-
1
-
-
41149111580
-
Chemokines and their receptors: Drug targets in immunity and inflammation
-
Viola, A. and Luster, A.D. (2008) Chemokines and their receptors: drug targets in immunity and inflammation. Annu. Rev. Pharmacol. Toxicol. 48, 171-197
-
(2008)
Annu. Rev. Pharmacol. Toxicol.
, vol.48
, pp. 171-197
-
-
Viola, A.1
Luster, A.D.2
-
2
-
-
0034144269
-
Chemokines: A new classification system and their role in immunity
-
Zlotnik, A. and Yoshie, O. (2000) Chemokines: a new classification system and their role in immunity. Immunity 12, 121-127
-
(2000)
Immunity
, vol.12
, pp. 121-127
-
-
Zlotnik, A.1
Yoshie, O.2
-
3
-
-
0034092634
-
International union of pharmacology. XXII. Nomenclature for chemokine receptors
-
Murphy, P.M. et al. (2000) International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52, 145-176
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 145-176
-
-
Murphy, P.M.1
-
4
-
-
81355156238
-
Guide to receptors and channels (GRAC), 5th edition
-
Alexander, S.P. et al. (2011) Guide to receptors and channels (GRAC), 5th edition. Br. J. Pharmacol. 164 (Suppl. 1), S1-S324
-
(2011)
Br. J. Pharmacol.
, vol.164
, Issue.SUPPL. 1
-
-
Alexander, S.P.1
-
5
-
-
13544251377
-
CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor
-
Casarosa, P. et al. (2005) CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor. J. Biol. Chem. 280, 3275-3285
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3275-3285
-
-
Casarosa, P.1
-
6
-
-
10744224514
-
A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions
-
Kashiwazaki, M. et al. (2003) A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions. Int. Immunol. 15, 1219-1227
-
(2003)
Int. Immunol.
, vol.15
, pp. 1219-1227
-
-
Kashiwazaki, M.1
-
7
-
-
0034653894
-
Cutting edge: Identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK
-
Gosling, J. et al. (2000) Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK. J. Immunol. 164, 2851-2856
-
(2000)
J. Immunol.
, vol.164
, pp. 2851-2856
-
-
Gosling, J.1
-
8
-
-
78751498756
-
Functional selectivity and biased receptor signaling
-
Kenakin, T. (2011) Functional selectivity and biased receptor signaling. J. Pharmacol. Exp. Ther. 336, 296-302
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.336
, pp. 296-302
-
-
Kenakin, T.1
-
9
-
-
0035856010
-
Chemokines and the molecular basis of cancer metastasis
-
Murphy, P. (2001) Chemokines and the molecular basis of cancer metastasis. N. Engl. J. Med. 345, 3
-
(2001)
N. Engl. J. Med.
, vol.345
, pp. 3
-
-
Murphy, P.1
-
10
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill, F. (2004) Cancer and the chemokine network. Nat. Rev. Cancer 4, 540-550
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 540-550
-
-
Balkwill, F.1
-
11
-
-
32144454172
-
The many roles of chemokines and chemokine receptors in inflammation
-
Charo, I.F. and Ransohoff, R.M. (2006) The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354, 610-621
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 610-621
-
-
Charo, I.F.1
Ransohoff, R.M.2
-
12
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
Berger, E.A. et al. (1999) Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17, 657-700
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
-
13
-
-
84873062910
-
Pharmacological characterisation of a smallmolecule agonist for the chemokine receptor CXCR3
-
Scholten, D. et al. (2011) Pharmacological characterisation of a smallmolecule agonist for the chemokine receptor CXCR3. Br. J. Pharmacol. 165, 1617-1643
-
(2011)
Br. J. Pharmacol.
