-
2
-
-
79959389010
-
AAA+ proteases: ATP-fueled machines of protein destruction
-
Sauer R.T., Baker T.A. AAA+ proteases: ATP-fueled machines of protein destruction. Annu. Rev. Biochem. 2011, 80:587-611.
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 587-611
-
-
Sauer, R.T.1
Baker, T.A.2
-
3
-
-
0023184358
-
A multiple-component, ATP-dependent protease from Escherichia coli
-
Katayama-Fujimura Y., Gottesman S., Maurizi M.R. A multiple-component, ATP-dependent protease from Escherichia coli. J. Biol. Chem. 1987, 262:4477-4485.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 4477-4485
-
-
Katayama-Fujimura, Y.1
Gottesman, S.2
Maurizi, M.R.3
-
4
-
-
0023752052
-
The two-component, ATP-dependent Clp protease of Escherichia coli. Purification, cloning, and mutational analysis of the ATP-binding component
-
Katayama Y., Gottesman S., Pumphrey J., Rudikoff S., Clark W.P., Maurizi M.R. The two-component, ATP-dependent Clp protease of Escherichia coli. Purification, cloning, and mutational analysis of the ATP-binding component. J. Biol. Chem. 1988, 263:15226-15236.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15226-15236
-
-
Katayama, Y.1
Gottesman, S.2
Pumphrey, J.3
Rudikoff, S.4
Clark, W.P.5
Maurizi, M.R.6
-
5
-
-
0023906054
-
Protease Ti, a new ATP-dependent protease in Escherichia coli, contains protein-activated ATPase and proteolytic functions in distinct subunits
-
Hwang B.J., Woo K.M., Goldberg A.L., Chung C.H. Protease Ti, a new ATP-dependent protease in Escherichia coli, contains protein-activated ATPase and proteolytic functions in distinct subunits. J. Biol. Chem. 1988, 263:8727-8734.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 8727-8734
-
-
Hwang, B.J.1
Woo, K.M.2
Goldberg, A.L.3
Chung, C.H.4
-
6
-
-
0027519423
-
Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli
-
Wojtkowiak D., Georgopoulos C., Zylicz M. Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli. J. Biol. Chem. 1993, 268:22609-22617.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22609-22617
-
-
Wojtkowiak, D.1
Georgopoulos, C.2
Zylicz, M.3
-
7
-
-
0027364289
-
ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities
-
Gottesman S., Clark W.P., de Crecy-Lagard V., Maurizi M.R. ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities. J. Biol. Chem. 1993, 268:22618-22626.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22618-22626
-
-
Gottesman, S.1
Clark, W.P.2
de Crecy-Lagard, V.3
Maurizi, M.R.4
-
8
-
-
0028863006
-
Disassembly of the Mu transposase tetramer by the ClpX chaperone
-
Levchenko I., Luo L., Baker T.A. Disassembly of the Mu transposase tetramer by the ClpX chaperone. Genes Dev. 1995, 9:2399-2408.
-
(1995)
Genes Dev.
, vol.9
, pp. 2399-2408
-
-
Levchenko, I.1
Luo, L.2
Baker, T.A.3
-
9
-
-
0030020897
-
ClpX protein of Escherichia coli activates bacteriophage Mu transposase in the strand transfer complex for initiation of Mu DNA synthesis
-
Kruklitis R., Welty D.J., Nakai H. ClpX protein of Escherichia coli activates bacteriophage Mu transposase in the strand transfer complex for initiation of Mu DNA synthesis. EMBO J. 1996, 15:935-944.
-
(1996)
EMBO J.
