-
1
-
-
0034092634
-
International union of pharmacology. XXII. Nomenclature for chemokine receptors
-
Murphy, P.M. et al. (2000) International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52, 145-176
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 145-176
-
-
Murphy, P.M.1
-
2
-
-
0034144269
-
Chemokines: A new classification system and their role in immunity
-
Zlotnik, A. and Yoshie, O. (2000) Chemokines: a new classification system and their role in immunity. Immunity 12, 121-127
-
(2000)
Immunity
, vol.12
, pp. 121-127
-
-
Zlotnik, A.1
Yoshie, O.2
-
3
-
-
2542428442
-
Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells
-
Rot, A. and von Andrian, U.H. (2004) Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu. Rev. Immunol. 22, 891-928
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 891-928
-
-
Rot, A.1
Von Andrian, U.H.2
-
4
-
-
27144517061
-
CXC chemokines in angiogenesis
-
Strieter, R.M. et al. (2005) CXC chemokines in angiogenesis. Cytokine Growth Factor Rev. 16, 593-609
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 593-609
-
-
Strieter, R.M.1
-
5
-
-
53749083136
-
Regulation of chemokine activity by posttranslational modification
-
Mortier, A. et al. (2008) Regulation of chemokine activity by posttranslational modification. Pharmacol. Ther. 120, 197-217
-
(2008)
Pharmacol. Ther.
, vol.120
, pp. 197-217
-
-
Mortier, A.1
-
6
-
-
79952102426
-
Effect of posttranslational processing on the in vitro and in vivo activity of chemokines
-
Mortier, A. et al. (2010) Effect of posttranslational processing on the in vitro and in vivo activity of chemokines. Exp. Cell Res. 317, 642-654
-
(2010)
Exp. Cell Res.
, vol.317
, pp. 642-654
-
-
Mortier, A.1
-
7
-
-
43049107148
-
Proteolytic processing of chemokines: Implications in physiological and pathological conditions
-
Wolf, M. et al. (2008) Proteolytic processing of chemokines: implications in physiological and pathological conditions. Int. J. Biochem. Cell Biol. 40, 1185-1198
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 1185-1198
-
-
Wolf, M.1
-
8
-
-
34249072821
-
Transmembrane chemokines: Versatile 'special agents' in vascular inflammation
-
Ludwig, A. and Weber, C. (2007) Transmembrane chemokines: versatile 'special agents' in vascular inflammation. Thromb. Haemost. 97, 694-703
-
(2007)
Thromb. Haemost.
, vol.97
, pp. 694-703
-
-
Ludwig, A.1
Weber, C.2
-
9
-
-
65949098671
-
Chapter 1. Isolation, identification, and production of posttranslationally modified chemokines
-
Loos, T. et al. (2009) Chapter 1. Isolation, identification, and production of posttranslationally modified chemokines. Methods Enzymol. 461, 3-29
-
(2009)
Methods Enzymol
, vol.461
, pp. 3-29
-
-
Loos, T.1
-
10
-
-
53449087927
-
Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: A naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation
-
Loos, T. et al. (2008) Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation. Blood 112, 2648-2656
-
(2008)
Blood
, vol.112
, pp. 2648-2656
-
-
Loos, T.1
-
11
-
-
51049113366
-
Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation
-
Proost, P. et al. (2008) Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation. J. Exp. Med. 205, 2085-2097
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2085-2097
-
-
Proost, P.1
-
12
-
-
0000301523
-
Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis
-
Senshu, T. et al. (1996) Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis. Biochem. Biophys. Res. Commun. 225, 712-719
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 712-719
-
-
Senshu, T.1
-
13
-
-
0021027476
-
Histidine-rich proteins (filaggrins): Structural and functional heterogeneity during epidermal differentiation
-
Harding, C.R. and Scott, I.R. (1983) Histidine-rich proteins (filaggrins): structural and functional heterogeneity during epidermal differentiation. J. Mol. Biol. 170, 651-673
-
(1983)
J. Mol. Biol.
, vol.170
, pp. 651-673
-
-
Harding, C.R.1
Scott, I.R.2
-
14
-
-
0029824853
-
Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin
-
Tarcsa, E. et al. (1996) Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin. J. Biol. Chem. 271, 30709-30716
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30709-30716
-
-
Tarcsa, E.1
-
15
-
-
0037147140
-
Nuclear localization of peptidylarginine deiminase v and histone deimination in granulocytes
-
Nakashima, K. et al. (2002) Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes. J. Biol. Chem. 277, 49562-49568
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49562-49568
-
-
Nakashima, K.1
-
16
-
-
17144363594
-
Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes
-
Hagiwara, T. et al. (2005) Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes. Biochemistry 44, 5827-5834
-
(2005)
Biochemistry
, vol.44
, pp. 5827-5834
-
-
Hagiwara, T.1
-
17
-
-
0036295234
-
Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes
-
Hagiwara, T. et al. (2002) Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes. Biochem. Biophys. Res. Commun. 290, 979-983
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 979-983
-
-
Hagiwara, T.1
-
18
-
-
47949123469
-
Regulation of p53 target gene expression by peptidylarginine deiminase 4
-
Li, P. et al. (2008) Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol. Cell Biol. 28, 4745-4758
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 4745-4758
-
-
Li, P.1
-
19
-
-
49749112990
-
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis
-
Yao, H. et al. (2008) Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis. J. Biol. Chem. 283, 20060-20068
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 20060-20068
-
-
Yao, H.1
-
20
-
-
59849091593
-
Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4
-
Struyf, S. et al. (2009) Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4. J. Immunol. 182, 666-674
-
(2009)
J. Immunol.
, vol.182
, pp. 666-674
-
-
Struyf, S.1
-
21
-
-
70349636703
-
Citrullination of CXCL8 increases this chemokine's ability to mobilize neutrophils into the blood circulation
-
Loos, T. et al. (2009) Citrullination of CXCL8 increases this chemokine's ability to mobilize neutrophils into the blood circulation. Haematologica 94, 1346-1353
-
(2009)
Haematologica
, vol.94
, pp. 1346-1353
-
-
Loos, T.1
-
22
-
-
77956899749
-
Posttranslational modification of the NH2-terminal region of CXCL5 by proteases or peptidylarginine deiminases (PAD) differently affects its biological activity
-
Mortier, A. et al. (2010) Posttranslational modification of the NH2-terminal region of CXCL5 by proteases or peptidylarginine deiminases (PAD) differently affects its biological activity. J. Biol. Chem. 285, 29750-29759
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 29750-29759
-
-
Mortier, A.1
-
23
-
-
77956245423
-
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
-
Li, P. et al. (2010) PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J. Exp. Med. 207, 1853-1862
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1853-1862
-
-
Li, P.1
-
24
-
-
60849099332
-
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
-
Wang, Y. et al. (2009) Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J. Cell Biol. 184, 205-213
-
(2009)
J. Cell Biol.
, vol.184
, pp. 205-213
-
-
Wang, Y.1
-
25
-
-
33750957133
-
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: A role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation
-
Mastronardi, F.G. et al. (2006) Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J. Neurosci. 26, 11387-11396
-
(2006)
J. Neurosci.
, vol.26
, pp. 11387-11396
-
-
Mastronardi, F.G.1
-
26
-
-
20244368810
-
Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease
-
Ishigami, A. et al. (2005) Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. J. Neurosci. Res. 80, 120-128
-
(2005)
J. Neurosci. Res.
, vol.80
, pp. 120-128
-
-
Ishigami, A.1
-
27
-
-
33745650746
-
Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis
-
Bhattacharya, S.K. et al. (2006) Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis. Invest Ophthalmol. Vis. Sci. 47, 2508-2514
-
(2006)
Invest Ophthalmol. Vis. Sci.
, vol.47
, pp. 2508-2514
-
-
Bhattacharya, S.K.1
-
28
-
-
77449101433
-
Involvement of peptidylarginine deiminasemediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease
-
Jang, B. et al. (2010) Involvement of peptidylarginine deiminasemediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease. Acta Neuropathol. 119, 199-210
-
(2010)
Acta Neuropathol
, vol.119
, pp. 199-210
-
-
Jang, B.1
-
29
-
-
79959508911
-
PADI4 and tumourigenesis
-
Chang, X. and Fang, K. (2010) PADI4 and tumourigenesis. Cancer Cell Int. 10, 7
-
(2010)
Cancer Cell Int
, vol.10
, pp. 7
-
-
Chang, X.1
Fang, K.2
-
30
-
-
27744515706
-
Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
-
Lundberg, K. et al. (2005) Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity. Arthritis Res. Ther. 7, R458-R467
-
(2005)
Arthritis Res. Ther.
, vol.7
-
-
Lundberg, K.1
-
31
-
-
28744455086
-
Almost all about citrulline in mammals
-
Curis, E. et al. (2005) Almost all about citrulline in mammals. Amino Acids 29, 177-205
-
(2005)
Amino Acids
, vol.29
, pp. 177-205
-
-
Curis, E.1
-
32
-
-
34249818191
-
Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling
-
Mori, M. (2007) Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling. J. Nutr. 137, 1616S-1620S
-
(2007)
J. Nutr.
, vol.137
-
-
Mori, M.1
-
33
-
-
0000190904
-
The carbamido diacetyl reaction: A test for citrulline
-
Fearon, W.R. (1939) The carbamido diacetyl reaction: a test for citrulline. Biochem. J. 33, 902-907
-
(1939)
Biochem. J.
