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Volumn 10, Issue 2, 2013, Pages 650-663

Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures

Author keywords

acyclovir; BCRP; cornea; expression profiling; eye; gene expression; OAT2; OCT3; open array; protein expression; retina; transporters

Indexed keywords

ABC TRANSPORTER; ACICLOVIR; BREAST CANCER RESISTANCE PROTEIN; CELL NUCLEUS RECEPTOR; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; RNA; TRANSCRIPTION FACTOR; VISUAL PIGMENT;

EID: 84873336516     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300429e     Document Type: Article
Times cited : (53)

References (103)
  • 2
    • 13944264268 scopus 로고    scopus 로고
    • Permeability of retinal pigment epithelium: Effects of permeant molecular weight and lipophilicity
    • DOI 10.1167/iovs.04-1051
    • Pitkanen, L.; Ranta, V. P.; Moilanen, H.; Urtti, A. Permeability of retinal pigment epithelium: effects of permeant molecular weight and lipophilicity Invest. Ophthalmol. Visual Sci. 2005, 46, 641-646 (Pubitemid 40270347)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.2 , pp. 641-646
    • Pitkanen, L.1    Ranta, V.-P.2    Moilanen, H.3    Urtti, A.4
  • 4
    • 0031772606 scopus 로고    scopus 로고
    • Permeability of cornea, sclera, and conjunctiva: A literature analysis for drug delivery to the eye
    • Prausnitz, M. R.; Noonan, J. S. Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye J. Pharm. Sci. 1998, 87, 1479-1488
    • (1998) J. Pharm. Sci. , vol.87 , pp. 1479-1488
    • Prausnitz, M.R.1    Noonan, J.S.2
  • 7
    • 77955796725 scopus 로고    scopus 로고
    • The role of blood-ocular barrier transporters in retinal drug disposition: An overview
    • Tomi, M.; Hosoya, K. The role of blood-ocular barrier transporters in retinal drug disposition: an overview Expert Opin. Drug Metab. Toxicol. 2010, 6, 1111-1124
    • (2010) Expert Opin. Drug Metab. Toxicol. , vol.6 , pp. 1111-1124
    • Tomi, M.1    Hosoya, K.2
  • 8
    • 1242340323 scopus 로고    scopus 로고
    • The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins
    • DOI 10.1007/s00424-003-1192-y, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Hediger, M. A.; Romero, M. F.; Peng, J. B.; Rolfs, A.; Takanaga, H.; Bruford, E. A. The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction Pfluegers Arch. 2004, 447, 465-468 (Pubitemid 38241432)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 465-468
    • Hediger, M.A.1    Romero, M.F.2    Peng, J.-B.3    Rolfs, A.4    Takanaga, H.5    Bruford, E.A.6
  • 9
    • 84879211757 scopus 로고    scopus 로고
    • ABC transporters, mechanisms and biology: An overview
    • Holland, I. B. ABC transporters, mechanisms and biology: an overview Essays Biochem. 2011, 50, 1-17
    • (2011) Essays Biochem. , vol.50 , pp. 1-17
    • Holland, I.B.1
  • 10
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • DOI 10.1146/annurev.biochem.71.102301.093055
    • Borst, P.; Elferink, R. O. Mammalian ABC transporters in health and disease Annu. Rev. Biochem. 2002, 71, 537-592 (Pubitemid 34800230)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 537-592
    • Borst, P.1    Oude Elferink, R.2
  • 11
    • 0030728254 scopus 로고    scopus 로고
    • Molecular properties of hepatic uptake systems for bile acids and organic anions
    • DOI 10.1007/s002329900290
    • Hagenbuch, B. Molecular properties of hepatic uptake systems for bile acids and organic anions J. Membr. Biol. 1997, 160, 1-8 (Pubitemid 27491717)
    • (1997) Journal of Membrane Biology , vol.160 , Issue.1 , pp. 1-8
    • Hagenbuch, B.1
  • 12
    • 0036916855 scopus 로고    scopus 로고
    • Transport of xenobiotics across the blood-brain barrier
    • Hagenbuch, B.; Gao, B.; Meier, P. J. Transport of xenobiotics across the blood-brain barrier News Physiol. Sci. 2002, 17, 231-234 (Pubitemid 36015530)
    • (2002) News in Physiological Sciences , vol.17 , Issue.DEC. , pp. 231-234
    • Hagenbuch, B.1    Gao, B.2    Meier, P.J.3
  • 13
    • 72849130145 scopus 로고    scopus 로고
    • Drug uptake systems in liver and kidney: A historic perspective
    • Hagenbuch, B. Drug uptake systems in liver and kidney: a historic perspective Clin. Pharmacol. Ther. 2010, 87, 39-47