, vol.165
, pp. 1617-1643
-
-
Scholten, D.1
-
14
-
-
79955476625
-
Overcoming hurdles in developing successful drugs targeting chemokine receptors
-
Schall, T.J. and Proudfoot, A.E. (2011) Overcoming hurdles in developing successful drugs targeting chemokine receptors. Nat. Rev. Immunol. 11, 355-363
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 355-363
-
-
Schall, T.J.1
Proudfoot, A.E.2
-
15
-
-
54849146700
-
Maraviroc for previously treated patients with R5 HIV-1 infection
-
Gulick, R.M. et al. (2008) Maraviroc for previously treated patients with R5 HIV-1 infection. N. Engl. J. Med. 359, 1429-1441
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1429-1441
-
-
Gulick, R.M.1
-
16
-
-
84863776051
-
Hematopoietic stem cell mobilizing agents GCSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation
-
Winkler, I.G. et al. (2012) Hematopoietic stem cell mobilizing agents GCSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia 26, 1594-1601
-
(2012)
Leukemia
, vol.26
, pp. 1594-1601
-
-
Winkler, I.G.1
-
17
-
-
80051796965
-
Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells
-
Dar, A. et al. (2011) Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells. Leukemia 25, 1286-1296
-
(2011)
Leukemia
, vol.25
, pp. 1286-1296
-
-
Dar, A.1
-
18
-
-
78650573881
-
CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells
-
Jähnichen, S. et al. (2010) CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells. Proc. Natl. Acad. Sci. U. S. A. 107, 20565-20570
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 20565-20570
-
-
Jähnichen, S.1
-
19
-
-
79954425389
-
Structural insights into adrenergic receptor function and pharmacology
-
Kobilka, B.K. (2011) Structural insights into adrenergic receptor function and pharmacology. Trends Pharmacol. Sci. 32, 213-218
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 213-218
-
-
Kobilka, B.K.1
-
20
-
-
84855799592
-
Diversity and modularity of G protein-coupled receptor structures
-
Katritch, V. et al. (2012) Diversity and modularity of G protein-coupled receptor structures. Trends Pharmacol. Sci. 33, 17-27
-
(2012)
Trends Pharmacol. Sci.
, vol.33
, pp. 17-27
-
-
Katritch, V.1
-
21
-
-
80053615320
-
The significance of G protein-coupled receptor crystallography for drug discovery
-
Salon, J.A. et al. (2011) The significance of G protein-coupled receptor crystallography for drug discovery. Pharmacol. Rev. 63, 901-937
-
(2011)
Pharmacol. Rev.
, vol.63
, pp. 901-937
-
-
Salon, J.A.1
-
22
-
-
80051521545
-
Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment
-
Kufareva, I. et al. (2011) Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure 19, 1108-1126
-
(2011)
Structure
, vol.19
, pp. 1108-1126
-
-
Kufareva, I.1
-
23
-
-
0004812552
-
Total replacement of methionine by selenomethionine in the proteins of Escherichia coli
-
Cohen, G.N. and Cowie, D.B. (1957) Total replacement of methionine by selenomethionine in the proteins of Escherichia coli. C. R. Hebd. Seances Acad. Sci. 244, 680-683
-
(1957)
C. R. Hebd. Seances Acad. Sci.
, vol.244
, pp. 680-683
-
-
Cohen, G.N.1
Cowie, D.B.2
-
24
-
-
0037548053
-
Semisynthesis of proteins by expressed protein ligation
-
Muir, T.W. (2003) Semisynthesis of proteins by expressed protein ligation. Annu. Rev. Biochem. 72, 249-289
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 249-289
-
-
Muir, T.W.1
-
25
-
-
14744280119
-
'100 years of peptide synthesis': Ligation methods for peptide and protein synthesis with applications to beta-peptide assemblies
-
Kimmerlin, T. and Seebach, D. (2005) '100 years of peptide synthesis': ligation methods for peptide and protein synthesis with applications to beta-peptide assemblies. J. Pept. Res. 65, 229-260
-
(2005)
J. Pept. Res.
, vol.65
, pp. 229-260
-
-
Kimmerlin, T.1
Seebach, D.2
-
26
-
-
57749121492
-
Chemoselective ligation and modification strategies for peptides and proteins
-
Hackenberger, C.P. and Schwarzer, D. (2008) Chemoselective ligation and modification strategies for peptides and proteins. Angew. Chem. Int. Ed. Engl. 47, 10030-10074
-
(2008)
Angew. Chem. Int. Ed. Engl.