, vol.33
, pp. 902-907
-
-
Fearon, W.R.1
-
34
-
-
70449228961
-
Amino acids, peptides, and proteins of Irish Moss, Chondrus crispus
-
Young, E.G. and Smith, D.G. (1958) Amino acids, peptides, and proteins of Irish Moss, Chondrus crispus. J. Biol. Chem. 233, 406-410
-
(1958)
J. Biol. Chem.
, vol.233
, pp. 406-410
-
-
Young, E.G.1
Smith, D.G.2
-
35
-
-
0000149418
-
Occurrence of citrulline in proteins
-
Rogers, G.E. (1962) Occurrence of citrulline in proteins. Nature 194, 1149-1151
-
(1962)
Nature
, vol.194
, pp. 1149-1151
-
-
Rogers, G.E.1
-
36
-
-
0017351552
-
The enzymic derivation of citrulline residues from arginine residues in situ during the biosynthesis of hair proteins that are cross-linked by isopeptide bonds
-
Rogers, G.E. and Taylor, L.D. (1977) The enzymic derivation of citrulline residues from arginine residues in situ during the biosynthesis of hair proteins that are cross-linked by isopeptide bonds. Adv. Exp. Med. Biol. 86A, 283-294
-
(1977)
Adv. Exp. Med. Biol.
, vol.86 A
, pp. 283-294
-
-
Rogers, G.E.1
Taylor, L.D.2
-
37
-
-
0019436684
-
Properties of peptidylarginine deiminase from the epidermis of newborn rats
-
Fujisaki, M. and Sugawara, K. (1981) Properties of peptidylarginine deiminase from the epidermis of newborn rats. J. Biochem. 89, 257-263
-
(1981)
J. Biochem.
, vol.89
, pp. 257-263
-
-
Fujisaki, M.1
Sugawara, K.2
-
38
-
-
0026603902
-
Specificity and mode of action of the muscle-type protein-arginine deiminase
-
Nomura, K. (1992) Specificity and mode of action of the muscle-type protein-arginine deiminase. Arch. Biochem. Biophys. 293, 362-369
-
(1992)
Arch. Biochem. Biophys.
, vol.293
, pp. 362-369
-
-
Nomura, K.1
-
39
-
-
84860390022
-
Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: Novel insights into autoantigen selection in rheumatoid arthritis
-
Darrah, E. et al. (2011) Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis. Ann. Rheum. Dis. 71, 92-98
-
(2011)
Ann. Rheum. Dis.
, vol.71
, pp. 92-98
-
-
Darrah, E.1
-
40
-
-
19944417554
-
Comparison of enzymatic properties between hPADI2 and hPADI4
-
Nakayama-Hamada, M. et al. (2005) Comparison of enzymatic properties between hPADI2 and hPADI4. Biochem. Biophys. Res. Commun. 327, 192-200
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.327
, pp. 192-200
-
-
Nakayama-Hamada, M.1
-
41
-
-
0242720407
-
PAD, a growing family of citrullinating enzymes: Genes, features and involvement in disease
-
Vossenaar, E.R. et al. (2003) PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease. Bioessays 25, 1106-1118
-
(2003)
Bioessays
, vol.25
, pp. 1106-1118
-
-
Vossenaar, E.R.1
-
42
-
-
0033004481
-
Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase
-
McGraw, W.T. et al. (1999) Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase. Infect. Immun. 67, 3248-3256
-
(1999)
Infect. Immun.
, vol.67
, pp. 3248-3256
-
-
McGraw, W.T.1
-
43
-
-
53349090275
-
Arginine deiminase has multiple regulatory roles in the biology of Giardia lamblia
-
Touz, M.C. et al. (2008) Arginine deiminase has multiple regulatory roles in the biology of Giardia lamblia. J. Cell Sci. 121, 2930-2938
-
(2008)
J. Cell Sci.
, vol.121
, pp. 2930-2938
-
-
Touz, M.C.1
-
44
-
-
0037442843
-
CDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type i
-
Guerrin, M. et al. (2003) cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I. Biochem. J. 370, 167-174
-
(2003)
Biochem. J.
, vol.370
, pp. 167-174
-
-
Guerrin, M.1
-
45
-
-
33749327922
-
Peptidylarginine deiminases and deimination in biology and pathology: Relevance to skin homeostasis
-
Chavanas, S. et al. (2006) Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis. J. Dermatol. Sci. 44, 63-72
-
(2006)
J. Dermatol. Sci.
, vol.44
, pp. 63-72
-
-
Chavanas, S.1
-
46
-
-
1842829046
-
Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved noncoding segments and a new human gene, PADI6
-
Chavanas, S. et al. (2004) Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved noncoding segments and a new human gene, PADI6. Gene 330, 19-27
-
(2004)
Gene
, vol.330
, pp. 19-27
-
-
Chavanas, S.1
-
47
-
-
0036406870
-
Human peptidylarginine deiminase type II: Molecular cloning, gene organization, and expression in human skin
-
Ishigami, A. et al. (2002) Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin. Arch. Biochem. Biophys. 407, 25-31
-
(2002)
Arch. Biochem. Biophys.
, vol.407
, pp. 25-31
-
-
Ishigami, A.1
-
48
-
-
27844536541
-
A rigorous method for multigenic families' functional annotation: The peptidyl arginine deiminase (PADs) proteins family example
-
Balandraud, N. et al. (2005) A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example. BMC Genomics 6, 153
-
(2005)
BMC Genomics
, vol.6
, pp. 153
-
-
Balandraud, N.1
-
49
-
-
0024281847
-
Combined biochemical and immunochemical comparison of peptidylarginine deiminases present in various tissues
-
Watanabe, K. et al. (1988) Combined biochemical and immunochemical comparison of peptidylarginine deiminases present in various tissues. Biochim. Biophys. Acta 966, 375-383
-
(1988)
Biochim. Biophys. Acta
, vol.966
, pp. 375-383
-
-
Watanabe, K.1
-
50
-
-
0024430819
-
Isolation and characterization of cDNA clones encoding rat skeletal muscle peptidylarginine deiminase
-
Watanabe, K. and Senshu, T. (1989) Isolation and characterization of cDNA clones encoding rat skeletal muscle peptidylarginine deiminase. J. Biol. Chem. 264, 15255-15260
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 15255-15260
-
-
Watanabe, K.1
Senshu, T.2
-
51
-
-
0033749775
-
Human peptidylarginine deiminase type III: Molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin
-
Kanno, T. et al. (2000) Human peptidylarginine deiminase type III: molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin. J. Invest. Dermatol. 115, 813-823
-
(2000)
J. Invest. Dermatol.
, vol.115
, pp. 813-823
-
-
Kanno, T.1
-
52
-
-
0032575260
-
Cloning of cDNA encoding a novel isoform (type IV) of peptidylarginine deiminase from rat epidermis
-
Yamakoshi, A. et al. (1998) Cloning of cDNA encoding a novel isoform (type IV) of peptidylarginine deiminase from rat epidermis. Biochim. Biophys. Acta 1386, 227-232
-
(1998)
Biochim. Biophys. Acta
, vol.1386
, pp. 227-232
-
-
Yamakoshi, A.1
-
53
-
-
0031812033
-
Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid-treated culture of a newborn rat keratinocyte cell line
-
Ishigami, A. et al. (1998) Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid-treated culture of a newborn rat keratinocyte cell line. FEBS Lett. 433, 113-118
-
(1998)
FEBS Lett
, vol.433
, pp. 113-118
-
-
Ishigami, A.1
-
54
-
-
0034968874
-
Immunocytochemical localization of peptidylarginine deiminase in human eosinophils and neutrophils
-
Asaga, H. et al. (2001) Immunocytochemical localization of peptidylarginine deiminase in human eosinophils and neutrophils. J. Leukoc. Biol. 70, 46-51
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 46-51
-
-
Asaga, H.1
-
55
-
-
0033600723
-
Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)
-
Nakashima, K. et al. (1999) Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3). J. Biol. Chem. 274, 27786-27792
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27786-27792
-
-
Nakashima, K.1
-
56
-
-
19944433096
-
CDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type VI
-
Zhang, J. et al. (2004) cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type VI. Acta Biochim. Pol. 51, 1051-1058
-
(2004)
Acta Biochim. Pol.
, vol.51
, pp. 1051-1058
-
-
Zhang, J.1
-
57
-
-
27344455003
-
Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development
-
Liu, M. et al. (2005) Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development. Reprod. Biol. Endocrinol. 3, 42
-
(2005)
Reprod. Biol. Endocrinol.
