High salt intake reduces endothelium-dependent dilation of mouse arterioles via superoxide anion generated from nitric oxide synthase

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 4, 2007, Pages

  Nurkiewicz, Timothy R ^a   Boegehold, Matthew A ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Microcirculation; NOS uncoupling; Reactive oxygen species

Indexed keywords

ACETYLCHOLINE; CATALASE; HYDROETHIDINE; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE; PIPERIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TETRAZOLIUM BLUE;

ANIMAL EXPERIMENT; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTERY WALL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDING; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MOUSE; MUSCLE BLOOD FLOW; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SALT INTAKE; SKELETAL MUSCLE;

ACETYLCHOLINE; ANIMALS; ANTIOXIDANTS; ARTERIOLES; BIOLOGICAL AVAILABILITY; CATALASE; CYCLIC N-OXIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; SODIUM CHLORIDE, DIETARY; SUPEROXIDES; VASODILATION; VASODILATOR AGENTS;

EID: 34147172151     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00703.2006     Document Type: Article

References (49)

1. Ahn D, Ge Y, Stricklett PK, Gill P, Taylor D, Hughes AK, Yanagisawa M, Miller L, Nelson RD, Kohan DE. Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention. J Clin Invest 114: 504-511, 2004.
2. 2 receptors. Hypertension 29: 483-487, 1997.
3. Bagi Z, Koller A. Lack of nitric oxide mediation of flow-dependent arteriolar dilation in Type 1 diabetes is restored by sepiapterin. J Vasc Res 40: 47-57, 2003.
4. Bearden SE, Segal SS. Neurovascular alignment in adult mouse skeletal muscles. Microcirculation 12:161-167, 2005.
5. Benov L, Sztejnberg L, Fridovich I. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radic Biol Med 25: 826-831, 1998.
6. Bindokas VP, Jordan J, Lee CC, Miller RJ. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 16: 1324-1326, 1989.
7. Boegehold MA. Effect of dietary salt on arteriolar nitric oxide in striated muscle of normotensive rats. Am J Physiol Heart Circ Physiol 264: H1810-H1816, 1993.
8. Boegehold MA. Flow-dependent arteriolar dilation in normotensive rats fed low- or high-salt diets. Am J Physiol Heart Circ Physiol 269: H1407-H1414, 1995.
9. Boegehold MA, Bohlen HG. Arteriolar diameter and tissue oxygen tension during muscle contraction in hypertensive rats. Hypertension 12: 184-191, 1988.
10. Carlson SH, Oparil S, Chen YF, Wyss JM. Blood pressure and NaCl-sensitive hypertension are influenced by angiotensin-converting enzyme gene expression in transgenic mice. Hypertension 39: 214-218, 2002.
11. Cosentino F, Barker JE, Brand MP, Heales SJ, Werner ER, Tippins JR, West N, Channon KM, Volpe M, Luscher TF. Reactive oxygen species mediate endothelium-dependent relaxations in tetrahydrobiopterin-deficient mice. Arterioscler Thromb Vasc Biol 21: 496-502, 2001.
12. de Wit C, von Bismarck P, Pohl U. Mediator role of prostaglandins in acetylcholine-induced vasodilation and control of resting vascular diameter in the hamster cremaster microcirculation in vivo. J Vasc Res 30: 272-278, 1993.
13. Fang Q, Sun H, Mayhan WG. Impairment of nitric oxide synthase-dependent dilatation of cerebral arterioles during infusion of nicotine. Am J Physiol Heart Circ Physiol 284: H528-H534, 2003.
14. Fleming I, Michaelis UR, Bredenkotter D, Fisslthaler B, Dehghani F, Brandes RP, Busse R. Endothelium-derived hyperpolarizing factor synthase (cytochrome P-450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circ Res 88: 44-51, 2001.
15. Fuchs J, Groth N, Herrling T, Zimmer G. Electron paramagnetic resonance studies on nitroxide radical 2,2,5,5- tetramethyl-4-piperidin-1-oxyl (TEMPO) redox reactions in human skin. Free Radic Biol Med 22: 967-976, 1997.
16. Gorren AC, Schrammel A, Schmidt K, Mayer B. Effects of pH on the structure and function of neuronal nitric oxide synthase. Biochem J 331: 801-807, 1998.
17. Govers R, Rabelink TJ. Cellular regulation of endothelial nitric oxide synthase. Am J Physiol Renal Physiol 280: F193-F206, 2001.
18. Hansen-Smith FM, Morris LW, Greene AS, Lombard JH. Rapid microvessel rarefaction with elevated salt intake and reduced renal mass hypertension in rats. Circ Res 79: 324-330, 1996.
19. Holland JA, Pritchard KA, Pappolla MA, Wolin MS, Rogers NJ, Stemerman MB. Bradykinin induces superoxide anion release from human endothelial cells. J Cell Physiol 143: 21-25, 1990.
20. Hong HJ, Hsiao G, Cheng TH, Yen MH. Supplementation with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats. Hypertension 38: 1044-1048, 2001.
21. Huang A, Sun D, Smith CJ, Connetta JA, Shesely EG, Koller A, Kaley G. In eNOS knockout mice skeletal muscle arteriolar dilation to acetylcholine is mediated by EDHF. Am J Physiol Heart Circ Physiol 278: H762-H768, 2000.
