Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 765-775

  Verstraelen, Jessica ^a   Reichl, Stephan ^a  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

ABC transporter; Cell culture; Cornea; Drug absorption; In vitro model

Indexed keywords

1,2,3,4,6,7,12,12A OCTAHYDRO 6 ISOBUTYL 9 METHOXY 1,4 DIOXOPYRAZINO[1',2':1,6]PYRIDO[3,4 B]INDOLE 3 PROPANOIC ACID TERT BUTYL ESTER; BREAST CANCER RESISTANCE PROTEIN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3; RHODAMINE 123; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORNEA; CORNEA CELL; DRUG ABSORPTION; DRUG PENETRATION; EX VIVO STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; WESTERN BLOTTING;

ADMINISTRATION, OPHTHALMIC; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CACO-2 CELLS; CELLS, CULTURED; CORNEA; DRUG DELIVERY SYSTEMS; GENE EXPRESSION; HUMANS; MODELS, ANIMAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; POLYMERASE CHAIN REACTION; RABBITS; SPECIES SPECIFICITY; SWINE;

EID: 84872765110     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.10.007     Document Type: Article

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