, vol.3
, pp. 42
-
-
Liu, M.1
-
58
-
-
79251595796
-
Subcellular localization of peptidylarginine deiminase 2 and citrullinated proteins in brains of scrapie-infected mice: Nuclear localization of PAD2 and membrane fraction-enriched citrullinated proteins
-
Jang, B. et al. (2011) Subcellular localization of peptidylarginine deiminase 2 and citrullinated proteins in brains of scrapie-infected mice: nuclear localization of PAD2 and membrane fraction-enriched citrullinated proteins. J. Neuropathol. Exp. Neurol. 70, 116-124
-
(2011)
J. Neuropathol. Exp. Neurol.
, vol.70
, pp. 116-124
-
-
Jang, B.1
-
59
-
-
39149089293
-
Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type i gene (PADI1) in human keratinocytes
-
Dong, S. et al. (2008) Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes. J. Invest. Dermatol. 128, 549-557
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 549-557
-
-
Dong, S.1
-
60
-
-
34347241381
-
Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alpha-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1
-
Dong, S. et al. (2007) Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alpha-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1. Mol. Endocrinol. 21, 1617-1629
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 1617-1629
-
-
Dong, S.1
-
61
-
-
33746881392
-
NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes
-
Dong, S. et al. (2006) NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes. Biochem. J. 397, 449-459
-
(2006)
Biochem. J.
, vol.397
, pp. 449-459
-
-
Dong, S.1
-
62
-
-
18244363581
-
Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors
-
Dong, S. et al. (2005) Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors. J. Invest. Dermatol. 124, 1026-1033
-
(2005)
J. Invest. Dermatol.
, vol.124
, pp. 1026-1033
-
-
Dong, S.1
-
63
-
-
4444372638
-
Histone deimination antagonizes arginine methylation
-
Cuthbert, G.L. et al. (2004) Histone deimination antagonizes arginine methylation. Cell 118, 545-553
-
(2004)
Cell
, vol.118
, pp. 545-553
-
-
Cuthbert, G.L.1
-
64
-
-
34447334574
-
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated
-
Mastronardi, F.G. et al. (2007) Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J. Neurosci. Res. 85, 2006-2016
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 2006-2016
-
-
Mastronardi, F.G.1
-
65
-
-
16844378742
-
Transcriptional profiling of keratinocytes reveals a vitamin D-regulated epidermal differentiation network
-
Lu, J. et al. (2005) Transcriptional profiling of keratinocytes reveals a vitamin D-regulated epidermal differentiation network. J. Invest. Dermatol. 124, 778-785
-
(2005)
J. Invest. Dermatol.
, vol.124
, pp. 778-785
-
-
Lu, J.1
-
66
-
-
77952920098
-
Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation
-
Andrade, F. et al. (2010) Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation. Arthritis Rheum. 62, 1630-1640
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1630-1640
-
-
Andrade, F.1
-
67
-
-
77952307740
-
Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases
-
Mechin, M.C. et al. (2010) Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases. Cell Mol. Life Sci. 67, 1491-1503
-
(2010)
Cell Mol. Life Sci.
, vol.67
, pp. 1491-1503
-
-
Mechin, M.C.1
-
68
-
-
79955828498
-
Autodeimination of protein arginine deiminase 4 alters protein-protein interactions but not activity
-
Slack, J.L. et al. (2011) Autodeimination of protein arginine deiminase 4 alters protein-protein interactions but not activity. Biochemistry 50, 3997-4010
-
(2011)
Biochemistry
, vol.50
, pp. 3997-4010
-
-
Slack, J.L.1
-
69
-
-
79959461857
-
Functional role of dimerization of human peptidylarginine deiminase 4 (PAD4)
-
Liu, Y.L. et al. (2011) Functional role of dimerization of human peptidylarginine deiminase 4 (PAD4). PLoS ONE 6, e21314
-
(2011)
PLoS ONE
, vol.6
-
-
Liu, Y.L.1
-
70
-
-
31944448153
-
A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation
-
Luo, Y. et al. (2006) A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation. J. Am. Chem. Soc. 128, 1092-1093
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 1092-1093
-
-
Luo, Y.1
-
71
-
-
0032517246
-
A novel microtubule independent effect of paclitaxel: The inhibition of peptidylarginine deiminase from bovine brain
-
Pritzker, L.B. and Moscarello, M.A. (1998) A novel microtubule independent effect of paclitaxel: the inhibition of peptidylarginine deiminase from bovine brain. Biochim. Biophys. Acta 1388, 154-160
-
(1998)
Biochim. Biophys. Acta
, vol.1388
, pp. 154-160
-
-
Pritzker, L.B.1
Moscarello, M.A.2
-
72
-
-
27144463085
-
Inactivation of two diverse enzymes in the amidinotransferase superfamily by 2-chloroacetamidine: Dimethylargininase and peptidylarginine deiminase
-
Stone, E.M. et al. (2005) Inactivation of two diverse enzymes in the amidinotransferase superfamily by 2-chloroacetamidine: dimethylargininase and peptidylarginine deiminase. Biochemistry 44, 13744-13752
-
(2005)
Biochemistry
, vol.44
, pp. 13744-13752
-
-
Stone, E.M.1
-
73
-
-
33749359452
-
Inhibitors and inactivators of protein arginine deiminase 4: Functional and structural characterization
-
Luo, Y. et al. (2006) Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization. Biochemistry 45, 11727-11736
-
(2006)
Biochemistry
, vol.45
, pp. 11727-11736
-
-
Luo, Y.1
-
74
-
-
79955006474
-
N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)-Lornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis
-
Willis, V.C. et al. (2011) N-alpha-benzoyl-N5-(2-chloro-1-iminoethyl)- Lornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. J. Immunol. 186, 4396-4404
-
(2011)
J. Immunol.
, vol.186
, pp. 4396-4404
-
-
Willis, V.C.1
-
75
-
-
79957951714
-
Suppression of colitis in mice by Clamidine: A novel peptidylarginine deiminase inhibitor
-
Chumanevich, A.A. et al. (2011) Suppression of colitis in mice by Clamidine: a novel peptidylarginine deiminase inhibitor. Am. J. Physiol. Gastrointest. Liver Physiol. 300, G929-G938
-
(2011)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.300
-
-
Chumanevich, A.A.1
-
76
-
-
77953258110
-
Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3
-
Knuckley, B. et al. (2010) Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry 49, 4852-4863
-
(2010)
Biochemistry
, vol.49
, pp. 4852-4863
-
-
Knuckley, B.1
-
77
-
-
33751010478
-
Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): Synthesis and in vitro evaluation of a fluorescently labeled probe
-
Luo, Y. et al. (2006) Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe. J. Am. Chem. Soc. 128, 14468-14469
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 14468-14469
-
-
Luo, Y.1
-
78
-
-
38549168544
-
Profiling protein arginine deiminase 4 (PAD4): A novel screen to identify PAD4 inhibitors
-
Knuckley, B. et al. (2008) Profiling protein arginine deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors. Bioorg. Med. Chem. 16, 739-745
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 739-745
-
-
Knuckley, B.1
-
79
-
-
80053903112
-
The development of N-alpha-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1- iminoethyl)-L-ornithine amide (o-Famidine) and N-alpha-(2-carboxyl)benzoyl-N(5)- (2-chloro-1-iminoethyl)-L-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors
-
Causey, C.P. et al. (2011) The development of N-alpha-(2-carboxyl) benzoyl-N(5)-(2-fluoro-1-iminoethyl)-L-ornithine amide (o-Famidine) and N-alpha-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-L-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. J. Med. Chem. 54, 6919-6935
-
(2011)
J. Med. Chem.
, vol.54
, pp. 6919-6935
-
-
Causey, C.P.1
-
80
-
-
84862945967
-
Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors
-
Jones, J.E. et al. (2012) Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem. Biol. 7, 160-165
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 160-165
-
-
Jones, J.E.1
-
81
-
-
77956829294
-
A fluopol-ABPP HTS assay to identify PAD inhibitors
-
Knuckley, B. et al. (2010) A fluopol-ABPP HTS assay to identify PAD inhibitors. Chem. Commun. (Camb.) 46, 7175-7177
-
(2010)
Chem. Commun. (Camb.)
, vol.46
, pp. 7175-7177
-
-
Knuckley, B.1
-
82
-
-
34648844365
-
Design of ENA gapmers as fine-tuning antisense oligonucleotides with sequence-specific inhibitory activity on mouse PADI4 mRNA expression
-
Takagi-Sato, M. et al. (2006) Design of ENA gapmers as fine-tuning antisense oligonucleotides with sequence-specific inhibitory activity on mouse PADI4 mRNA expression. Nucleic Acids Symp. Ser. (Oxf.) 319-320
-
(2006)
Nucleic Acids Symp. Ser. (Oxf.)
, pp. 319-320
-
-
Takagi-Sato, M.1
-
83
-
-
34648830157
-
Fine-tuning of ENA gapmers as antisense oligonucleotides for sequence-specific inhibition
-
Takagi-Sato, M. et al. (2007) Fine-tuning of ENA gapmers as antisense oligonucleotides for sequence-specific inhibition. Oligonucleotides 17, 291-301
-
(2007)
Oligonucleotides
, vol.17
, pp. 291-301
-
-
Takagi-Sato, M.1
-
84
-
-
70350304571
-
Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities
-
Yu, J.T. et al. (2009) Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities. Prog. Neurobiol. 89, 240-255
-
(2009)
Prog. Neurobiol.