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 39-47
    • Hagenbuch, B.1
  • 14
    • 0031893146 scopus 로고    scopus 로고
    • Organic cation transporters in intestine, kidney, liver, and brain
    • DOI 10.1146/annurev.physiol.60.1.243
    • Koepsell, H. Organic cation transporters in intestine, kidney, liver, and brain Annu. Rev. Physiol. 1998, 60, 243-266 (Pubitemid 28157873)
    • (1998) Annual Review of Physiology , vol.60 , pp. 243-266
    • Koepsell, H.1
  • 15
    • 34547208011 scopus 로고    scopus 로고
    • Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues
    • DOI 10.1038/ncpneph0558, PII NCPNEPH0558
    • Nigam, S. K.; Bush, K. T.; Bhatnagar, V. Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues Nat. Clin. Pract. Nephrol. 2007, 3, 443-448 (Pubitemid 47123587)
    • (2007) Nature Clinical Practice Nephrology , vol.3 , Issue.8 , pp. 443-448
    • Nigam, S.K.1    Bush, K.T.2    Bhatnagar, V.3
  • 16
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • DOI 10.1016/S0169-409X(02)00169-2, PII S0169409X02001692
    • Schinkel, A. H.; Jonker, J. W. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview Adv. Drug Delivery Rev. 2003, 55, 3-29 (Pubitemid 36078452)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.1 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 17
    • 0034880349 scopus 로고    scopus 로고
    • The organic anion transporter family: From physiology to ontogeny and the clinic
    • Sweet, D. H.; Bush, K. T.; Nigam, S. K. The organic anion transporter family: from physiology to ontogeny and the clinic Am. J. Physiol. 2001, 281, F197-F205
    • (2001) Am. J. Physiol. , vol.281
    • Sweet, D.H.1    Bush, K.T.2    Nigam, S.K.3
  • 18
    • 1442302327 scopus 로고    scopus 로고
    • The role of organic ion transporters in drug disposition: An update
    • DOI 10.2174/1389200043489207
    • You, G. The role of organic ion transporters in drug disposition: an update Curr. Drug Metab. 2004, 5, 55-62 (Pubitemid 38279407)
    • (2004) Current Drug Metabolism , vol.5 , Issue.1 , pp. 55-62
    • You, G.1
  • 19
    • 80053558294 scopus 로고    scopus 로고
    • The ABC of the blood-brain barrier - Regulation of drug efflux pumps
    • Mahringer, A.; Ott, M.; Reimold, I.; Reichel, V.; Fricker, G. The ABC of the blood-brain barrier-regulation of drug efflux pumps Curr. Pharm. Des. 2011, 17, 2762-2770
    • (2011) Curr. Pharm. Des. , vol.17 , pp. 2762-2770
    • Mahringer, A.1    Ott, M.2    Reimold, I.3    Reichel, V.4    Fricker, G.5
  • 20
    • 0026284717 scopus 로고
    • Advances in cell biology of blood-brain barrier transport
    • Pardridge, W. M. Advances in cell biology of blood-brain barrier transport Semin. Cell Biol. 1991, 2, 419-426
    • (1991) Semin. Cell Biol. , vol.2 , pp. 419-426
    • Pardridge, W.M.1
  • 21
    • 65649123363 scopus 로고    scopus 로고
    • Expression profiling of the solute carrier gene family in the mouse brain
    • Dahlin, A.; Royall, J.; Hohmann, J. G.; Wang, J. Expression profiling of the solute carrier gene family in the mouse brain J. Pharmacol. Exp. Ther. 2009, 329, 558-570
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 558-570
    • Dahlin, A.1    Royall, J.2    Hohmann, J.G.3    Wang, J.4
  • 22
    • 34247882677 scopus 로고    scopus 로고
    • Expression and immunolocalization of the plasma membrane monoamine transporter in the brain
    • DOI 10.1016/j.neuroscience.2007.01.072, PII S0306452207001534
    • Dahlin, A.; Xia, L.; Kong, W.; Hevner, R.; Wang, J. Expression and immunolocalization of the plasma membrane monoamine transporter in the brain Neuroscience 2007, 146, 1193-1211 (Pubitemid 46694120)
    • (2007) Neuroscience , vol.146 , Issue.3 , pp. 1193-1211
    • Dahlin, A.1    Xia, L.2    Kong, W.3    Hevner, R.4    Wang, J.5
  • 23
    • 84055213521 scopus 로고    scopus 로고
    • Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: Relevance to the permeability of antiretroviral therapy at the blood-testis barrier
    • Robillard, K. R.; Hoque, T.; Bendayan, R. Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier J. Pharmacol. Exp. Ther. 2012, 340, 96-108
    • (2012) J. Pharmacol. Exp. Ther. , vol.340 , pp. 96-108
