Modulation of methuselah expression targeted to Drosophila insulin-producing cells extends life and enhances oxidative stress resistance

Aging Cell

Volumn 12, Issue 1, 2013, Pages 121-129

  Gimenez, Luis E D ^a,d   Ghildyal, Parakashtha ^a,e   Fischer, Kathleen E ^b   Hu, Hongxiang ^a,f   Ja, William W ^c   Eaton, Benjamin A ^b   Wu, Yimin ^b   Austad, Steven N ^a,d   Ranjan, Ravi ^a,d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c University of Texas Health Science Center   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF OSLO   (Norway)

^f UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Aging; Drosophila; Endocrinology; Genetics; Insulin IGF 1signaling; Longevity; Neuroscience; Signaling

Indexed keywords

BETA ARRESTIN; COMPLEMENTARY DNA; COPPER ZINC SUPEROXIDE DISMUTASE; G PROTEIN COUPLED RECEPTOR; INSULIN; MANGANESE SUPEROXIDE DISMUTASE; METHUSELAH PROTEIN; PROTEIN KINASE B; SOMATOMEDIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG;

ARTICLE; BRAIN; DROSOPHILA; ENZYME ACTIVITY; FEMALE; INSULIN RELEASE; LONGEVITY; MALE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE;

ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; INSULIN; LONGEVITY; MALE; OXIDATIVE STRESS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSGENES;

EID: 84872607746     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12027     Document Type: Article

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