, vol.89
, pp. 240-255
-
-
Yu, J.T.1
-
85
-
-
0007494230
-
The localization and significance of arginine and citrulline in proteins of the hair follicle
-
Rogers, G.E. (1963) The localization and significance of arginine and citrulline in proteins of the hair follicle. J. Histochem. Cytochem. 11, 700-705
-
(1963)
J. Histochem. Cytochem.
, vol.11
, pp. 700-705
-
-
Rogers, G.E.1
-
86
-
-
0030784777
-
The fate of trichohyalin. Sequential posttranslational modifications by peptidyl-arginine deiminase and transglutaminases
-
Tarcsa, E. et al. (1997) The fate of trichohyalin. Sequential posttranslational modifications by peptidyl-arginine deiminase and transglutaminases. J. Biol. Chem. 272, 27893-27901
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27893-27901
-
-
Tarcsa, E.1
-
87
-
-
22144467342
-
Peptidylarginine deiminase isoforms are differentially expressed in the anagen hair follicles and other human skin appendages
-
Nachat, R. et al. (2005) Peptidylarginine deiminase isoforms are differentially expressed in the anagen hair follicles and other human skin appendages. J. Invest. Dermatol. 125, 34-41
-
(2005)
J. Invest. Dermatol.
, vol.125
, pp. 34-41
-
-
Nachat, R.1
-
88
-
-
0030977197
-
Peptidylarginine deiminase of the hair follicle: Characterization, localization, and function in keratinizing tissues
-
Rogers, G. et al. (1997) Peptidylarginine deiminase of the hair follicle: characterization, localization, and function in keratinizing tissues. J. Invest. Dermatol. 108, 700-707
-
(1997)
J. Invest. Dermatol.
, vol.108
, pp. 700-707
-
-
Rogers, G.1
-
89
-
-
0032496154
-
Biochemical evidence that small proline-rich proteins and trichohyalin function in epithelia by modulation of the biomechanical properties of their cornified cell envelopes
-
Steinert, P.M. et al. (1998) Biochemical evidence that small proline-rich proteins and trichohyalin function in epithelia by modulation of the biomechanical properties of their cornified cell envelopes. J. Biol. Chem. 273, 11758-11769
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11758-11769
-
-
Steinert, P.M.1
-
90
-
-
36049041609
-
Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation
-
Foulquier, C. et al. (2007) Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation. Arthritis Rheum. 56, 3541-3553
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3541-3553
-
-
Foulquier, C.1
-
91
-
-
24344505085
-
The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations
-
Mechin, M.C. et al. (2005) The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations. Cell Mol. Life Sci. 62, 1984-1995
-
(2005)
Cell Mol. Life Sci.
, vol.62
, pp. 1984-1995
-
-
Mechin, M.C.1
-
92
-
-
41949092464
-
Specific citrullination causes assembly of a globular S100A3 homotetramer: A putative Ca2+ modulator matures human hair cuticle
-
Kizawa, K. et al. (2008) Specific citrullination causes assembly of a globular S100A3 homotetramer: a putative Ca2+ modulator matures human hair cuticle. J. Biol. Chem. 283, 5004-5013
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5004-5013
-
-
Kizawa, K.1
-
93
-
-
0037376592
-
EPAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets
-
Wright, P.W. et al. (2003) ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets. Dev. Biol. 256, 73-88
-
(2003)
Dev. Biol.
, vol.256
, pp. 73-88
-
-
Wright, P.W.1
-
94
-
-
0020106254
-
Identification and properties of peptidylarginine deiminase from rabbit skeletal muscle
-
Sugawara, K. et al. (1982) Identification and properties of peptidylarginine deiminase from rabbit skeletal muscle. J. Biochem. 91, 1065-1071
-
(1982)
J. Biochem.
, vol.91
, pp. 1065-1071
-
-
Sugawara, K.1
-
95
-
-
0842324785
-
The nucleosome: From genomic organization to genomic regulation
-
Khorasanizadeh, S. (2004) The nucleosome: from genomic organization to genomic regulation. Cell 116, 259-272
-
(2004)
Cell
, vol.116
, pp. 259-272
-
-
Khorasanizadeh, S.1
-
96
-
-
69549108028
-
Recognition of the N-terminal histone H2A and H3 peptides by peptidylarginine deiminase IV
-
Saiki, M. et al. (2009) Recognition of the N-terminal histone H2A and H3 peptides by peptidylarginine deiminase IV. Protein Pept. Lett. 16, 1012-1016
-
(2009)
Protein Pept. Lett.
, vol.16
, pp. 1012-1016
-
-
Saiki, M.1
-
97
-
-
5044228483
-
Human PAD4 regulates histone arginine methylation levels via demethylimination
-
Wang, Y. et al. (2004) Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306, 279-283
-
(2004)
Science
, vol.306
, pp. 279-283
-
-
Wang, Y.1
-
98
-
-
22544464445
-
Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV
-
Hidaka, Y. et al. (2005) Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV. FEBS Lett. 579, 4088-4092
-
(2005)
FEBS Lett
, vol.579
, pp. 4088-4092
-
-
Hidaka, Y.1
-
99
-
-
20744442981
-
Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells
-
Balint, B.L. et al. (2005) Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells. Mol. Cell Biol. 25, 5648-5663
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 5648-5663
-
-
Balint, B.L.1
-
100
-
-
77955862796
-
Deimination stabilizes histone H2A/H2B dimers as revealed by electrospray ionization mass spectrometry
-
Shimoyama, S. et al. (2010) Deimination stabilizes histone H2A/H2B dimers as revealed by electrospray ionization mass spectrometry. J. Mass Spectrom. 45, 900-908
-
(2010)
J. Mass Spectrom.
, vol.45
, pp. 900-908
-
-
Shimoyama, S.1
-
101
-
-
14844360649
-
Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination
-
Lee, Y.H. et al. (2005) Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination. Proc. Natl. Acad. Sci. U. S. A. 102, 3611-3616
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 3611-3616
-
-
Lee, Y.H.1
-
102
-
-
33847759102
-
Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro
-
Raijmakers, R. et al. (2007) Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro. J. Mol. Biol. 367, 1118-1129
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 1118-1129
-
-
Raijmakers, R.1
-
103
-
-
72249096427
-
Regulation of protein Citrullination through p53/PADI4 network in DNA damage response
-
Tanikawa, C. et al. (2009) Regulation of protein Citrullination through p53/PADI4 network in DNA damage response. Cancer Res. 69, 8761-8769
-
(2009)
Cancer Res
, vol.69
, pp. 8761-8769
-
-
Tanikawa, C.1
-
104
-
-
79959269919
-
Discovery of peptidylarginine deiminase-4 substrates by protein array: Antagonistic citrullination and methylation of human ribosomal protein S2
-
Guo, Q. et al. (2011) Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2. Mol. Biosyst. 7, 2286-2295
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 2286-2295
-
-
Guo, Q.1
-
105
-
-
79955765048
-
Citrullination of inhibitor of growth 4 (ING4) by peptidylarginine deminase 4 (PAD4) disrupts the interaction between ING4 and p53
-
Guo, Q. and Fast, W. (2011) Citrullination of inhibitor of growth 4 (ING4) by peptidylarginine deminase 4 (PAD4) disrupts the interaction between ING4 and p53. J. Biol. Chem. 286, 17069-17078
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17069-17078
-
-
Guo, Q.1
Fast, W.2
-
106
-
-
0034080318
-
The biology of chemokines and their receptors
-
Rossi, D. and Zlotnik, A. (2000) The biology of chemokines and their receptors. Annu. Rev. Immunol. 18, 217-242
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 217-242
-
-
Rossi, D.1
Zlotnik, A.2
-
107
-
-
27144468308
-
Interaction of chemokines and glycosaminoglycans: A new twist in the regulation of chemokine function with opportunities for therapeutic intervention
-
Johnson, Z. et al. (2005) Interaction of chemokines and glycosaminoglycans: a new twist in the regulation of chemokine function with opportunities for therapeutic intervention. Cytokine Growth Factor Rev. 16, 625-636
-
(2005)
Cytokine Growth Factor Rev.
, vol.16
, pp. 625-636
-
-
Johnson, Z.1
-
108
-
-
80052321311
-
Biological activity of CXCL8 forms generated by alternative cleavage of the signal peptide or by aminopeptidase-mediated truncation
-
Mortier, A. et al. (2011) Biological activity of CXCL8 forms generated by alternative cleavage of the signal peptide or by aminopeptidase-mediated truncation. PLoS ONE 6, e23913
-
(2011)
PLoS ONE
, vol.6
-
-
Mortier, A.1
-
109
-
-
83455221107
-
Detection and quantification of citrullinated chemokines
-
Moelants, E.A.V. et al. (2011) Detection and quantification of citrullinated chemokines. PLoS ONE 6, e28976
-
(2011)
PLoS ONE
, vol.6
-
-
Moelants, E.A.V.1
-
110
-
-
0033647240
-
The neutrophil as a cellular source of chemokines
-
Scapini, P. et al. (2000) The neutrophil as a cellular source of chemokines. Immunol. Rev. 177, 195-203
-
(2000)
Immunol. Rev.