    • Robillard, K.R.1    Hoque, T.2    Bendayan, R.3
  • 24
    • 79960199294 scopus 로고    scopus 로고
    • The blood-testis barrier: The junctional permeability, the proteins and the lipids
    • Pelletier, R. M. The blood-testis barrier: the junctional permeability, the proteins and the lipids Prog. Histochem. Cytochem. 2011, 46, 49-127
    • (2011) Prog. Histochem. Cytochem. , vol.46 , pp. 49-127
    • Pelletier, R.M.1
  • 25
    • 59149089885 scopus 로고    scopus 로고
    • The role of ATP binding cassette transporters in tissue defense and organ regeneration
    • Huls, M.; Russel, F. G.; Masereeuw, R. The role of ATP binding cassette transporters in tissue defense and organ regeneration J. Pharmacol. Exp. Ther. 2009, 328, 3-9
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , pp. 3-9
    • Huls, M.1    Russel, F.G.2    Masereeuw, R.3
  • 26
    • 33751172725 scopus 로고    scopus 로고
    • Drug transport in corneal epithelium and blood-retina barrier: Emerging role of transporters in ocular pharmacokinetics
    • Mannermaa, E.; Vellonen, K. S.; Urtti, A. Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics Adv. Drug Delivery Rev. 2006, 58, 1136-1163
    • (2006) Adv. Drug Delivery Rev. , vol.58 , pp. 1136-1163
    • Mannermaa, E.1    Vellonen, K.S.2    Urtti, A.3
  • 27
    • 63849328972 scopus 로고    scopus 로고
    • Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine
    • Hosoya, K.; Makihara, A.; Tsujikawa, Y.; Yoneyama, D.; Mori, S.; Terasaki, T.; Akanuma, S.; Tomi, M.; Tachikawa, M. Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine J. Pharmacol. Exp. Ther. 2009, 329, 87-93
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 87-93
    • Hosoya, K.1    Makihara, A.2    Tsujikawa, Y.3    Yoneyama, D.4    Mori, S.5    Terasaki, T.6    Akanuma, S.7    Tomi, M.8    Tachikawa, M.9
  • 28
    • 18444398943 scopus 로고    scopus 로고
    • Advances in the cell biology of transport via the inner blood-retinal barrier: Establishment of cell lines and transport functions
    • DOI 10.1248/bpb.28.1
    • Hosoya, K.; Tomi, M. Advances in the cell biology of transport via the inner blood-retinal barrier: establishment of cell lines and transport functions Biol. Pharm. Bull. 2005, 28, 1-8 (Pubitemid 40879774)
    • (2005) Biological and Pharmaceutical Bulletin , vol.28 , Issue.1 , pp. 1-8
    • Hosoya, K.-I.1    Tomi, M.2
  • 29
    • 67651098817 scopus 로고    scopus 로고
    • Expression of ATP-binding cassette transporters at the inner blood-retinal barrier in a neonatal mouse model of oxygen-induced retinopathy
    • Tagami, M.; Kusuhara, S.; Honda, S.; Tsukahara, Y.; Negi, A. Expression of ATP-binding cassette transporters at the inner blood-retinal barrier in a neonatal mouse model of oxygen-induced retinopathy Brain Res. 2009, 1283, 186-193
    • (2009) Brain Res. , vol.1283 , pp. 186-193
    • Tagami, M.1    Kusuhara, S.2    Honda, S.3    Tsukahara, Y.4    Negi, A.5
  • 30
    • 46449098332 scopus 로고    scopus 로고
    • Drug transporter and cytochrome P450 mRNA expression in human ocular barriers: Implications for ocular drug disposition
    • DOI 10.1124/dmd.108.021121
    • Zhang, T.; Xiang, C. D.; Gale, D.; Carreiro, S.; Wu, E. Y.; Zhang, E. Y. Drug transporter and cytochrome P450 mRNA expression in human ocular barriers: implications for ocular drug disposition Drug Metab. Dispos. 2008, 36, 1300-1307 (Pubitemid 351929314)
    • (2008) Drug Metabolism and Disposition , vol.36 , Issue.7 , pp. 1300-1307
    • Zhang, T.1    Xiang, C.D.2    Gale, D.3    Carreiro, S.4    Wu, E.Y.5    Zhang, E.Y.6
  • 33
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl, M. W. A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res. 2001, 29, e45
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 34
    • 84859865809 scopus 로고    scopus 로고
    • R: A language and environment for statistical computing
    • The R Development Core Team
    • The R Development Core Team. R: A language and environment for statistical computing R Found. Stat. Comput. 2011, 1, 409
    • (2011) R Found. Stat. Comput. , vol.1 , pp. 409
  • 35
    • 20744439107 scopus 로고    scopus 로고
