-
1
-
-
84856043672
-
A mathematical theory of communication
-
Shannon CE. 1948. A mathematical theory of communication. Bell Syst Tech J 27: 379-423.
-
(1948)
Bell Syst Tech J
, vol.27
, pp. 379-423
-
-
Shannon, C.E.1
-
2
-
-
84861548003
-
Bit by bit: the Darwinian basis of life
-
Joyce GF. 2012. Bit by bit: the Darwinian basis of life. PLoS Biol 10: e1001323.
-
(2012)
PLoS Biol
, vol.10
-
-
Joyce, G.F.1
-
3
-
-
0014937223
-
Central dogma of molecular biology
-
Crick F. 1970. Central dogma of molecular biology. Nature 227: 561-3.
-
(1970)
Nature
, vol.227
, pp. 561-563
-
-
Crick, F.1
-
4
-
-
84866747149
-
Next-generation digital information storage in DNA
-
Church GM, Gao Y, Kosuri S. 2012. Next-generation digital information storage in DNA. Science 337: 1628.
-
(2012)
Science
, vol.337
, pp. 1628
-
-
Church, G.M.1
Gao, Y.2
Kosuri, S.3
-
5
-
-
84861547994
-
Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences
-
Derr J, Manapat ML, Rajamani S, Leu K, et al. 2012. Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences. Nucleic Acids Res 40: 4711-22.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 4711-4722
-
-
Derr, J.1
Manapat, M.L.2
Rajamani, S.3
Leu, K.4
-
6
-
-
0037665961
-
Functional information: molecular messages
-
Szostak JW. 2003. Functional information: molecular messages. Nature 423: 689.
-
(2003)
Nature
, vol.423
, pp. 689
-
-
Szostak, J.W.1
-
8
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
-
Frommer M, McDonald LE, Millar DS, Collis CM, et al. 1992. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci USA 89: 1827-31.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
Collis, C.M.4
-
9
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW. 2003. The power and the promise of DNA methylation markers. Nat Rev Cancer 3: 253-66.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
11
-
-
77952967431
-
Direct detection of DNA methylation during single-molecule, real-time sequencing
-
Flusberg BA, Webster DR, Lee JH, Travers KJ, et al. 2010. Direct detection of DNA methylation during single-molecule, real-time sequencing. Nat Methods 7: 461-5.
-
(2010)
Nat Methods
, vol.7
, pp. 461-465
-
-
Flusberg, B.A.1
Webster, D.R.2
Lee, J.H.3
Travers, K.J.4
-
12
-
-
84862590549
-
Going beyond five bases in DNA sequencing
-
Korlach J, Turner SW. 2012. Going beyond five bases in DNA sequencing. Curr Opin Struct Biol 22: 251-61.
-
(2012)
Curr Opin Struct Biol
, vol.22
, pp. 251-261
-
-
Korlach, J.1
Turner, S.W.2
-
13
-
-
80054072119
-
The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA
-
Leu K, Obermayer B, Rajamani S, Gerland U, et al. 2011. The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA. Nucleic Acids Res 39: 8135-47.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 8135-8147
-
-
Leu, K.1
Obermayer, B.2
Rajamani, S.3
Gerland, U.4
-
14
-
-
77952562924
-
Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication
-
Rajamani S, Ichida JK, Antal T, Treco DA, et al. 2010. Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication. J Am Chem Soc 132: 5880-5.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 5880-5885
-
-
Rajamani, S.1
Ichida, J.K.2
Antal, T.3
Treco, D.A.4
-
15
-
-
75349085231
-
An in vitro translation, selection and amplification system for peptide nucleic acids
-
Brudno Y, Birnbaum ME, Kleiner RE, Liu DR. 2010. An in vitro translation, selection and amplification system for peptide nucleic acids. Nat Chem Biol 6: 148-55.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 148-155
-
-
Brudno, Y.1
Birnbaum, M.E.2
Kleiner, R.E.3
Liu, D.R.4
-
16
-
-
0035692230
-
A method to select chemically modified aptamers directly
-
Boiziau C, Toulme JJ. 2001. A method to select chemically modified aptamers directly. Antisense Nucleic Acid Drug Dev 11: 379-85.