22. Jiang J, Valen G, Tokuno S, Thoren P, Pernow J. Endothelial dysfunction in atherosclerotic mice: Improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin. Br J Pharmacol 131: 1255-1261, 2000.
23. Kitiyakara C, Chabrashvili T, Jose P, Welch WJ, Wilcox CS. Effects of dietary salt intake on plasma arginine. Am J Physiol Regul Integr Comp Physiol 280: R1069-R1075, 2001.
24. Kotchen TA. To salt, or not to salt? Am J Physiol Heart Circ Physiol 276: H1807-H1810, 1999.
25. Lavoie JL, Bianco RA, Sakai K, Keen HL, Ryan MJ, Sigmund CD. Transgenic mice for studies of the renin-angiotensin system in hypertension. Acta Physiol Scand 181:571-577, 2004.
26. Lee RM, Triggle CR. Morphometric study of mesenteric arteries from genetically hypertensive Dahl strain rats. Blood Vessels 23: 199-224, 1986.
27. Lenda DM, Boegehold MA. Effect of a high salt diet on microvascular antioxidant enzymes. J Vasc Res 39: 41-50, 2002.
28. Lenda DM, Boegehold MA. Effect of a high salt diet on oxidant enzyme activity in skeletal muscle microcirculation. Am J Physiol Heart Circ Physiol 282: H395-H402, 2002.
29. Lenda DM, Sauls BA, Boegehold MA. Reactive oxygen species may contribute to reduced endothelium-dependent dilation in rats fed high salt. Am J Physiol Heart Circ Physiol 279: H7-H14, 2000.
30. Linderman JR, Boegehold MA. Growth-related changes in the influence of nitric oxide on arteriolar tone. Am J Physiol Heart Circ Physiol 277: H1570-H1578, 1999.
31. 1A receptor deletion on blood pressure and sodium excretion during altered dietary salt intake. Am J Physiol Renal Physiol 283: F447-F453, 2002.
32. Marvar PJ, Boegehold MA. Reduced arteriolar responses to skeletal muscle contraction after ingestion of a high-salt diet. J Vasc Res 42: 226-236, 2005.
33. Matsuoka H, Itoh S, Kimoto M, Kohno K, Tamai O, Wada Y, Yasukawa H, Iwami G, Okuda S, Imaizumi T. Asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in experimental hypertension. Hypertension 29: 242-247, 1997.
34. Morgan AR, Evans DH, Lee JS, Pulleyblank DE. Review: ethidium fluorescence assay. Part II Enzymatic studies and DNA-protein interactions. Nucleic Acids Res 7: 571-594, 1979.
35. G-monomethyl L-arginine on endothelium-dependent relaxation in arterioles of one-kidney, one clip hypertensive rats. Hypertension 17: 875-880, 1991.
36. Nurkiewicz TR, Boegehold MA. High dietary salt alters arteriolar myogenic responsiveness in normotensive and hypertensive rats. Am J Physiol Heart Circ Physiol 275: H2095-H2104, 1998.
37. Nurkiewicz TR, Boegehold MA. Limitation of arteriolar myogenic activity by local nitric oxide: segment-specific effect of dietary salt. Am J Physiol Heart Circ Physiol 277: H1946-H1955, 1999.
38. Nurkiewicz TR, Boegehold MA. Reinforcement of arteriolar myogenic activity by endogenous ANG II: susceptibility to dietary salt. Am J Physiol Heart Circ Physiol 279: H269-H278, 2000.
39. Oritz PA, Garvin JL. Cardiovascular and renal control in NOS-deficient mouse models. Am J Physiol Regul Integr Comp Physiol 284: R628-R638, 2003.
40. Persson MG, Gustafsson LE, Wiklund NP, Hedquist P, Moncada S. Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo. Br J Pharmacol 100: 463-466, 1990.
41. Scuteri A, Stuehlinger MC, Cooke JP, Wright JG, Lakatta EG, Anderson DE, Fleg JL. Nitric oxide inhibition as a mechanism for blood pressure increase during salt loading in normotensive postmenopausal women. J Hypertens 21: 1339-1346, 2003.
42. Sun H, Patel KP, Mayhan WG. Tetrahydrobiopterin, a cofactor of NOS, improves endothelial dysfunction during chronic alcohol consumption. Am J Physiol Heart Circ Physiol 281: H1863-H1869, 2001.
43. Suzuki H, Swei A, Zweifach BW, and Schmid-Schönbein GW. In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats Hydroethidine microfluorography. Hypertension 25: 1083-1089, 1995.
44. Sydow K, Munzel T. ADMA and oxidative stress. Atherosclerosis Suppl 4: 41-51, 2003.
45. Sylvester FA, Stepp DW, Frisbee JC, Lombard JH. High-salt diet depresses acetylcholine reactivity proximal to NOS activation in cerebral arteries. Am J Physiol Heart Circ Physiol 283: H353-H363, 2002.
46. Vasquez-Vivar J, Kalyanaraman B, Martasek P, Hogg N, Masters BS, Karoui H, Tordo P, Pritchard KA. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA 95: 9220-9225, 1998.
47. Wood PA, Hamm DA, Chen PY, Sanders PW. Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension. Mol Genet Metab 64: 80-83, 1998.
48. Zhu J, Mori T, Huang T, Lombard JH. Effect of high-salt diet on NO release and superoxide production in rat aorta. Am J Physiol Heart Circ Physiol 286: H575-H583, 2004.
49. Zou MH, Shi C, Cohen RA. Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest 109: 817-826, 2002.