-
1
-
-
84856405512
-
The mystery of missing heritability: Genetic interactions create phantom heritability
-
Zuk O, Hechter E, Sunyaev SR et al. (2012) The mystery of missing heritability: genetic interactions create phantom heritability. Proc Natl Acad Sci USA 109, 1193-1198.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
-
2
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ et al. (2009) Finding the missing heritability of complex diseases. Nature 461, 747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
3
-
-
33645760679
-
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings
-
Visscher PM, Medland SE, Ferreira MA et al. (2006) Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet 2, e41.
-
(2006)
PLoS Genet
, vol.2
-
-
Visscher, P.M.1
Medland, S.E.2
Ferreira, M.A.3
-
4
-
-
84860264016
-
Common variants in the CD36 gene are associated with oral fat perception, fat preferences, and obesity in African Americans
-
Keller KL, Liang LC, Sakimura J et al. (2012) Common variants in the CD36 gene are associated with oral fat perception, fat preferences, and obesity in African Americans. Obesity (Silver Spring) 20, 1066-1073.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 1066-1073
-
-
Keller, K.L.1
Liang, L.C.2
Sakimura, J.3
-
5
-
-
83155168396
-
Polymorphisms in the neuropeptide y gene and the risk of obesity: Findings from two prospective cohorts
-
Yeung EH, Zhang C, Chen J et al. (2011) Polymorphisms in the neuropeptide Y gene and the risk of obesity: findings from two prospective cohorts. J Clin Endocrinol Metab 96, E2055-E2062.
-
(2011)
J Clin Endocrinol Metab
, vol.96
-
-
Yeung, E.H.1
Zhang, C.2
Chen, J.3
-
6
-
-
68149141358
-
Nutrigenetics and personalised nutrition: How far have we progressed and are we likely to get there?
-
Rimbach G & Minihane AM (2009) Nutrigenetics and personalised nutrition: how far have we progressed and are we likely to get there? Proc Nutr Soc 68, 162-172.
-
(2009)
Proc Nutr Soc
, vol.68
, pp. 162-172
-
-
Rimbach, G.1
Minihane, A.M.2
-
8
-
-
84867398818
-
The role of nutrition on epigenetic modifications and their implications on health
-
Jimenez-Chillaron JC, Diaz R, Martinez D et al. (2012) The role of nutrition on epigenetic modifications and their implications on health. Biochimie 94, 2242-2263.
-
(2012)
Biochimie
, vol.94
, pp. 2242-2263
-
-
Jimenez-Chillaron, J.C.1
Diaz, R.2
Martinez, D.3
-
9
-
-
49749105254
-
Effect of sex and genotype on cardiovascular biomarker response to fish oils: The FINGEN study
-
Caslake MJ, Miles EA, Kofler BM et al. (2008) Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN study. Am J Clin Nutr 88, 618-629.
-
(2008)
Am J Clin Nutr
, vol.88
, pp. 618-629
-
-
Caslake, M.J.1
Miles, E.A.2
Kofler, B.M.3
-
10
-
-
79952474482
-
From GWAS to biology: Lessons from FTO
-
Tung YC & Yeo GS (2011) From GWAS to biology: lessons from FTO. Ann NY Acad Sci 1220, 162-171.
-
(2011)
Ann NY Acad Sci
, vol.1220
, pp. 162-171
-
-
Tung, Y.C.1
Yeo, G.S.2
-
11
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
DOI 10.1126/science.1141634
-
Frayling TM, Timpson NJ, Weedon MN et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316, 889-894. (Pubitemid 46764279)
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.-R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.F.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.A.36
Doney, A.S.F.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
12
-
-
77956331627
-
Integrating common and rare genetic variation in diverse human populations
-
Altshuler DM, Gibbs RA, Peltonen L et al. (2010) Integrating common and rare genetic variation in diverse human populations. Nature 467, 52-58.
-
(2010)
Nature
, vol.467
, pp. 52-58
-
-
Altshuler, D.M.1
Gibbs, R.A.2
Peltonen, L.3
-
13
-
-
79957506175
-
Strategic approaches to unraveling genetic causes of cardiovascular diseases
-
Marian AJ & Belmont J (2011) Strategic approaches to unraveling genetic causes of cardiovascular diseases. Circ Res 108, 1252-1269.