    • MADE4: An R package for multivariate analysis of gene expression data
    • DOI 10.1093/bioinformatics/bti394
    • Culhane, A. C.; Thioulouse, J.; Perriere, G.; Higgins, D. G. MADE4: an R package for multivariate analysis of gene expression data Bioinformatics. 2005, 21, 2789-2790 (Pubitemid 40852331)
    • (2005) Bioinformatics , vol.21 , Issue.11 , pp. 2789-2790
    • Culhane, A.C.1    Thioulouse, J.2    Perriere, G.3    Higgins, D.G.4
  • 37
    • 84865157180 scopus 로고    scopus 로고
    • Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update
    • Farooq, A. V.; Shukla, D. Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update Surv. Ophthalmol. 2012, 57 (5) 448-462
    • (2012) Surv. Ophthalmol. , vol.57 , Issue.5 , pp. 448-462
    • Farooq, A.V.1    Shukla, D.2
  • 38
    • 7344245411 scopus 로고    scopus 로고
    • Acyclovir for the prevention of recurrent herpes simplex virus eye disease
    • Herpetic Eye Disease Study Group
    • Herpetic Eye Disease Study Group. Acyclovir for the prevention of recurrent herpes simplex virus eye disease N. Engl. J. Med. 1998, 339, 300-306
    • (1998) N. Engl. J. Med. , vol.339 , pp. 300-306
  • 40
    • 0035136729 scopus 로고    scopus 로고
    • Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease
    • DOI 10.1016/S1350-9462(00)00027-6, PII S1350946200000276
    • Yu, D. Y.; Cringle, S. J. Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease Prog. Retinal Eye Res. 2001, 20, 175-208 (Pubitemid 32153715)
    • (2001) Progress in Retinal and Eye Research , vol.20 , Issue.2 , pp. 175-208
    • Yu, D.-Y.1    Cringle, S.J.2
  • 43
    • 79956016755 scopus 로고    scopus 로고
    • Computational quantification of complex fundus phenotypes in age-related macular degeneration and Stargardt disease
    • Quellec, G.; Russell, S. R.; Scheetz, T. E.; Stone, E. M.; Abramoff, M. D. Computational quantification of complex fundus phenotypes in age-related macular degeneration and Stargardt disease Invest. Ophthalmol. Visual Sci. 2011, 52, 2976-2981
    • (2011) Invest. Ophthalmol. Visual Sci. , vol.52 , pp. 2976-2981
    • Quellec, G.1    Russell, S.R.2    Scheetz, T.E.3    Stone, E.M.4    Abramoff, M.D.5
  • 44
    • 84856985610 scopus 로고    scopus 로고
    • Lipids, lipoproteins, and age-related macular degeneration
    • Ebrahimi, K. B.; Handa, J. T. Lipids, lipoproteins, and age-related macular degeneration J. Lipids 2011, 2011, 802059
    • (2011) J. Lipids , vol.2011 , pp. 802059
    • Ebrahimi, K.B.1    Handa, J.T.2
  • 46
    • 80052197495 scopus 로고    scopus 로고
    • Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration
    • Yu, Y.; Reynolds, R.; Fagerness, J.; Rosner, B.; Daly, M. J.; Seddon, J. M. Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration Invest. Ophthalmol. Visual Sci. 2011, 52, 4663-4670
    • (2011) Invest. Ophthalmol. Visual Sci. , vol.52 , pp. 4663-4670
    • Yu, Y.1    Reynolds, R.2    Fagerness, J.3    Rosner, B.4    Daly, M.J.5    Seddon, J.M.6
  • 47
    • 68049097903 scopus 로고    scopus 로고
    • Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium
    • Duncan, K. G.; Hosseini, K.; Bailey, K. R.; Yang, H.; Lowe, R. J.; Matthes, M. T.; Kane, J. P.; LaVail, M. M.; Schwartz, D. M.; Duncan, J. L. Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium Br. J. Ophthalmol. 2009, 93, 1116-1120
    • (2009) Br. J. Ophthalmol. , vol.93 , pp. 1116-1120
    • Duncan, K.G.1    Hosseini, K.2    Bailey, K.R.3    Yang, H.4    Lowe, R.J.5    Matthes, M.T.6    Kane, J.P.7    Lavail, M.M.8    Schwartz, D.M.9    Duncan, J.L.10
  • 48
    • 33646078329 scopus 로고    scopus 로고
    • ABC A-subfamily transporters: Structure, function and disease
    • Kaminski, W. E.; Piehler, A.; Wenzel, J. J. ABC A-subfamily transporters: structure, function and disease Biochim. Biophys. Acta 2006, 1762, 510-524
    • (2006) Biochim. Biophys. Acta , vol.1762 , pp. 510-524
    • Kaminski, W.E.1    Piehler, A.2    Wenzel, J.J.3
  • 49
    • 34547096264 scopus 로고    scopus 로고
    • Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria
    • DOI 10.1016/j.ejcb.2007.06.001, PII S0171933507000787
