An active-site guanine participates in glms ribozyme catalysis in its protonated state

Journal of the American Chemical Society

Volumn 133, Issue 45, 2011, Pages 18388-18396

  Viladoms, Júlia ^a   Scott, Lincoln G ^b   Fedor, Martha J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Cassia LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACILLUS ANTHRACIS; CLEAVAGE KINETICS; FUNCTIONAL ASSAYS; GENERAL BASE; GENERAL BASE CATALYSIS; GUANOSINES; HYDROGEN BONDINGS; PH DEPENDENCE; PH-DEPENDENT; PROTONATED; PROTONATED STATE; RIBOZYMES; STRUCTURAL STUDIES; TRANSITION STATE; WILD TYPES;

BACTERIOLOGY; FLUORESCENCE; HYDROGEN; HYDROGEN BONDS; POSITIVE IONS; PROTONATION;

CATALYSIS;

AZAGUANOSINE; GUANINE; GUANOSINE; RIBOZYME;

ARTICLE; BACILLUS ANTHRACIS; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ASSAY; HYDROGEN BOND; NONHUMAN; PH; PKA;

BACILLUS ANTHRACIS; BIOCATALYSIS; CATALYTIC DOMAIN; GUANINE; MODELS, MOLECULAR; RNA, CATALYTIC;

EID: 80755123378     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja207426j     Document Type: Article

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