-
(2001)
Antisense Nucleic Acid Drug Dev
, vol.11
, pp. 379-385
-
-
Boiziau, C.1
Toulme, J.J.2
-
18
-
-
0242415199
-
Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes
-
Rosenbaum DM, Liu DR. 2003. Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes. J Am Chem Soc 125: 13924-5.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 13924-13925
-
-
Rosenbaum, D.M.1
Liu, D.R.2
-
19
-
-
0029838624
-
PCR fidelity of Pfu DNA polymerase and other thermostable DNA polymerases
-
Cline J, Braman JC, Hogrefe HH. 1996. PCR fidelity of Pfu DNA polymerase and other thermostable DNA polymerases. Nucleic Acids Res 24: 3546-51.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 3546-3551
-
-
Cline, J.1
Braman, J.C.2
Hogrefe, H.H.3
-
20
-
-
25144486758
-
High fidelity TNA synthesis by Therminator polymerase
-
Ichida JK, Horhota A, Zou K, McLaughlin LW, et al. 2005. High fidelity TNA synthesis by Therminator polymerase. Nucleic Acids Res 33: 5219-25.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5219-5225
-
-
Ichida, J.K.1
Horhota, A.2
Zou, K.3
McLaughlin, L.W.4
-
21
-
-
68149136529
-
Polymerase engineering: towards the encoded synthesis of unnatural biopolymers
-
Loakes D, Holliger P. 2009. Polymerase engineering: towards the encoded synthesis of unnatural biopolymers. Chem Commun (Camb) 4619-31.
-
(2009)
Chem Commun (Camb)
, pp. 4619-4631
-
-
Loakes, D.1
Holliger, P.2
-
22
-
-
84860013215
-
Synthetic genetic polymers capable of heredity and evolution
-
Pinheiro VB, Taylor AI, Cozens C, Abramov M, et al. 2012. Synthetic genetic polymers capable of heredity and evolution. Science 336: 341-4.
-
(2012)
Science
, vol.336
, pp. 341-344
-
-
Pinheiro, V.B.1
Taylor, A.I.2
Cozens, C.3
Abramov, M.4
-
23
-
-
84861444019
-
A short adaptive path from DNA to RNA polymerases
-
Cozens C, Pinheiro VB, Vaisman A, Woodgate R, et al. 2012. A short adaptive path from DNA to RNA polymerases. Proc Natl Acad Sci USA 109: 8067-72.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 8067-8072
-
-
Cozens, C.1
Pinheiro, V.B.2
Vaisman, A.3
Woodgate, R.4
-
24
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl T. 1993. Instability and decay of the primary structure of DNA. Nature 362: 709-15.
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
25
-
-
84857411787
-
Y-family DNA polymerases and their role in tolerance of cellular DNA damage
-
Sale JE, Lehmann AR, Woodgate R. 2012. Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat Rev Mol Cell Biol 13: 141-52.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 141-152
-
-
Sale, J.E.1
Lehmann, A.R.2
Woodgate, R.3
-
26
-
-
2542525398
-
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution
-
Ghadessy FJ, Ramsay N, Boudsocq F, Loakes D, et al. 2004. Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Nat Biotechnol 22: 755-9.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 755-759
-
-
Ghadessy, F.J.1
Ramsay, N.2
Boudsocq, F.3
Loakes, D.4
-
27
-
-
34547769773
-
Molecular breeding of polymerases for amplification of ancient DNA
-
d'Abbadie M, Hofreiter M, Vaisman A, Loakes D, et al. 2007. Molecular breeding of polymerases for amplification of ancient DNA. Nat Biotechnol 25: 939-43.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 939-943
-
-
d'Abbadie, M.1
Hofreiter, M.2
Vaisman, A.3
Loakes, D.4
-
28
-
-
1642588255
-
Structures of mismatch replication errors observed in a DNA polymerase
-
Johnson SJ, Beese LS. 2004. Structures of mismatch replication errors observed in a DNA polymerase. Cell 116: 803-16.
-
(2004)
Cell
, vol.116
, pp. 803-816
-
-
Johnson, S.J.1
Beese, L.S.2
-
29
-
-
0033555718
-
The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 β-lactamase
-
Zaccolo M, Gherardi E. 1999. The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 β-lactamase. J Mol Biol 285: 775-83.
-
(1999)
J Mol Biol
, vol.285
, pp. 775-783
-
-
Zaccolo, M.1
Gherardi, E.2
-
30
-
-
0029869449
-
An approach of random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues
-
Zaccolo M, Williams DM, Brown DM, Gherardi E. 1996. An approach of random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. J Mol Biol 255: 589-603.
-
(1996)
J Mol Biol
, vol.255
, pp. 589-603
-
-
Zaccolo, M.1
Williams, D.M.2
Brown, D.M.3
Gherardi, E.4
-
31
-
-
0028245297
-
A universal nucleoside for use at ambiguous sites in DNA primers
-
Nichols R, Andrews PC, Zhang P, Bergstrom DE. 1994. A universal nucleoside for use at ambiguous sites in DNA primers. Nature 369: 492-3.