-
(2011)
Circ Res
, vol.108
, pp. 1252-1269
-
-
Marian, A.J.1
Belmont, J.2
-
14
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
DOI 10.1126/science.1109557
-
Klein RJ, Zeiss C, Chew EY et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308, 385-389. (Pubitemid 40530070)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
16
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich TM, Musunuru K, Smith AV et al. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
-
17
-
-
79951481957
-
Initial impact of the sequencing of the human genome
-
Lander ES (2011) Initial impact of the sequencing of the human genome. Nature 470, 187-197.
-
(2011)
Nature
, vol.470
, pp. 187-197
-
-
Lander, E.S.1
-
18
-
-
84859575363
-
Genetic determinants of common obesity and their value in prediction
-
Loos RJ (2012) Genetic determinants of common obesity and their value in prediction. Best Pract Res Clin Endocrinol Metab 26, 211-226.
-
(2012)
Best Pract Res Clin Endocrinol Metab
, vol.26
, pp. 211-226
-
-
Loos, R.J.1
-
19
-
-
78049337953
-
Association analyses of 249, 796 individuals reveal 18 new loci associated with body mass index
-
Speliotes EK, Willer CJ, Berndt SI et al. (2010) Association analyses of 249, 796 individuals reveal 18 new loci associated with body mass index. Nat Genet 42, 937-948.
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
-
20
-
-
84855925920
-
Rare and common variants: Twenty arguments
-
Gibson G (2011) Rare and common variants: twenty arguments. Nat Rev Genet 13, 135-145.
-
(2011)
Nat Rev Genet
, vol.13
, pp. 135-145
-
-
Gibson, G.1
-
21
-
-
79954594698
-
Correcting away the hidden heritability
-
Williams SM & Haines JL (2011) Correcting away the hidden heritability. Ann Hum Genet 75, 348-350.
-
(2011)
Ann Hum Genet
, vol.75
, pp. 348-350
-
-
Williams, S.M.1
Haines, J.L.2
-
22
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
DOI 10.1038/nature05887, PII NATURE05887
-
Easton DF, Pooley KA, Dunning AM et al. (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447, 1087-1093. (Pubitemid 47014426)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.P.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
Wareham, N.11
Ahmed, S.12
Healey, C.S.13
Bowman, R.14
Meyer, K.B.15
Haiman, C.A.16
Kolonel, L.K.17
Henderson, B.E.18
Le Marchand, L.19
Brennan, P.20
Sangrajrang, S.21
Gaborieau, V.22
Odefrey, F.23
Shen, C.-Y.24
Wu, P.-E.25
Wang, H.-C.26
Eccles, D.27
Evans, D.G.28
Peto, J.29
Fletcher, O.30
Johnson, N.31
Seal, S.32
Stratton, M.R.33
more..
-
23
-
-
77950544633
-
Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci
-
Consortium IMSG
-
Consortium IMSG (2010) Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum Mol Genet 19, 953-962.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 953-962
-
-
-
24
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
DOI 10.1038/nrg2344, PII NRG2344
-
McCarthy MI, Abecasis GR, Cardon LR et al. (2008) Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 9, 356-369. (Pubitemid 351556063)
-
(2008)
Nature Reviews Genetics
, vol.9
, Issue.5
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.A.6
Hirschhorn, J.N.7
-
25
-
-
33751329250
-
Global variation in copy number in the human genome
-
DOI 10.1038/nature05329, PII NATURE05329
-
Redon R, Ishikawa S, Fitch KR et al. (2006) Global variation in copy number in the human genome. Nature 444, 444-454. (Pubitemid 44809057)
-
(2006)
Nature
, vol.444
, Issue.7118
, pp. 444-454
-
-
Redon, R.1
Ishikawa, S.2
Fitch, K.R.3
Feuk, L.4
Perry, G.H.5
Andrews, T.D.6
Fiegler, H.7
Shapero, M.H.8
Carson, A.R.9
Chen, W.10
Cho, E.K.11
Dallaire, S.12
Freeman, J.L.13
Gonzalez, J.R.14
Gratacos, M.15
Huang, J.16
Kalaitzopoulos, D.17
Komura, D.18
MacDonald, J.R.19
Marshall, C.R.20
Mei, R.21
Montgomery, L.22
Nishimura, K.23
Okamura, K.24
Shen, F.25
Somerville, M.J.26
Tchinda, J.27
Valsesia, A.28
Woodwark, C.29
Yang, F.30
Zhang, J.31
Zerjal, T.32
Zhang, J.33
Armengol, L.34
Conrad, D.F.35
Estivill, X.36
Tyler-Smith, C.37
Carter, N.P.38
Aburatani, H.39
Lee, C.40
Jones, K.W.41
Scherer, S.W.42
Hurles, M.E.43
more..
