The prostaglandin transporter OATP2A1 is expressed in human ocular tissues and transports the antiglaucoma prostanoid latanoprost

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 5, 2010, Pages 2504-2511

  Kraft, Michaela E ^a   Glaeser, Hartmut ^a   Mandery, Kathrin ^a   König, Jörg ^a   Auge, Daniel ^a   Fromm, Martin F ^a   Schlötzer Schrehardt, Ursula ^a   Welge Lüssen, Ulrich ^a   Kruse, Friedrich E ^a   Zolk, Oliver ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANION TRANSPORT PROTEIN; LATANOPROST; LATANOPROST ACID; MESSENGER RNA; OATP2A1 PROTEIN; OATP2B1 PROTEIN; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; ANTIHYPERTENSIVE AGENT; ORGANIC ANION TRANSPORTER; PROSTAGLANDIN F; SLCO2A1 PROTEIN, HUMAN; SLCO2B1 PROTEIN, HUMAN;

AQUEOUS HUMOR; ARTICLE; BINDING AFFINITY; CHOROID; CHOROID VASCULARIZATION; CILIARY BODY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG TRANSPORT; DRUG UPTAKE; EMBRYO; ENZYME SUBSTRATE; EYE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IMMUNOFLUORESCENCE; NUCLEOTIDE SEQUENCE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; SCHLEMM CANAL; TRABECULAR MESHWORK; AGED; ANTERIOR EYE SEGMENT; CELL LINE; DRUG EFFECT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GLAUCOMA; INTRAOCULAR PRESSURE; KIDNEY; LIQUID CHROMATOGRAPHY; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; TRANSPORT AT THE CELLULAR LEVEL;

AGED; AGED, 80 AND OVER; ANTERIOR EYE SEGMENT; ANTIHYPERTENSIVE AGENTS; BIOLOGICAL TRANSPORT; CELL LINE; CHOROID; CHROMATOGRAPHY, LIQUID; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION; GLAUCOMA; HUMANS; INTRAOCULAR PRESSURE; KIDNEY; MALE; MIDDLE AGED; ORGANIC ANION TRANSPORTERS; PROSTAGLANDINS F, SYNTHETIC; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TANDEM MASS SPECTROMETRY; TRANSFECTION;

EID: 77952497062     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4290     Document Type: Article

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