Paracellular and passive transcellular permeability in immortalized human corneal epithelial cell culture model

European Journal of Pharmaceutical Sciences

Volumn 20, Issue 1, 2003, Pages 99-106

  Toropainen, Elisa ^a   Ranta, Veli Pekka ^a   Vellonen, Kati Sisko ^a   Palmgrén, Joni ^a   Talvitie, Anu ^a   Laavola, Mirka ^a   Suhonen, Pekka ^b   Hämäläinen, Kaisa Mari ^b   Auriola, Seppo ^a   Urtti, Arto ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b ORION CORPORATION   (Finland)

Author keywords

Cell culture model; Corneal epithelium; Drug penetration; Ocular drug delivery; Pore size; Blockers

Indexed keywords

CELL CULTURE; MECHANICAL PERMEABILITY; POLYETHYLENE GLYCOLS;

TRANSCELLULAR PERMEABILITY;

DRUG PRODUCTS;

ALPRENOLOL; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; COLLAGEN; ESTERASE; FLUORESCEIN; FLUORESCEIN DIACETATE; MACROGOL DERIVATIVE; METOPROLOL; NADOLOL; PINDOLOL; PROPRANOLOL; SOTALOL; TIMOLOL;

ANIMAL TISSUE; ARTICLE; CELL GROWTH; CELL IMMORTALIZATION; CELL MEMBRANE PERMEABILITY; CELL TRANSPORT; CONTROLLED STUDY; CORNEA; CORNEA EPITHELIUM; DEGRADATION; DENSITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG TRANSPORT; EFFUSION; ENZYME ACTIVITY; ENZYME ASSAY; EPITHELIUM CELL; EXPERIMENTAL MODEL; FEMALE; FILTER; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIPOPHILICITY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOLECULAR PROBE; NONHUMAN; PASSIVE TRANSPORT; POROSITY; PRIORITY JOURNAL; RABBIT;

EID: 10744229446     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(03)00173-8     Document Type: Article

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