The role of blood-ocular barrier transporters in retinal drug disposition: An overview

Expert Opinion on Drug Metabolism and Toxicology

Volumn 6, Issue 9, 2010, Pages 1111-1124

  Tomi, Masatoshi ^a,b   Hosoya, Ken Ichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

ABC transporters; Bloodaqueous barrier; Bloodocular barrier; Bloodretinal barrier; Drug transporters; Retina; SLC transporters

Indexed keywords

4 AMINOHIPPURIC ACID; ABC TRANSPORTER; ABC TRANSPORTER G1; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); CYCLOSPORIN A; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; FEXOFENADINE; FLUORESCEIN; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUCURONIDE; IRINOTECAN; MERCAPTOPURINE; METHOTREXATE; MONOCARBOXYLATE TRANSPORTER 1; MORPHINE 3 GLUCURONIDE; ORGANIC ANION TRANSPORTER; PACLITAXEL; PENICILLIN G; PITAVASTATIN; QUINIDINE; REDUCED FOLATE CARRIER; SLC29 PROTEIN; SLC7 PROTEIN; TOPOTECAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; VINBLASTINE;

AQUEOUS HUMOR FLOW; BLOOD EYE BARRIER; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; DRUG PENETRATION; DRUG TRANSPORT; HOMEOSTASIS; HUMAN; INFORMATION; NONHUMAN; RETINA DISEASE; REVIEW;

ANIMALS; AQUEOUS HUMOR; ATP-BINDING CASSETTE TRANSPORTERS; BLOOD-AQUEOUS BARRIER; BLOOD-RETINAL BARRIER; CELL LINE; DRUG DELIVERY SYSTEMS; EYE; HOMEOSTASIS; HUMANS; MEMBRANE TRANSPORT PROTEINS; METABOLIC DETOXICATION, DRUG; RETINA; RETINAL DISEASES;

EID: 77955796725     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.2010.486401     Document Type: Review

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