-
(1994)
Nature
, vol.369
, pp. 492-493
-
-
Nichols, R.1
Andrews, P.C.2
Zhang, P.3
Bergstrom, D.E.4
-
32
-
-
0027984280
-
5-Nitroindole as a universal base analogue
-
Loakes D, Brown DM. 1994. 5-Nitroindole as a universal base analogue. Nucleic Acids Res 22: 4039-43.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4039-4043
-
-
Loakes, D.1
Brown, D.M.2
-
33
-
-
0031577265
-
Stability and structure of DNA oligonucleotides containing non-specific base analogues
-
Loakes D, Hill F, Brown DM, Salisbury SA. 1997. Stability and structure of DNA oligonucleotides containing non-specific base analogues. J Mol Biol 270: 426-35.
-
(1997)
J Mol Biol
, vol.270
, pp. 426-435
-
-
Loakes, D.1
Hill, F.2
Brown, D.M.3
Salisbury, S.A.4
-
34
-
-
70350050801
-
Evolving a polymerase for hydrophobic base analogues
-
Loakes D, Gallego J, Pinheiro VB, Kool ET, et al. 2009. Evolving a polymerase for hydrophobic base analogues. J Am Chem Soc 131: 14827-37.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 14827-14837
-
-
Loakes, D.1
Gallego, J.2
Pinheiro, V.B.3
Kool, E.T.4
-
35
-
-
6944225455
-
Understanding nucleic acids using synthetic chemistry
-
Benner SA. 2004. Understanding nucleic acids using synthetic chemistry. Acc Chem Res 37: 784-97.
-
(2004)
Acc Chem Res
, vol.37
, pp. 784-797
-
-
Benner, S.A.1
-
36
-
-
0025008851
-
Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet
-
Piccirilli JA, Krauch T, Moroney SE, Benner SA. 1990. Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet. Nature 343: 33-7.
-
(1990)
Nature
, vol.343
, pp. 33-37
-
-
Piccirilli, J.A.1
Krauch, T.2
Moroney, S.E.3
Benner, S.A.4
-
38
-
-
80053068450
-
Amplification, mutation and sequencing of a six-letter synthetic genetic system
-
Yang Z, Chen F, Alvarado JB, Benner SA. 2011. Amplification, mutation and sequencing of a six-letter synthetic genetic system. J Am Chem Soc 133: 15105-12.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 15105-15112
-
-
Yang, Z.1
Chen, F.2
Alvarado, J.B.3
Benner, S.A.4
-
39
-
-
79955984480
-
Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity
-
Chen F, Yang Z, Yan M, Alvarado JB, et al. 2011. Recognition of an expanded genetic alphabet by type-II restriction endonucleases and their application to analyze polymerase fidelity. Nucleic Acids Res 39: 3949-61.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 3949-3961
-
-
Chen, F.1
Yang, Z.2
Yan, M.3
Alvarado, J.B.4
-
40
-
-
77955027700
-
Artificial genetic systems: self-avoiding DNA in PCR and multiplexed PCR
-
Hoshika S, Chen F, Leal NA, Benner SA. 2010. Artificial genetic systems: self-avoiding DNA in PCR and multiplexed PCR. Angew Chem Int Ed Engl 49: 5554-7.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 5554-5557
-
-
Hoshika, S.1
Chen, F.2
Leal, N.A.3
Benner, S.A.4
-
41
-
-
67849130960
-
Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment
-
Minakawa N, Ogata S, Takahashi M, Matsuda A. 2009. Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment. J Am Chem Soc 131: 1644-5.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 1644-1645
-
-
Minakawa, N.1
Ogata, S.2
Takahashi, M.3
Matsuda, A.4
-
42
-
-
80052956657
-
New imidazopyridopyrimidine:naphthyridine base-pairing motif, ImN(N):NaO(O), consisting of a DAAD:ADDA hydrogen bonding pattern, markedly stabilize DNA duplexes
-
Kuramoto K, Tarashima N, Hirama Y, Kikuchi Y, et al. 2011. New imidazopyridopyrimidine:naphthyridine base-pairing motif, ImN(N):NaO(O), consisting of a DAAD:ADDA hydrogen bonding pattern, markedly stabilize DNA duplexes. Chem Commun (Camb) 47: 10818-20.