    • Godoy, J. R.; Fernandes, C.; Doring, B.; Beuerlein, K.; Petzinger, E.; Geyer, J. Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria Eur. J. Cell Biol. 2007, 86, 445-460 (Pubitemid 47099511)
    • (2007) European Journal of Cell Biology , vol.86 , Issue.8 , pp. 445-460
    • Godoy, J.R.1    Fernandes, C.2    Doring, B.3    Beuerlein, K.4    Petzinger, E.5    Geyer, J.6
  • 50
    • 0023203957 scopus 로고
    • Human interleukin-1 beta gene
    • DOI 10.1016/0378-1119(87)90398-2
    • Bensi, G.; Raugei, G.; Palla, E.; Carinci, V.; Tornese Buonamassa, D.; Melli, M. Human interleukin-1 beta gene Gene 1987, 52, 95-101 (Pubitemid 17076153)
    • (1987) Gene , vol.52 , Issue.1 , pp. 95-101
    • Bensi, G.1    Raugei, G.2    Palla, E.3
  • 51
    • 17844385785 scopus 로고    scopus 로고
    • The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4α and suppressed by bile acids
    • DOI 10.1124/mol.104.010223
    • Popowski, K.; Eloranta, J. J.; Saborowski, M.; Fried, M.; Meier, P. J.; Kullak-Ublick, G. A. The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids Mol. Pharmacol. 2005, 67, 1629-1638 (Pubitemid 40594162)
    • (2005) Molecular Pharmacology , vol.67 , Issue.5 , pp. 1629-1638
    • Popowski, K.1    Eloranta, J.J.2    Saborowski, M.3    Fried, M.4    Meier, P.J.5    Kullak-Ublick, G.A.6
  • 52
    • 34848824067 scopus 로고    scopus 로고
    • Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA
    • Kamiyama, Y.; Matsubara, T.; Yoshinari, K.; Nagata, K.; Kamimura, H.; Yamazoe, Y. Role of human hepatocyte nuclear factor 4alpha in the expression of drug-metabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA Drug Metab. Pharmacokinet. 2007, 22, 287-298
    • (2007) Drug Metab. Pharmacokinet. , vol.22 , pp. 287-298
    • Kamiyama, Y.1    Matsubara, T.2    Yoshinari, K.3    Nagata, K.4    Kamimura, H.5    Yamazoe, Y.6
  • 54
    • 78650224244 scopus 로고    scopus 로고
    • Blocking interleukin-1beta in acute and chronic autoinflammatory diseases
    • Dinarello, C. A. Blocking interleukin-1beta in acute and chronic autoinflammatory diseases J. Intern. Med. 2011, 269, 16-28
    • (2011) J. Intern. Med. , vol.269 , pp. 16-28
    • Dinarello, C.A.1
  • 57
    • 84857395758 scopus 로고    scopus 로고
    • Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs
    • Cheng, Y.; Vapurcuyan, A.; Shahidullah, M.; Aleksunes, L. M.; Pelis, R. M. Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs Drug Metab. Dispos. 2012, 40, 617-624
    • (2012) Drug Metab. Dispos. , vol.40 , pp. 617-624
    • Cheng, Y.1    Vapurcuyan, A.2    Shahidullah, M.3    Aleksunes, L.M.4    Pelis, R.M.5
  • 58
    • 80051982645 scopus 로고    scopus 로고
    • Acyclovir is a substrate for the human breast cancer resistance protein (BCRP/ABCG2): Implications for renal tubular transport and acyclovir-induced nephrotoxicity
    • Gunness, P.; Aleksa, K.; Koren, G. Acyclovir is a substrate for the human breast cancer resistance protein (BCRP/ABCG2): implications for renal tubular transport and acyclovir-induced nephrotoxicity Can. J. Physiol. Pharmacol. 2011, 89, 675-680
    • (2011) Can. J. Physiol. Pharmacol. , vol.89 , pp. 675-680
    • Gunness, P.1    Aleksa, K.2    Koren, G.3
  • 59
    • 0030770508 scopus 로고    scopus 로고
    • Immunity causing blindness: Five different paths to herpes stromal keratitis
    • DOI 10.1016/S0167-5699(97)01114-6, PII S0167569997011146
    • Streilein, J. W.; Dana, M. R.; Ksander, B. R. Immunity causing blindness: five different paths to herpes stromal keratitis Immunol. Today. 1997, 18, 443-449 (Pubitemid 27381987)
    • (1997) Immunology Today , vol.18 , Issue.9 , pp. 443-449
    • Streilein, J.W.1    Dana, M.R.2    Ksander, B.R.3
  • 60
    • 84855482298 scopus 로고    scopus 로고
    • Speed, adaptation, and stability of the response to light in cone photoreceptors: The functional role of Ca-dependent modulation of ligand sensitivity in cGMP-gated ion channels
    • Korenbrot, J. I. Speed, adaptation, and stability of the response to light in cone photoreceptors: the functional role of Ca-dependent modulation of ligand sensitivity in cGMP-gated ion channels J. Gen. Physiol. 2012, 139, 31-56
    • (2012) J. Gen. Physiol. , vol.139 , pp. 31-56
    • Korenbrot, J.I.1
  • 62
    • 33745413471 scopus 로고    scopus 로고
    • ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells
    • DOI 10.1007/s11095-006-0067-2
    • Asashima, T.; Hori, S.; Ohtsuki, S.; Tachikawa, M.; Watanabe, M.; Mukai, C.; Kitagaki, S.; Miyakoshi, N.; Terasaki, T. ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells Pharm. Res. 2006, 23, 1235-1242 (Pubitemid 43946145)
    • (2006) Pharmaceutical Research , vol.23 , Issue.6 , pp. 1235-1242
    • Asashima, T.1    Hori, S.2    Ohtsuki, S.3    Tachikawa, M.4    Watanabe, M.5    Mukai, C.6    Kitagaki, S.7    Miyakoshi, N.8    Terasaki, T.9
  • 63
    • 78651286291 scopus 로고    scopus 로고
    • Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons
    • Lambert, W. S.; Ruiz, L.; Crish, S. D.; Wheeler, L. A.; Calkins, D. J. Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons Mol. Neurodegener. 2011, 6, 4
    • (2011) Mol. Neurodegener. , vol.6 , pp. 4
    • Lambert, W.S.1    Ruiz, L.2    Crish, S.D.3    Wheeler, L.A.4    Calkins, D.J.5
  • 65
    • 0034087276 scopus 로고    scopus 로고
    • Expression of the extraneuronal monoamine transporter in RPE and neural retina
    • Rajan, P. D.; Kekuda, R.; Chancy, C. D.; Huang, W.; Ganapathy, V.; Smith, S. B. Expression of the extraneuronal monoamine transporter in RPE and neural retina Curr. Eye Res. 2000, 20, 195-204 (Pubitemid 30209651)
    • (2000) Current Eye Research , vol.20 , Issue.3 , pp. 195-204
    • Rajan, P.D.1    Kekuda, R.2    Chancy, C.D.3    Huang, W.4    Ganapathy, V.5    Smith, S.B.6
  • 66
    • 33645101081 scopus 로고    scopus 로고
    • Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters
    • Li, M.; Anderson, G. D.; Phillips, B. R.; Kong, W.; Shen, D. D.; Wang, J. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters Drug Metab. Dispos. 2006, 34, 547-555
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 547-555
    • Li, M.1    Anderson, G.D.2    Phillips, B.R.3    Kong, W.4    Shen, D.D.5    Wang, J.6
  • 67
    • 0032916827 scopus 로고    scopus 로고
    • Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line
    • Guo, A.; Hu, P.; Balimane, P. V.; Leibach, F. H.; Sinko, P. J. Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line J. Pharmacol. Exp. Ther. 1999, 289, 448-454 (Pubitemid 29156062)
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.289 , Issue.1 , pp. 448-454
    • Guo, A.1    Hu, P.2    Balimane, P.V.3    Leibach, F.H.4    Sinko, P.J.5
  • 69
    • 27744454598 scopus 로고    scopus 로고
    • Drug specificity and intestinal membrane localization of human organic cation transporters (OCT)
    • DOI 10.1016/j.bcp.2005.09.011, PII S0006295205005885
    • Muller, J.; Lips, K. S.; Metzner, L.; Neubert, R. H.; Koepsell, H.; Brandsch, M. Drug specificity and intestinal membrane localization of human organic cation transporters (OCT) Biochem. Pharmacol. 2005, 70, 1851-1860 (Pubitemid 41612016)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.12 , pp. 1851-1860
    • Muller, J.1    Lips, K.S.2    Metzner, L.3    Neubert, R.H.H.4    Koepsell, H.5    Brandsch, M.6
  • 72
    • 33744513103 scopus 로고    scopus 로고
    • Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain
    • DOI 10.1016/j.neuropharm.2006.01.005, PII S0028390806000190
    • Amphoux, A.; Vialou, V.; Drescher, E.; Bruss, M.; Mannoury La Cour, C.; Rochat, C.; Millan, M. J.; Giros, B.; Bonisch, H.; Gautron, S. Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain Neuropharmacology 2006, 50, 941-952 (Pubitemid 43810126)
    • (2006) Neuropharmacology , vol.50 , Issue.8 , pp. 941-952
    • Amphoux, A.1    Vialou, V.2    Drescher, E.3    Bruss, M.4    La Cour, C.M.5    Rochat, C.6    Millan, M.J.7    Giros, B.8    Bonisch, H.9    Gautron, S.10
  • 77
    • 34247236764 scopus 로고    scopus 로고
    • Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein
    • DOI 10.1124/jpet.106.116517
    • Chu, X. Y.; Bleasby, K.; Yabut, J.; Cai, X.; Chan, G. H.; Hafey, M. J.; Xu, S.; Bergman, A. J.; Braun, M. P.; Dean, D. C.; Evers, R. Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein J. Pharmacol. Exp. Ther. 2007, 321, 673-683 (Pubitemid 46624514)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.321 , Issue.2 , pp. 673-683