-
26
-
-
84856244406
-
Implications of gene copy-number variation in health and diseases
-
Almal SH & Padh H (2012) Implications of gene copy-number variation in health and diseases. J Hum Genet 57, 6-13.
-
(2012)
J Hum Genet
, vol.57
, pp. 6-13
-
-
Almal, S.H.1
Padh, H.2
-
27
-
-
77950121267
-
Gene copy number variation and common human disease
-
Fanciulli M, Petretto E & Aitman TJ (2010) Gene copy number variation and common human disease. Clin Genet 77, 201-213.
-
(2010)
Clin Genet
, vol.77
, pp. 201-213
-
-
Fanciulli, M.1
Petretto, E.2
Aitman, T.J.3
-
28
-
-
39749197456
-
Genotype, haplotype and copy-number variation in worldwide human populations
-
DOI 10.1038/nature06742, PII NATURE06742
-
Jakobsson M, Scholz SW, Scheet P et al. (2008) Genotype, haplotype and copy-number variation in worldwide human populations. Nature 451, 998-1003. (Pubitemid 351301742)
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 998-1003
-
-
Jakobsson, M.1
Scholz, S.W.2
Scheet, P.3
Gibbs, J.R.4
VanLiere, J.M.5
Fung, H.-C.6
Szpiech, Z.A.7
Degnan, J.H.8
Wang, K.9
Guerreiro, R.10
Bras, J.M.11
Schymick, J.C.12
Hernandez, D.G.13
Traynor, B.J.14
Simon-Sanchez, J.15
Matarin, M.16
Britton, A.17
Van De Leemput, J.18
Rafferty, I.19
Bucan, M.20
Cann, H.M.21
Hardy, J.A.22
Rosenberg, N.A.23
Singleton, A.B.24
more..
-
29
-
-
84862605504
-
Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease
-
Bras J, Guerreiro R & Hardy J (2012) Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease. Nat Rev Neurosci 13, 453-464.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 453-464
-
-
Bras, J.1
Guerreiro, R.2
Hardy, J.3
-
30
-
-
84860373866
-
The 1000 Genomes Project: Data management and community access
-
Clarke L, Zheng-Bradley X, Smith R et al. (2012) The 1000 Genomes Project: data management and community access. Nat Methods 9, 459-462.
-
(2012)
Nat Methods
, vol.9
, pp. 459-462
-
-
Clarke, L.1
Zheng-Bradley, X.2
Smith, R.3
-
31
-
-
84455180777
-
Gene by sex interaction for measures of obesity in the Framingham Heart study
-
Benjamin AM, Suchindran S, Pearce K et al. (2011) Gene by sex interaction for measures of obesity in the Framingham Heart study. J Obes 2011, 329038.
-
(2011)
J Obes
, vol.2011
, pp. 329038
-
-
Benjamin, A.M.1
Suchindran, S.2
Pearce, K.3
-
32
-
-
78049349396
-
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
-
Heid IM, Jackson AU, Randall JC et al. (2010) Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 42, 949-960.
-
(2010)
Nat Genet
, vol.42
, pp. 949-960
-
-
Heid, I.M.1
Jackson, A.U.2
Randall, J.C.3
-
33
-
-
84155163221
-
Postprandial lipemia and cardiovascular disease risk: Interrelationships between dietary, physiological and genetic determinants
-
Jackson KG, Poppitt SD & Minihane AM (2012) Postprandial lipemia and cardiovascular disease risk: interrelationships between dietary, physiological and genetic determinants. Atherosclerosis 220, 22-33.
