Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease

Nature Reviews Neuroscience

Volumn 13, Issue 7, 2012, Pages 453-464

  Bras, Jose ^a   Guerreiro, Rita ^a   Hardy, John ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ALPHA SYNUCLEIN; APOLIPOPROTEIN E; CD2 ANTIGEN; CD33 ANTIGEN; CLUSTERIN; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C4B; EPHRIN RECEPTOR A1; HISTONE DEACETYLASE 9; INTERFERON INDUCIBLE DOUBLE STRANDED RNA DEPENDENT ACTIVATOR; LEUCINE RICH REPEAT KINASE 2; METHYLCROTONOYL COENZYME A CARBOXYLASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL BINDING CLATHRIN ASSEMBLY PROTEIN; PHOSPHOLIPASE A2; PROTEIN; PROTEIN KINASE WNK1; RETINOIC ACID INDUCED 1; SCAVENGER RECEPTOR B; SCAVENGER RECEPTOR CLASS B2; SERINE THREONINE KINASE 39; STARCH BINDING DOMAIN 1; STEM CELL ANTIGEN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SYNAPTOTAGMIN XIV; TAU PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACUOLAR PROTEIN SORTING ASSOCIATED PROTEIN 35; VELAFERMIN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CEREBELLAR ATAXIA; COMPUTER MODEL; COPY NUMBER VARIATION; DNA SEQUENCE; DYSTONIA; FRONTOTEMPORAL DEMENTIA; GENE DELETION; GENE DOSAGE; GENE EXPRESSION; GENE FREQUENCY; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC MARKER; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HEREDITARY MOTOR SENSORY NEUROPATHY; HOMOZYGOSITY; HUMAN; IMMUNE RESPONSE; LEUKOENCEPHALOPATHY; LINKAGE ANALYSIS; MULTIPLE SCLEROSIS; OPEN READING FRAME; PARKINSON DISEASE; PARKINSONISM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SPINOCEREBELLAR DEGENERATION; STROKE;

ANIMALS; EXOME; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; NERVOUS SYSTEM DISEASES; SEQUENCE ANALYSIS, DNA;

EID: 84862605504     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn3271     Document Type: Review

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