-
(2011)
Chem Commun (Camb)
, vol.47
, pp. 10818-10820
-
-
Kuramoto, K.1
Tarashima, N.2
Hirama, Y.3
Kikuchi, Y.4
-
43
-
-
73049107584
-
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo-) DNA polymerase
-
Ogata S, Takahashi M, Minakawa N, Matsuda A. 2009. Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo-) DNA polymerase. Nucleic Acids Res 37: 5602-9.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5602-5609
-
-
Ogata, S.1
Takahashi, M.2
Minakawa, N.3
Matsuda, A.4
-
44
-
-
69049104260
-
The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation
-
Hwang GT, Hari Y, Romesberg FE. 2009. The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation. Nucleic Acids Res 37: 4757-63.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4757-4763
-
-
Hwang, G.T.1
Hari, Y.2
Romesberg, F.E.3
-
46
-
-
84862857430
-
KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry
-
Betz K, Malyshev DA, Lavergne T, Welte W, et al. 2012. KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Nat Chem Biol 8: 612-4.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 612-614
-
-
Betz, K.1
Malyshev, D.A.2
Lavergne, T.3
Welte, W.4
-
47
-
-
83055197046
-
Site-specific labelling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs
-
Seo YJ, Malyshev DA, Lavergne T, Ordoukhanian P, et al. 2011. Site-specific labelling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs. J Am Chem Soc 133: 19878-88.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 19878-19888
-
-
Seo, Y.J.1
Malyshev, D.A.2
Lavergne, T.3
Ordoukhanian, P.4
-
48
-
-
67849087122
-
Transcription of an expanded genetic alphabet
-
Seo YJ, Matsuda S, Romesberg FE. 2009. Transcription of an expanded genetic alphabet. J Am Chem Soc 131: 5046-7.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 5046-5047
-
-
Seo, Y.J.1
Matsuda, S.2
Romesberg, F.E.3
-
49
-
-
59649091247
-
An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules
-
Kimoto M, Kawai R, Mitsui T, Yokoyama S, et al. 2009. An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules. Nucleic Acids Res 37: e14.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Kimoto, M.1
Kawai, R.2
Mitsui, T.3
Yokoyama, S.4
-
50
-
-
84867380819
-
PCR amplification and transcription for site-specific labeling of large RNA molecules by a two-unnatural-base-pair system
-
Kimoto M, Yamashige R, Yokoyama S, Hirao I. 2012. PCR amplification and transcription for site-specific labeling of large RNA molecules by a two-unnatural-base-pair system. J Nucleic Acids 2012: 230943.
-
(2012)
J Nucleic Acids
, vol.2012
, pp. 230943
-
-
Kimoto, M.1
Yamashige, R.2
Yokoyama, S.3
Hirao, I.4
-
51
-
-
77950827602
-
A unique fluorescent base analogue for the expansion of the genetic alphabet
-
Kimoto M, Mitsui T, Yokoyama S, Hirao I. 2010. A unique fluorescent base analogue for the expansion of the genetic alphabet. J Am Chem Soc 132: 4988-9.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 4988-4989
-
-
Kimoto, M.1
Mitsui, T.2
Yokoyama, S.3
Hirao, I.4
-
52
-
-
84858974138
-
Site-specific incorporation of functional components into RNA by an unnatural base pair transcription system
-
Morohashi N, Kimoto M, Sato A, Kawai R, et al. 2012. Site-specific incorporation of functional components into RNA by an unnatural base pair transcription system. Molecules 17: 2855-76.
-
(2012)
Molecules
, vol.17
, pp. 2855-2876
-
-
Morohashi, N.1
Kimoto, M.2
Sato, A.3
Kawai, R.4
-
54
-
-
78049369185
-
A new unnatural base pair system between fluorophore and quencher base analogues for nucleic acid-based imaging technology
-
Kimoto M, Mitsui T, Yamashige R, Sato A, et al. 2010. A new unnatural base pair system between fluorophore and quencher base analogues for nucleic acid-based imaging technology. J Am Chem Soc 132: 15418-26.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 15418-15426
-
-
Kimoto, M.1
Mitsui, T.2
Yamashige, R.3
Sato, A.4
-
57
-
-
76649140481
-
Exotic DNAs made of nonnatural bases and natural phosphodiester bonds
-
Chiba J, Inouye M. 2010. Exotic DNAs made of nonnatural bases and natural phosphodiester bonds. Chem Biodivers 7: 259-82.
-
(2010)
Chem Biodivers
, vol.7
, pp. 259-282
-
-
Chiba, J.1
Inouye, M.2
-
58
-
-
0034326611
-
A novel copper-mediated DNA base pair
-
Meggers E, Holland PL, Tolman WB, Romesberg FE, et al. 2000. A novel copper-mediated DNA base pair. J Am Chem Soc 122: 10714-5.