-
(2012)
Atherosclerosis
, vol.220
, pp. 22-33
-
-
Jackson, K.G.1
Poppitt, S.D.2
Minihane, A.M.3
-
34
-
-
49849088496
-
Influence of apoA-V gene variants on postprandial triglyceride metabolism: Impact of gender
-
Olano-Martin E, Abraham EC, Gill-Garrison R et al. (2008) Influence of apoA-V gene variants on postprandial triglyceride metabolism: impact of gender. J Lipid Res 49, 945-953.
-
(2008)
J Lipid Res
, vol.49
, pp. 945-953
-
-
Olano-Martin, E.1
Abraham, E.C.2
Gill-Garrison, R.3
-
35
-
-
84867873264
-
The leptin receptor Gln223Arg polymorphism (rs1137101) mediates the postprandial lipaemic response, but only in males
-
Jackson KG, Delgado-Lista J, Gill R et al. (2012) The leptin receptor Gln223Arg polymorphism (rs1137101) mediates the postprandial lipaemic response, but only in males. Atherosclerosis 225, 135-141.
-
(2012)
Atherosclerosis
, vol.225
, pp. 135-141
-
-
Jackson, K.G.1
Delgado-Lista, J.2
Gill, R.3
-
36
-
-
85027909214
-
Genetic risk factors for BMI and obesity in an ethnically diverse population: Results from the population architecture using genomics and epidemiology (PAGE) study
-
Epublication ahead of print version
-
Fesinmeyer MD, North KE, Ritchie MD et al. (2012) Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study. Obesity (Silver Spring) Epublication ahead of print version.
-
(2012)
Obesity (Silver Spring)
-
-
Fesinmeyer, M.D.1
North, K.E.2
Ritchie, M.D.3
-
37
-
-
77949772292
-
Gene-environment-wide association studies: Emerging approaches
-
Thomas D (2010) Gene-environment-wide association studies: emerging approaches. Nat. Rev. Genet. 11, 259-272.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 259-272
-
-
Thomas, D.1
-
38
-
-
79960947310
-
Genetic loci associated with plasma phospholipid n-3 fatty acids: A meta-analysis of genome-wide association studies from the CHARGE Consortium
-
Lemaitre RN, Tanaka T, Tang W et al. (2011) Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. PLoS Genet 7, e1002193.
-
(2011)
PLoS Genet
, vol.7
-
-
Lemaitre, R.N.1
Tanaka, T.2
Tang, W.3
-
39
-
-
77955052903
-
Common genetic determinants of vitamin D insufficiency: A genome-wide association study
-
Wang TJ, Zhang F, Richards JB et al. (2010) Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet 376, 180-188.
-
(2010)
Lancet
, vol.376
, pp. 180-188
-
-
Wang, T.J.1
Zhang, F.2
Richards, J.B.3
-
40
-
-
84861536364
-
Obesity susceptibility loci and dietary intake in the Look AHEAD Trial
-
McCaffery JM, Papandonatos GD, Peter I et al. (2012) Obesity susceptibility loci and dietary intake in the Look AHEAD Trial. Am J Clin Nutr 95, 1477-1486.
-
(2012)
Am J Clin Nutr
, vol.95
, pp. 1477-1486
-
-
McCaffery, J.M.1
Papandonatos, G.D.2
Peter, I.3
-
41
-
-
78650861064
-
Evidences on Three Relevant Obesogenes: MC4R FTO and PPARgamma. Approaches for Personalized Nutrition
-
Razquin C, Marti A & Martinez JA (2011) Evidences on three relevant obesogenes: MC4R, FTO and PPARgamma. Approaches for personalized nutrition. Mol Nutr Food Res 55, 136-149.
-
(2011)
Mol Nutr Food Res
, vol.55
, pp. 136-149
-
-
Razquin, C.1
Marti, A.2
Martinez, J.A.3
-
42
-
-
79953055780
-
Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids
-
Walker CG, Loos RJ, Olson AD et al. (2011) Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids. Atherosclerosis 215, 421-427.
