Molecular evidence and functional expression of a novel drug efflux pump (ABCC2) in human corneal epithelium and rabbit cornea and its role in ocular drug efflux

International Journal of Pharmaceutics

Volumn 336, Issue 1, 2007, Pages 12-21

  Karla, Pradeep K ^a   Pal, Dhananjay ^a   Quinn, Tim ^b   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

Author keywords

Human corneal epithelial cell; Multidrug resistance associated protein (MRP); Ocular drug efflux; Specific MRP inhibitor

Indexed keywords

CARBON 14; CYCLOSPORIN; ERYTHROMYCIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; TRITIUM; VERLUKAST;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORNEA; CORNEA EPITHELIUM; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; EFFUSION; FUNCTIONAL ASSESSMENT; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT FAILURE; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; CORNEA; CYCLOSPORINE; DOGS; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; ERYTHROMYCIN; GENE EXPRESSION; HUMANS; MALE; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PHARMACEUTICAL PREPARATIONS; PROPIONATES; QUINOLINES; RABBITS;

EID: 34047258853     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.11.031     Document Type: Article

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