    • Chu, X.-Y.1    Bleasby, K.2    Yabut, J.3    Cai, X.4    Chan, G.H.5    Hafey, M.J.6    Xu, S.7    Bergman, A.J.8    Braun, M.P.9    Dean, D.C.10    Evers, R.11
  • 78
    • 0034008388 scopus 로고    scopus 로고
    • Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1
    • Ho, E. S.; Lin, D. C.; Mendel, D. B.; Cihlar, T. Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1 J. Am. Soc. Nephrol. 2000, 11, 383-393 (Pubitemid 30115068)
    • (2000) Journal of the American Society of Nephrology , vol.11 , Issue.3 , pp. 383-393
    • Ho, E.S.1    Lin, D.C.2    Mendel, D.B.3    Cihlar, T.4
  • 79
    • 0032856603 scopus 로고    scopus 로고
    • The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1
    • Cihlar, T.; Lin, D. C.; Pritchard, J. B.; Fuller, M. D.; Mendel, D. B.; Sweet, D. H. The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1 Mol. Pharmacol. 1999, 56, 570-580 (Pubitemid 29406884)
    • (1999) Molecular Pharmacology , vol.56 , Issue.3 , pp. 570-580
    • Cihlar, T.1    Lin, D.C.2    Pritchard, J.B.3    Fuller, M.D.4    Mendel, D.B.5    Sweet, D.H.6
  • 80
    • 0034662273 scopus 로고    scopus 로고
    • Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter
    • DOI 10.1006/abio.2000.4633
    • Cihlar, T.; Ho, E. S. Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1 Anal. Biochem. 2000, 283, 49-55 (Pubitemid 30469749)
    • (2000) Analytical Biochemistry , vol.283 , Issue.1 , pp. 49-55
    • Cihlar, T.1    Ho, E.S.2
  • 82
    • 17844378450 scopus 로고    scopus 로고
    • Possible involvement of organic anion transporter 2 on the interaction of theophylline with erythromycin in the human liver
    • DOI 10.1124/dmd.104.003301
    • Kobayashi, Y.; Sakai, R.; Ohshiro, N.; Ohbayashi, M.; Kohyama, N.; Yamamoto, T. Possible involvement of organic anion transporter 2 on the interaction of theophylline with erythromycin in the human liver Drug Metab. Dispos. 2005, 33, 619-622 (Pubitemid 40593874)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.5 , pp. 619-622
    • Kobayashi, Y.1    Sakai, R.2    Ohshiro, N.3    Ohbayashi, M.4    Kohyama, N.5    Yamamoto, T.6
  • 83
    • 17644380567 scopus 로고    scopus 로고
    • Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7])
    • DOI 10.1211/0022357055966
    • Kobayashi, Y.; Ohshiro, N.; Sakai, R.; Ohbayashi, M.; Kohyama, N.; Yamamoto, T. Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]) J. Pharm. Pharmacol. 2005, 57, 573-578 (Pubitemid 40562396)
    • (2005) Journal of Pharmacy and Pharmacology , vol.57 , Issue.5 , pp. 573-578
    • Kobayashi, Y.1    Ohshiro, N.2    Sakai, R.3    Ohbayashi, M.4    Kohyama, N.5    Yamamoto, T.6
  • 84
    • 34250005960 scopus 로고    scopus 로고
    • +-organic cation antiporters
    • DOI 10.1016/j.bcp.2007.04.010, PII S0006295207002298
    • Tanihara, Y.; Masuda, S.; Sato, T.; Katsura, T.; Ogawa, O.; Inui, K. Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters Biochem. Pharmacol. 2007, 74, 359-371 (Pubitemid 46890818)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.2 , pp. 359-371
    • Tanihara, Y.1    Masuda, S.2    Sato, T.3    Katsura, T.4    Ogawa, O.5    Inui, K.-i.6
  • 86
    • 12344333505 scopus 로고    scopus 로고
    • Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium
    • DOI 10.1016/j.exer.2004.08.013, PII S0014483504002337
    • Gao, B.; Huber, R. D.; Wenzel, A.; Vavricka, S. R.; Ismair, M. G.; Reme, C.; Meier, P. J. Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium Exp. Eye Res. 2005, 80, 61-72 (Pubitemid 40126514)
    • (2005) Experimental Eye Research , vol.80 , Issue.1 , pp. 61-72
    • Gao, B.1    Huber, R.D.2    Wenzel, A.3    Vavricka, S.R.4    Ismair, M.G.5    Reme, C.6    Meier, P.J.7
  • 91
    • 0032987924 scopus 로고    scopus 로고
    • Characterization of cyclosporin A transport in cultured rabbit corneal epithelial cells: P-glycoprotein transport activity and binding to cyclophilin
    • Kawazu, K.; Yamada, K.; Nakamura, M.; Ota, A. Characterization of cyclosporin A transport in cultured rabbit corneal epithelial cells: P-glycoprotein transport activity and binding to cyclophilin Invest. Ophthalmol. Visual Sci. 1999, 40, 1738-1744 (Pubitemid 29297149)
