Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: Potential epigenetic mechanisms in gene transcription in Aβ production

Neurobiology of Aging

Volumn 34, Issue 4, 2013, Pages 1069-1079

  Gu, Xinling ^a   Sun, Jing ^a   Li, Shen ^a   Wu, Xiangmei ^a   Li, Liang ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid ; DNA methylation; Histone acetylation; Nuclear factor B; Oxidative stress; SH SY5Y cell; Specific protein 1

Indexed keywords

AMYLOID BETA PROTEIN; BETA SECRETASE 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA METHYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE; HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE P300; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SYNAPSIN I; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APP GENE; ARTICLE; BACE1 GENE; BINDING AFFINITY; CELL LEVEL; CONTROLLED STUDY; DNA BINDING; DNA DEMETHYLATION; DNA METHYLATION; DOWN REGULATION; ENZYME REGULATION; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HISTONE HYPERACETYLATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SH SY5Y CELL; TRANSCRIPTION INITIATION;

ACETYLATION; AMYLOID BETA-PEPTIDES; CELL LINE; DNA METHYLATION; EPIGENESIS, GENETIC; HISTONES; HUMANS; NEURONS; OXIDATIVE STRESS; TRANSCRIPTION, GENETIC;

EID: 84872305918     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.10.013     Document Type: Article

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