-
(2011)
Atherosclerosis
, vol.215
, pp. 421-427
-
-
Walker, C.G.1
Loos, R.J.2
Olson, A.D.3
-
43
-
-
34548736492
-
Association of apolipoprotein e genotypes with lipid levels and coronary risk
-
DOI 10.1001/jama.298.11.1300
-
Bennet AM, Di Angelantonio E, Ye Z et al. (2007) Association of apolipoprotein E genotypes with lipid levels and coronary risk. JAMA: J Am Med Assoc 298, 1300-1311. (Pubitemid 47443344)
-
(2007)
Journal of the American Medical Association
, vol.298
, Issue.11
, pp. 1300-1311
-
-
Bennet, A.M.1
Di Angelantonio, E.2
Ye, Z.3
Wensley, F.4
Dahlin, A.5
Ahlbom, A.6
Keavney, B.7
Collins, R.8
Wiman, B.9
De Faire, U.10
Danesh, J.11
-
44
-
-
3142706539
-
Meta-analysis: Apolipoprotein E genotypes and risk for coronary heart disease
-
Song Y, Stampfer MJ & Liu S (2004) Meta-analysis: apoli-poprotein E genotypes and risk for coronary heart disease. Ann Intern Med 141, 137-147. (Pubitemid 38937836)
-
(2004)
Annals of Internal Medicine
, vol.141
, Issue.2
, pp. 137-147
-
-
Song, Y.1
Stampfer, M.J.2
Liu, S.3
-
45
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
DOI 10.1038/ng1934, PII NG1934
-
Bertram L, McQueen MB, Mullin K et al. (2007) Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 39, 17-23. (Pubitemid 46026496)
-
(2007)
Nature Genetics
, vol.39
, Issue.1
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
-
46
-
-
0035859488
-
Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: A prospective study
-
DOI 10.1016/S0140-6736(01)05330-2
-
Humphries SE, Talmud PJ, Hawe E et al. (2001) Apolipo-protein E4 and coronary heart disease in middle-aged men who smoke: a prospective study. Lancet 358, 115-119. (Pubitemid 32709850)
-
(2001)
Lancet
, vol.358
, Issue.9276
, pp. 115-119
-
-
Humphries, S.E.1
Talmud, P.J.2
Hawe, E.3
Bolla, M.4
Day, I.N.M.5
Miller, G.J.6
-
47
-
-
27644498592
-
The significant increase in cardiovascular disease risk in APOE ε4 carriers is evident only in men who smoke: Potential relationship between reduced antioxidant status and ApoE4
-
DOI 10.1111/j.1529-8817.2005.00205.x
-
Talmud PJ, Stephens JW, Hawe E et al. (2005) The significant increase in cardiovascular disease risk in APOEep-silon4 carriers is evident only in men who smoke: potential relationship between reduced antioxidant status and ApoE4. Ann Hum Genet 69, 613-622. (Pubitemid 41556316)
-
(2005)
Annals of Human Genetics
, vol.69
, Issue.6
, pp. 613-622
-
-
Talmud, P.J.1
Stephens, J.W.2
Hawe, E.3
Demissie, S.4
Cupples, L.A.5
Hurel, S.J.6
Humphries, S.E.7
Ordovas, J.M.8
-
48
-
-
79958786623
-
Variations in apolipoprotein e frequency with age in a pooled analysis of a large group of older people
-
McKay GJ, Silvestri G, Chakravarthy U et al. (2011) Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol 173, 1357-1364.
-
(2011)
Am J Epidemiol
, vol.173
, pp. 1357-1364
-
-
McKay, G.J.1
Silvestri, G.2
Chakravarthy, U.3
-
49
-
-
84860125157
-
The search for longevity and healthy aging genes: Insights from epidemiological studies and samples of long-lived individuals
-
Murabito JM, Yuan R & Lunetta KL (2012) The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals. J Gerontol A Biol Sci Med Sci 67, 470-479.
-
(2012)
J Gerontol A Biol Sci Med Sci
, vol.67
, pp. 470-479
-
-
Murabito, J.M.1
Yuan, R.2
Lunetta, K.L.3
-
50
-
-
34147170817
-
ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation
-
Minihane AM, Jofre-Monseny L, Olano-Martin E et al. (2007) ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation. Proc Nutr Soc 66, 183-197.
-
(2007)
Proc Nutr Soc
, vol.66
, pp. 183-197
-
-
Minihane, A.M.1
Jofre-Monseny, L.2
Olano-Martin, E.3
-
51
-
-
83455230813
-
Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: A systematic review and meta-analysis
-
Ward A, Crean S, Mercaldi CJ et al. (2012) Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis. Neuroepidemiology 38, 1-17.