    • (1999) Investigative Ophthalmology and Visual Science , vol.40 , Issue.8 , pp. 1738-1744
    • Kawazu, K.1    Yamada, K.2    Nakamura, M.3    Ota, A.4
  • 93
    • 63849344988 scopus 로고    scopus 로고
    • Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids
    • Hariharan, S.; Gunda, S.; Mishra, G. P.; Pal, D.; Mitra, A. K. Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids Pharm. Res. 2009, 26, 1270-1282
    • (2009) Pharm. Res. , vol.26 , pp. 1270-1282
    • Hariharan, S.1    Gunda, S.2    Mishra, G.P.3    Pal, D.4    Mitra, A.K.5
  • 94
    • 33846557371 scopus 로고    scopus 로고
    • Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol
    • DOI 10.1042/BJ20060632
    • Kimura, Y.; Kioka, N.; Kato, H.; Matsuo, M.; Ueda, K. Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol Biochem. J. 2007, 401, 597-605 (Pubitemid 46166441)
    • (2007) Biochemical Journal , vol.401 , Issue.2 , pp. 597-605
    • Kimura, Y.1    Kioka, N.2    Kato, H.3    Matsuo, M.4    Ueda, K.5
  • 96
    • 0034604707 scopus 로고    scopus 로고
    • MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drags as judged by interference with nucleotide trapping
    • DOI 10.1074/jbc.M909002199
    • Smith, A. J.; van Helvoort, A.; van Meer, G.; Szabo, K.; Welker, E.; Szakacs, G.; Varadi, A.; Sarkadi, B.; Borst, P. MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping J. Biol. Chem. 2000, 275, 23530-23539 (Pubitemid 30624635)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.31 , pp. 23530-23539
    • Smith, A.J.1    Van Helvoort, A.2    Van Meer, G.3    Szabo, K.4    Welker, E.5    Szakacs, G.6    Varadi, A.7    Sarkadi, B.8    Borst, P.9
  • 97
    • 34047258853 scopus 로고    scopus 로고
    • Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux
    • DOI 10.1016/j.ijpharm.2006.11.031, PII S037851730600980X
    • Karla, P. K.; Pal, D.; Quinn, T.; Mitra, A. K. Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux Int. J. Pharm. 2007, 336, 12-21 (Pubitemid 46551552)
    • (2007) International Journal of Pharmaceutics , vol.336 , Issue.1 , pp. 12-21
    • Karla, P.K.1    Pal, D.2    Quinn, T.3    Mitra, A.K.4
  • 98
    • 68149176787 scopus 로고    scopus 로고
    • Expression of multidrug resistance associated protein 5 (MRP5) on cornea and its role in drug efflux
    • Karla, P. K.; Quinn, T. L.; Herndon, B. L.; Thomas, P.; Pal, D.; Mitra, A. Expression of multidrug resistance associated protein 5 (MRP5) on cornea and its role in drug efflux J. Ocul. Pharmacol. Ther. 2009, 25, 121-132
    • (2009) J. Ocul. Pharmacol. Ther. , vol.25 , pp. 121-132
    • Karla, P.K.1    Quinn, T.L.2    Herndon, B.L.3    Thomas, P.4    Pal, D.5    Mitra, A.6
  • 99
    • 34250183824 scopus 로고    scopus 로고
    • Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression
    • Stojic, J.; Stohr, H.; Weber, B. H. Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression BMC Mol. Biol. 2007, 8, 42
    • (2007) BMC Mol. Biol. , vol.8 , pp. 42
    • Stojic, J.1    Stohr, H.2    Weber, B.H.3
  • 100
    • 59449096752 scopus 로고    scopus 로고
    • Molecular expression and functional evidence of a drug efflux pump (BCRP) in human corneal epithelial cells
    • Karla, P. K.; Earla, R.; Boddu, S. H.; Johnston, T. P.; Pal, D.; Mitra, A. Molecular expression and functional evidence of a drug efflux pump (BCRP) in human corneal epithelial cells Curr. Eye Res. 2009, 34, 1-9
    • (2009) Curr. Eye Res. , vol.34 , pp. 1-9
    • Karla, P.K.1    Earla, R.2    Boddu, S.H.3    Johnston, T.P.4    Pal, D.5    Mitra, A.6
  • 102
    • 77957283600 scopus 로고    scopus 로고
    • MRP4 knockdown enhances migration, suppresses apoptosis, and produces aggregated morphology in human retinal vascular endothelial cells
    • Tagami, M.; Kusuhara, S.; Imai, H.; Uemura, A.; Honda, S.; Tsukahara, Y.; Negi, A. MRP4 knockdown enhances migration, suppresses apoptosis, and produces aggregated morphology in human retinal vascular endothelial cells Biochem. Biophys. Res. Commun. 2010, 400, 593-598
    • (2010) Biochem. Biophys. Res. Commun. , vol.400 , pp. 593-598
    • Tagami, M.1    Kusuhara, S.2    Imai, H.3    Uemura, A.4    Honda, S.5    Tsukahara, Y.6    Negi, A.7


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