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Volumn 2, Issue 3, 2006, Pages 0316-0325

Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME VARIANT; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; FAMILY; FEASIBILITY STUDY; GENE IDENTIFICATION; GENE SEGREGATION; GENETIC VARIABILITY; GENOME; HERITABILITY; HUMAN; PHENOTYPE; QUANTITATIVE TRAIT; QUASI EXPERIMENTAL STUDY; SIBLING; TWINS; VALIDATION PROCESS; BIOLOGICAL MODEL; BODY HEIGHT; CHROMOSOME MAP; FAMILY HEALTH; GENETIC MARKER; STATISTICAL MODEL;

EID: 33645760679     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020041     Document Type: Article
Times cited : (452)

References (49)
  • 1
    • 84971185409 scopus 로고
    • The correlation between relatives on the supposition of Mendelian inheritance
    • Fisher RA (1918) The correlation between relatives on the supposition of Mendelian inheritance. Trans Roy Soc Edin 52: 399-433.
    • (1918) Trans Roy Soc Edin , vol.52 , pp. 399-433
    • Fisher, R.A.1
  • 5
    • 77956889208 scopus 로고
    • Recovery of interblock information when block sizes are unequal
    • Patterson HD, Thompson R (1971) Recovery of interblock information when block sizes are unequal. Biometrika 58: 545-555.
    • (1971) Biometrika , vol.58 , pp. 545-555
    • Patterson, H.D.1    Thompson, R.2
  • 6
    • 0017165430 scopus 로고
    • Extensions to pedigree analysis. III. Variance components by the scoring method
    • Lange K, Westlake J, Spence MA (1976) Extensions to pedigree analysis. III. Variance components by the scoring method. Ann Hum Genet 39: 485-491.
    • (1976) Ann Hum Genet , vol.39 , pp. 485-491
    • Lange, K.1    Westlake, J.2    Spence, M.A.3
  • 7
    • 0029564551 scopus 로고
    • Average information REML: An efficient algorithm for variance parameter estimation in linear mixed models
    • Gilmour AR, Thompson R, Cullis BR (1995) Average information REML: An efficient algorithm for variance parameter estimation in linear mixed models. Biometrics 51: 1440-1450.
    • (1995) Biometrics , vol.51 , pp. 1440-1450
    • Gilmour, A.R.1    Thompson, R.2    Cullis, B.R.3
  • 8
    • 0029051087 scopus 로고
    • Physical similarity and the equal-environment assumption in twin studies of psychiatric disorders
    • Hettema JM, Neale MC, Kendler KS (1995) Physical similarity and the equal-environment assumption in twin studies of psychiatric disorders. Behav Genet 25: 327-335.
    • (1995) Behav Genet , vol.25 , pp. 327-335
    • Hettema, J.M.1    Neale, M.C.2    Kendler, K.S.3
  • 9
    • 0027409708 scopus 로고
    • A test of the equal-environment assumption in twin studies of psychiatric illness
    • Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1993) A test of the equal-environment assumption in twin studies of psychiatric illness. Behav Genet 23: 21-27.
    • (1993) Behav Genet , vol.23 , pp. 21-27
    • Kendler, K.S.1    Neale, M.C.2    Kessler, R.C.3    Heath, A.C.4    Eaves, L.J.5
  • 10
  • 11
    • 0030046874 scopus 로고    scopus 로고
    • Variation in genetic identity among relatives
    • Guo SW (1996) Variation in genetic identity among relatives. Hum Hered 46: 61-70.
    • (1996) Hum Hered , vol.46 , pp. 61-70
    • Guo, S.W.1
  • 12
    • 0018849597 scopus 로고
    • The distribution of the fraction of the genome identical-by-descent in finite random mating populations
    • Stam P (1980) The distribution of the fraction of the genome identical-by-descent in finite random mating populations. Genet Res 35: 131-155.
    • (1980) Genet Res , vol.35 , pp. 131-155
    • Stam, P.1
  • 13
    • 0018663050 scopus 로고
    • Application of a recombination model in calculating the variance of sib pair genetic identity
    • Risch N, Lange K (1979) Application of a recombination model in calculating the variance of sib pair genetic identity. Ann Hum Genet 43: 177-186.
    • (1979) Ann Hum Genet , vol.43 , pp. 177-186
    • Risch, N.1    Lange, K.2
  • 14
    • 0018381740 scopus 로고
    • Variability in sib pair genetic identity
    • Suarez BK, Reich T, Fishman PM (1979) Variability in sib pair genetic identity. Hum Hered 29: 37-41.
