-
1
-
-
0014941813
-
A theory of self-nonself discrimination
-
1 Bretscher P, Cohn M. A theory of self-nonself discrimination. Science 1970; 169: 1042-9.
-
(1970)
Science
, vol.169
, pp. 1042-1049
-
-
Bretscher, P.1
Cohn, M.2
-
2
-
-
0025339511
-
A cell culture model for T lymphocyte clonal anergy
-
2 Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990; 248: 1349-56.
-
(1990)
Science
, vol.248
, pp. 1349-1356
-
-
Schwartz, R.H.1
-
3
-
-
0026541544
-
The two-signal model of lymphocyte activation twenty-one years later
-
3 Bretscher P. The two-signal model of lymphocyte activation twenty-one years later. Immunol. Today 1992; 13: 74-6.
-
(1992)
Immunol. Today
, vol.13
, pp. 74-76
-
-
Bretscher, P.1
-
5
-
-
0021840708
-
Human T cell activation II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen)
-
5 Hara T, Fu SM, Hansen JA. Human T cell activation II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J. Exp. Med. 1985; 161: 1513-24.
-
(1985)
J. Exp. Med.
, vol.161
, pp. 1513-1524
-
-
Hara, T.1
Fu, S.M.2
Hansen, J.A.3
-
6
-
-
0022632220
-
A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes
-
6 Martin PJ, Ledbetter JA, Morishita Y, June CH, Beatty CH, Hansen JA. A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes. J. Immunol. 1986; 136: 3282-7.
-
(1986)
J. Immunol.
, vol.136
, pp. 3282-3287
-
-
Martin, P.J.1
Ledbetter, J.A.2
Morishita, Y.3
June, C.H.4
Beatty, C.H.5
Hansen, J.A.6
-
7
-
-
0023929216
-
Differential regulatory signals delivered by antibody binding to the CD28 (Tp44) molecule during the activation of human T lymphocytes
-
7 Damle NK, Doyle LV, Grosmaire LS, Ledbetter JA. Differential regulatory signals delivered by antibody binding to the CD28 (Tp44) molecule during the activation of human T lymphocytes. J. Immunol. 1988; 140: 1753-61.
-
(1988)
J. Immunol.
, vol.140
, pp. 1753-1761
-
-
Damle, N.K.1
Doyle, L.V.2
Grosmaire, L.S.3
Ledbetter, J.A.4
-
8
-
-
0024506159
-
Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
-
8 Lindsten T, June CM, Ledbetter JA, Stella G, Thompson CB. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 1989; 244: 339-43.
-
(1989)
Science
, vol.244
, pp. 339-343
-
-
Lindsten, T.1
June, C.M.2
Ledbetter, J.A.3
Stella, G.4
Thompson, C.B.5
-
9
-
-
0025234426
-
CD28 ligation in T-cell activation: Evidence for two signal transduction pathways
-
9 Ledbetter JA, Imboden JB, Schieven GL et al. CD28 ligation in T-cell activation: Evidence for two signal transduction pathways. Blood 1990; 75: 1531-9.
-
(1990)
Blood
, vol.75
, pp. 1531-1539
-
-
Ledbetter, J.A.1
Imboden, J.B.2
Schieven, G.L.3
-
10
-
-
0025833603
-
T cell receptor/CD3 and CD28 use distinct intracellular signaling pathways
-
10 Van Lier RA, Brouwer M, De Groot ED, Kramer I, Aarden LA, Verhoeven AJ. T cell receptor/CD3 and CD28 use distinct intracellular signaling pathways. Eur. J. Immunol. 1991; 21: 1775-8.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 1775-1778
-
-
Van Lier, R.A.1
Brouwer, M.2
De Groot, E.D.3
Kramer, I.4
Aarden, L.A.5
Verhoeven, A.J.6
-
12
-
-
0025947895
-
CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells
-
12 Jenkins MK, Taylor PS, Norton SD, Urdahl KB. CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. J. Immunol. 1991; 147: 2461-6.