-
(2000)
J Am Chem Soc
, vol.122
, pp. 10714-10715
-
-
Meggers, E.1
Holland, P.L.2
Tolman, W.B.3
Romesberg, F.E.4
-
59
-
-
77956524341
-
Incorporation of thymine nucleotides by DNA polymerases through T-Hg(II)-T base pairing
-
Urata H, Yamaguchi E, Funai T, Matsumura Y, et al. 2010. Incorporation of thymine nucleotides by DNA polymerases through T-Hg(II)-T base pairing. Angew Chem Int Ed 49: 6516-9.
-
(2010)
Angew Chem Int Ed
, vol.49
, pp. 6516-6519
-
-
Urata, H.1
Yamaguchi, E.2
Funai, T.3
Matsumura, Y.4
-
61
-
-
80053292275
-
Reversible bond formation enables the replication and amplification of a crosslinking salen complex as an orthogonal base pair
-
Kaul C, Muller M, Wagner M, Schneider S, et al. 2011. Reversible bond formation enables the replication and amplification of a crosslinking salen complex as an orthogonal base pair. Nat Chem 3: 794-800.
-
(2011)
Nat Chem
, vol.3
, pp. 794-800
-
-
Kaul, C.1
Muller, M.2
Wagner, M.3
Schneider, S.4
-
62
-
-
24744447201
-
Polymerase evolution: efforts toward expansion of the genetic code
-
Leconte AM, Chen L, Romesberg FE. 2005. Polymerase evolution: efforts toward expansion of the genetic code. J Am Chem Soc 127: 12470-1.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 12470-12471
-
-
Leconte, A.M.1
Chen, L.2
Romesberg, F.E.3
-
63
-
-
66149108671
-
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions
-
Powner MW, Gerland B, Sutherland JD. 2009. Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions. Nature 459: 239-42.
-
(2009)
Nature
, vol.459
, pp. 239-242
-
-
Powner, M.W.1
Gerland, B.2
Sutherland, J.D.3
-
64
-
-
84865441103
-
Multicomponent assembly of proposed DNA precursors in water
-
Powner MW, Zheng SL, Szostak JW. 2012. Multicomponent assembly of proposed DNA precursors in water. J Am Chem Soc 134: 13889-95.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 13889-13895
-
-
Powner, M.W.1
Zheng, S.L.2
Szostak, J.W.3
-
65
-
-
80052147758
-
Carbonaceous meteorites contain a wide range of extraterrestrial nucleobases
-
Callahan MP, Smith KE, Cleaves HJ II, Ruzicka J, et al. 2011. Carbonaceous meteorites contain a wide range of extraterrestrial nucleobases. Proc Natl Acad Sci USA 108: 13995-8.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 13995-13998
-
-
Callahan, M.P.1
Smith, K.E.2
Cleaves II, H.J.3
Ruzicka, J.4
-
66
-
-
0345304414
-
Why are there four letters in the genetic alphabet
-
Szathmary E. 2003. Why are there four letters in the genetic alphabet? Nat Rev Genet 4: 995-1001.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 995-1001
-
-
Szathmary, E.1
-
67
-
-
0033581938
-
A ribozyme that lacks cytidine
-
Rogers J, Joyce GF. 1999. A ribozyme that lacks cytidine. Nature 402: 323-5.
-
(1999)
Nature
, vol.402
, pp. 323-325
-
-
Rogers, J.1
Joyce, G.F.2
-
68
-
-
0035032445
-
The effect of cytidine on the structure and function of an RNA ligase ribozyme
-
Rogers J, Joyce GF. 2001. The effect of cytidine on the structure and function of an RNA ligase ribozyme. RNA 7: 395-404.
-
(2001)
RNA
, vol.7
, pp. 395-404
-
-
Rogers, J.1
Joyce, G.F.2
-
69
-
-
0037180804
-
A ribozyme composed of only two different nucleotides
-
Reader JS, Joyce GF. 2002. A ribozyme composed of only two different nucleotides. Nature 420: 841-4.
-
(2002)
Nature
, vol.420
, pp. 841-844
-
-
Reader, J.S.1
Joyce, G.F.2
-
71
-
-
0025871535
-
Four letters in the genetic alphabet: a frozen evolutionary optimum
-
Szathmary E. 1991. Four letters in the genetic alphabet: a frozen evolutionary optimum? Proc Biol Sci 245: 91-9.
