A. Garcia HIFing the brakes: therapeutic opportunities for treatment of human malignancies Sci STKE 2006 2006 pe25
-
(2006)
Sci STKE
, vol.2006
, pp. 25
-
-
Garcia, J.A.1
-
47
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
G.L. Wang, and G.L. Semenza Purification and characterization of hypoxia-inducible factor 1 J Biol Chem 270 1995 1230 1237
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
48
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
R.K. Bruick, and S.L. McKnight A conserved family of prolyl-4- hydroxylases that modify HIF Science 294 2001 1337 1340
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
50
-
-
33744457297
-
HIF-1: Hypoxia-inducible factor or dysoxia-inducible factor
-
M. Lopez-Lazaro HIF-1: hypoxia-inducible factor or dysoxia-inducible factor FASEB J 20 2006 828 832
-
(2006)
FASEB J
, vol.20
, pp. 828-832
-
-
Lopez-Lazaro, M.1
-
51
-
-
12544256565
-
Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
-
R.H. Xu, H. Pelicano, Y. Zhou, J.S. Carew, L. Feng, and K.N. Bhalla Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia Cancer Res 65 2005 613 621
-
(2005)
Cancer Res
, vol.65
, pp. 613-621
-
-
Xu, R.H.1
Pelicano, H.2
Zhou, Y.3
Carew, J.S.4
Feng, L.5
Bhalla, K.N.6
-
53
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
G.L. Semenza Targeting HIF-1 for cancer therapy Nat Rev Cancer 3 2003 721 732
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
54
-
-
41949112453
-
2 sensing: Only skin deep
-
2 sensing: only skin deep Cell 133 2008 206 208
-
(2008)
Cell
, vol.133
, pp. 206-208
-
-
Semenza, G.L.1
-
55
-
-
59849096400
-
Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma
-
F. Pistollato, H.L. Chen, B.R. Rood, H.Z. Zhang, D. D'Avella, and L. Denaro Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma Stem Cells 27 2009 7 17
-
(2009)
Stem Cells
, vol.27
, pp. 7-17
-
-
Pistollato, F.1
Chen, H.L.2
Rood, B.R.3
Zhang, H.Z.4
D'Avella, D.5
Denaro, L.6
-
56
-
-
67749142355
-
Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells
-
F. Pistollato, E. Rampazzo, S. Abbadi, A. Della Puppa, R. Scienza, and D. D'Avella Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells PLoS ONE 4 2009 e6206
-
(2009)
PLoS ONE
, vol.4
, pp. 6206
-
-
Pistollato, F.1
Rampazzo, E.2
Abbadi, S.3
Della Puppa, A.4
Scienza, R.5
D'Avella, D.6
-
57
-
-
34347226670
-
Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes
-
F. Pistollato, H.L. Chen, P.H. Schwartz, G. Basso, and D.M. Panchision Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes Mol Cell Neurosci 35 2007 424 435
-
(2007)
Mol Cell Neurosci
, vol.35
, pp. 424-435
-
-
Pistollato, F.1
Chen, H.L.2
Schwartz, P.H.3
Basso, G.4
Panchision, D.M.5
-
58
-
-
77956503727
-
Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres
-
E.E. Bar, A. Lin, V. Mahairaki, W. Matsui, and C.G. Eberhart Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres Am J Pathol 177 2010 1491 1502
-
(2010)
Am J Pathol
, vol.177
, pp. 1491-1502
-
-
Bar, E.E.1
Lin, A.2
Mahairaki, V.3
Matsui, W.4
Eberhart, C.G.5
-
59
-
-
27644561755
-
Hypoxia requires notch signaling to maintain the undifferentiated cell state
-
M.V. Gustafsson, X. Zheng, T. Pereira, K. Gradin, S. Jin, and J. Lundkvist Hypoxia requires notch signaling to maintain the undifferentiated cell state Dev Cell 9 2005 617 628
-
(2005)
Dev Cell
, vol.9
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
Gradin, K.4
Jin, S.5
Lundkvist, J.6
-
60
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