-
(2012)
Neuroepidemiology
, vol.38
, pp. 1-17
-
-
Ward, A.1
Crean, S.2
Mercaldi, C.J.3
-
52
-
-
42249087308
-
The complete genome of an individual by massively parallel DNA sequencing
-
DOI 10.1038/nature06884, PII NATURE06884
-
Wheeler DA, Srinivasan M, Egholm M et al. (2008) The complete genome of an individual by massively parallel DNA sequencing. Nature 452, 872-876. (Pubitemid 351550870)
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 872-876
-
-
Wheeler, D.A.1
Srinivasan, M.2
Egholm, M.3
Shen, Y.4
Chen, L.5
McGuire, A.6
He, W.7
Chen, Y.-J.8
Makhijani, V.9
Roth, G.T.10
Gomes, X.11
Tartaro, K.12
Niazi, F.13
Turcotte, C.L.14
Irzyk, G.P.15
Lupski, J.R.16
Chinault, C.17
Song, X.-Z.18
Liu, Y.19
Yuan, Y.20
Nazareth, L.21
Qin, X.22
Muzny, D.M.23
Margulies, M.24
Weinstock, G.M.25
Gibbs, R.A.26
Rothberg, J.M.27
more..
-
53
-
-
78650686441
-
Apolipo-protein E: From lipid transport to neurobiology
-
Hauser PS, Narayanaswami V & Ryan RO (2011) Apolipo-protein E: from lipid transport to neurobiology. Prog Lipid Res 50, 62-74.
-
(2011)
Prog Lipid Res
, vol.50
, pp. 62-74
-
-
Hauser, P.S.1
Narayanaswami, V.2
Ryan, R.O.3
-
54
-
-
0033840462
-
ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype
-
Minihane AM, Khan S, Leigh-Firbank EC et al. (2000) ApoE polymorphism and fish oil supplementation in subjects with an atherogenic lipoprotein phenotype. Arterioscler Thromb Vasc Biol 20, 1990-1997. (Pubitemid 30648814)
-
(2000)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.20
, Issue.8
, pp. 1990-1997
-
-
Minihane, A.M.1
Khan, S.2
Leigh-Firbank, E.C.3
Talmud, P.4
Wright, J.W.5
Murphy, M.C.6
Griffin, B.A.7
Williams, C.M.8
-
55
-
-
77049108658
-
Contribution of apolipoprotein e genotype and docosahexaenoic acid to the LDL-cholesterol response to fish oil
-
Olano-Martin E, Anil E, Caslake MJ et al. (2010) Contribution of apolipoprotein E genotype and docosahexaenoic acid to the LDL-cholesterol response to fish oil. Atherosclerosis 209, 104-110.
-
(2010)
Atherosclerosis
, vol.209
, pp. 104-110
-
-
Olano-Martin, E.1
Anil, E.2
Caslake, M.J.3
-
56
-
-
84869816792
-
APOE genotype influences the triglyceride and C-reactive protein response to altered dietary fat intake in UK adults
-
the Press
-
Carvalho-Wells AL, Jackson KG, Lockyer S et al. (2012) APOE genotype influences the triglyceride and C-reactive protein response to altered dietary fat intake in UK adults. Am J Clin Nutr (In the Press).
-
(2012)
Am J Clin Nutr
-
-
Carvalho-Wells, A.L.1
Jackson, K.G.2
Lockyer, S.3
-
57
-
-
79959924129
-
Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: Interaction with apolipoprotein e genotype
-
Barberger-Gateau P, Samieri C, Feart C et al. (2011) Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: interaction with apolipoprotein E genotype. Curr Alzheimer Res 8, 479-491.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 479-491
-
-
Barberger-Gateau, P.1
Samieri, C.2
Feart, C.3
-
58
-
-
0041326346
-
Geographical and ethnic variation of the 677C>T allele of 5, 10 methylenetetrahydrofolate reductase (MTHFR): Findings from over 7000 newborns from 16 areas world wide
-
Wilcken B, Bamforth F, Li Z et al. (2003) Geographical and ethnic variation of the 677C>T allele of 5, 10 methylene-tetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide. J Med Genet 40, 619-625. (Pubitemid 37046918)
-
(2003)
Journal of Medical Genetics
, vol.40
, Issue.8
, pp. 619-625
-
-
Wilcken, B.1
Bamforth, F.2
Li, Z.3
Zhu, H.4
Ritvanen, A.5
Redlund, M.6
Stoll, C.7
Alembik, Y.8
Dott, B.9
Czeizel, A.E.10
Gelman-Kohan, Z.11
Scarano, G.12
Bianca, S.13
Ettore, G.14
Tenconi, R.15
Bellato, S.16
Scala, I.17
Mutchinick, O.M.18
Lopez, M.A.19
De Walle, H.20
Hofstra, R.21
Joutchenko, L.22
Kavteladze, L.23
Bermejo, E.24
Martinez-Frias, M.L.25
Gallagher, M.26
Erickson, J.D.27
Vollset, S.E.28
Mastroiacovo, P.29
Andria, G.30
Botto, L.D.31
more..