-
(1991)
J. Immunol.
, vol.147
, pp. 2461-2466
-
-
Jenkins, M.K.1
Taylor, P.S.2
Norton, S.D.3
Urdahl, K.B.4
-
13
-
-
0027403299
-
The role of the CD28 receptor during T cell responses to antigen
-
13 Linsley PS, Ledbetter JA. The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 1993; 11: 191-212.
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 191-212
-
-
Linsley, P.S.1
Ledbetter, J.A.2
-
14
-
-
0025963594
-
Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
-
14 Linsley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J. Exp. Med. 1991; 173: 721-30.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 721-730
-
-
Linsley, P.S.1
Brady, W.2
Grosmaire, L.3
Aruffo, A.4
Damle, N.K.5
Ledbetter, J.A.6
-
15
-
-
0023270567
-
A new member of the immunoglobulin superfamily: CTLA-4
-
15 Brunet JF, Denizot F, Luciani MF et al. A new member of the immunoglobulin superfamily: CTLA-4. Nature 1987; 328: 267-70.
-
(1987)
Nature
, vol.328
, pp. 267-270
-
-
Brunet, J.F.1
Denizot, F.2
Luciani, M.F.3
-
16
-
-
0025735829
-
CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location
-
16 Harper K, Balzano C, Rouvier E, Mattei MG, Luciani MF, Golstein P. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J. Immunol. 1991; 147: 1037-44.
-
(1991)
J. Immunol.
, vol.147
, pp. 1037-1044
-
-
Harper, K.1
Balzano, C.2
Rouvier, E.3
Mattei, M.G.4
Luciani, M.F.5
Golstein, P.6
-
17
-
-
0025979295
-
CD28 and CTLA-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome I
-
17 Howard TA, Rochelle JM, Seldin MF. CD28 and CTLA-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome I. Immunogenetics 1991; 33: 74-6.
-
(1991)
Immunogenetics
, vol.33
, pp. 74-76
-
-
Howard, T.A.1
Rochelle, J.M.2
Seldin, M.F.3
-
18
-
-
0025217670
-
Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34
-
18 Lafage-Pochitaloff M, Costello R, Couez D et al. Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34. Immunogenetics 1990; 31: 198-201.
-
(1990)
Immunogenetics
, vol.31
, pp. 198-201
-
-
Lafage-Pochitaloff, M.1
Costello, R.2
Couez, D.3
-
19
-
-
0026477970
-
CTLA-4 and CD28: Similar proteins, neighbouring genes
-
19 Balzano C, Buonavista N, Rouvier E, Golstein P. CTLA-4 and CD28: Similar proteins, neighbouring genes. Int. J. Cancer 1992; 7: 28-32.
-
(1992)
Int. J. Cancer
, vol.7
, pp. 28-32
-
-
Balzano, C.1
Buonavista, N.2
Rouvier, E.3
Golstein, P.4
-
20
-
-
0029097387
-
Activated T cells can induce high levels of CTLA-4 expression on B cells
-
20 Kuiper HM, Brouwer M, Linsley PS, van Lier RA. Activated T cells can induce high levels of CTLA-4 expression on B cells. J. Immunol. 1995; 155: 1776-83.
-
(1995)
J. Immunol.
, vol.155
, pp. 1776-1783
-
-
Kuiper, H.M.1
Brouwer, M.2
Linsley, P.S.3
Van Lier, R.A.4
-
21
-
-
10544242196
-
Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2
-
21 Wagner DH, Hagman J, Linsley PS, Hodsdon W, Freed JH, Newell MK. Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2. J. Exp. Med. 1996; 184: 1631-8.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1631-1638
-
-
Wagner, D.H.1
Hagman, J.2
Linsley, P.S.3
Hodsdon, W.4
Freed, J.H.5
Newell, M.K.6
-
22
-
-
0026486220
-
Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes
-
22 Linsley PS, Greene JL, Tan P et al. Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes. J. Exp. Med. 1992; 176: 1595-604.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1595-1604
-
-
Linsley, P.S.1
Greene, J.L.2
Tan, P.3
-
23
-
-
0027282960
-
Characterization of CTLA-4 structure and expression on human T cells
-
23 Lindsten T, Lee KP, Harris ES et al. Characterization of CTLA-4 structure and expression on human T cells. J. Immunol. 1993; 151: 3489-99.