S.G. Piccirillo, B.A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, and G. Broggi Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells Nature 444 2006 761 765
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
Broggi, G.6
-
61
-
-
52049120148
-
Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: Correlation with time to progression and survival
-
A.M. Spence, M. Muzi, K.R. Swanson, F. O'Sullivan, J.K. Rockhill, and J.G. Rajendran Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival Clin Cancer Res 14 2008 2623 2630
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2623-2630
-
-
Spence, A.M.1
Muzi, M.2
Swanson, K.R.3
O'Sullivan, F.4
Rockhill, J.K.5
Rajendran, J.G.6
-
62
-
-
79959928027
-
Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids
-
J. Kolenda, S.S. Jensen, C. Aaberg-Jessen, K. Christensen, C. Andersen, and N. Brunner Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids J Neurooncol 103 2011 43 58
-
(2011)
J Neurooncol
, vol.103
, pp. 43-58
-
-
Kolenda, J.1
Jensen, S.S.2
Aaberg-Jessen, C.3
Christensen, K.4
Andersen, C.5
Brunner, N.6
-
63
-
-
65049084510
-
Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution
-
S.G. Piccirillo, R. Combi, L. Cajola, A. Patrizi, S. Redaelli, and A. Bentivegna Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution Oncogene 28 2009 1807 1811
-
(2009)
Oncogene
, vol.28
, pp. 1807-1811
-
-
Piccirillo, S.G.1
Combi, R.2
Cajola, L.3
Patrizi, A.4
Redaelli, S.5
Bentivegna, A.6
-
64
-
-
79953865922
-
Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma
-
M. Tafani, M. Di Vito, A. Frati, L. Pellegrini, E. De Santis, and G. Sette Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma J Neuroinflammation 8 2011 32
-
(2011)
J Neuroinflammation
, vol.8
, pp. 32
-
-
Tafani, M.1
Di Vito, M.2
Frati, A.3
Pellegrini, L.4
De Santis, E.5
Sette, G.6
-
65
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
S. Bao, Q. Wu, R.E. McLendon, Y. Hao, Q. Shi, and A.B. Hjelmeland Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 444 2006 756 760
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
-
66
-
-
48649104080
-
Temozolomide preferentially depletes cancer stem cells in glioblastoma
-
D. Beier, S. Rohrl, D.R. Pillai, S. Schwarz, L.A. Kunz-Schughart, and P. Leukel Temozolomide preferentially depletes cancer stem cells in glioblastoma Cancer Res 68 2008 5706 5715
-
(2008)
Cancer Res
, vol.68
, pp. 5706-5715
-
-
Beier, D.1
Rohrl, S.2
Pillai, D.R.3
Schwarz, S.4
Kunz-Schughart, L.A.5
Leukel, P.6
-
67
-
-
33846237601
-
HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
-
V. Clement, P. Sanchez, N. de Tribolet, I. Radovanovic, and A. Ruiz i Altaba HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity Curr Biol 17 2007 165 172
-
(2007)
Curr Biol
, vol.17
, pp. 165-172
-
-
Clement, V.1
Sanchez, P.2
De Tribolet, N.3
Radovanovic, I.4
Ruiz Altaba I, A.5
-
68
-
-
58149166478
-
Characterization of a side population of astrocytoma cells in response to temozolomide
-
C. Chua, N. Zaiden, K.H. Chong, S.J. See, M.C. Wong, and B.T. Ang Characterization of a side population of astrocytoma cells in response to temozolomide J Neurosurg 109 2008 856 866
-
(2008)
J Neurosurg
, vol.109
, pp. 856-866
-
-
Chua, C.1
Zaiden, N.2
Chong, K.H.3
See, S.J.4
Wong, M.C.5
Ang, B.T.6
-
69
-
-
33845972599
-
Concise review: Bone morphogenetic protein pleiotropism in neural stem cells and their derivatives-alternative pathways, convergent signals
