Identification of the catalytic Mg2+ ion in the hepatitis delta virus ribozyme

Biochemistry

Volumn 52, Issue 3, 2013, Pages 557-567

  Chen, Ji ^a   Ganguly, Abir ^b,d   Miswan, Zulaika ^a   Hammes Schiffer, Sharon ^b   Bevilacqua, Philip C ^b,c   Golden, Barbara L ^a  

^a PURDUE UNIVERSITY   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ACTIVE STRUCTURES; CATALYTIC BASE; DIVALENT METAL ION; DOUBLE MUTANTS; HEPATITIS DELTA VIRUS; ISOSTERIC; KINETIC ANALYSIS; LEWIS ACID; NEGATIVE POTENTIAL; NUCLEOBASES; RIBOZYMES; RNA CLEAVAGE; WILD TYPES;

HYDRATION; METAL IONS; MOLECULAR DYNAMICS; NUCLEOPHILES; REACTION KINETICS; RNA;

VIRUSES;

HYDROCHLOROTHIAZIDE; HYDROXYL GROUP; LEWIS ACID; MAGNESIUM ION; NUCLEOPHILE; PROTON; RIBOZYME;

ARTICLE; CRYSTAL STRUCTURE; HEPATITIS DELTA VIRUS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTON TRANSPORT; STATIC ELECTRICITY; WILD TYPE;

BIOCATALYSIS; CATALYTIC DOMAIN; HEPATITIS DELTA VIRUS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MAGNESIUM; MOLECULAR DYNAMICS SIMULATION; MUTATION; RNA FOLDING; RNA STABILITY; RNA, CATALYTIC; RNA, VIRAL; STATIC ELECTRICITY; SURFACE PROPERTIES; WATER;

HEPATITIS DELTA VIRUS;

EID: 84872783878     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3013092     Document Type: Article

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