-
(1993)
J. Immunol.
, vol.151
, pp. 3489-3499
-
-
Lindsten, T.1
Lee, K.P.2
Harris, E.S.3
-
24
-
-
0028484545
-
CTLA-4 can function as a negative regulator of T cell activation
-
24 Walunas TL, Lenschow DJ, Bakker CY et al. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994; 1: 405-13.
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
-
25
-
-
0024205313
-
Human Ig superfamily CTLA-4 gene: Chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains
-
25 Dariavach P, Mattei MG, Golstein P, Lefranc MP. Human Ig superfamily CTLA-4 gene: Chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. Eur. J. Immunol. 1988; 18: 1901-5.
-
(1988)
Eur. J. Immunol.
, vol.18
, pp. 1901-1905
-
-
Dariavach, P.1
Mattei, M.G.2
Golstein, P.3
Lefranc, M.P.4
-
26
-
-
0027057908
-
CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production
-
26 Freeman GJ, Lombard DB, Gimmi CD et al. CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production. J. Immunol. 1992; 149: 3795-801.
-
(1992)
J. Immunol.
, vol.149
, pp. 3795-3801
-
-
Freeman, G.J.1
Lombard, D.B.2
Gimmi, C.D.3
-
27
-
-
0030176371
-
Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
-
27 Linsley PS, Bradshaw J, Greene J, Peach R, Bennett KL, Mittler RS. Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement. Immunity 1996; 4: 535-43.
-
(1996)
Immunity
, vol.4
, pp. 535-543
-
-
Linsley, P.S.1
Bradshaw, J.2
Greene, J.3
Peach, R.4
Bennett, K.L.5
Mittler, R.S.6
-
28
-
-
0031181647
-
Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression
-
28 Chuang E., Alegre M-L, Duckett CS, Noel PJ, Vander Heiden MG, Thompson CB. Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression. J. Immunol. 1997; 159: 144-51.
-
(1997)
J. Immunol.
, vol.159
, pp. 144-151
-
-
Chuang, E.1
Alegre, M.-L.2
Duckett, C.S.3
Noel, P.J.4
Vander Heiden, M.G.5
Thompson, C.B.6
-
29
-
-
0030917081
-
Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2
-
29 Shiratori T, Miyatake S, Ohno H et al. Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. Immunity 1997; 6: 583-9.
-
(1997)
Immunity
, vol.6
, pp. 583-589
-
-
Shiratori, T.1
Miyatake, S.2
Ohno, H.3
-
30
-
-
0025830902
-
CTLA-4 is a second receptor for the B cell activation antigen B7
-
30 Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA. CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp. Med. 1991; 174: 561-9.
-
(1991)
J. Exp. Med.
, vol.174
, pp. 561-569
-
-
Linsley, P.S.1
Brady, W.2
Urnes, M.3
Grosmaire, L.S.4
Damle, N.K.5
Ledbetter, J.A.6
-
31
-
-
0027729845
-
Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice
-
31 Freeman GJ, Borriello F, Hodes RJ et al. Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 1993; 262: 907-9.
-
(1993)
Science
, vol.262
, pp. 907-909
-
-
Freeman, G.J.1
Borriello, F.2
Hodes, R.J.3
-
32
-
-
0027362823
-
B70 antigen is a second ligand for CTLA-4 and CD28
-
32 Azuma M, Ito D, Yagita H et al. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 1993; 366: 76-9.
-
(1993)
Nature
, vol.366
, pp. 76-79
-
-
Azuma, M.1
Ito, D.2
Yagita, H.3
-
33
-
-
0027937702
-
Complementarity determining region 1 (CDR1)-and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1
-
33 Peach RJ, Bajorath J, Brady W et al. Complementarity determining region 1 (CDR1)-and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. J. Exp. Med. 1994; 180: 2049-58.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2049-2058
-
-
Peach, R.J.1
Bajorath, J.2
Brady, W.3
-
34
-
-
0028215960
-
Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7
-
34 Damle NK, Klussman K, Leytze G et al. Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7. J. Immunol. 1994; 152: 2686-97.
-
(1994)
J. Immunol.
, vol.152
, pp. 2686-2697
-
-
Damle, N.K.1
Klussman, K.2
Leytze, G.3
-
35
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
35 Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 1995; 182: 459-65.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
36
-
-
0029117327
-
Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation
-
36 Linsley PS. Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation. J. Exp. Med. 1995; 182: 289-92.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 289-292
-
-
Linsley, P.S.1
-
37
-
-
0030902622
-
CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion
-
37 Wu Y, Guo Y, Huang A, Zheng P, Liu Y. CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion. J. Exp. Med. 1997; 185: 1327-35.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1327-1335
-
-
Wu, Y.1
Guo, Y.2
Huang, A.3
Zheng, P.4
Liu, Y.5
-
38
-
-
0028675006
-
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
-
38 Linsley PS, Greene JL, Brady W, Bajorath J, Ledbetter JA, Peach R. Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity 1994; 1: 793-801.