-
(1991)
Proc Biol Sci
, vol.245
, pp. 91-99
-
-
Szathmary, E.1
-
72
-
-
0026520507
-
What is the optimum size for the genetic alphabet
-
Szathmary E. 1992. What is the optimum size for the genetic alphabet? Proc Natl Acad Sci USA 89: 2614-8.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 2614-2618
-
-
Szathmary, E.1
-
73
-
-
0036401375
-
A parity code interpretation of nucleotide alphabet composition
-
Mac Donaill DA. 2002. A parity code interpretation of nucleotide alphabet composition. Chem Commun (Camb) 2062-3.
-
(2002)
Chem Commun (Camb)
, pp. 2062-2063
-
-
Mac Donaill, D.A.1
-
74
-
-
0142135400
-
Why nature chose A, C, G and U/T: an error-coding perspective of nucleotide alphabet composition
-
Mac Donaill DA. 2003. Why nature chose A, C, G and U/T: an error-coding perspective of nucleotide alphabet composition. Orig Life Evol Biosph 33: 433-55.
-
(2003)
Orig Life Evol Biosph
, vol.33
, pp. 433-455
-
-
Mac Donaill, D.A.1
-
75
-
-
0344326234
-
Chemical etiology of nucleic acid structure
-
Eschenmoser A. 1999. Chemical etiology of nucleic acid structure. Science 284: 2118-24.
-
(1999)
Science
, vol.284
, pp. 2118-2124
-
-
Eschenmoser, A.1
-
76
-
-
84855714032
-
Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate
-
Maiti M, Siegmund V, Abramov M, Lescrinier E, et al. 2011. Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate. Chemistry 18: 869-79.
-
(2011)
Chemistry
, vol.18
, pp. 869-879
-
-
Maiti, M.1
Siegmund, V.2
Abramov, M.3
Lescrinier, E.4
-
77
-
-
75449088431
-
Nucleic acids with a six-membered 'carbohydrate' mimic in the backbone
-
Herdewijn P. 2010. Nucleic acids with a six-membered 'carbohydrate' mimic in the backbone. Chem Biodivers 7: 1-59.
-
(2010)
Chem Biodivers
, vol.7
, pp. 1-59
-
-
Herdewijn, P.1
-
78
-
-
0035997351
-
Active site tightness and substrate fit in DNA replication
-
Kool ET. 2002. Active site tightness and substrate fit in DNA replication. Annu Rev Biochem 71: 191-219.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 191-219
-
-
Kool, E.T.1
-
79
-
-
0037388383
-
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
-
Johnson SJ, Taylor JS, Beese LS. 2003. Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. Proc Natl Acad Sci USA 100: 3895-900.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3895-3900
-
-
Johnson, S.J.1
Taylor, J.S.2
Beese, L.S.3
-
80
-
-
0037471633
-
DNA polymerase-mediated DNA synthesis on a TNA template
-
Chaput JC, Ichida JK, Szostak JW. 2003. DNA polymerase-mediated DNA synthesis on a TNA template. J Am Chem Soc 125: 856-7.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 856-857
-
-
Chaput, J.C.1
Ichida, J.K.2
Szostak, J.W.3
-
81
-
-
0043210727
-
TNA synthesis by DNA polymerases
-
Chaput JC, Szostak JW. 2003. TNA synthesis by DNA polymerases. J Am Chem Soc 125: 9274-5.
-
(2003)
J Am Chem Soc
, vol.125
, pp. 9274-9275
-
-
Chaput, J.C.1
Szostak, J.W.2
-
82
-
-
84863116739
-
Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor
-
Yu H, Zhang S, Chaput JC. 2012. Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor. Nat Chem 4: 183-7.
-
(2012)
Nat Chem
, vol.4
, pp. 183-187
-
-
Yu, H.1
Zhang, S.2
Chaput, J.C.3
-
83
-
-
84867498478
-
The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion
-
Martin-Pintado N, Yahyaee-Anzahaee M, Campos-Olivas R, Noronha AM, et al. 2012. The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion. Nucleic Acids Res 40: 9329-39.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 9329-9339
-
-
Martin-Pintado, N.1
Yahyaee-Anzahaee, M.2
Campos-Olivas, R.3
Noronha, A.M.4
-
84
-
-
77952302811
-
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility
-
Watts JK, Martin-Pintado N, Gomez-Pinto I, Schwartzentruber J, et al. 2010. Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility. Nucleic Acids Res 38: 2498-511.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2498-2511
-
-
Watts, J.K.1
Martin-Pintado, N.2
Gomez-Pinto, I.3
Schwartzentruber, J.4
-
85
-
-
0028352571
-
Hybridization properties of oligoarabinonucleotides
-
Giannaris PA, Damha MJ. 1994. Hybridization properties of oligoarabinonucleotides. Can J Chem 72: 909-18.