, vol.47
, pp. 10030-10074
-
-
Hackenberger, C.P.1
Schwarzer, D.2
-
27
-
-
69849107116
-
Incorporation of non-natural modules into proteins: Structural features beyond the genetic code
-
Arnold, U. (2009) Incorporation of non-natural modules into proteins: structural features beyond the genetic code. Biotechnol. Lett. 31, 1129-1139
-
(2009)
Biotechnol. Lett.
, vol.31
, pp. 1129-1139
-
-
Arnold, U.1
-
28
-
-
62649104324
-
Expanding the genetic code for biological studies
-
Wang, Q. et al. (2009) Expanding the genetic code for biological studies. Chem. Biol. 16, 323-336
-
(2009)
Chem. Biol.
, vol.16
, pp. 323-336
-
-
Wang, Q.1
-
29
-
-
77953643054
-
Adding new chemistries to the genetic code
-
Liu, C.C. and Schultz, P.G. (2010) Adding new chemistries to the genetic code. Annu. Rev. Biochem. 79, 413-444
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 413-444
-
-
Liu, C.C.1
Schultz, P.G.2
-
30
-
-
0025235971
-
Chemical modifications of proteins: History and applications
-
Means, G.E. and Feeney, R.E. (1990) Chemical modifications of proteins: history and applications. Bioconjug. Chem. 1, 2-12
-
(1990)
Bioconjug. Chem.
, vol.1
, pp. 2-12
-
-
Means, G.E.1
Feeney, R.E.2
-
31
-
-
27944433008
-
Protein semi-synthesis: New proteins for functional and structural studies
-
Durek, T. and Becker, C.F. (2005) Protein semi-synthesis: new proteins for functional and structural studies. Biomol. Eng. 22, 153-172
-
(2005)
Biomol. Eng.
, vol.22
, pp. 153-172
-
-
Durek, T.1
Becker, C.F.2
-
32
-
-
0033894562
-
Protein splicing and its applications
-
Perler, F.B. and Adam, E. (2000) Protein splicing and its applications. Curr. Opin. Biotechnol. 11, 377-383
-
(2000)
Curr. Opin. Biotechnol.
, vol.11
, pp. 377-383
-
-
Perler, F.B.1
Adam, E.2
-
34
-
-
0345742616
-
A new strategy for the synthesis of glycoproteins
-
Zhang, Z. et al. (2004) A new strategy for the synthesis of glycoproteins. Science 303, 371-373
-
(2004)
Science
, vol.303
, pp. 371-373
-
-
Zhang, Z.1
-
35
-
-
10044288227
-
Site-specific incorporation of the mucin-type Nacetylgalactosamine-alpha- O-threonine into protein in Escherichia coli
-
Xu, R. et al. (2004) Site-specific incorporation of the mucin-type Nacetylgalactosamine-alpha-O-threonine into protein in Escherichia coli. J. Am. Chem. Soc. 126, 15654-15655
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 15654-15655
-
-
Xu, R.1
-
36
-
-
33846809165
-
Site-specific incorporation of a (19)F-amino acid into proteins as an NMR probe for characterizing protein structure and reactivity
-
Jackson, J.C. et al. (2007) Site-specific incorporation of a (19)F-amino acid into proteins as an NMR probe for characterizing protein structure and reactivity. J. Am. Chem. Soc. 129, 1160-1166
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 1160-1166
-
-
Jackson, J.C.1
-
37
-
-
79957994698
-
Site-specific in vitro and in vivo incorporation of molecular probes to study G-protein-coupled receptors
-
Daggett, K.A. and Sakmar, T.P. (2011) Site-specific in vitro and in vivo incorporation of molecular probes to study G-protein-coupled receptors. Curr. Opin. Chem. Biol. 15, 392-398
-
(2011)
Curr. Opin. Chem. Biol.