-
H.L. Chen, and D.M. Panchision Concise review: bone morphogenetic protein pleiotropism in neural stem cells and their derivatives-alternative pathways, convergent signals Stem Cells 25 2007 63 68
-
(2007)
Stem Cells
, vol.25
, pp. 63-68
-
-
Chen, H.L.1
Panchision, D.M.2
-
70
-
-
77954368572
-
Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells
-
S.R. Chirasani, A. Sternjak, P. Wend, S. Momma, B. Campos, and I.M. Herrmann Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells Brain 133 2010 1961 1972
-
(2010)
Brain
, vol.133
, pp. 1961-1972
-
-
Chirasani, S.R.1
Sternjak, A.2
Wend, P.3
Momma, S.4
Campos, B.5
Herrmann, I.M.6
-
71
-
-
84866116474
-
A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells
-
C.M. Tate, R. Pallini, L. Ricci-Vitiani, M. Dowless, T. Shiyanova, and G.Q. D'Alessandris A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells Cell Death Differ 2012
-
(2012)
Cell Death Differ
-
-
Tate, C.M.1
Pallini, R.2
Ricci-Vitiani, L.3
Dowless, M.4
Shiyanova, T.5
D'Alessandris, G.Q.6
-
72
-
-
37349067098
-
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
-
J. Lee, M.J. Son, K. Woolard, N.M. Donin, A. Li, and C.H. Cheng Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells Cancer Cell 13 2008 69 80
-
(2008)
Cancer Cell
, vol.13
, pp. 69-80
-
-
Lee, J.1
Son, M.J.2
Woolard, K.3
Donin, N.M.4
Li, A.5
Cheng, C.H.6
-
73
-
-
85028115908
-
Beta-catenin overexpression in malignant glioma and its role in proliferation and apoptosis in glioblastma cells
-
X. Liu, L. Wang, S. Zhao, X. Ji, Y. Luo, and F. Ling Beta-catenin overexpression in malignant glioma and its role in proliferation and apoptosis in glioblastma cells Med Oncol 28 2010 608 614
-
(2010)
Med Oncol
, vol.28
, pp. 608-614
-
-
Liu, X.1
Wang, L.2
Zhao, S.3
Ji, X.4
Luo, Y.5
Ling, F.6
-
74
-
-
62549151288
-
Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth
-
P. Pu, Z. Zhang, C. Kang, R. Jiang, Z. Jia, and G. Wang Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth Cancer Gene Ther 16 2009 351 361
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 351-361
-
-
Pu, P.1
Zhang, Z.2
Kang, C.3
Jiang, R.4
Jia, Z.5
Wang, G.6
-
75
-
-
79952823258
-
Epigenetic regulation of wnt pathway antagonists in human glioblastoma multiforme
-
G. Foltz, J.G. Yoon, H. Lee, L. Ma, Q. Tian, and L. Hood Epigenetic regulation of wnt pathway antagonists in human glioblastoma multiforme Genes Cancer 1 2011 81 90
-
(2011)
Genes Cancer
, vol.1
, pp. 81-90
-
-
Foltz, G.1
Yoon, J.G.2
Lee, H.3
Ma, L.4
Tian, Q.5
Hood, L.6
-
76
-
-
85047699343
-
Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA
-
J. Shou, F. Ali-Osman, A.S. Multani, S. Pathak, P. Fedi, and K.S. Srivenugopal Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA Oncogene 21 2002 878 889
-
(2002)
Oncogene
, vol.21
, pp. 878-889
-
-
Shou, J.1
Ali-Osman, F.2
Multani, A.S.3
Pathak, S.4
Fedi, P.5
Srivenugopal, K.S.6
-
77
-
-
54549095950
-
P53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
-
H. Zheng, H. Ying, H. Yan, A.C. Kimmelman, D.J. Hiller, and A.J. Chen p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation Nature 455 2008 1129 1133
-
(2008)
Nature
, vol.455
, pp. 1129-1133
-
-
Zheng, H.1
Ying, H.2
Yan, H.3
Kimmelman, A.C.4
Hiller, D.J.5
Chen, A.J.6
-
78
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
A.M. Bleau, D. Hambardzumyan, T. Ozawa, E.I. Fomchenko, J.T. Huse, and C.W. Brennan PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells Cell Stem Cell 4 2009 226 235