-
(1994)
Immunity
, vol.1
, pp. 793-801
-
-
Linsley, P.S.1
Greene, J.L.2
Brady, W.3
Bajorath, J.4
Ledbetter, J.A.5
Peach, R.6
-
39
-
-
0345368071
-
Is CTLA-4 a negative regulator for T-cell activation?
-
39 Liu Y. Is CTLA-4 a negative regulator for T-cell activation? Immunol. Today 1997; 18: 569-72.
-
(1997)
Immunol. Today
, vol.18
, pp. 569-572
-
-
Liu, Y.1
-
41
-
-
0029953858
-
CTLA-4 ligation blocks CD28-dependent T cell activation
-
41 Walunas TL, Bakker CY, Bluestone JA. CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 1996; 183: 2541-50.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2541-2550
-
-
Walunas, T.L.1
Bakker, C.Y.2
Bluestone, J.A.3
-
42
-
-
0029899783
-
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
-
42 Krummel MF, Allison JP. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 1996; 183: 2533-40.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2533-2540
-
-
Krummel, M.F.1
Allison, J.P.2
-
43
-
-
0028841784
-
The yin and yang of T cell costimulation
-
43 Allison JP, Krummel MF. The yin and yang of T cell costimulation. Science 1995; 270: 932-3.
-
(1995)
Science
, vol.270
, pp. 932-933
-
-
Allison, J.P.1
Krummel, M.F.2
-
44
-
-
0029100024
-
Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4
-
44 Kearney ER, Walunas TL, Karr RW et al. Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. J. Immunol. 1995; 155: 1032-6.
-
(1995)
J. Immunol.
, vol.155
, pp. 1032-1036
-
-
Kearney, E.R.1
Walunas, T.L.2
Karr, R.W.3
-
45
-
-
0029960141
-
Superantigen responses and co-stimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo
-
45 Krummel MF, Sullivan TJ, Allison JP. Superantigen responses and co-stimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo. Int. Immunol. 1996; 8: 519-23.
-
(1996)
Int. Immunol.
, vol.8
, pp. 519-523
-
-
Krummel, M.F.1
Sullivan, T.J.2
Allison, J.P.3
-
46
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
46 Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996; 271: 1734-6.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
47
-
-
0030872154
-
Protective immunity to nematode infection is induced by CTLA-4 blockade
-
47 McCoy KD, Camberis M, Le Gros G. Protective immunity to nematode infection is induced by CTLA-4 blockade. J. Exp. Med. 1997; 186: 183-7.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 183-187
-
-
McCoy, K.D.1
Camberis, M.2
Le Gros, G.3
-
48
-
-
0032490620
-
Cytotoxic T lymphocyte antigen 4 (CTLA-4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA-4 can function independently of CD28
-
48 Lin H, Rathmell JC, Gray GS, Thompson CB, Leiden JM, Alegre ML. Cytotoxic T lymphocyte antigen 4 (CTLA-4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA-4 can function independently of CD28. J. Exp. Med. 1998; 188: 199-204.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 199-204
-
-
Lin, H.1
Rathmell, J.C.2
Gray, G.S.3
Thompson, C.B.4
Leiden, J.M.5
Alegre, M.L.6
-
49
-
-
0032490629
-
B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28
-
49 Fallarino F, Fields PE, Gajewski TF. B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28. J. Exp. Med. 1998; 188: 205-10.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 205-210
-
-
Fallarino, F.1
Fields, P.E.2
Gajewski, T.F.3
-
50
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
50 Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995; 3: 541-7.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
51
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
51 Waterhouse P, Penninger JM, Timms E et al. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 1995; 270: 985-8.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
52
-
-
0031154577
-
CTLA-4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
-
52 Tivol EA, Boyd SD, McKeon S et al. CTLA-4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J. Immunol. 1997; 158: 5091-4.