, vol.15
, pp. 392-398
-
-
Daggett, K.A.1
Sakmar, T.P.2
-
38
-
-
38349107042
-
Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis
-
Ye, S.X. et al. (2008) Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J. Biol. Chem. 283, 1525-1533
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1525-1533
-
-
Ye, S.X.1
-
39
-
-
67349121748
-
FTIR analysis of GPCR activation using azido probes
-
Ye, S. et al. (2009) FTIR analysis of GPCR activation using azido probes. Nat. Chem. Biol. 5, 397-399
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 397-399
-
-
Ye, S.1
-
40
-
-
77951877209
-
Tracking G-protein-coupled receptor activation using genetically encoded infrared probes
-
Ye, S. et al. (2010) Tracking G-protein-coupled receptor activation using genetically encoded infrared probes. Nature 464, 1386-1389
-
(2010)
Nature
, vol.464
, pp. 1386-1389
-
-
Ye, S.1
-
41
-
-
0034014055
-
Tyrosine sulfation: A modulator of extracellular protein-protein interactions
-
Kehoe, J.W. and Bertozzi, C.R. (2000) Tyrosine sulfation: a modulator of extracellular protein-protein interactions. Chem. Biol. 7, R57-R61
-
(2000)
Chem. Biol.
, vol.7
-
-
Kehoe, J.W.1
Bertozzi, C.R.2
-
42
-
-
54849434087
-
Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
-
Veldkamp, C.T. et al. (2008) Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci. Signal. 1, ra4
-
(2008)
Sci. Signal.
, vol.1
-
-
Veldkamp, C.T.1
-
43
-
-
33745173829
-
Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12)
-
Veldkamp, C.T. et al. (2006) Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12). J. Mol. Biol. 359, 1400-1409
-
(2006)
J. Mol. Biol.
, vol.359
, pp. 1400-1409
-
-
Veldkamp, C.T.1
-
44
-
-
0029745052
-
Cation-pi interactions in aromatics of biological and medicinal interest: Electrostatic potential surfaces as a useful qualitative guide
-
Mecozzi, S. et al. (1996) Cation-pi interactions in aromatics of biological and medicinal interest: electrostatic potential surfaces as a useful qualitative guide. Proc. Natl. Acad. Sci. U. S. A. 93, 10566-10571
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 10566-10571
-
-
Mecozzi, S.1
-
45
-
-
67749122587
-
Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids
-
Torrice, M.M. et al. (2009) Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids. Proc. Natl. Acad. Sci. U. S. A. 106, 11919-11924
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 11919-11924
-
-
Torrice, M.M.1
-
46
-
-
79955445476
-
Mapping the ligand-binding site on a G proteincoupled receptor (GPCR) using genetically encoded photocrosslinkers
-
Grunbeck, A. et al. (2011) Mapping the ligand-binding site on a G proteincoupled receptor (GPCR) using genetically encoded photocrosslinkers. Biochemistry 50, 3411-3413
-
(2011)
Biochemistry
, vol.50
, pp. 3411-3413
-
-
Grunbeck, A.1
-
47
-
-
84862526546
-
Genetically-encoded photocrosslinkers map the binding site of an allosteric drug on a G protein-coupled receptor
-
Grunbeck, A. et al. (2012) Genetically-encoded photocrosslinkers map the binding site of an allosteric drug on a G protein-coupled receptor. ACS Chem. Biol. 7, 967-972
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 967-972
-
-
Grunbeck, A.1
-
48
-
-
27744548649
-
The discovery of the CCR5 receptor antagonist, UK-427,857, a new agent for the treatment of HIV infection and AIDS
-
Wood, A. and Armour, D. (2005) The discovery of the CCR5 receptor antagonist, UK-427,857, a new agent for the treatment of HIV infection and AIDS. Prog. Med. Chem. 43, 239-271
-
(2005)
Prog. Med. Chem.