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
-
79
-
-
84855451538
-
Antitumor activity of NVP-BKM120-a selective pan class i PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells
-
D. Koul, J. Fu, R. Shen, T.A. LaFortune, S. Wang, and N. Tiao Antitumor activity of NVP-BKM120-a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells Clin Cancer Res 18 2012 184 195
-
(2012)
Clin Cancer Res
, vol.18
, pp. 184-195
-
-
Koul, D.1
Fu, J.2
Shen, R.3
Lafortune, T.A.4
Wang, S.5
Tiao, N.6
-
80
-
-
77956004085
-
Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma
-
D. Koul, R. Shen, Y.W. Kim, Y. Kondo, Y. Lu, and J. Bankson Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma Neuro Oncol 12 2010 559 569
-
(2010)
Neuro Oncol
, vol.12
, pp. 559-569
-
-
Koul, D.1
Shen, R.2
Kim, Y.W.3
Kondo, Y.4
Lu, Y.5
Bankson, J.6
-
81
-
-
58049198191
-
Brain cancer stem cells display preferential sensitivity to Akt inhibition
-
C.E. Eyler, W.C. Foo, K.M. LaFiura, R.E. McLendon, A.B. Hjelmeland, and J.N. Rich Brain cancer stem cells display preferential sensitivity to Akt inhibition Stem Cells 26 2008 3027 3036
-
(2008)
Stem Cells
, vol.26
, pp. 3027-3036
-
-
Eyler, C.E.1
Foo, W.C.2
Lafiura, K.M.3
McLendon, R.E.4
Hjelmeland, A.B.5
Rich, J.N.6
-
82
-
-
23844457178
-
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo
-
H. Momota, E. Nerio, and E.C. Holland Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo Cancer Res 65 2005 7429 7435
-
(2005)
Cancer Res
, vol.65
, pp. 7429-7435
-
-
Momota, H.1
Nerio, E.2
Holland, E.C.3
-
83
-
-
33746077733
-
Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells
-
L. de la Pena, W.E. Burgan, D.J. Carter, M.G. Hollingshead, M. Satyamitra, and K. Camphausen Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells Mol Cancer Ther 5 2006 1504 1510
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1504-1510
-
-
De La Pena, L.1
Burgan, W.E.2
Carter, D.J.3
Hollingshead, M.G.4
Satyamitra, M.5
Camphausen, K.6
-
84
-
-
79251575938
-
Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma
-
K.L. Pitter, C.J. Galban, S. Galban, O.S. Tehrani, F. Li, and N. Charles Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma PLoS One 6 2011 e14545
-
(2011)
PLoS One
, vol.6
, pp. 14545
-
-
Pitter, K.L.1
Galban, C.J.2
Galban, S.3
Tehrani, O.S.4
Li, F.5
Charles, N.6
-
85
-
-
84862895654
-
Current clinical development of PI3K pathway inhibitors in glioblastoma
-
P.Y. Wen, E.Q. Lee, D.A. Reardon, K.L. Ligon, and W.K. Alfred Yung Current clinical development of PI3K pathway inhibitors in glioblastoma Neuro Oncol 14 2012 819 829
-
(2012)
Neuro Oncol
, vol.14
, pp. 819-829
-
-
Wen, P.Y.1
Lee, E.Q.2
Reardon, D.A.3
Ligon, K.L.4
Alfred Yung, W.K.5
-
86
-
-
79959996485
-
Pathway inhibition: Emerging molecular targets for treating glioblastoma
-
W. Wick, M. Weller, M. Weiler, T. Batchelor, A.W. Yung, and M. Platten Pathway inhibition: emerging molecular targets for treating glioblastoma Neuro Oncol 13 2011 566 579
-
(2011)
Neuro Oncol
, vol.13
, pp. 566-579
-
-
Wick, W.1
Weller, M.2
Weiler, M.3
Batchelor, T.4
Yung, A.W.5
Platten, M.6
-
87
-
-
60849104091
-
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells
-
G.L. Gallia, B.M. Tyler, C.L. Hann, I.M. Siu, V.L. Giranda, and A.L. Vescovi Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells Mol Cancer Ther 8 2009 386 393
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 386-393
-
-
