Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs

Drug Metabolism and Disposition

Volumn 40, Issue 3, 2012, Pages 617-624

  Cheng, Yaofeng ^a   Vapurcuyan, Arpine ^a   Shahidullah, Mohammad ^b   Aleksunes, Lauren M ^c   Pelis, Ryan M ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; GANCICLOVIR; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 2; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; PENCICLOVIR; RNA;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG ELIMINATION; DRUG STRUCTURE; DRUG TRANSPORT; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; MALE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION;

ACYCLOVIR; ADOLESCENT; ADULT; ANTIVIRAL AGENTS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CYCLIC GMP; FEMALE; GANCICLOVIR; GUANINE; HEK293 CELLS; HUMANS; KIDNEY; MALE; MIDDLE AGED; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; ORGANIC CATION TRANSPORT PROTEINS; RNA, MESSENGER; YOUNG ADULT;

EID: 84857395758     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.042036     Document Type: Article

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