-
(1997)
J. Immunol.
, vol.158
, pp. 5091-5094
-
-
Tivol, E.A.1
Boyd, S.D.2
McKeon, S.3
-
53
-
-
0031405867
-
Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells
-
53 Chambers CA, Sullivan TJ, Allison JP. Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells. Immunity 1997; 7: 885-95.
-
(1997)
Immunity
, vol.7
, pp. 885-895
-
-
Chambers, C.A.1
Sullivan, T.J.2
Allison, J.P.3
-
54
-
-
0028927607
-
The Fas death factor
-
54 Nagata S, Golstein P. The Fas death factor. Science 1995; 267: 1449-56.
-
(1995)
Science
, vol.267
, pp. 1449-1456
-
-
Nagata, S.1
Golstein, P.2
-
55
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
55 Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267: 1456-62.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
56
-
-
0030113898
-
Lymphocyte activation: T-cell regulation by CTLA-4
-
56 Linsley PS, Golstein P. Lymphocyte activation: T-cell regulation by CTLA-4. Curr. Biol. 1996; 6: 398-400.
-
(1996)
Curr. Biol.
, vol.6
, pp. 398-400
-
-
Linsley, P.S.1
Golstein, P.2
-
57
-
-
0030740572
-
Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice
-
57 Waterhouse P, Bachmann MF, Penninger JM, Ohashi PS, Mak TW. Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice. Eur. J. Immunol. 1997; 27: 1887-92.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 1887-1892
-
-
Waterhouse, P.1
Bachmann, M.F.2
Penninger, J.M.3
Ohashi, P.S.4
Mak, T.W.5
-
59
-
-
0030300146
-
CTLA-4, a negative regulator of T-lymphocyte activation
-
59 Waterhouse P, Marengere LE, Mittrucker HW, Mak TW. CTLA-4, a negative regulator of T-lymphocyte activation. Immunol. Rev. 1996; 153: 183-207.
-
(1996)
Immunol. Rev.
, vol.153
, pp. 183-207
-
-
Waterhouse, P.1
Marengere, L.E.2
Mittrucker, H.W.3
Mak, T.W.4
-
60
-
-
0032547259
-
Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152)
-
60 Miyatake S, Nakaseko C, Umemori H, Yamamoto T, Saito T. Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152). Biochem. Biophys. Res. Commun. 1998; 249: 444-8.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.249
, pp. 444-448
-
-
Miyatake, S.1
Nakaseko, C.2
Umemori, H.3
Yamamoto, T.4
Saito, T.5
-
61
-
-
0028211126
-
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3′-kinase
-
61 Stein PH, Fraser JD, Weiss A. The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3′-kinase. Mol. Cell. Biol. 1994; 14: 3392-402.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3392-3402
-
-
Stein, P.H.1
Fraser, J.D.2
Weiss, A.3
-
62
-
-
0028910221
-
CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells
-
62 Schneider H, Prasad KV, Shoelson SE, Rudd CE. CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells. J. Exp. Med. 1995; 181: 351-5.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 351-355
-
-
Schneider, H.1
Prasad, K.V.2
Shoelson, S.E.3
Rudd, C.E.4
-
63
-
-
0030707866
-
Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70
-
63 Calvo CR, Amsen D, Kruisbeek AM. Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70. J. Exp. Med. 1997; 186: 1645-53.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1645-1653
-
-
Calvo, C.R.1
Amsen, D.2
Kruisbeek, A.M.3
-
65
-
-
0030001318
-
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
-
65 Marengere LE, Waterhouse P, Duncan GS, Mittrucker HW, Feng GS, Mak TW. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 1996; 272: 1170-3.
-
(1996)
Science
, vol.272
, pp. 1170-1173
-
-
Marengere, L.E.1
Waterhouse, P.2
Duncan, G.S.3
Mittrucker, H.W.4
Feng, G.S.5
Mak, T.W.6
-
66
-
-
0028852073
-
Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail
-
66 Leung HT, Bradshaw J, Cleaveland JS, Linsley PS. Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail. J. Biol. Chem. 1995; 270: 25 107-14.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25107-25114
-
-
Leung, H.T.1
Bradshaw, J.2
Cleaveland, J.S.3
Linsley, P.S.4
-
67
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
-
67 Kuchroo VK, Das MP, Brown JA et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy. Cell 1995; 80: 707-18.
-
(1995)
Cell
, vol.80
, pp. 707-718
-
-
Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
-
68
-
-
0029553431
-
Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE
-
68 Miller SD, Vanderlugt CL, Lenschow DJ et al. Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE. Immunity 1995; 3: 739-45.