    • (1979) Hum Hered , vol.29 , pp. 37-41
    • Suarez, B.K.1    Reich, T.2    Fishman, P.M.3
  • 15
    • 9144254700 scopus 로고    scopus 로고
    • Heritability of adult body height: A comparative study of twin cohorts in eight countries
    • Silventoinen K, Sammalisto S, Perola M, Boomsma DI, Cornes BK, et al. (2003) Heritability of adult body height: A comparative study of twin cohorts in eight countries. Twin Res 6: 399-408.
    • (2003) Twin Res , vol.6 , pp. 399-408
    • Silventoinen, K.1    Sammalisto, S.2    Perola, M.3    Boomsma, D.I.4    Cornes, B.K.5
  • 16
    • 31344466234 scopus 로고    scopus 로고
    • The estimation of genetic relationships using molecular markers and their efficiency in estimating heritability in natural populations
    • Thomas SC (2005) The estimation of genetic relationships using molecular markers and their efficiency in estimating heritability in natural populations. Philos Trans R Soc Lond B Biol Sci 360: 1457-1467.
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , pp. 1457-1467
    • Thomas, S.C.1
  • 17
    • 0033824478 scopus 로고    scopus 로고
    • Marker-inferred relatedness as a tool for detecting heritability in nature
    • Ritland K (2000) Marker-inferred relatedness as a tool for detecting heritability in nature. Mol Ecol 9: 1195-1204.
    • (2000) Mol Ecol , vol.9 , pp. 1195-1204
    • Ritland, K.1
  • 18
    • 0345718511 scopus 로고    scopus 로고
    • Estimation of pair-wise relatedness with molecular markers
    • Lynch M, Ritland K (1999) Estimation of pair-wise relatedness with molecular markers. Genetics 152: 1753-1766.
    • (1999) Genetics , vol.152 , pp. 1753-1766
    • Lynch, M.1    Ritland, K.2
  • 19
    • 0034980335 scopus 로고    scopus 로고
    • Analytic power calculation for QTL linkage analysis of small pedigrees
    • Rijsdijk FV, Hewitt JK, Sham PC (2001) Analytic power calculation for QTL linkage analysis of small pedigrees. Eur J Hum Genet 9: 335-340.
    • (2001) Eur J Hum Genet , vol.9 , pp. 335-340
    • Rijsdijk, F.V.1    Hewitt, J.K.2    Sham, P.C.3
  • 20
    • 0034987802 scopus 로고    scopus 로고
    • Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs
    • Sham PC, Purcell S (2001) Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs. Am J Hum Genet 68: 1527-1532.
    • (2001) Am J Hum Genet , vol.68 , pp. 1527-1532
    • Sham, P.C.1    Purcell, S.2
  • 21
    • 0035714498 scopus 로고    scopus 로고
    • Power of regression and maximum likelihood methods to map QTL from sib-pair and DZ twin data
    • Visscher PM, Hopper JL (2001) Power of regression and maximum likelihood methods to map QTL from sib-pair and DZ twin data. Ann Hum Genet 65: 583-601.
    • (2001) Ann Hum Genet , vol.65 , pp. 583-601
    • Visscher, P.M.1    Hopper, J.L.2
  • 22
    • 27744440128 scopus 로고    scopus 로고
    • Genome-wide identity-by-descent sharing among CEPH siblings
    • Gagnon A, Beise J, Vaupel JW (2005) Genome-wide identity-by-descent sharing among CEPH siblings. Genet Epidemiol 29: 215-224.
    • (2005) Genet Epidemiol , vol.29 , pp. 215-224
    • Gagnon, A.1    Beise, J.2    Vaupel, J.W.3
  • 23
    • 0025245437 scopus 로고
    • Multipoint analysis of human quantitative genetic variation
    • Goldgar DE (1990) Multipoint analysis of human quantitative genetic variation. Am J Hum Genet 47: 957-967.
    • (1990) Am J Hum Genet , vol.47 , pp. 957-967
    • Goldgar, D.E.1
  • 24
    • 0029933248 scopus 로고    scopus 로고
    • Proportion of the variation in genetic composition in backcrossing programs explained by genetic markers
    • Visscher PM (1996) Proportion of the variation in genetic composition in backcrossing programs explained by genetic markers. J Hered 87: 136-138.
    • (1996) J Hered , vol.87 , pp. 136-138
    • Visscher, P.M.1
  • 25
    • 0035235185 scopus 로고    scopus 로고
    • Genome partitioning and whole-genome analysis
    • Schork NJ (2001) Genome partitioning and whole-genome analysis. Adv Genet 42: 299-322.