-
(1994)
Can J Chem
, vol.72
, pp. 909-918
-
-
Giannaris, P.A.1
Damha, M.J.2
-
86
-
-
11944254904
-
Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues
-
Wu T, Orgel LE. 1992. Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues. J Am Chem Soc 114: 7963-9.
-
(1992)
J Am Chem Soc
, vol.114
, pp. 7963-7969
-
-
Wu, T.1
Orgel, L.E.2
-
87
-
-
0027105556
-
Nonenzymatic template-directed synthesis on oligodeoxycytidylate sequences in hairpin oligonucleotides
-
Wu T, Orgel LE. 1992. Nonenzymatic template-directed synthesis on oligodeoxycytidylate sequences in hairpin oligonucleotides. J Am Chem Soc 114: 317-22.
-
(1992)
J Am Chem Soc
, vol.114
, pp. 317-322
-
-
Wu, T.1
Orgel, L.E.2
-
88
-
-
70349923765
-
Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5′-phosphorimidazolide monomers
-
Schrum JP, Ricardo A, Krishnamurthy M, Blain JC, et al. 2009. Efficient and rapid template-directed nucleic acid copying using 2'-amino-2', 3'-dideoxyribonucleoside-5′-phosphorimidazolide monomers. J Am Chem Soc 131: 14560-70.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 14560-14570
-
-
Schrum, J.P.1
Ricardo, A.2
Krishnamurthy, M.3
Blain, J.C.4
-
89
-
-
0032584219
-
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides
-
Astatke M, Ng K, Grindley ND, Joyce CM. 1998. A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides. Proc Natl Acad Sci USA 95: 3402-7.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3402-3407
-
-
Astatke, M.1
Ng, K.2
Grindley, N.D.3
Joyce, C.M.4
-
90
-
-
0034979126
-
Hydrogen bonding, base stacking, and steric effects in DNA replication
-
Kool ET. 2001. Hydrogen bonding, base stacking, and steric effects in DNA replication. Annu Rev Biophys Biomol Struct 30: 1-22.
-
(2001)
Annu Rev Biophys Biomol Struct
, vol.30
, pp. 1-22
-
-
Kool, E.T.1
-
91
-
-
34247868854
-
Polymerase-directed synthesis of 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acids
-
Peng CG, Damha MJ. 2007. Polymerase-directed synthesis of 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acids. J Am Chem Soc 129: 5310-1.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 5310-5311
-
-
Peng, C.G.1
Damha, M.J.2
-
92
-
-
19944428130
-
Direct in vitro selection of a 2'-O-methyl aptamer to VEGF
-
Burmeister PE, Lewis SD, Silva RF, Preiss JR, et al. 2005. Direct in vitro selection of a 2'-O-methyl aptamer to VEGF. Chem Biol 12: 25-33.
-
(2005)
Chem Biol
, vol.12
, pp. 25-33
-
-
Burmeister, P.E.1
Lewis, S.D.2
Silva, R.F.3
Preiss, J.R.4
-
93
-
-
84856862481
-
Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids
-
Gupta P, Muse O, Rozners E. 2012. Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids. Biochemistry 51: 63-73.
-
(2012)
Biochemistry
, vol.51
, pp. 63-73
-
-
Gupta, P.1
Muse, O.2
Rozners, E.3
-
94
-
-
80053321034
-
Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA
-
Gupta P, Zengeya T, Rozners E. 2011. Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA. Chem Commun (Camb) 47: 11125-7.
-
(2011)
Chem Commun (Camb)
, vol.47
, pp. 11125-11127
-
-
Gupta, P.1
Zengeya, T.2
Rozners, E.3
-
95
-
-
58149153173
-
G-C quartet - a DNA-inspired Janus-GC heterocycle: synthesis, structural analysis, and self-organization
-
Asadi A, Patrick BO, Perrin DM. 2008. G-C quartet - a DNA-inspired Janus-GC heterocycle: synthesis, structural analysis, and self-organization. J Am Chem Soc 130: 12860-1.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 12860-12861
-
-
Asadi, A.1
Patrick, B.O.2
Perrin, D.M.3
-
96
-
-
84861639761
-
Different superstructures formed by Janus-type nucleosides
-
Zhao H, Huang W, Wu X, Xing Z, et al. 2012. Different superstructures formed by Janus-type nucleosides. Chem Commun (Camb) 48: 6097-9.