, vol.15
, pp. 935-944
-
-
Kruklitis, R.1
Welty, D.J.2
Nakai, H.3
-
10
-
-
0032524297
-
Enzymatic and structural similarities between the Escherichia coli ATP-dependent proteases, ClpXP and ClpAP
-
Grimaud R., Kessel M., Beuron F., Steven A.C., Maurizi M.R. Enzymatic and structural similarities between the Escherichia coli ATP-dependent proteases, ClpXP and ClpAP. J. Biol. Chem. 1998, 273:12476-12481.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12476-12481
-
-
Grimaud, R.1
Kessel, M.2
Beuron, F.3
Steven, A.C.4
Maurizi, M.R.5
-
11
-
-
0033638255
-
Dynamics of substrate denaturation and translocation by the ClpXP degradation machine
-
Kim Y.I., Burton R.E., Burton B.M., Sauer R.T., Baker T.A. Dynamics of substrate denaturation and translocation by the ClpXP degradation machine. Mol. Cell 2000, 5:639-648.
-
(2000)
Mol. Cell
, vol.5
, pp. 639-648
-
-
Kim, Y.I.1
Burton, R.E.2
Burton, B.M.3
Sauer, R.T.4
Baker, T.A.5
-
12
-
-
0036848756
-
Characterization of a specificity factor for an AAA+ ATPase: assembly of SspB dimers with ssrA-tagged proteins and the ClpX hexamer
-
Wah D.A., Levchenko I., Baker T.A., Sauer R.T. Characterization of a specificity factor for an AAA+ ATPase: assembly of SspB dimers with ssrA-tagged proteins and the ClpX hexamer. Chem. Biol. 2002, 9:1237-1245.
-
(2002)
Chem. Biol.
, vol.9
, pp. 1237-1245
-
-
Wah, D.A.1
Levchenko, I.2
Baker, T.A.3
Sauer, R.T.4
-
13
-
-
2542443628
-
Communication between ClpX and ClpP during substrate processing and degradation
-
Joshi S.A., Hersch G.L., Baker T.A., Sauer R.T. Communication between ClpX and ClpP during substrate processing and degradation. Nat. Struct. Mol. Biol. 2004, 11:404-411.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 404-411
-
-
Joshi, S.A.1
Hersch, G.L.2
Baker, T.A.3
Sauer, R.T.4
-
14
-
-
21244482459
-
Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine
-
Hersch G.L., Burton R.E., Bolon D.N., Baker T.A., Sauer R.T. Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine. Cell 2005, 121:1017-1027.
-
(2005)
Cell
, vol.121
, pp. 1017-1027
-
-
Hersch, G.L.1
Burton, R.E.2
Bolon, D.N.3
Baker, T.A.4
Sauer, R.T.5
-
15
-
-
1242289869
-
The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function
-
Wojtyra U.A., Thibault G., Tuite A., Houry W.A. The N-terminal zinc binding domain of ClpX is a dimerization domain that modulates the chaperone function. J. Biol. Chem. 2003, 278:48981-48990.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48981-48990
-
-
Wojtyra, U.A.1
Thibault, G.2
Tuite, A.3
Houry, W.A.4
-
16
-
-
1242322964
-
Solution structure of the dimeric zinc binding domain of the chaperone ClpX
-
Donaldson L.W., Wojtyra U., Houry W.A. Solution structure of the dimeric zinc binding domain of the chaperone ClpX. J. Biol. Chem. 2003, 278:48991-48996.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48991-48996
-
-
Donaldson, L.W.1
Wojtyra, U.2
Houry, W.A.3
-
17
-
-
33847108004
-
Structural basis of SspB-tail recognition by the zinc binding domain of ClpX
-
Park E.Y., Lee B.G., Hong S.B., Kim H.W., Jeon H., Song H.K. Structural basis of SspB-tail recognition by the zinc binding domain of ClpX. J. Mol. Biol. 2007, 367:514-526.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 514-526
-
-
Park, E.Y.1
Lee, B.G.2
Hong, S.B.3
Kim, H.W.4
Jeon, H.5
Song, H.K.6
-
18
-
-
70350772363
-
Crystal structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine
-
Glynn S.E., Martin A., Nager A.R., Baker T.A., Sauer R.T. Crystal structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell 2009, 139:744-756.