-
(1995)
Immunity
, vol.3
, pp. 739-745
-
-
Miller, S.D.1
Vanderlugt, C.L.2
Lenschow, D.J.3
-
70
-
-
0029789389
-
CTLA-4: A negative regulator of autoimmune disease
-
70 Karandikar NJ, Vanderlugt CL, Walunas TL, Miller SD, Bluestone JA. CTLA-4: A negative regulator of autoimmune disease. J. Exp. Med. 1996; 184: 783-8.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 783-788
-
-
Karandikar, N.J.1
Vanderlugt, C.L.2
Walunas, T.L.3
Miller, S.D.4
Bluestone, J.A.5
-
71
-
-
0030586626
-
CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis
-
71 Perrin PJ, Maldonado JH, Davis TA, June CH, Racke MK. CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis. J. Immunol. 1996; 157: 1333-6.
-
(1996)
J. Immunol.
, vol.157
, pp. 1333-1336
-
-
Perrin, P.J.1
Maldonado, J.H.2
Davis, T.A.3
June, C.H.4
Racke, M.K.5
-
72
-
-
2642655282
-
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
-
72 Lühder F, Höglund P, Allison JP, Benoist C, Mathis D. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. J. Exp. Med. 1998; 187: 427-32.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 427-432
-
-
Lühder, F.1
Höglund, P.2
Allison, J.P.3
Benoist, C.4
Mathis, D.5
-
73
-
-
0027299866
-
Homing of naive, memory and effector lymphocytes
-
73 MacKay CR. Homing of naive, memory and effector lymphocytes. Curr: Opin. Immunol. 1993; 5: 423-7.
-
(1993)
Curr: Opin. Immunol.
, vol.5
, pp. 423-427
-
-
MacKay, C.R.1
-
74
-
-
8944259914
-
The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes
-
74 Nistico L, Buzzetti R, Pritchard LE et al. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum. Mol. Genet. 1996; 5: 1075-80.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1075-1080
-
-
Nistico, L.1
Buzzetti, R.2
Pritchard, L.E.3
-
75
-
-
0029837733
-
Panning for gold: Genome-wide scanning for linkage in type 1 diabetes
-
75 Todd JA, Farrall M. Panning for gold: Genome-wide scanning for linkage in type 1 diabetes. Hum. Mol. Genet. 1996; 5: 1443-8.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1443-1448
-
-
Todd, J.A.1
Farrall, M.2
-
76
-
-
0031975367
-
Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's thyroiditis) in the Japanese population
-
76 Awata T, Kurihara S, Iitaka M et al. Association of CTLA-4 gene A-G polymorphism (IDDM12 locus) with acute-onset and insulin-depleted IDDM as well as autoimmune thyroid disease (Graves' disease and Hashimoto's thyroiditis) in the Japanese population. Diabetes 1998; 47: 128-9.
-
(1998)
Diabetes
, vol.47
, pp. 128-129
-
-
Awata, T.1
Kurihara, S.2
Iitaka, M.3
-
77
-
-
8544274482
-
Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups
-
77 Marron MP, Raffel LJ, Garchon HJ et al. Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups. Hum. Mol. Genet. 1997; 6: 1275-82.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 1275-1282
-
-
Marron, M.P.1
Raffel, L.J.2
Garchon, H.J.3
-
78
-
-
0031810837
-
CTLA-4 gene polymorphism is associated with predisposition to IDDM in a population from central Poland
-
78 Krokowski M, Bodalski J, Bratek A, Machejko P, Caillat-Zucman S. CTLA-4 gene polymorphism is associated with predisposition to IDDM in a population from central Poland. Diabete Metab. 1998; 24: 241-3.
-
(1998)
Diabete Metab.
, vol.24
, pp. 241-243
-
-
Krokowski, M.1
Bodalski, J.2
Bratek, A.3
Machejko, P.4
Caillat-Zucman, S.5
-
79
-
-
9844263372
-
CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers
-
79 Van der Auwera BJ, Vandewalle CL, Schuit FC et al. CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. Clin. Exp. Immunol. 1997; 110: 98-103.
-
(1997)
Clin. Exp. Immunol.
