Gene expression-based classification of malignant gliomas correlates better with survival than histological classification

Cancer Research

Volumn 63, Issue 7, 2003, Pages 1602-1607

  Nutt, Catherine L ^a   Mani, D R ^b   Betensky, Rebecca A ^e   Tamayo, Pablo ^b   Cairncross, J Gregory ^g   Ladd, Christine ^b   Pohl, Ute ^a   Hartmann, Christian ^a   McLaughlin, Margaret E ^c   Batchelor, Tracy T ^a   Black, Peter M ^c   Von Deimling, Andreas ^h   Pomeroy, Scott L ^d   Golub, Todd R ^b,f   Louis, David N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF WESTERN ONTARIO   (Canada)

^h HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ARTICLE; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER SURVIVAL; DNA MICROARRAY; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA; HISTOLOGY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LEARNING; OLIGODENDROGLIOMA; PREDICTION; PRIORITY JOURNAL; VALIDATION PROCESS;

BRAIN NEOPLASMS; GENE EXPRESSION PROFILING; GLIOMA; HUMANS; MODELS, GENETIC; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REPRODUCIBILITY OF RESULTS; SURVIVAL RATE;

EID: 0037381008     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Kleihues, P., and Cavenee, W. K. World Health Organization Classification of Tumours of the Nervous System. Lyon, France: WHO/IARC, 2000.
2. Cairncross, J. G., and Macdonald, D. R. Successful chemotherapy for malignant oligodendroglioma. Ann. Neurol., 23: 360-364, 1988.
3. Cairncross, J. G., Ueki, K., Zlatescu, M. C., Lisle, D. K., Finkelstein, D. M., Hammond, R. R., Silver, J. S., Stark, P. C., Macdonald, D. R., Ino, Y., Ramsay, D. A., and Louis, D. N. Specific chromosomal losses predict chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J. Natl. Cancer. Inst. (Bethesda), 90: 1473-1479, 1998.
4. Burger, P. C. What is an oligodendroglioma? Brain Pathol., 12: 257-259, 2002.
5. Ironside, J. W., Moss, T. H., Louis, D. N., Lowe, J. S., and Weller, R. O. Diagnostic Pathology of Nervous System Tumours. London: Churchill Livingstone, 2002.
6. Burger, P. C., Scheithauer, B. W., and Vogel, F. S. Surgical Pathology of the Nervous System and its Coverings, Ed. 4, London: Churchill Livingstone, 2002.
7. Louis, D. N., Holland, E. C., and Cairncross, J. G. Glioma classification: a molecular reappraisal. Am. J. Pathol., 159: 779-786, 2001.
8. Coons, S. W., Johnson, P. C., Scheithauer, B. W., Yates, A. J., and Pearl, D. K. Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas. Cancer (Phila.), 79: 1381-1393, 1997.
9. Giannini, C., Scheithauer, B. W., Weaver, A. L., Burger, P. C., Kros, J. M., Mork, S., Graeber, M. B., Bauserman, S., Buckner, J. C., Burton, J., Riepe, R., Tazelaar, H. D., Nascimento, A. G., Crotty, T., Keeney, G. L., Pernicone, P., and Altermatt, H. Oligodendrogliomas: reproducibility and prognostic value of histologic diagnosis and grading. J. Neuropathol. Exp. Neurol., 60: 248-262, 2001.
10. Sasaki, H., Zlatescu, M. C., Betensky, R. A., Johnk, L., Cutone, A., Cairncross, J. G., and Louis, D. N. Histopathological-molecular genetic correlations in referral pathologist-diagnosed low-grade "oligodendroglioma." J. Neuropathol. Exp. Neurol., 61: 58-63, 2002.
11. Burger, P. C., Minn, A. Y., Smith, J. S., Borell, T. J., Jedlicka, A. E., Huntley, B. K., Goldthwaite, P. T., Jenkins, R. B., and Feuerstein, B. G. Losses of chromosomal arms 1p and 19q in the diagnosis of oligodendroglioma. A study of paraffin-embedded sections. Mod. Pathol., 14: 842-853, 2001.
12. Lu, Q. R., Park, J. K., Noll, E., Chan, J. A., Alberta, J., Yuk, D., Alzamora, M. G., Louis, D. N., Stiles, C. D., Rowitch, D. H., and Black, P. M. Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors. Proc. Natl. Acad. Sci. USA, 98: 10851-10856, 2001.
13. Popko, B., Pearl, D. K., Walker, D. M., Comas, T. C., Baerwald, K. D., Burger, P. C., Scheithauer, B. W., and Yates, A. J. Molecular markers that identify human astrocytomas and oligodendrogliomas. J. Neuropathol. Exp. Neurol., 61: 329-338, 2002.
14. Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., Bloomfield, C. D., and Lander, E. S. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science (Wash. DC), 286: 531-537, 1999.
15. Bhattacharjee, A., Richards, W. G., Staunton, J., Li, C., Monti, S., Vasa, P., Ladd, C., Beheshti, J., Bucno, R., Gillette, M., Loda, M., Weber, G., Mark, E. J., Lander, E. S., Wong, W., Johnson, B. E., Golub, T. R., Sugarbaker, D. J., and Meyerson, M. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl. Acad. Sci. USA, 98: 13790-13795, 2001.
16. Pomcroy, S. L., Tamayo, P., Gaasenbeek, M., Sturla, L. M., Angelo, M., McLaughlin, M. E., Kim, J. Y. H., Goumnerova, L. C., Black, P. M., Lau, C., Allen, J. C., Zagzag, D., Olson, J. M., Curran, T., Wetmore, C., Biegel, J. A., Poggio, T., Mukherjee, S., Rifkin, R., Califano, A., Stolovitzky, G., Louis, D. N., Mesirov, J. P., Lander, E. S., and Golub, T. R. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature (Lond.), 415: 436-442, 2002.
17. Boettner, B., and Van Aelst, L. The role of Rho GTPases in disease development. Gene, 286: 155-174, 2002.
18. Ridley, A. J. Rho GTPases and cell migration. J. Cell Sci., 114: 2713-2722, 2001.
19. Clemens, M. J., and Bommer, U-A. Translational control: the cancer connection. Int. J. Biochem. Cell Biol., 31: 1-23, 1999.