, vol.177
, pp. 195-203
-
-
Scapini, P.1
-
111
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann, V. et al. (2004) Neutrophil extracellular traps kill bacteria. Science 303, 1532-1535
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
-
112
-
-
34248524638
-
Unconventional roles of the NADPH oxidase: Signaling, ion homeostasis, and cell death
-
Steinberg, B.E. and Grinstein, S. (2007) Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death. Sci. STKE 379, pe11
-
(2007)
Sci. STKE
, vol.379
-
-
Steinberg, B.E.1
Grinstein, S.2
-
113
-
-
79952622190
-
Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality
-
Remijsen, Q. et al. (2011) Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality. Cell Death Differ. 18, 581-588
-
(2011)
Cell Death Differ
, vol.18
, pp. 581-588
-
-
Remijsen, Q.1
-
114
-
-
40749128547
-
Histone deimination as a response to inflammatory stimuli in neutrophils
-
Neeli, I. et al. (2008) Histone deimination as a response to inflammatory stimuli in neutrophils. J. Immunol. 180, 1895-1902
-
(2008)
J. Immunol.
, vol.180
, pp. 1895-1902
-
-
Neeli, I.1
-
115
-
-
67349279881
-
Netting neutrophils in autoimmune smallvessel vasculitis
-
Kessenbrock, K. et al. (2009) Netting neutrophils in autoimmune smallvessel vasculitis. Nat. Med. 15, 623-625
-
(2009)
Nat. Med.
, vol.15
, pp. 623-625
-
-
Kessenbrock, K.1
-
116
-
-
77953088427
-
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
-
Hakkim, A. et al. (2010) Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc. Natl. Acad. Sci. U. S. A. 107, 9813-9818
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 9813-9818
-
-
Hakkim, A.1
-
117
-
-
0034003263
-
Decreased deiminated keratin K1 in psoriatic hyperproliferative epidermis
-
Ishida-Yamamoto, A. et al. (2000) Decreased deiminated keratin K1 in psoriatic hyperproliferative epidermis. J. Invest. Dermatol. 114, 701-705
-
(2000)
J. Invest. Dermatol.
, vol.114
, pp. 701-705
-
-
Ishida-Yamamoto, A.1
-
118
-
-
79960823772
-
Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice
-
Coudane, F. et al. (2011) Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice. Eur. J. Dermatol. 21, 376-384
-
(2011)
Eur. J. Dermatol.
, vol.21
, pp. 376-384
-
-
Coudane, F.1
-
119
-
-
53149091632
-
Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapieinfected mice: A possible role in pathogenesis
-
Jang, B. et al. (2008) Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapieinfected mice: a possible role in pathogenesis. Am. J. Pathol. 173, 1129-1142
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 1129-1142
-
-
Jang, B.1
-
120
-
-
0024567052
-
The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein
-
Wood, D.D. and Moscarello, M.A. (1989) The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein. J. Biol. Chem. 264, 5121-5127
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 5121-5127
-
-
Wood, D.D.1
Moscarello, M.A.2
-
121
-
-
0028342830
-
Myelin in multiple sclerosis is developmentally immature
-
Moscarello, M.A. et al. (1994) Myelin in multiple sclerosis is developmentally immature. J. Clin. Invest. 94, 146-154
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 146-154
-
-
Moscarello, M.A.1
-
122
-
-
0029927069
-
Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein
-
Wood, D.D. et al. (1996) Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein. Ann. Neurol. 40, 18-24
-
(1996)
Ann. Neurol.
, vol.40
, pp. 18-24
-
-
Wood, D.D.1
-
123
-
-
0034625091
-
Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D
-
Pritzker, L.B. et al. (2000) Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D. Biochemistry 39, 5374-5381
-
(2000)
Biochemistry
, vol.39
, pp. 5374-5381
-
-
Pritzker, L.B.1
-
124
-
-
33645210449
-
Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope
-
Musse, A.A. et al. (2006) Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope. Proc. Natl. Acad. Sci. U. S. A. 103, 4422-4427
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4422-4427
-
-
Musse, A.A.1
-
125
-
-
0034625146
-
Deimination of myelin basic protein. 2. Effect of methylation of MBP on its deimination by peptidylarginine deiminase
-
Pritzker, L.B. et al. (2000) Deimination of myelin basic protein. 2. Effect of methylation of MBP on its deimination by peptidylarginine deiminase. Biochemistry 39, 5382-5388
-
(2000)
Biochemistry
, vol.39
, pp. 5382-5388
-
-
Pritzker, L.B.1
-
126
-
-
38149063361
-
Expression pattern of peptidylarginine deiminase in rat and human Schwann cells
-
Keilhoff, G. et al. (2008) Expression pattern of peptidylarginine deiminase in rat and human Schwann cells. Dev. Neurobiol. 68, 101-114
-
(2008)
Dev. Neurobiol.
, vol.68
, pp. 101-114
-
-
Keilhoff, G.1
-
127
-
-
41149143688
-
Myelin localization of peptidylarginine deiminases 2 and 4: Comparison of PAD2 and PAD4 activities
-
Wood, D.D. et al. (2008) Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities. Lab. Invest. 88, 354-364
-
(2008)
Lab. Invest.
, vol.88
, pp. 354-364
-
-
Wood, D.D.1
-
128
-
-
0033593458
-
Peptidylarginine deiminase activity in postmortem white matter of patients with multiple sclerosis
-
De Keyser, J. et al. (1999) Peptidylarginine deiminase activity in postmortem white matter of patients with multiple sclerosis. Neurosci. Lett. 260, 74-76
-
(1999)
Neurosci. Lett.
, vol.260
, pp. 74-76
-
-
De Keyser, J.1
-
129
-
-
17844411445
-
Expression of citrullinated proteins in murineexperimentalautoimmune encephalomyelitis
-
Nicholas, A.P. et al. (2005) Expression of citrullinated proteins in murineexperimentalautoimmune encephalomyelitis. J. Comp. Neurol. 486, 254-266
-
(2005)
J. Comp. Neurol.
, vol.486
, pp. 254-266
-
-
Nicholas, A.P.1
-
130
-
-
1942452851
-
Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis
-
Nicholas, A.P. et al. (2004) Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis. J. Comp. Neurol. 473, 128-136
-
(2004)
J. Comp. Neurol.
, vol.473
, pp. 128-136
-
-
Nicholas, A.P.1
-
131
-
-
33746844946
-
Experimental autoimmune encephalomyelitis induction in peptidylarginine deiminase 2 knockout mice
-
Raijmakers, R. et al. (2006) Experimental autoimmune encephalomyelitis induction in peptidylarginine deiminase 2 knockout mice. J. Comp. Neurol. 498, 217-226
-
(2006)
J. Comp. Neurol.
, vol.498
, pp. 217-226
-
-
Raijmakers, R.1
-
132
-
-
0024473081
-
Ca2+-dependent deimination-induced disassembly of intermediate filaments involves specific modification of the amino-terminal head domain
-
Inagaki, M. et al. (1989) Ca2+-dependent deimination-induced disassembly of intermediate filaments involves specific modification of the amino-terminal head domain. J. Biol. Chem. 264, 18119-18127
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 18119-18127
-
-
Inagaki, M.1
-
133
-
-
0030046508
-
Life, death, and the pursuit of apoptosis
-
White, E. (1996) Life, death, and the pursuit of apoptosis. Genes Dev. 10, 1-15
-
(1996)
Genes Dev
, vol.10
, pp. 1-15
-
-
White, E.1
-
134
-
-
12344327644
-
Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis
-
Chang, X. et al. (2005) Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis. Rheumatology (Oxford) 44, 40-50
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 40-50
-
-
Chang, X.1
-
135
-
-
33344477322
-
Overexpression of peptidylarginine deiminase IV features in apoptosis of haematopoietic cells
-
Liu, G.Y. et al. (2006) Overexpression of peptidylarginine deiminase IV features in apoptosis of haematopoietic cells. Apoptosis 11, 183-196
-
(2006)
Apoptosis
, vol.11
, pp. 183-196
-
-
Liu, G.Y.1
-
136
-
-
79951578893
-
Protein arginine deiminase 4: A target for an epigenetic cancer therapy
-
Slack, J.L. et al. (2011) Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cell Mol. Life Sci. 68, 709-720
-
(2011)
Cell Mol. Life Sci.