-
(2009)
Cell
, vol.139
, pp. 744-756
-
-
Glynn, S.E.1
Martin, A.2
Nager, A.R.3
Baker, T.A.4
Sauer, R.T.5
-
19
-
-
0348010311
-
Crystal structure of ClpX molecular chaperone from Helicobacter pylori
-
Kim D.Y., Kim K.K. Crystal structure of ClpX molecular chaperone from Helicobacter pylori. J. Biol. Chem. 2003, 278:50664-50670.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50664-50670
-
-
Kim, D.Y.1
Kim, K.K.2
-
20
-
-
0032969563
-
AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
-
Neuwald A.F., Aravind L., Spouge J.L., Koonin E.V. AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res. 1999, 9:27-43.
-
(1999)
Genome Res.
, vol.9
, pp. 27-43
-
-
Neuwald, A.F.1
Aravind, L.2
Spouge, J.L.3
Koonin, E.V.4
-
21
-
-
33745041480
-
Evolutionary relationships and structural mechanisms of AAA+ proteins
-
Erzberger J.P., Berger J.M. Evolutionary relationships and structural mechanisms of AAA+ proteins. Annu. Rev. Biophys. Biomol. Struct. 2006, 35:93-114.
-
(2006)
Annu. Rev. Biophys. Biomol. Struct.
, vol.35
, pp. 93-114
-
-
Erzberger, J.P.1
Berger, J.M.2
-
22
-
-
0035800729
-
Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis
-
Singh S.K., Rozycki J., Ortega J., Ishikawa T., Lo J., Steven A.C., Maurizi M.R. Functional domains of the ClpA and ClpX molecular chaperones identified by limited proteolysis and deletion analysis. J. Biol. Chem. 2001, 276:29420-29429.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29420-29429
-
-
Singh, S.K.1
Rozycki, J.2
Ortega, J.3
Ishikawa, T.4
Lo, J.5
Steven, A.C.6
Maurizi, M.R.7
-
23
-
-
27144474906
-
Rebuilt AAA+ motors reveal operating principles for ATP-fueled machines
-
Martin A., Baker T.A., Sauer R.T. Rebuilt AAA+ motors reveal operating principles for ATP-fueled machines. Nature 2005, 437:1115-1120.
-
(2005)
Nature
, vol.437
, pp. 1115-1120
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
24
-
-
34250850205
-
Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease
-
Martin A., Baker T.A., Sauer R.T. Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease. Mol. Cell 2007, 27:41-52.
-
(2007)
Mol. Cell
, vol.27
, pp. 41-52
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
25
-
-
0030048167
-
Bacteriophage Mu repressor as a target for the Escherichia coli ATP-dependent Clp protease
-
Laachouch J.E., Desmet L., Geuskens V., Grimaud R., Toussaint A. Bacteriophage Mu repressor as a target for the Escherichia coli ATP-dependent Clp protease. EMBO J. 1996, 15:437-444.
-
(1996)
EMBO J.
, vol.15
, pp. 437-444
-
-
Laachouch, J.E.1
Desmet, L.2
Geuskens, V.3
Grimaud, R.4
Toussaint, A.5
-
26
-
-
0030908043
-
ClpX and MuB interact with overlapping regions of Mu transposase: implications for control of the transposition pathway
-
Levchenko I., Yamauchi M., Baker T.A. ClpX and MuB interact with overlapping regions of Mu transposase: implications for control of the transposition pathway. Genes Dev. 1997, 11:1561-1572.
-
(1997)
Genes Dev.
, vol.11
, pp. 1561-1572
-
-
Levchenko, I.1
Yamauchi, M.2
Baker, T.A.3
-
27
-
-
33646021005
-
Proteomic profiling of ClpXP substrates following DNA damage reveals extensive instability within SOS regulon
-
Neher S.B., Villen J., Oakes E., Bakalarski C., Sauer R.T., Gygi S.P., Baker T.A. Proteomic profiling of ClpXP substrates following DNA damage reveals extensive instability within SOS regulon. Mol. Cell 2006, 22:193-204.