-
(2012)
Chem Commun (Camb)
, vol.48
, pp. 6097-6099
-
-
Zhao, H.1
Huang, W.2
Wu, X.3
Xing, Z.4
-
97
-
-
84865286097
-
The XNA world: progress towards replication and evolution of synthetic genetic polymers
-
Pinheiro VB, Holliger P. 2012. The XNA world: progress towards replication and evolution of synthetic genetic polymers. Curr Opin Chem Biol 16: 245-52.
-
(2012)
Curr Opin Chem Biol
, vol.16
, pp. 245-252
-
-
Pinheiro, V.B.1
Holliger, P.2
-
98
-
-
0037140939
-
Recognition of HNA and 1,5-anhydrohexitol nucleotides by DNA metabolizing enzymes
-
Vastmans K, Rozenski J, Van Aerschot A, Herdewijn P. 2002. Recognition of HNA and 1, 5-anhydrohexitol nucleotides by DNA metabolizing enzymes. Biochim Biophys Acta 1597: 115-22.
-
(2002)
Biochim Biophys Acta
, vol.1597
, pp. 115-122
-
-
Vastmans, K.1
Rozenski, J.2
Van Aerschot, A.3
Herdewijn, P.4
-
99
-
-
84865526525
-
Designing chemically modified oligonucleotides for targeted gene silencing
-
Deleavey GF, Damha MJ. 2012. Designing chemically modified oligonucleotides for targeted gene silencing. Chem Biol 19: 937-54.
-
(2012)
Chem Biol
, vol.19
, pp. 937-954
-
-
Deleavey, G.F.1
Damha, M.J.2
-
100
-
-
58549109007
-
Potent inhibition of microRNA in vivo without degradation
-
Davis S, Propp S, Freier SM, Jones LE, et al. 2009. Potent inhibition of microRNA in vivo without degradation. Nucleic Acids Res 37: 70-7.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 70-77
-
-
Davis, S.1
Propp, S.2
Freier, S.M.3
Jones, L.E.4
-
101
-
-
34447559698
-
Duplex formation of the simplified nucleic acid GNA
-
Schlegel MK, Peritz AE, Kittigowittana K, Zhang L, et al. 2007. Duplex formation of the simplified nucleic acid GNA. Chembiochem 8: 927-32.
-
(2007)
Chembiochem
, vol.8
, pp. 927-932
-
-
Schlegel, M.K.1
Peritz, A.E.2
Kittigowittana, K.3
Zhang, L.4
-
103
-
-
77950372750
-
Xenobiology: a new form of life as the ultimate biosafety tool
-
Schmidt M. 2010. Xenobiology: a new form of life as the ultimate biosafety tool. BioEssays 32: 322-31.
-
(2010)
BioEssays
, vol.32
, pp. 322-331
-
-
Schmidt, M.1
-
104
-
-
67650103200
-
Toward safe genetically modified organisms through the chemical diversification of nucleic acids
-
Herdewijn P, Marliere P. 2009. Toward safe genetically modified organisms through the chemical diversification of nucleic acids. Chem Biodivers 6: 791-808.
-
(2009)
Chem Biodivers
, vol.6
, pp. 791-808
-
-
Herdewijn, P.1
Marliere, P.2
-
105
-
-
84862098806
-
Ligand-dependent exponential amplification of a self-replicating L-RNA enzyme
-
Olea C Jr, Horning DP, Joyce GF. 2012. Ligand-dependent exponential amplification of a self-replicating L-RNA enzyme. J Am Chem Soc 134: 8050-3.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 8050-8053
-
-
Olea Jr., C.1
Horning, D.P.2
Joyce, G.F.3
-
106
-
-
0029758370
-
Mirror-design of L-oligonucleotide ligands binding to L-arginine
-
Nolte A, Kluszmann S, Bald R, Erdmann VA, et al. 1996. Mirror-design of L-oligonucleotide ligands binding to L-arginine. Nat Biotech 14: 1116-9.
-
(1996)
Nat Biotech
, vol.14
, pp. 1116-1119
-
-
Nolte, A.1
Kluszmann, S.2
Bald, R.3
Erdmann, V.A.4
-
107
-
-
0029758369
-
Mirror-image RNA that binds D-adenosine
-
Kluszmann S, Nolte A, Bald R, Erdmann VA, et al. 1996. Mirror-image RNA that binds D-adenosine. Nat Biotech 14: 1112-5.
-
(1996)
Nat Biotech
, vol.14
, pp. 1112-1115
-
-
Kluszmann, S.1
Nolte, A.2
Bald, R.3
Erdmann, V.A.4
|