Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2

Cell Adhesion and Migration

Volumn 5, Issue 3, 2011, Pages 266-275

  Coma, Silvia ^a   Shimizu, Akio ^a   Klagsbrun, Michael ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Angiogenesis; Endothelial cells; Hypoxia; Migration; Neuropilin 2; Semaphorin 3F; Tumor; VEGF

Indexed keywords

DEFEROXAMINE; F ACTIN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPILIN 2; PROTEIN P42; PROTEIN P44; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SEMAPHORIN 3F; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; HIF1A PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN; SEMA3F PROTEIN, HUMAN; SMALL INTERFERING RNA; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DEPOLYMERIZATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPOXIA; IN VIVO STUDY; METASTASIS; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR GROWTH; CELL HYPOXIA; CELL LINE; CELL MOTION; DRUG EFFECT; GENETICS; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

CELL HYPOXIA; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; DEFEROXAMINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; NEUROPILIN-2; RNA, SMALL INTERFERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 85046979809     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.5.3.16294     Document Type: Article

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