Transfection of CYP4A1 cDNA increases vascular reactivity in renal interlobar arteries

American Journal of Physiology - Renal Physiology

Volumn 284, Issue 1 53-1, 2003, Pages

  Kaide, Jun Ichi ^a   Wang, Mong Heng ^a   Wang, Ji Shi ^a   Zhang, Fan ^a   Gopal, V Raj ^b   Falck, John R ^b   Nasjletti, Alberto ^a   Laniado Schwartzman, Michal ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

20 hydroxyeicosatetraenoic acid; Arachidonic acid; Cytochrome P 450; Phenylephrine

Indexed keywords

20 HYDROXYEICOSA 6,15 DIENOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; ARACHIDIC ACID; ARACHIDONIC ACID DERIVATIVE; CALCIUM ACTIVATED POTASSIUM CHANNEL; COMPLEMENTARY DNA; CYTOCHROME P450 4A; CYTOCHROME P450 4A1; N METHYLSULFONYL 12,12 DIBROMODOCEC 11 ENAMIDE; PHENYLEPHRINE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DNA TRANSFECTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT; RENAL ARTERY; VASCULAR SMOOTH MUSCLE;

EID: 0037215171     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00249.2002     Document Type: Article

References (29)

1. Alonso-Galicia M, Falck JR, Reddy KM, and Roman RJ. 20-HETE agonists and antagonists in the renal circulation. Am J Physiol Renal Physiol 277: F790-F796, 1999.
2. Birks EK, Bousamara M, Presberg K, Marsh JA, Effros JA, and Jacobs ER. Human pulmonary arteries dilate to 20-HETE, an endogenous eicosanoid of lung tissue. Am J Physiol Lung Cell Mol Physiol 272: L823-L829, 1997.
3. Carroll MA, Balazy M, Huang DD, Rybalova S, Falck JR, and McGiff JC. Cytochrome P450-derived renal HETEs: Storage and release. Kidney Int 51: 1696-1702, 1997.
4. Carroll MA, Pilar Garcia M, Falck JR, and McGiff JC. Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites. J Pharmacol Exp Ther 260: 104-109, 1992.
5. Chu ZM, Croft KD, Kingsbury DA, Falck JR, Reddy KM, and Beilin LJ. Cytochrome P450 metabolites of arachidonic acid may be important mediators in angiotensin II-induced vasoconstriction in the rat mesentery in vivo. Clin Sci (Lond) 98: 277-282, 2000.
6. Escalante B, Sessa WC, Falck JR, Yadagiri P, and Schwartzman ML. Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase. J Pharmacol Exp Ther 248: 229-232, 1988.
7. 2+ current. J Physiol 507: 771-781, 1998.
8. Harder DR, Gebremedhin D, Narayanan J, Jefcote C, Falck JR, Campbell WB, and Roman R. Formation and action of a P450 4A metabolite of arachidonic acid in cat cerebral microvessels. Am J Physiol Heart Circ Physiol 266: H2098-H2107, 1994.
9. Hill E, Fitzpatrick F, and Murphy RC. Biological activity and metabolism of 20-hydroxyeicosatetraenoic acid in the human platelet. Br J Pharmacol 106: 267-274, 1992.
10. Imig JD, Pham BT, LeBlanc EA, Reddy KM, Falck JR, and Inscho EW. Cytochrome P450 and cyclooxygenase metabolites contribute to the endothelin-1 afferent arteriolar vasoconstrictor and calcium responses. Hypertension 35: 307-312, 2000.
11. Imig JD, Zou AP, Ortiz-de-Montellano PR, Sui Z, and Roman RJ. Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure. Am J Physiol Heart Circ Physiol 266: H1879-H1885, 1994.
12. Imig JD, Zou AP, Stec DE, Harder DR, Falck JR, and Roman RJ. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am J Physiol Regul Integr Comp Physiol 270: R217-R227, 1996.
13. + channels in arteriolar muscle cells. Am J Physiol Heart Circ Physiol 274: H27-H34, 1998.
14. Kauser K, Clark JE, Masters BS, Ortiz de Montellano PR, Ma YH, Harder DR, and Roman RJ. Inhibitors of cytochrome P450 attenuate the myogenic response of dog renal arcuate arteries. Circ Res 68: 1154-1163, 1991.
15. Lange A, Gebremedhin D, Narayanan J, and Harder D. 20-Hydroxyeicosatetraenoic acid-induced vasoconstriction and inhibition of potassium current in cerebral vascular smooth muscle is dependent on activation of protein kinase C. J Biol Chem 272: 27345-27352, 1997.
16. Laniado-Schwartzman M, Falck JR, Yadagiri P, and Escalante B. Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase: Formation and identification of novel endothelium-dependent vasoconstrictor metabolites. J Biol Chem 264: 1165-1162, 1989.
17. Ma YH, Gebremedhin D, Schwartzman ML, Falck JR, Clark JE, Masters BSS, Harder DR, and Roman RJ. 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circ Res 72: 126-136, 1993.
18. Marji JS, Wang MH, and Laniado-Schwartzman M. Cytochrome P-450 4A isoform expression and 20-HETE synthesis in renal preglomerular arteries. Am J Physiol Renal Physiol 283: F60-F70, 2002.
19. Muthalif MM, Benter IF, Karzoun N, Fatima S, Harper J, Uddin MR, and Malik KU. 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. Proc Natl Acad Sci USA 95: 12701-12706, 1998.
20. Nguyen X, Wang MH, Reddy KM, Falck JR, and Schwartzman ML. Kinetic profile of the rat CYP4A isoforms: Arachidonic acid metabolism and isoform-specific inhibitors. Am J Physiol Regul Integr Comp Physiol 276: R1691-R1700, 1999.
21. +-ATPase. J Clin Invest 99: 1224-1230, 1997.
22. Oyekan AO and McGiff JC. Cytochrome P-450-derived eicosanoids participate in the renal functional effects of ET-1 in the anesthetized rat. Am J Physiol Regul Integr Comp Physiol 274: R52-R61, 1998.
23. + channel activity and vascular tone in renal arterioles. Circ Res 83: 1069-1079, 1998.
24. Sun CW, Falck JR, Harder DR, and Roman RJ. Role of tyrosine kinase and PKC in the vasoconstrictor response to 20-HETE in renal arterioles. Hypertension 33: 414-418, 1999.
25. Wang MH, Brand-Schieber E, Zand BA, Nguyen X, Falck JR, Balu N, and Laniado Schwartzman M. Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: Characterization of selective inhibitors. J Pharmacol Exp Ther 284: 966-973, 1998.
26. Wang MH, Guan H, Nguyen X, Zand B, Nasjletti A, and Laniado-Schwartzman M. Contribution of cytochrome P-450 4A1 and 4A2 to vascular 20-hydroxyeicosatetraenoic acid synthesis in the rat kidney. Am J Physiol Renal Physiol 276: F246-F253, 1999.
27. Zhang F, Wang MH, Krishna UM, Falck JR, Laniado-Schwartzman M, and Nasjletti A. Modulation by 20-HETE of phenylephrine-induced mesenteric artery contraction in spontaneously hypertensive and Wistar-Kyoto rats. Hypertension 38: 1311-1315, 2001.
28. + channel in renal arterioles. Am J Physiol Regul Integr Comp Physiol 270: R228-R237, 1996.
29. Zou AP, Imig JD, Kaldunski M, Ortiz de Montellano PR, Sui Z, and Roman RJ. Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. Am J Physiol Renal Fluid Electrolyte Physiol 266: F275-F282, 1994.