-
(2006)
Mol. Cell
, vol.22
, pp. 193-204
-
-
Neher, S.B.1
Villen, J.2
Oakes, E.3
Bakalarski, C.4
Sauer, R.T.5
Gygi, S.P.6
Baker, T.A.7
-
28
-
-
0032079329
-
The ClpXP and ClpAP proteases degrade proteins with C-terminal peptide tails added by the SsrA tagging system
-
Gottesman S., Roche E., Zhou Y.N., Sauer R.T. The ClpXP and ClpAP proteases degrade proteins with C-terminal peptide tails added by the SsrA tagging system. Genes Dev. 1998, 12:1338-1347.
-
(1998)
Genes Dev.
, vol.12
, pp. 1338-1347
-
-
Gottesman, S.1
Roche, E.2
Zhou, Y.N.3
Sauer, R.T.4
-
29
-
-
0030024281
-
Role of a peptide-tagging system in degradation of proteins translated from damaged mRNA
-
Keiler K.C., Waller P.R.H., Sauer R.T. Role of a peptide-tagging system in degradation of proteins translated from damaged mRNA. Science 1996, 271:990-993.
-
(1996)
Science
, vol.271
, pp. 990-993
-
-
Keiler, K.C.1
Waller, P.R.H.2
Sauer, R.T.3
-
30
-
-
34247103448
-
The tmRNA system for translational surveillance and ribosome rescue
-
Moore S.E., Sauer R.T. The tmRNA system for translational surveillance and ribosome rescue. Annu. Rev. Biochem. 2007, 76:101-124.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 101-124
-
-
Moore, S.E.1
Sauer, R.T.2
-
31
-
-
0034254908
-
Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP
-
Singh S.K., Grimaud R., Hoskins J.R., Wickner S., Maurizi M.R. Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:8898-8903.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 8898-8903
-
-
Singh, S.K.1
Grimaud, R.2
Hoskins, J.R.3
Wickner, S.4
Maurizi, M.R.5
-
32
-
-
0035266072
-
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal
-
Lee C., Schwartz M.P., Prakash S., Iwakura M., Matouschek A. ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal. Mol. Cell 2001, 7:627-637.
-
(2001)
Mol. Cell
, vol.7
, pp. 627-637
-
-
Lee, C.1
Schwartz, M.P.2
Prakash, S.3
Iwakura, M.4
Matouschek, A.5
-
33
-
-
0035875890
-
Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine
-
Burton R.E., Siddiqui S.M., Kim Y.I., Baker T.A., Sauer R.T. Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine. EMBO J. 2001, 20:3092-3100.
-
(2001)
EMBO J.
, vol.20
, pp. 3092-3100
-
-
Burton, R.E.1
Siddiqui, S.M.2
Kim, Y.I.3
Baker, T.A.4
Sauer, R.T.5
-
34
-
-
0042329502
-
Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine
-
Kenniston J.A., Baker T.A., Fernandez J.M., Sauer R.T. Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine. Cell 2003, 114:511-520.
-
(2003)
Cell
, vol.114
, pp. 511-520
-
-
Kenniston, J.A.1
Baker, T.A.2
Fernandez, J.M.3
Sauer, R.T.4
-
35
-
-
1642308732
-
Effects of local protein stability and the geometric position of the substrate degradation tag on the efficiency of ClpXP denaturation and degradation
-
Kenniston J.A., Burton R.E., Siddiqui S.M., Baker T.A., Sauer R.T. Effects of local protein stability and the geometric position of the substrate degradation tag on the efficiency of ClpXP denaturation and degradation. J. Struct. Biol. 2004, 146:130-140.
-
(2004)
J. Struct. Biol.
, vol.146
, pp. 130-140
-
-
Kenniston, J.A.1
Burton, R.E.2
Siddiqui, S.M.3
Baker, T.A.4
Sauer, R.T.5
-
36
-
-
79953888421
-
Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine
-
Aubin-Tam M.E., Olivares A.O., Sauer R.T., Baker T.A., Lang M.J. Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine. Cell 2011, 145:257-267.