    • (2001) Adv Genet , vol.42 , pp. 299-322
    • Schork, N.J.1
  • 26
    • 17444448466 scopus 로고    scopus 로고
    • Evidence for extensive transmission distortion in the human genome
    • Zollner S, Wen X, Hanchard NA, Herbert MA, Ober C, et al. (2004) Evidence for extensive transmission distortion in the human genome. Am J Hum Genet 74: 62-72.
    • (2004) Am J Hum Genet , vol.74 , pp. 62-72
    • Zollner, S.1    Wen, X.2    Hanchard, N.A.3    Herbert, M.A.4    Ober, C.5
  • 27
    • 84907319426 scopus 로고
    • Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions
    • Self SG, Liang KY (1987) Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions. J Am Stat Assoc 82: 605-610.
    • (1987) J Am Stat Assoc , vol.82 , pp. 605-610
    • Self, S.G.1    Liang, K.Y.2
  • 28
    • 0028641810 scopus 로고
    • Variance components testing in the longitudinal mixed effects model
    • Stram DO, Lee JW (1994) Variance components testing in the longitudinal mixed effects model. Biometrics 50: 1171-1177.
    • (1994) Biometrics , vol.50 , pp. 1171-1177
    • Stram, D.O.1    Lee, J.W.2
  • 30
    • 0347364727 scopus 로고    scopus 로고
    • GenomEUtwin: A strategy to identify genetic in.uences on health and disease
    • Peltonen L (2003) GenomEUtwin: A strategy to identify genetic in.uences on health and disease. Twin Res 6: 354-360.
    • (2003) Twin Res , vol.6 , pp. 354-360
    • Peltonen, L.1
  • 31
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • Risch N, Zhang H (1995) Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 268: 1584-1589.
    • (1995) Science , vol.268 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 32
    • 0029979336 scopus 로고    scopus 로고
    • Mapping quantitative trait loci with extreme discordant sib pairs: Sampling considerations
    • Risch NJ, Zhang H (1996) Mapping quantitative trait loci with extreme discordant sib pairs: Sampling considerations. Am J Hum Genet 58: 836-843.
    • (1996) Am J Hum Genet , vol.58 , pp. 836-843
    • Risch, N.J.1    Zhang, H.2
  • 33
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC (1972) The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2: 3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 34
    • 0033927466 scopus 로고    scopus 로고
    • Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sib-ship data
    • Sham PC, Cherny SS, Purcell S, Hewitt JK (2000) Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sib-ship data. Am J Hum Genet 66: 1616-1630.
    • (2000) Am J Hum Genet , vol.66 , pp. 1616-1630
    • Sham, P.C.1    Cherny, S.S.2    Purcell, S.3    Hewitt, J.K.4
  • 35
    • 0028225412 scopus 로고
    • Computation of identity-by-descent proportions shared by two siblings
    • Guo SW (1994) Computation of identity-by-descent proportions shared by two siblings. Am J Hum Genet 54: 1104-1109.
    • (1994) Am J Hum Genet , vol.54 , pp. 1104-1109
    • Guo, S.W.1
  • 36
    • 0029007702 scopus 로고
    • Proportion of genome shared identical by descent by relatives: Concept, computation, and applications
    • Guo SW (1995) Proportion of genome shared identical by descent by relatives: Concept, computation, and applications. Am J Hum Genet 56: 1468-1476.
    • (1995) Am J Hum Genet , vol.56 , pp. 1468-1476
    • Guo, S.W.1
  • 37
    • 0030026005 scopus 로고    scopus 로고
    • Gametogenesis processes and multilocus gene identity by descent
    • Guo SW (1996) Gametogenesis processes and multilocus gene identity by descent. Am J Hum Genet 58: 408-419.
    • (1996) Am J Hum Genet , vol.58 , pp. 408-419
    • Guo, S.W.1
  • 38
    • 0017459421 scopus 로고
    • The distribution of the proportion of the genome which is homozygous by descent in inbred individuals
    • Franklin IR (1977) The distribution of the proportion of the genome which is homozygous by descent in inbred individuals. Theor Popul Biol 11: 60-80.
    • (1977) Theor Popul Biol , vol.11 , pp. 60-80
    • Franklin, I.R.1
  • 39
    • 0027175843 scopus 로고
    • Variation in genetic composition in backcrossing programs
    • Hill WG (1993) Variation in genetic composition in backcrossing programs. J Hered 84: 212-213.
    • (1993) J Hered , vol.84 , pp. 212-213
    • Hill, W.G.1
  • 40
    • 0001701855 scopus 로고
    • The theoretical proportion of the donor genome in near-isogenic lines of self-fertilizers bred by backcrossing
    • Stam P, Zeven AC (1981) The theoretical proportion of the donor genome in near-isogenic lines of self-fertilizers bred by backcrossing. Euphytica 30: 227-238.