, vol.68
, pp. 709-720
-
-
Slack, J.L.1
-
137
-
-
29844446754
-
Use and significance of anti-CCP autoantibodies in rheumatoid arthritis
-
Zendman, A.J. et al. (2006) Use and significance of anti-CCP autoantibodies in rheumatoid arthritis. Rheumatology (Oxford) 45, 20-25
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 20-25
-
-
Zendman, A.J.1
-
138
-
-
7644238939
-
Autoantibodies to citrullinated proteins in rheumatoid arthritis: Clinical performance and biochemical aspects of an RA-specific marker
-
Nijenhuis, S. et al. (2004) Autoantibodies to citrullinated proteins in rheumatoid arthritis: clinical performance and biochemical aspects of an RA-specific marker. Clin. Chim. Acta 350, 17-34
-
(2004)
Clin. Chim. Acta
, vol.350
, pp. 17-34
-
-
Nijenhuis, S.1
-
139
-
-
0035883897
-
Rheumatoid arthritis
-
Lee, D.M. and Weinblatt, M.E. (2001) Rheumatoid arthritis. Lancet 358, 903-911
-
(2001)
Lancet
, vol.358
, pp. 903-911
-
-
Lee, D.M.1
Weinblatt, M.E.2
-
140
-
-
17744377384
-
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset
-
Goldbach-Mansky, R. et al. (2000) Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset. Arthritis Res. 2, 236-243
-
(2000)
Arthritis Res
, vol.2
, pp. 236-243
-
-
Goldbach-Mansky, R.1
-
141
-
-
17144375677
-
Rheumatoid factor on a daily basis
-
Renaudineau, Y. et al. (2005) Rheumatoid factor on a daily basis. Autoimmunity 38, 11-16
-
(2005)
Autoimmunity
, vol.38
, pp. 11-16
-
-
Renaudineau, Y.1
-
142
-
-
0026735595
-
Antikeratin antibodies: Diagnostic and prognostic markers for early rheumatoid arthritis
-
Paimela, L. et al. (1992) Antikeratin antibodies: diagnostic and prognostic markers for early rheumatoid arthritis. Ann. Rheum. Dis. 51, 743-746
-
(1992)
Ann. Rheum. Dis.
, vol.51
, pp. 743-746
-
-
Paimela, L.1
-
143
-
-
0027217907
-
The cytokeratin filament-aggregating protein filaggrin is the target of the so-called antikeratin antibodies, autoantibodies specific for rheumatoid arthritis
-
Simon, M. et al. (1993) The cytokeratin filament-aggregating protein filaggrin is the target of the so-called antikeratin antibodies, autoantibodies specific for rheumatoid arthritis. J. Clin. Invest. 92, 1387-1393
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 1387-1393
-
-
Simon, M.1
-
144
-
-
0025775769
-
Antiperinuclear factor, a marker autoantibody for rheumatoid arthritis: Colocalisation of the perinuclear factor and profilaggrin
-
Hoet, R.M. et al. (1991) Antiperinuclear factor, a marker autoantibody for rheumatoid arthritis: colocalisation of the perinuclear factor and profilaggrin. Ann. Rheum. Dis. 50, 611-618
-
(1991)
Ann. Rheum. Dis.
, vol.50
, pp. 611-618
-
-
Hoet, R.M.1
-
145
-
-
0029017016
-
The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies
-
Sebbag, M. et al. (1995) The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies. J. Clin. Invest. 95, 2672-2679
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2672-2679
-
-
Sebbag, M.1
-
146
-
-
0031974911
-
Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
-
Schellekens, G.A. et al. (1998) Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J. Clin. Invest. 101, 273-281
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 273-281
-
-
Schellekens, G.A.1
-
147
-
-
0034066626
-
In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum
-
Masson-Bessiere, C. et al. (2000) In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum. Clin. Exp. Immunol. 119, 544-552
-
(2000)
Clin. Exp. Immunol.
, vol.119
, pp. 544-552
-
-
Masson-Bessiere, C.1
-
148
-
-
0035869593
-
The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin
-
Masson-Bessiere, C. et al. (2001) The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin. J. Immunol. 166, 4177-4184
-
(2001)
J. Immunol.
, vol.166
, pp. 4177-4184
-
-
Masson-Bessiere, C.1
-
149
-
-
34547575872
-
Prevalence and clinical significance of antibodies to citrullinated fibrinogen (ACF) in Chinese patients with rheumatoid arthritis
-
Zhao, Y. et al. (2007) Prevalence and clinical significance of antibodies to citrullinated fibrinogen (ACF) in Chinese patients with rheumatoid arthritis. Clin. Rheumatol. 26, 1505-1512
-
(2007)
Clin. Rheumatol.
, vol.26
, pp. 1505-1512
-
-
Zhao, Y.1
-
150
-
-
33746572741
-
Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids
-
Takizawa, Y. et al. (2006) Citrullinated fibrinogen detected as a soluble citrullinated autoantigen in rheumatoid arthritis synovial fluids. Ann. Rheum. Dis. 65, 1013-1020
-
(2006)
Ann. Rheum. Dis.
, vol.65
, pp. 1013-1020
-
-
Takizawa, Y.1
-
151
-
-
70350435268
-
Effect of citrullination on the function and conformation of antithrombin
-
Ordonez, A. et al. (2009) Effect of citrullination on the function and conformation of antithrombin. FEBS J. 276, 6763-6772
-
(2009)
FEBS J
, vol.276
, pp. 6763-6772
-
-
Ordonez, A.1
-
152
-
-
78649719869
-
Increased levels of citrullinated antithrombin in plasma of patients with rheumatoid arthritis and colorectal adenocarcinoma determined by a newly developed ELISA using a specific monoclonal antibody
-
Ordonez, A. et al. (2010) Increased levels of citrullinated antithrombin in plasma of patients with rheumatoid arthritis and colorectal adenocarcinoma determined by a newly developed ELISA using a specific monoclonal antibody. Thromb. Haemost. 104, 1143-1149
-
(2010)
Thromb. Haemost.
, vol.104
, pp. 1143-1149
-
-
Ordonez, A.1
-
153
-
-
27744516866
-
Citrullination of fibronectin in rheumatoid arthritis synovial tissue
-
Chang, X. et al. (2005) Citrullination of fibronectin in rheumatoid arthritis synovial tissue. Rheumatology (Oxford) 44, 1374-1382
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 1374-1382
-
-
Chang, X.1
-
154
-
-
20544456092
-
Anti-citrullinated collagen type i antibody is a target of autoimmunity in rheumatoid arthritis
-
Suzuki, A. et al. (2005) Anti-citrullinated collagen type I antibody is a target of autoimmunity in rheumatoid arthritis. Biochem. Biophys. Res. Commun. 333, 418-426
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.333
, pp. 418-426
-
-
Suzuki, A.1
-
155
-
-
18844386764
-
Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis
-
Burkhardt, H. et al. (2005) Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis. Eur. J. Immunol. 35, 1643-1652
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1643-1652
-
-
Burkhardt, H.1
-
156
-
-
33644667809
-
Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis
-
Kinloch, A. et al. (2005) Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis. Arthritis Res. Ther. 7, R1421-R1429
-
(2005)
Arthritis Res. Ther.
, vol.7
-
-
Kinloch, A.1
-
157
-
-
30944445960
-
Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis
-
Okazaki, Y. et al. (2006) Identification of citrullinated eukaryotic translation initiation factor 4G1 as novel autoantigen in rheumatoid arthritis. Biochem. Biophys. Res. Commun. 341, 94-100
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.341
, pp. 94-100
-
-
Okazaki, Y.1
-
158
-
-
1842619397
-
Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin
-
Vossenaar, E.R. et al. (2004) Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin. Arthritis Res. Ther. 6, R142-R150
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Vossenaar, E.R.1
-
159
-
-
0034467068
-
Insights into rheumatoid arthritis derived from the Sa immune system
-
Menard, H.A. et al. (2000) Insights into rheumatoid arthritis derived from the Sa immune system. Arthritis Res. 2, 429-432
-
(2000)
Arthritis Res
, vol.2
, pp. 429-432
-
-
Menard, H.A.1
-
160
-
-
34547785469
-
Mutation and citrullination modifies vimentin to a novel autoantigen for rheumatoid arthritis
-
Bang, H. et al. (2007) Mutation and citrullination modifies vimentin to a novel autoantigen for rheumatoid arthritis. Arthritis Rheum. 56, 2503-2511
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 2503-2511
-
-
Bang, H.1
-
161
-
-
70350516712
-
Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach
-
Matsuo, K. et al. (2006) Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach. Arthritis Res. Ther. 8, R175
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Matsuo, K.1
-
162
-
-
64549131255
-
Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzymes
-
Goeb, V. et al. (2009) Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzymes. Arthritis Res. Ther. 11, R38
-
(2009)
Arthritis Res. Ther.
, vol.11
-
-
Goeb, V.1
-
163
-
-
47749141839
-
Detection of citrullinated proteins in synovial fluids derived from patients with rheumatoid arthritis by proteomicsbased analysis
-
Tabushi, Y. et al. (2008) Detection of citrullinated proteins in synovial fluids derived from patients with rheumatoid arthritis by proteomicsbased analysis. Ann. Clin. Biochem. 45, 413-417
-
(2008)
Ann. Clin. Biochem.
, vol.45
, pp. 413-417
-
-
Tabushi, Y.1
-
164
-
-
33745725970
-
Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: A systematic literature review
-
Avouac, J. et al. (2006) Diagnostic and predictive value of anti-cyclic citrullinated protein antibodies in rheumatoid arthritis: a systematic literature review. Ann. Rheum. Dis. 65, 845-851
-
(2006)
Ann. Rheum. Dis.
