Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease

Journal of Neuroscience Research

Volumn 80, Issue 1, 2005, Pages 120-128

  Ishigami, Akihito ^a   Ohsawa, Takako ^a   Hiratsuka, Masaharu ^b   Taguchi, Hirom ^a   Kobayashi, Saori ^a   Saito, Yuko ^a   Murayama, Shigeo ^a   Asaga, Hiroaki ^c   Toda, Tosifusa ^a   Kimura, Narimichi ^a   Maruyama, Naoki ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c MEIJI UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; Astrocyte; Citrulline; Glial fibrillary acidic protein; PAD; Vimentin

Indexed keywords

ANTIBODY; BRAIN EXTRACT; BRAIN PROTEIN; CALCIUM ION; CITRULLINATED PROTEIN; CITRULLINE; GLIAL FIBRILLARY ACIDIC PROTEIN; PEPTIDYLARGININE DEIMINASE 2; PROTEIN ARGININE DEIMINASE; UNCLASSIFIED DRUG; VIMENTIN;

AGED; ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; CATALYSIS; CATALYST; CONTROLLED STUDY; DENTATE GYRUS; DISEASE MARKER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; HIPPOCAMPUS; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NERVE CELL DEGENERATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CITRULLINE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; HYDROLASES; IMMUNOHISTOCHEMISTRY; MALE; PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VIMENTIN;

EID: 20244368810     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20431     Document Type: Article

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