Gallia, G.L.1
Tyler, B.M.2
Hann, C.L.3
Siu, I.M.4
Giranda, V.L.5
Vescovi, A.L.6
-
88
-
-
21044431575
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
-
S.M. Chang, P. Wen, T. Cloughesy, H. Greenberg, D. Schiff, and C. Conrad Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme Invest New Drugs 23 2005 357 361
-
(2005)
Invest New Drugs
, vol.23
, pp. 357-361
-
-
Chang, S.M.1
Wen, P.2
Cloughesy, T.3
Greenberg, H.4
Schiff, D.5
Conrad, C.6
-
89
-
-
23944453425
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A North Central Cancer Treatment Group Study
-
E. Galanis, J.C. Buckner, M.J. Maurer, J.I. Kreisberg, K. Ballman, and J. Boni Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study J Clin Oncol 23 2005 5294 5304
-
(2005)
J Clin Oncol
, vol.23
, pp. 5294-5304
-
-
Galanis, E.1
Buckner, J.C.2
Maurer, M.J.3
Kreisberg, J.I.4
Ballman, K.5
Boni, J.6
-
90
-
-
75149186046
-
Chemotherapy for glioblastoma: Current treatment and future perspectives for cytotoxic and targeted agents
-
G. Minniti, R. Muni, G. Lanzetta, P. Marchetti, and R.M. Enrici Chemotherapy for glioblastoma: current treatment and future perspectives for cytotoxic and targeted agents Anticancer Res 29 2009 5171 5184
-
(2009)
Anticancer Res
, vol.29
, pp. 5171-5184
-
-
Minniti, G.1
Muni, R.2
Lanzetta, G.3
Marchetti, P.4
Enrici, R.M.5
-
91
-
-
70449457461
-
Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility
-
N. Gulati, M. Karsy, L. Albert, R. Murali, and M. Jhanwar-Uniyal Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility Int J Oncol 35 2009 731 740
-
(2009)
Int J Oncol
, vol.35
, pp. 731-740
-
-
Gulati, N.1
Karsy, M.2
Albert, L.3
Murali, R.4
Jhanwar-Uniyal, M.5
-
92
-
-
79953052206
-
Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide
-
G. Prasad, T. Sottero, X. Yang, S. Mueller, C.D. James, and W.A. Weiss Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide Neuro Oncol 13 2011 384 392
-
(2011)
Neuro Oncol
, vol.13
, pp. 384-392
-
-
Prasad, G.1
Sottero, T.2
Yang, X.3
Mueller, S.4
James, C.D.5
Weiss, W.A.6
-
93
-
-
78651385352
-
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models
-
T. Bagci-Onder, H. Wakimoto, M. Anderegg, C. Cameron, and K. Shah A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell-delivered TRAIL in experimental glioma models Cancer Res 71 2011 154 163
-
(2011)
Cancer Res
, vol.71
, pp. 154-163
-
-
Bagci-Onder, T.1
Wakimoto, H.2
Anderegg, M.3
Cameron, C.4
Shah, K.5
-
94
-
-
42249090359
-
Characterization of structurally distinct, isoform-selective phosphoinositide 3′-kinase inhibitors in combination with radiation in the treatment of glioblastoma
-
J.S. Chen, L.J. Zhou, M. Entin-Meer, X. Yang, M. Donker, and Z.A. Knight Characterization of structurally distinct, isoform-selective phosphoinositide 3′-kinase inhibitors in combination with radiation in the treatment of glioblastoma Mol Cancer Ther 7 2008 841 850
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 841-850
-
-
Chen, J.S.1
Zhou, L.J.2
Entin-Meer, M.3
Yang, X.4
Donker, M.5
Knight, Z.A.6
-
95
-
-
70349974841
-
The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair
-
M.A. Westhoff, J.A. Kandenwein, S. Karl, S.H. Vellanki, V. Braun, and A. Eramo The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair Oncogene 28 2009 3586 3596
-
(2009)
Oncogene
, vol.28
, pp. 3586-3596
-
-
Westhoff, M.A.1
Kandenwein, J.A.2
Karl, S.3
Vellanki, S.H.4
Braun, V.5
Eramo, A.6
-
96
-
-
84555187723
-
Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors
-
Q.W. Fan, and W.A. Weiss Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors Methods Mol Biol 821 2012 349 359
-
(2012)
Methods Mol Biol
, vol.821
, pp. 349-359
-
-
Fan, Q.W.1
Weiss, W.A.2
-
97
-
-
79955681509
-
Autophagy and Akt promote survival in glioma
-
Q.W. Fan, and W.A. Weiss Autophagy and Akt promote survival in glioma Autophagy 7 2011 536 538
-
(2011)
Autophagy
, vol.7
, pp. 536-538
-
-
Fan, Q.W.1
Weiss, W.A.2
-
98
-
-
78649831949
-
Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells
-
J. Sunayama, K. Matsuda, A. Sato, K. Tachibana, K. Suzuki, and Y. Narita Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells Stem Cells 28 2010 1930 1939
-
(2010)
Stem Cells
, vol.28
, pp. 1930-1939
-
-
Sunayama, J.1
Matsuda, K.2
Sato, A.3
Tachibana, K.4
Suzuki, K.5
Narita, Y.6
-
99
-
-
80052020964
-
FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity
-
J. Sunayama, A. Sato, K. Matsuda, K. Tachibana, E. Watanabe, and S. Seino FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity Stem Cells 29 2011 1327 1337
-
(2011)
Stem Cells
, vol.29
, pp. 1327-1337
-
-
Sunayama, J.1
Sato, A.2
Matsuda, K.3
Tachibana, K.4
Watanabe, E.5
Seino, S.6
-
100
-
-
84859445000
-
Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy
-
G.L. Semenza Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy Trends Pharmacol Sci 33 2012 207 214
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 207-214
-
-
Semenza, G.L.1
-
101
-
-
84862818535
-
Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
-
Y. Xia, H.K. Choi, and K. Lee Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors Eur J Med Chem 49 2012 24 40
-
(2012)
Eur J Med Chem
, vol.49
, pp. 24-40
-
-
Xia, Y.1
Choi, H.K.2
Lee, K.3
-
102
-
-
85046979809
-
Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2
-
S. Coma, A. Shimizu, and M. Klagsbrun Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2 Cell Adh Migr 5 2011 266 275
-
(2011)
Cell Adh Migr
, vol.5
, pp. 266-275
-
-
Coma, S.1
Shimizu, A.2
Klagsbrun, M.3
-
103
-
-
84861774808
-
CXCR4-positive subset of glioma is enriched for cancer stem cells
-
X. Zheng, Q. Xie, S. Li, and W. Zhang CXCR4-positive subset of glioma is enriched for cancer stem cells Oncol Res 19 2012 555 561
-
(2012)
Oncol Res
, vol.19
, pp. 555-561
-
-
Zheng, X.1
Xie, Q.2
Li, S.3
Zhang, W.4
-
104
-
-
79958107497
-
Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas
-
D. Tseng, D.A. Vasquez-Medrano, and J.M. Brown Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas Br J Cancer 104 2011 1805 1809
-
(2011)
Br J Cancer
, vol.104
, pp. 1805-1809
-
-
Tseng, D.1
Vasquez-Medrano, D.A.2
Brown, J.M.3
-
105
-
-
77949697909
-
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
-
M. Kioi, H. Vogel, G. Schultz, R.M. Hoffman, G.R. Harsh, and J.M. Brown Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice J Clin Invest 120 2010 694 705
-
(2010)
J Clin Invest
, vol.120
, pp. 694-705
-
-
Kioi, M.1
Vogel, H.2
Schultz, G.3
Hoffman, R.M.4
Harsh, G.R.5
Brown, J.M.6
-
106
-
-
84859708992
-
Is there a world beyond bevacizumab in targeting angiogenesis in glioblastoma
-
K. Seystahl, and M. Weller Is there a world beyond bevacizumab in targeting angiogenesis in glioblastoma Expert Opin Investig Drugs 21 2012 605 617
-
(2012)
Expert Opin Investig Drugs
, vol.21
, pp. 605-617
-
-
Seystahl, K.1
Weller, M.2
-
107
-
-
77954720781
-
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
-