-
(2011)
Cell
, vol.145
, pp. 257-267
-
-
Aubin-Tam, M.E.1
Olivares, A.O.2
Sauer, R.T.3
Baker, T.A.4
Lang, M.J.5
-
37
-
-
0035845498
-
Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis
-
Flynn J.M., Levchenko I., Seidel M., Wickner S.H., Sauer R.T., Baker T.A. Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis. Proc. Natl. Acad. Sci. U.S.A. 2001, 11:10584-10589.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.11
, pp. 10584-10589
-
-
Flynn, J.M.1
Levchenko, I.2
Seidel, M.3
Wickner, S.H.4
Sauer, R.T.5
Baker, T.A.6
-
38
-
-
0034730496
-
A specificity-enhancing factor for the ClpXP degradation machine
-
Levchenko I., Seidel M., Sauer R.T., Baker T.A. A specificity-enhancing factor for the ClpXP degradation machine. Science 2000, 289:2354-2356.
-
(2000)
Science
, vol.289
, pp. 2354-2356
-
-
Levchenko, I.1
Seidel, M.2
Sauer, R.T.3
Baker, T.A.4
-
39
-
-
0037351068
-
Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signals
-
Flynn J.M., Neher S.B., Kim Y.I., Sauer R.T., Baker T.A. Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signals. Mol. Cell 2003, 11:671-683.
-
(2003)
Mol. Cell
, vol.11
, pp. 671-683
-
-
Flynn, J.M.1
Neher, S.B.2
Kim, Y.I.3
Sauer, R.T.4
Baker, T.A.5
-
40
-
-
0033553474
-
Recognition, targeting, and hydrolysis of the lambda O replication protein by the ClpP/ClpX protease
-
Gonciarz-Swiatek M., Wawrzynow A., Um S.J., Learn B.A., McMacken R., Kelley W.L., Georgopoulos C., Sliekers O., Zylicz M. Recognition, targeting, and hydrolysis of the lambda O replication protein by the ClpP/ClpX protease. J. Biol. Chem. 1999, 274:13999-14005.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13999-14005
-
-
Gonciarz-Swiatek, M.1
Wawrzynow, A.2
Um, S.J.3
Learn, B.A.4
McMacken, R.5
Kelley, W.L.6
Georgopoulos, C.7
Sliekers, O.8
Zylicz, M.9
-
41
-
-
39549084936
-
Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates
-
Martin A., Baker T.A., Sauer R.T. Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates. Mol. Cell 2008, 29:441-450.
-
(2008)
Mol. Cell
, vol.29
, pp. 441-450
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
42
-
-
1542283751
-
Role of the protein-processing pore of ClpX, an AAA+ ATPase, in recognition and engagement of specific protein substrates
-
Siddiqui S.M., Sauer R.T., Baker T.A. Role of the protein-processing pore of ClpX, an AAA+ ATPase, in recognition and engagement of specific protein substrates. Genes Dev. 2004, 18:369-374.
-
(2004)
Genes Dev.
, vol.18
, pp. 369-374
-
-
Siddiqui, S.M.1
Sauer, R.T.2
Baker, T.A.3
-
43
-
-
55549088522
-
Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding
-
Martin A., Baker T.A., Sauer R.T. Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding. Nat. Struct. Mol. Biol. 2008, 15:1147-1151.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 1147-1151
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
44
-
-
33845981507
-
Altered specificity of a AAA+ protease
-
Farrell C.M., Baker T.A., Sauer R.T. Altered specificity of a AAA+ protease. Mol. Cell 2007, 25:161-166.
-
(2007)
Mol. Cell
, vol.25
, pp. 161-166
-
-
Farrell, C.M.1
Baker, T.A.2
Sauer, R.T.3
-
45
-
-
0345687188
-
Distinct peptide signals in the UmuD and UmuD' Subunits of UmuD/D' mediate tethering and substrate-processing by the ClpXP protease
-
Neher S.B., Sauer R.T., Baker T.A. Distinct peptide signals in the UmuD and UmuD' Subunits of UmuD/D' mediate tethering and substrate-processing by the ClpXP protease. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:13219-13224.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 13219-13224
-
-
Neher, S.B.1
Sauer, R.T.2
Baker, T.A.3
-
46
-
-
0034596991
-
Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability
-
Gonzalez M., Rasulova F., Maurizi M.R., Woodgate R. Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability. EMBO J. 2000, 19:5251-5258.