-
59
-
-
0029049553
-
A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
-
Frosst P, Blom HJ, Milos R et al. (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10, 111-113.
-
(1995)
Nat Genet
, vol.10
, pp. 111-113
-
-
Frosst, P.1
Blom, H.J.2
Milos, R.3
-
60
-
-
80051695692
-
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: A meta-analysis of genetic studies and randomised trials
-
Holmes MV, Newcombe P, Hubacek JA et al. (2011) Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Lancet 378, 584-594.
-
(2011)
Lancet
, vol.378
, pp. 584-594
-
-
Holmes, M.V.1
Newcombe, P.2
Hubacek, J.A.3
-
61
-
-
84856900237
-
Association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T and risk of myocardial infarction: A meta-analysis for 8, 140 cases and 10, 522 controls
-
Xuan C, Bai XY, Gao G et al. (2011) Association between polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T and risk of myocardial infarction: a meta-analysis for 8, 140 cases and 10, 522 controls. Arch Med Res 42, 677-685.
-
(2011)
Arch Med Res
, vol.42
, pp. 677-685
-
-
Xuan, C.1
Bai, X.Y.2
Gao, G.3
-
62
-
-
42149121986
-
Homocysteine, B-vitamins and CVD
-
DOI 10.1017/S0029665108007076, PII S0029665108007076
-
McNulty H, Pentieva K, Hoey L et al. (2008) Homocysteine, B-vitamins and CVD. Proc Nutr Soc 67, 232-237. (Pubitemid 351543405)
-
(2008)
Proceedings of the Nutrition Society
, vol.67
, Issue.2
, pp. 232-237
-
-
McNulty, H.1
Pentieva, K.2
Hoey, L.3
Ward, M.4
-
63
-
-
77149145514
-
Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C->T polymorphism in MTHFR
-
Horigan G, McNulty H, Ward M et al. (2010) Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C->T polymorphism in MTHFR. J Hypertens 28, 478-486.
-
(2010)
J Hypertens
, vol.28
, pp. 478-486
-
-
Horigan, G.1
McNulty, H.2
Ward, M.3
-
64
-
-
84857863459
-
Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: A 4-y follow-up
-
Wilson CP, Ward M, McNulty H et al. (2012) Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up. Am J Clin Nutr 95, 766-772.
-
(2012)
Am J Clin Nutr
, vol.95
, pp. 766-772
-
-
Wilson, C.P.1
Ward, M.2
McNulty, H.3
-
65
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
DOI 10.1038/35057062
-
Lander ES, Linton LM, Birren B et al. (2001) Initial sequencing and analysis of the human genome. Nature 409, 860-921. (Pubitemid 32165345)
-
(2001)
Nature
, vol.409
, Issue.6822
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
Levine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
Raymond, C.26
Rosetti, M.27
Santos, R.28
Sheridan, A.29
Sougnez, C.30
Stange-Thomann, N.31
Stojanovic, N.32
Subramanian, A.33
Wyman, D.34
Rogers, J.35
Sulston, J.36
Ainscough, R.37
Beck, S.38
Bentley, D.39
Burton, J.40
Clee, C.41
Carter, N.42
Coulson, A.43
Deadman, R.44
Deloukas, P.45
Dunham, A.46
Dunham, I.47
more..
-
66
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
International Human Genome Sequencing Consortium
-
International Human Genome Sequencing Consortium (2004) Finishing the euchromatic sequence of the human genome. Nature 431, 931-945.
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
|