, vol.65
, pp. 845-851
-
-
Avouac, J.1
-
165
-
-
74849107568
-
Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients
-
Snir, O. et al. (2010) Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis Rheum. 62, 44-52
-
(2010)
Arthritis Rheum
, vol.62
, pp. 44-52
-
-
Snir, O.1
-
166
-
-
33645088938
-
Antibodies against transglutaminases, peptidylarginine deiminase and citrulline in rheumatoid arthritis - New pathways to epitope spreading
-
Roth, E.B. et al. (2006) Antibodies against transglutaminases, peptidylarginine deiminase and citrulline in rheumatoid arthritis - new pathways to epitope spreading. Clin. Exp. Rheumatol. 24, 12-18
-
(2006)
Clin. Exp. Rheumatol.
, vol.24
, pp. 12-18
-
-
Roth, E.B.1
-
167
-
-
22144476560
-
Peptidylarginine deiminase 4 (PADI4) identified as a conformation- dependent autoantigen in rheumatoid arthritis
-
Takizawa, Y. et al. (2005) Peptidylarginine deiminase 4 (PADI4) identified as a conformation-dependent autoantigen in rheumatoid arthritis. Scand. J. Rheumatol. 34, 212-215
-
(2005)
Scand. J. Rheumatol.
, vol.34
, pp. 212-215
-
-
Takizawa, Y.1
-
168
-
-
0842287339
-
Peptidylarginine deiminase, the arginine to citrulline converting enzyme, is frequently recognized by sera of patientswith rheumatoid arthritis, systemic lupus erythematosus and primary Sjogren syndrome
-
Nissinen, R. et al. (2003) Peptidylarginine deiminase, the arginine to citrulline converting enzyme, is frequently recognized by sera of patientswith rheumatoid arthritis, systemic lupus erythematosus and primary Sjogren syndrome. Scand. J. Rheumatol. 32, 337-342
-
(2003)
Scand. J. Rheumatol.
, vol.32
, pp. 337-342
-
-
Nissinen, R.1
-
169
-
-
77956365219
-
Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis
-
Kolfenbach, J.R. et al. (2010) Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis. Arthritis Rheum. 62, 2633-2639
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2633-2639
-
-
Kolfenbach, J.R.1
-
170
-
-
44949231413
-
Prevalence and significance of anti-peptidylarginine deiminase 4 antibodies in rheumatoid arthritis
-
Zhao, J. et al. (2008) Prevalence and significance of anti-peptidylarginine deiminase 4 antibodies in rheumatoid arthritis. J. Rheumatol. 35, 969-974
-
(2008)
J. Rheumatol.
, vol.35
, pp. 969-974
-
-
Zhao, J.1
-
171
-
-
39549108676
-
Serum IgG antibodies to peptidylarginine deiminase 4 in rheumatoid arthritis and associations with disease severity
-
Halvorsen, E.H. et al. (2008) Serum IgG antibodies to peptidylarginine deiminase 4 in rheumatoid arthritis and associations with disease severity. Ann. Rheum. Dis. 67, 414-417
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 414-417
-
-
Halvorsen, E.H.1
-
172
-
-
74849129601
-
Rheumatoid arthritis-specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen
-
Auger, I. et al. (2010) Rheumatoid arthritis-specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen. Arthritis Rheum. 62, 126-131
-
(2010)
Arthritis Rheum
, vol.62
, pp. 126-131
-
-
Auger, I.1
-
173
-
-
84863634836
-
Anti-PAD4 autoantibodies in rheumatoid arthritis: Levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
-
Pollmann, S. et al. (2012) Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate. Rheumatol. Int. 32, 1271-1276
-
(2012)
Rheumatol. Int.
, vol.32
, pp. 1271-1276
-
-
Pollmann, S.1
-
174
-
-
1842453329
-
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages
-
Vossenaar, E.R. et al. (2004) Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages. Ann. Rheum. Dis. 63, 373-381
-
(2004)
Ann. Rheum. Dis.
, vol.63
, pp. 373-381
-
-
Vossenaar, E.R.1
-
175
-
-
23644436874
-
Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity
-
De Rycke, L. et al. (2005) Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase as pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity. Arthritis Rheum. 52, 2323-2330
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2323-2330
-
-
De Rycke, L.1
-
176
-
-
49449111807
-
Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis
-
Kinloch, A. et al. (2008) Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis. Arthritis Rheum. 58, 2287-2295
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2287-2295
-
-
Kinloch, A.1
-
177
-
-
79959461123
-
Autopathogenic correlation of periodontitis and rheumatoid arthritis
-
Routsias, J.G. et al. (2011) Autopathogenic correlation of periodontitis and rheumatoid arthritis. Rheumatology (Oxford) 50, 1189-1193
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. 1189-1193
-
-
Routsias, J.G.1
-
178
-
-
78650553596
-
Bacterial and human peptidylarginine deiminases: Targets for inhibiting the autoimmune response in rheumatoid arthritis?
-
Mangat, P. et al. (2010) Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis? Arthritis Res Ther. 12, 209
-
(2010)
Arthritis Res Ther.
, vol.12
, pp. 209
-
-
Mangat, P.1
-
179
-
-
0023500817
-
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
-
Gregersen, P.K. et al. (1987) The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum. 30, 1205-1213
-
(1987)
Arthritis Rheum
, vol.30
, pp. 1205-1213
-
-
Gregersen, P.K.1
-
180
-
-
43949124836
-
The HLA-DRB1 shared epitope in Caucasians with rheumatoid arthritis: A lesson learned from tic-tac-toe
-
Bridges, S.L., Jr et al. (2008) The HLA-DRB1 shared epitope in Caucasians with rheumatoid arthritis: a lesson learned from tic-tac-toe. Arthritis Rheum. 58, 1211-1215
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1211-1215
-
-
Bridges Jr., S.L.1
-
181
-
-
0038107566
-
Cutting edge: The conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1&z.ast;0401 MHC class II molecule
-
Hill, J.A. et al. (2003) Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1&z.ast;0401 MHC class II molecule. J. Immunol. 171, 538-541
-
(2003)
J. Immunol.
, vol.171
, pp. 538-541
-
-
Hill, J.A.1
-
182
-
-
39749129030
-
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture
-
Hughes, L.B. et al. (2008) The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum. 58, 349-358
-
(2008)
Arthritis Rheum
, vol.58
, pp. 349-358
-
-
Hughes, L.B.1
-
183
-
-
7844245773
-
Identification of the gene loci that predispose to rheumatoid arthritis
-
Shiozawa, S. et al. (1998) Identification of the gene loci that predispose to rheumatoid arthritis. Int. Immunol. 10, 1891-1895
-
(1998)
Int. Immunol.
, vol.10
, pp. 1891-1895
-
-
Shiozawa, S.1
-
184
-
-
0042667153
-
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
-
Suzuki, A. et al. (2003) Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat. Genet. 34, 395-402
-
(2003)
Nat. Genet.
, vol.34
, pp. 395-402
-
-
Suzuki, A.1
-
185
-
-
31044440425
-
A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans
-
Kang, C.P. et al. (2006) A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans. Arthritis Rheum. 54, 90-96
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 90-96
-
-
Kang, C.P.1
-
186
-
-
67449108524
-
A functional haplotype of PADI4 gene in rheumatoid arthritis: Positive correlation in a French population
-
Gandjbakhch, F. et al. (2009) A functional haplotype of PADI4 gene in rheumatoid arthritis: positive correlation in a French population. J. Rheumatol. 36, 881-886
-
(2009)
J. Rheumatol.
, vol.36
, pp. 881-886
-
-
Gandjbakhch, F.1
-
187
-
-
34247551166
-
Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: A case-control study
-
Hoppe, B. et al. (2006) Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study. Arthritis Res. Ther. 8, R34
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Hoppe, B.1
-
188
-
-
22844452701
-
Genetic and genomic studies of PADI4 in rheumatoid arthritis
-
Harney, S.M. et al. (2005) Genetic and genomic studies of PADI4 in rheumatoid arthritis. Rheumatology (Oxford) 44, 869-872
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 869-872
-
-
Harney, S.M.1
-
189
-
-
35748975672
-
Genetic background of anticyclic citrullinated peptide autoantibody production in Hungarian patients with rheumatoid arthritis
-
Poor, G. et al. (2007) Genetic background of anticyclic citrullinated peptide autoantibody production in Hungarian patients with rheumatoid arthritis. Ann. N. Y. Acad. Sci. 1110, 23-32
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1110
, pp. 23-32
-
-
Poor, G.1
-
190
-
-
27144488150
-
PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population
-
Martinez, A. et al. (2005) PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population. Rheumatology (Oxford) 44, 1263-1266
-
(2005)
Rheumatology (Oxford)
, vol.44
, pp. 1263-1266
-
-
Martinez, A.1
-
191
-
-
20144388805
-
A family based study shows no association between rheumatoid arthritis
-
Caponi, L. et al. (2005) A family based study shows no association between rheumatoid arthritis and the PADI4 gene in a white French population. Ann. Rheum. Dis. 64, 587-593
-
(2005)
Ann. Rheum. Dis.
, vol.64
, pp. 587-593
-
-
Caponi, L.1
-
192
-
-
23944434706
-
Functional haplotypes of PADI4: Relevance for rheumatoid arthritis specific synovial intracellular citrullinated proteins and anticitrullinated protein antibodies
-
Cantaert, T. et al. (2005) Functional haplotypes of PADI4: relevance for rheumatoid arthritis specific synovial intracellular citrullinated proteins and anticitrullinated protein antibodies. Ann. Rheum. Dis. 64, 1316-1320
-
(2005)
Ann. Rheum. Dis.