, vol.110
, pp. 98-103
-
-
Van Der Auwera, B.J.1
Vandewalle, C.L.2
Schuit, F.C.3
-
80
-
-
0031014716
-
CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type I diabetes mellitus
-
80 Donner H, Rau H, Walfish PG et al. CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type I diabetes mellitus. J. Clin. Endocrinol. Metab. 1997; 82: 143-6.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 143-146
-
-
Donner, H.1
Rau, H.2
Walfish, P.G.3
-
81
-
-
0031434409
-
CTLA4 gene polymorphism confers susceptibility to Graves' disease in Japanese
-
81 Yanagawa T, Taniyama M, Enomoto S et al. CTLA4 gene polymorphism confers susceptibility to Graves' disease in Japanese. Thyroid 1997; 7: 843-6.
-
(1997)
Thyroid
, vol.7
, pp. 843-846
-
-
Yanagawa, T.1
Taniyama, M.2
Enomoto, S.3
-
82
-
-
0030816688
-
A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism
-
82 Kotsa K, Watson PF, Weetman AP. A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism. Clin. Endocrinol. 1997; 46: 551-4.
-
(1997)
Clin. Endocrinol.
, vol.46
, pp. 551-554
-
-
Kotsa, K.1
Watson, P.F.2
Weetman, A.P.3
-
83
-
-
0030966217
-
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement
-
83 Perez VL, Van Parijs L, Biuckians A, Zheng XX, Strom TB, Abbas AK. Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity 1997; 6: 411-17.
-
(1997)
Immunity
, vol.6
, pp. 411-417
-
-
Perez, V.L.1
Van Parijs, L.2
Biuckians, A.3
Zheng, X.X.4
Strom, T.B.5
Abbas, A.K.6
-
85
-
-
0030927323
-
Making the T cell receptor go the distance: A topological view of T cell activation
-
85 Shaw AS, Dustin ML. Making the T cell receptor go the distance: A topological view of T cell activation. Immunity 1997; 6: 361-9.
-
(1997)
Immunity
, vol.6
, pp. 361-369
-
-
Shaw, A.S.1
Dustin, M.L.2
-
86
-
-
0028178873
-
Signals and signs for lymphocyte responses
-
86 Janeway Jr CA, Bottomly K. Signals and signs for lymphocyte responses. Cell 1994; 76: 275-85.
-
(1994)
Cell
, vol.76
, pp. 275-285
-
-
Janeway C.A., Jr.1
Bottomly, K.2
-
88
-
-
0030300139
-
The role of CTLA-4 in the regulation and initiation of T-cell responses
-
88 Chambers CA, Krummel MF, Boitel B et al. The role of CTLA-4 in the regulation and initiation of T-cell responses. Immunol. Rev. 1996; 153: 27-46.
-
(1996)
Immunol. Rev.
, vol.153
, pp. 27-46
-
-
Chambers, C.A.1
Krummel, M.F.2
Boitel, B.3
-
89
-
-
0031091743
-
Is CTLA-4 a master switch for peripheral T cell tolerance?
-
89 Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J. Immunol. 1997; 158: 1989-93.
-
(1997)
J. Immunol.
, vol.158
, pp. 1989-1993
-
-
Bluestone, J.A.1
-
90
-
-
0030694234
-
The emerging role of CTLA-4 as an immune attenuator
-
90 Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity 1997; 7: 445-50.
-
(1997)
Immunity
, vol.7
, pp. 445-450
-
-
Thompson, C.B.1
Allison, J.P.2
-
91
-
-
0030873556
-
Differential requirements for survival and proliferation of CD8 naive or memory T cells
-
91 Tanchot C, Lemonnier FA, Perarnau B, Freitas AA, Rocha B. Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 1997; 276: 2057-62.
-
(1997)
Science
, vol.276
, pp. 2057-2062
-
-
Tanchot, C.1
Lemonnier, F.A.2
Perarnau, B.3
Freitas, A.A.4
Rocha, B.5
-
92
-
-
0028500255
-
Absence of B7-dependent responses in CD28-deficient mice
-
92 Green JM, Noel PJ, Sperling Al et al. Absence of B7-dependent responses in CD28-deficient mice. Immunity 1994; 1: 501-8.
-
(1994)
Immunity
, vol.1
, pp. 501-508
-
-
Green, J.M.1
Noel, P.J.2
Sperling, Al.3
|