    • (1981) Euphytica , vol.30 , pp. 227-238
    • Stam, P.1    Zeven, A.C.2
  • 41
    • 8844280819 scopus 로고    scopus 로고
    • A combined linkage-physical map of the human genome
    • Kong X, Murphy K, Raj T, He C, White PS, et al. (2004) A combined linkage-physical map of the human genome. Am J Hum Genet 75: 1143-1148.
    • (2004) Am J Hum Genet , vol.75 , pp. 1143-1148
    • Kong, X.1    Murphy, K.2    Raj, T.3    He, C.4    White, P.S.5
  • 42
    • 0002532939 scopus 로고
    • On the "probable error" of a coefficient of correlation deduced from a small sample
    • Fisher RA (1921) On the "probable error" of a coefficient of correlation deduced from a small sample. Metron 1: 3-32.
    • (1921) Metron , vol.1 , pp. 3-32
    • Fisher, R.A.1
  • 43
    • 12244264435 scopus 로고    scopus 로고
    • Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
    • Purcell S, Cherny SS, Sham PC (2003) Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19: 149-150.
    • (2003) Bioinformatics , vol.19 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 44
    • 0033362023 scopus 로고    scopus 로고
    • A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: A maximum-likelihood combined linkage and association analysis in twins and their sibs
    • Zhu G, Duffy DL, Eldridge A, Grace M, Mayne C, et al. (1999) A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: A maximum-likelihood combined linkage and association analysis in twins and their sibs. Am J Hum Genet 65: 483-492.
    • (1999) Am J Hum Genet , vol.65 , pp. 483-492
    • Zhu, G.1    Duffy, D.L.2    Eldridge, A.3    Grace, M.4    Mayne, C.5
  • 45
    • 17944377388 scopus 로고    scopus 로고
    • Genetics of cognition: Outline of a collaborative twin study
    • Wright M, De Geus E, Ando J, Luciano M, Posthuma D, et al. (2001) Genetics of cognition: Outline of a collaborative twin study. Twin Res 4: 48-56.
    • (2001) Twin Res , vol.4 , pp. 48-56
    • Wright, M.1    De Geus, E.2    Ando, J.3    Luciano, M.4    Posthuma, D.5
  • 46
    • 0034806711 scopus 로고    scopus 로고
    • Height discordance in monozygotic females is not attributable to discordant inactivation of X-linked stature determining genes
    • Healey SC, Kirk KM, Hyland VJ, Munns CF, Henders AK, et al. (2001) Height discordance in monozygotic females is not attributable to discordant inactivation of X-linked stature determining genes. Twin Res 4: 19-24.
    • (2001) Twin Res , vol.4 , pp. 19-24
    • Healey, S.C.1    Kirk, K.M.2    Hyland, V.J.3    Munns, C.F.4    Henders, A.K.5
  • 47
    • 11144355855 scopus 로고    scopus 로고
    • A genome scan for eye color in 502 twin families: Most variation is due to a QTL on Chromosome 15q
    • Zhu G, Evans DM, Duffy DL, Montgomery GW, Medland SE, et al. (2004) A genome scan for eye color in 502 twin families: Most variation is due to a QTL on Chromosome 15q. Twin Res 7: 197-210.
    • (2004) Twin Res , vol.7 , pp. 197-210
    • Zhu, G.1    Evans, D.M.2    Duffy, D.L.3    Montgomery, G.W.4    Medland, S.E.5
  • 48
    • 28544449261 scopus 로고    scopus 로고
    • Sex-limited genome-wide linkage scan for body mass index in an unselected sample of 933 Australian Twin Families
    • Cornes BK, Medland SE, Morley KI, Ferreira MAR, Gordon S, et al. (2005) Sex-limited genome-wide linkage scan for body mass index in an unselected sample of 933 Australian Twin Families. Twin Res Hum Genet 8: 616-632.
    • (2005) Twin Res Hum Genet , vol.8 , pp. 616-632
    • Cornes, B.K.1    Medland, S.E.2    Morley, K.I.3    Ferreira, M.A.R.4    Gordon, S.5
  • 49
    • 0036338150 scopus 로고    scopus 로고
    • Merlin - Rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis GR, Cherny SS, Cookson WO, Cardon LR (2002) Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 30: 97-101.
    • (2002) Nat Genet , vol.30 , pp. 97-101
    • Abecasis, G.R.1    Cherny, S.S.2    Cookson, W.O.3    Cardon, L.R.4


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