Regulation of adipokine production in human adipose tissue by propionic acid

European Journal of Clinical Investigation

Volumn 40, Issue 5, 2010, Pages 401-407

  Al Lahham, Sa'Ad H ^a,b   Roelofsen, Han ^b   Priebe, Marion ^b   Weening, Desiree ^b   Dijkstra, Martijn ^b   Hoek, Annemieke ^b   Rezaee, Farhad ^b   Venema, Koen ^a,c   Vonk, Roel J ^b  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c TNO   (Netherlands)

Author keywords

Adiponectin; G protein coupled receptors; Human adipose tissue; Leptin; Propionic acid; Resistin

Indexed keywords

ADIPONECTIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 41; G PROTEIN COUPLED RECEPTOR 43; LEPTIN; MESSENGER RNA; PROPIONIC ACID; RESISTIN; UNCLASSIFIED DRUG; ADIPOCYTOKINE; PROPIONIC ACID DERIVATIVE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPLANT; FEMALE; HUMAN; HUMAN TISSUE; OMENTUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; TISSUE DISTRIBUTION; ADIPOSE TISSUE; DOSE RESPONSE; GENE EXPRESSION; METABOLISM; MIDDLE AGED; SECRETION (PROCESS);

ADIPOKINES; ADIPOSE TISSUE; ADULT; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION; HUMANS; MIDDLE AGED; PROPIONATES; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 77951222945     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2010.02278.x     Document Type: Article

References (37)

1. Higgins JA, Higbee DR, Donahoo WT, Brown IL, Bell ML, Bessesen DH. Resistant starch consumption promotes lipid oxidation. Nutr Metab 2004 1 : 8.
2. Higgins JA, Brown MA, Storlien LH. Consumption of resistant starch decreases postprandial lipogenesis in white adipose tissue of the rat. Nutr J 2006 5 : 25.
3. So PW, Yu WS, Kuo YT, Wasserfall C, Goldstone AP, Bell JD et al. Impact of resistant starch on body fat patterning and central appetite regulation. PLoS One 2007 2 : e1309.
4. Robertson MD, Bickerton AS, Dennis AL, Vidal H, Frayn KN. Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism. Am J Clin Nutr 2005 82 : 559 567.
5. Weickert MO, Mohlig M, Schofl C, Arafat AM, Otto B, Viehoff H et al. Cereal fiber improves whole-body insulin sensitivity in overweight and obese women. Diabetes Care 2006 29 : 775 780.
6. Keenan MJ, Zhou J, McCutcheon KL, Raggio AM, Bateman HG, Todd E et al. Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat. Obesity 2006 14 : 1523 1534.
7. Cummings JH, Pomare EW, Branch WJ, Nayor CP, Macfarlane GT. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 1987 28 : 1221 1227.
8. Hur EM, Kim KT. G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity. Cell Signal 2002 14 : 397 405.
9. Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 2003 278 : 11312 11319.
10. Le Poul E, Loison C, Struyf S, Springael JY, Lannoy V, Decobecq ME et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 2003 278 : 25481 25489.
11. Cook SI, Sellin JH. Review article: short chain fatty acids in health and disease. Aliment Pharmacol Ther 1998 12 : 499 507.
12. Xiong Y, Miyamoto N, Shibata K, Valasek MA, Motoike T, Kedzierski RM et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci USA 2004 101 : 1045 1050.
13. Hong YH, Nishimura Y, Hishikawa D, Tsuzuki H, Miyahara H, Gotoh C et al. Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology 2005 146 : 5092 5099.
14. Soliman M, Kimura K, Ahmed M, Yamaji D, Matsushita Y, Okamatsu-Ogura Y et al. Inverse regulation of leptin mRNA expression by short- and long-chain fatty acids in cultured bovine adipocytes. Domest Anim Endocrinol 2007 33 : 400 409.
15. Lee SH, Hossner KL. Coordinate regulation of ovine adipose tissue gene expression by propionate. J Anim Sci 2002 80 : 2840 2849.
16. Allen MS. Effects of diet on short-term regulation of feed intake by lactating dairy cattle. J Dairy Sci 2000 83 : 1598 1624.
17. Friedman JM. Obesity: causes and control of excess body fat. Nature 2009 459 : 340 342.
18. Rasouli N, Kern PA. Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab 2008 93 (Suppl. 1 S64 73.
19. Kusminski CM, da Silva NF, Creely SJ, Fisher FM, Harte AL, Baker AR et al. The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes. J Clin Endocrinol Metab 2007 92 : 270 276.
20. Bertolani C, Sancho-Bru P, Failli P, Bataller R, Aleffi S, DeFranco R et al. Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells. Am J Pathol 2006 169 : 2042 2053.
21. Qatanani M, Szwergold NR, Greaves DR, Ahima RS, Lazar MA. Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice. J Clin Invest 2009 119 : 531 539.
22. Hivert MF, Sullivan LM, Fox CS, Nathan DM, D'Agostino RB Sr., Wilson PW et al. Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance. J Clin Endocrinol Metab 2008 93 : 3165 3172.
23. Frankel DS, Vasan RS, D'Agostino RB Sr., Benjamin EJ, Levy D, Wang TJ et al. Resistin, adiponectin, and risk of heart failure the Framingham offspring study. J Am Coll Cardiol 2009 53 : 754 762.
24. Butler J, Kalogeropoulos A, Georgiopoulou V, de Rekeneire N, Rodondi N, Smith AL et al. Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study. Arterioscler Thromb Vasc Biol 2009 29 : 1144 1149.
25. Alvarez-Llamas G, Szalowska E, de Vries MP, Weening D, Landman K, Hoek A et al. Characterization of the human visceral adipose tissue secretome. Mol Cell Proteomics 2007 6 : 589 600.
26. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002 3 : RESEARCH0034.1 0034.11.
27. Farningham DA, Whyte CC. The role of propionate and acetate in the control of food intake in sheep. Br J Nutr 1993 70 : 37 46.
28. Boström EA, Tarkowski A, Bokarewa M. Resistin is stored in neutrophil granules being released upon challenge with inflammatory stimuli. Biochim Biophys Acta 2009 1793 : 1894 1900.
29. Tedelind S, Westberg F, Kjerrulf M, Vidal A. Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease. World J Gastroenterol 2007 13 : 2826 2832.
30. Stork LC, Ambruso DR, Wallner SF, Sambrano JE, Moscinski LC, Wilson HL et al. Pancytopenia in propionic acidemia: hematologic evaluation and studies of hematopoiesis in vitro. Pediatr Res 1986 20 : 783 788.
31. Wajner M, Santos KD, Schlottfeldt JL, Rocha MP, Wannmacher CM. Inhibition of mitogen-activated proliferation of human peripheral lymphocytes in vitro by propionic acid. Clin Sci 1999 96 : 99 103.
32. Hutchinson RJ, Bunnell K, Thoene JG. Suppression of granulopoietic progenitor cell proliferation by metabolites of the branched-chain amino acids. J Pediatr 1985 106 : 62 5.
33. Curi R, Bond JA, Calder PC, Newsholme EA. Propionate regulates lymphocyte proliferation and metabolism. Gen Pharmacol 1993 24 : 591 597.
34. Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006 444 : 860 867.
35. Curat CA, Wegner V, Sengenès C, Miranville A, Tonus C, Busse R et al. Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin. Diabetologia 2006 49 : 744 747.
36. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994 372 : 425 432.
37. Bergman EN. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol Rev 1990 70 : 567 590.