, vol.64
, pp. 1316-1320
-
-
Cantaert, T.1
-
193
-
-
33750366621
-
Evaluation of allele frequencies in the PADI4 gene and anti-cyclic citrullinated peptide antibodies of patients with rheumatoid arthritis in a Japanese population
-
Suzuki, M. et al. (2006) Evaluation of allele frequencies in the PADI4 gene and anti-cyclic citrullinated peptide antibodies of patients with rheumatoid arthritis in a Japanese population. Ann. Rheum. Dis. 65, 1399-1400
-
(2006)
Ann. Rheum. Dis.
, vol.65
, pp. 1399-1400
-
-
Suzuki, M.1
-
194
-
-
28144441356
-
Replication of putative candidate-gene associations with rheumatoid arthritis in >4000 samples from North America and Sweden: Association of susceptibility with PTPN22, CTLA4, and PADI4
-
Plenge, R.M. et al. (2005) Replication of putative candidate-gene associations with rheumatoid arthritis in >4000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am. J. Hum. Genet. 77, 1044-1060
-
(2005)
Am. J. Hum. Genet.
, vol.77
, pp. 1044-1060
-
-
Plenge, R.M.1
-
195
-
-
26844480664
-
Association between PADI4 and rheumatoid arthritis: A replication study
-
Ikari, K. et al. (2005) Association between PADI4 and rheumatoid arthritis: a replication study. Arthritis Rheum. 52, 3054-3057
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3054-3057
-
-
Ikari, K.1
-
196
-
-
33745591928
-
Association between PADI4 and rheumatoid arthritis: A meta-analysis
-
Iwamoto, T. et al. (2006) Association between PADI4 and rheumatoid arthritis: a meta-analysis. Rheumatology (Oxford) 45, 804-807
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 804-807
-
-
Iwamoto, T.1
-
197
-
-
34250183488
-
PADI4 polymorphisms and rheumatoid arthritis susceptibility: A meta-analysis
-
Lee, Y.H. et al. (2007) PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis. Rheumatol. Int. 27, 827-833
-
(2007)
Rheumatol. Int.
, vol.27
, pp. 827-833
-
-
Lee, Y.H.1
-
198
-
-
67449168647
-
Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis
-
Hoppe, B. et al. (2009) Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis. Ann. Rheum. Dis. 68, 898-903
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 898-903
-
-
Hoppe, B.1
-
199
-
-
34248577163
-
Association of anti-cyclic citrullinated peptide antibody levels with PADI4 haplotypes in early rheumatoid arthritis and with shared epitope alleles in very late rheumatoid arthritis
-
Cha, S. et al. (2007) Association of anti-cyclic citrullinated peptide antibody levels with PADI4 haplotypes in early rheumatoid arthritis and with shared epitope alleles in very late rheumatoid arthritis. Arthritis Rheum. 56, 1454-1463
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1454-1463
-
-
Cha, S.1
-
200
-
-
39549095425
-
Lack of association between PADI4 and functional severity in Japanese rheumatoid arthritis patients
-
Nishimoto, K. et al. (2008) Lack of association between PADI4 and functional severity in Japanese rheumatoid arthritis patients. Ann. Rheum. Dis. 67, 431-432
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 431-432
-
-
Nishimoto, K.1
-
201
-
-
47249163722
-
Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis
-
Harris, M.L. et al. (2008) Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis. Arthritis Rheum. 58, 1958-1967
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1958-1967
-
-
Harris, M.L.1
-
202
-
-
34548427925
-
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus
-
Remmers, E.F. et al. (2007) STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. N. Engl. J. Med. 357, 977-986
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 977-986
-
-
Remmers, E.F.1
-
203
-
-
79953865892
-
Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population
-
Zhu, J. et al. (2011) Single nucleotide polymorphisms at the TRAF1/C5 locus are associated with rheumatoid arthritis in a Han Chinese population. BMC Med. Genet. 12, 53
-
(2011)
BMC Med. Genet.
, vol.12
, pp. 53
-
-
Zhu, J.1
-
204
-
-
33846231479
-
Polymorphisms in the IL4 and IL4RA genes in Colombian patients with rheumatoid arthritis
-
Moreno, O. et al. (2007) Polymorphisms in the IL4 and IL4RA genes in Colombian patients with rheumatoid arthritis. J. Rheumatol. 34, 36-42
-
(2007)
J. Rheumatol.
, vol.34
, pp. 36-42
-
-
Moreno, O.1
-
205
-
-
66449118743
-
Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: All alleles are important
-
Lundstrom, E. et al. (2009) Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important. Arthritis Rheum. 60, 1597-1603
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1597-1603
-
-
Lundstrom, E.1
-
206
-
-
53149103590
-
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
-
Makrygiannakis, D. et al. (2008) Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Ann. Rheum. Dis. 67, 1488-1492
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1488-1492
-
-
Makrygiannakis, D.1
-
207
-
-
79951515173
-
PADI4 polymorphism predisposes male smokers to rheumatoid arthritis
-
Kochi, Y. et al. (2011) PADI4 polymorphism predisposes male smokers to rheumatoid arthritis. Ann. Rheum. Dis. 70, 512-515
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 512-515
-
-
Kochi, Y.1
-
208
-
-
12944329841
-
Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin
-
Nachat, R. et al. (2005) Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin. J. Invest. Dermatol. 124, 384-393
-
(2005)
J. Invest. Dermatol.
, vol.124
, pp. 384-393
-
-
Nachat, R.1
-
209
-
-
0025353886
-
Immunohistochemical demonstration of peptidylarginine deiminase in human sweat glands
-
Urano, Y. et al. (1990) Immunohistochemical demonstration of peptidylarginine deiminase in human sweat glands. Am. J. Dermatopathol. 12, 249-255
-
(1990)
Am. J. Dermatopathol.
, vol.12
, pp. 249-255
-
-
Urano, Y.1
-
210
-
-
69049101987
-
The expression of PADI4 in synovium of rheumatoid arthritis
-
Chang, X. et al. (2009) The expression of PADI4 in synovium of rheumatoid arthritis. Rheumatol. Int. 29, 1411-1416
-
(2009)
Rheumatol. Int.
, vol.29
, pp. 1411-1416
-
-
Chang, X.1
-
211
-
-
0021000787
-
Purification and characterization of peptidylarginine deiminase from rabbit skeletal muscle
-
Takahara, H. et al. (1983) Purification and characterization of peptidylarginine deiminase from rabbit skeletal muscle. J. Biochem. 94, 1945-1953
-
(1983)
J. Biochem.
, vol.94
, pp. 1945-1953
-
-
Takahara, H.1
-
212
-
-
0030856551
-
Heparin-dependent modification of the reactive center arginine of antithrombin and consequent increase in heparin binding affinity
-
Pike, R.N. et al. (1997) Heparin-dependent modification of the reactive center arginine of antithrombin and consequent increase in heparin binding affinity. J. Biol. Chem. 272, 19652-19655
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19652-19655
-
-
Pike, R.N.1
-
213
-
-
0028914527
-
Studies of calcineurin-calmodulin interaction: Probing the role of arginine residues using peptidylarginine deiminase
-
Imparl, J.M. et al. (1995) Studies of calcineurin-calmodulin interaction: probing the role of arginine residues using peptidylarginine deiminase. Arch. Biochem. Biophys. 318, 370-377
-
(1995)
Arch. Biochem. Biophys.
, vol.318
, pp. 370-377
-
-
Imparl, J.M.1
-
214
-
-
0026246641
-
Enzymic modification of alpha s1-casein with peptidylarginine deiminase: Preparation of less acid-coagulable and less calcium-sensitive casein
-
Azuma, N. et al. (1991) Enzymic modification of alpha s1-casein with peptidylarginine deiminase: preparation of less acid-coagulable and less calcium-sensitive casein. J. Dairy Res. 58, 421-429
-
(1991)
J. Dairy Res.
, vol.58
, pp. 421-429
-
-
Azuma, N.1
-
215
-
-
33845618038
-
Association of citrullinated proteins with synovial exosomes
-
Skriner, K. et al. (2006) Association of citrullinated proteins with synovial exosomes. Arthritis Rheum. 54, 3809-3814
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3809-3814
-
-
Skriner, K.1
-
216
-
-
78651426965
-
Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins
-
Van Steendam, K. et al. (2010) Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins. Arthritis Res. Ther. 12, R132
-
(2010)
Arthritis Res. Ther.
, vol.12
-
-
Van Steendam, K.1
-
217
-
-
0028903763
-
Enzymatic deimination of glycogen phosphorylase and a peptide of the phosphorylation site: Identification of modification and roles in phosphorylation and activity
-
Luo, S. et al. (1995) Enzymatic deimination of glycogen phosphorylase and a peptide of the phosphorylation site: identification of modification and roles in phosphorylation and activity. Arch. Biochem. Biophys. 318, 362-369
-
(1995)
Arch. Biochem. Biophys.
, vol.318
, pp. 362-369
-
-
Luo, S.1
|