, vol.43
, pp. 239-271
-
-
Wood, A.1
Armour, D.2
-
49
-
-
71749092103
-
Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy
-
Tikhonova, I.G. and Costanzi, S. (2009) Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy. Curr. Pharm. Des. 15, 4003-4016
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 4003-4016
-
-
Tikhonova, I.G.1
Costanzi, S.2
-
50
-
-
73849149844
-
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
-
Bokoch, M.P. et al. (2010) Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature 463, 108-112
-
(2010)
Nature
, vol.463
, pp. 108-112
-
-
Bokoch, M.P.1
-
51
-
-
71049116053
-
Time-resolved methods in biophysics. 10. Timeresolved FT-IR difference spectroscopy and the application to membrane proteins
-
Radu, I. et al. (2009) Time-resolved methods in biophysics. 10. Timeresolved FT-IR difference spectroscopy and the application to membrane proteins. Photochem. Photobiol. Sci. 8, 1517-1528
-
(2009)
Photochem. Photobiol. Sci.
, vol.8
, pp. 1517-1528
-
-
Radu, I.1
-
52
-
-
33745946445
-
A genetically encoded fluorescent amino acid
-
Wang, J. et al. (2006) A genetically encoded fluorescent amino acid. J. Am. Chem. Soc. 128, 8738-8739
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 8738-8739
-
-
Wang, J.1
-
53
-
-
33745633570
-
A genetically encoded fluorescent amino acid
-
Summerer, D. et al. (2006) A genetically encoded fluorescent amino acid. Proc. Natl. Acad. Sci. U. S. A. 103, 9785-9789
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 9785-9789
-
-
Summerer, D.1
-
54
-
-
33646038596
-
The genetic incorporation of a distance probe into proteins in Escherichia coli
-
Tsao, M.L. et al. (2006) The genetic incorporation of a distance probe into proteins in Escherichia coli. J. Am. Chem. Soc. 128, 4572-4573
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 4572-4573
-
-
Tsao, M.L.1
-
55
-
-
34547502435
-
Genetically encoding unnatural amino acids for cellular and neuronal studies
-
Wang, W. et al. (2007) Genetically encoding unnatural amino acids for cellular and neuronal studies. Nat. Neurosci. 10, 1063-1072
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1063-1072
-
-
Wang, W.1
-
56
-
-
80055007016
-
Dissecting the functions of conserved prolines within transmembrane helices of the D2 dopamine receptor
-
Van Arnam, E.B. et al. (2011) Dissecting the functions of conserved prolines within transmembrane helices of the D2 dopamine receptor. ACS Chem. Biol. 6, 1063-1068
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 1063-1068
-
-
Van Arnam, E.B.1
-
57
-
-
31544456661
-
The incorporation of a photoisomerizable amino acid into proteins in E. coli
-
Bose, M. et al. (2006) The incorporation of a photoisomerizable amino acid into proteins in E. coli. J. Am. Chem. Soc. 128, 388-389
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 388-389
-
-
Bose, M.1
-
58
-
-
0037021352
-
In vivo photocrosslinking with unnatural amino acid mutagenesis
-
Chin, J.W. and Schultz, P.G. (2002) In vivo photocrosslinking with unnatural amino acid mutagenesis. Chembiochem 3, 1135-1137
-
(2002)
Chembiochem
, vol.3
, pp. 1135-1137
-
-
Chin, J.W.1
Schultz, P.G.2
-
59
-
-
10044288227
-
Site-specific incorporation of the mucin-type Nacetylgalactosamine-a-O- threonine into protein in Escherichia coli
-
Xu, R. et al. (2004) Site-specific incorporation of the mucin-type Nacetylgalactosamine-a-O-threonine into protein in Escherichia coli. J. Am. Chem. Soc. 126, 15654-15655
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 15654-15655
-
-
Xu, R.1
-
60
-
-
33846809165
-
Site-specific incorporation of a 19F-amino acid into proteins as an NMR probe for characterizing protein structure and reactivity
-
Jackson, J.C. et al. (2007) Site-specific incorporation of a 19F-amino acid into proteins as an NMR probe for characterizing protein structure and reactivity. J. Am. Chem. Soc. 129, 1160-1166
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 1160-1166
-
-
Jackson, J.C.1
|