T.T. Batchelor, D.G. Duda, E. di Tomaso, M. Ancukiewicz, S.R. Plotkin, and E. Gerstner Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma J Clin Oncol 28 2010 2817 2823
-
(2010)
J Clin Oncol
, vol.28
, pp. 2817-2823
-
-
Batchelor, T.T.1
Duda, D.G.2
Di Tomaso, E.3
Ancukiewicz, M.4
Plotkin, S.R.5
Gerstner, E.6
-
108
-
-
77954730533
-
Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib
-
E.R. Gerstner, P.J. Chen, P.Y. Wen, R.K. Jain, T.T. Batchelor, and G. Sorensen Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib Neuro Oncol 12 2010 466 472
-
(2010)
Neuro Oncol
, vol.12
, pp. 466-472
-
-
Gerstner, E.R.1
Chen, P.J.2
Wen, P.Y.3
Jain, R.K.4
Batchelor, T.T.5
Sorensen, G.6
-
109
-
-
78149478057
-
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib
-
M. Chahal, Y. Xu, D. Lesniak, K. Graham, K. Famulski, and J.G. Christensen MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib Neuro Oncol 12 2010 822 833
-
(2010)
Neuro Oncol
, vol.12
, pp. 822-833
-
-
Chahal, M.1
Xu, Y.2
Lesniak, D.3
Graham, K.4
Famulski, K.5
Christensen, J.G.6
-
110
-
-
84866364645
-
A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma
-
E. Pan, D. Yu, B. Yue, L. Potthast, S. Chowdhary, and P. Smith A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma J Neurooncol 110 2012 111 118
-
(2012)
J Neurooncol
, vol.110
, pp. 111-118
-
-
Pan, E.1
Yu, D.2
Yue, B.3
Potthast, L.4
Chowdhary, S.5
Smith, P.6
-
111
-
-
79959795987
-
Phase II study of sunitinib malate in patients with recurrent high-grade glioma
-
B. Neyns, J. Sadones, C. Chaskis, M. Dujardin, H. Everaert, and S. Lv Phase II study of sunitinib malate in patients with recurrent high-grade glioma J Neurooncol 103 2011 491 501
-
(2011)
J Neurooncol
, vol.103
, pp. 491-501
-
-
Neyns, B.1
Sadones, J.2
Chaskis, C.3
Dujardin, M.4
Everaert, H.5
Lv, S.6
-
112
-
-
82955232920
-
Phase i study of sunitinib and irinotecan for patients with recurrent malignant glioma
-
D.A. Reardon, J.J. Vredenburgh, A. Coan, A. Desjardins, K.B. Peters, and S. Gururangan Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma J Neurooncol 105 2011 621 627
-
(2011)
J Neurooncol
, vol.105
, pp. 621-627
-
-
Reardon, D.A.1
Vredenburgh, J.J.2
Coan, A.3
Desjardins, A.4
Peters, K.B.5
Gururangan, S.6
-
113
-
-
78149258374
-
Phase i study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma
-
A. Broniscer, J.N. Baker, M. Tagen, A. Onar-Thomas, R.J. Gilbertson, and A.M. Davidoff Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma J Clin Oncol 28 2010 4762 4768
-
(2010)
J Clin Oncol
, vol.28
, pp. 4762-4768
-
-
Broniscer, A.1
Baker, J.N.2
Tagen, M.3
Onar-Thomas, A.4
Gilbertson, R.J.5
Davidoff, A.M.6
-
114
-
-
23044500424
-
Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma
-
V. Damiano, D. Melisi, C. Bianco, D. Raben, R. Caputo, and G. Fontanini Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma Clin Cancer Res 11 2005 5639 5644
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5639-5644
-
-
Damiano, V.1
Melisi, D.2
Bianco, C.3
Raben, D.4
Caputo, R.5
Fontanini, G.6
-
115
-
-
77955922743
-
Phase i study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma
-
J. Drappatz, A.D. Norden, E.T. Wong, L.M. Doherty, D.C. Lafrankie, and A. Ciampa Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma Int J Radiat Oncol Biol Phys 78 2010 85 90
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
, pp. 85-90
-
-
Drappatz, J.1
Norden, A.D.2
Wong, E.T.3
Doherty, L.M.4
Lafrankie, D.C.5
Ciampa, A.6
|