-
(2000)
EMBO J.
, vol.19
, pp. 5251-5258
-
-
Gonzalez, M.1
Rasulova, F.2
Maurizi, M.R.3
Woodgate, R.4
-
47
-
-
0028359550
-
A new component of bacteriophage Mu replicative transposition machinery: the Escherichia coli ClpX protein
-
Mhammedi-Alaoui A., Pato M., Gama M.J., Toussaint A. A new component of bacteriophage Mu replicative transposition machinery: the Escherichia coli ClpX protein. Mol. Microbiol. 1994, 11:1109-1116.
-
(1994)
Mol. Microbiol.
, vol.11
, pp. 1109-1116
-
-
Mhammedi-Alaoui, A.1
Pato, M.2
Gama, M.J.3
Toussaint, A.4
-
48
-
-
41549163391
-
Unique contacts direct high-priority recognition of the tetrameric transposase-DNA complex by the AAA+ unfoldase ClpX
-
Abdelhakim A.H., Oakes E.S.C., Sauer R.T., Baker T.A. Unique contacts direct high-priority recognition of the tetrameric transposase-DNA complex by the AAA+ unfoldase ClpX. Mol. Cell 2008, 11:39-50.
-
(2008)
Mol. Cell
, vol.11
, pp. 39-50
-
-
Abdelhakim, A.H.1
Oakes, E.S.C.2
Sauer, R.T.3
Baker, T.A.4
-
49
-
-
4444377383
-
Modulating substrate choice: the SspB adaptor delivers a regulator of the extracytoplasmic-stress response to the AAA+ protease ClpXP for degradation
-
Flynn J.F., Levchenko I., Sauer R.T., Baker T.A. Modulating substrate choice: the SspB adaptor delivers a regulator of the extracytoplasmic-stress response to the AAA+ protease ClpXP for degradation. Genes Dev. 2004, 18:2292-2301.
-
(2004)
Genes Dev.
, vol.18
, pp. 2292-2301
-
-
Flynn, J.F.1
Levchenko, I.2
Sauer, R.T.3
Baker, T.A.4
-
50
-
-
0035281566
-
The RssB response regulator directly targets sigma(S) for degradation by ClpXP
-
Zhou Y., Gottesman S., Hoskins J.R., Maurizi M.R., Wickner S. The RssB response regulator directly targets sigma(S) for degradation by ClpXP. Genes Dev. 2001, 15:627-637.
-
(2001)
Genes Dev.
, vol.15
, pp. 627-637
-
-
Zhou, Y.1
Gottesman, S.2
Hoskins, J.R.3
Maurizi, M.R.4
Wickner, S.5
-
51
-
-
71749093772
-
Proteolysis of sigmaS (RpoS) and the general stress response in Escherichia coli
-
Hengge R. Proteolysis of sigmaS (RpoS) and the general stress response in Escherichia coli. Res. Microbiol. 2009, 160:667-676.
-
(2009)
Res. Microbiol.
, vol.160
, pp. 667-676
-
-
Hengge, R.1
-
52
-
-
0141992126
-
Structure of a delivery protein for a AAA+ protease in complex with a peptide degradation tag
-
Levchenko I., Grant R.A., Wah D.A., Sauer R.T., Baker T.A. Structure of a delivery protein for a AAA+ protease in complex with a peptide degradation tag. Mol. Cell 2003, 12:365-372.
-
(2003)
Mol. Cell
, vol.12
, pp. 365-372
-
-
Levchenko, I.1
Grant, R.A.2
Wah, D.A.3
Sauer, R.T.4
Baker, T.A.5
-
53
-
-
0043128700
-
Structural basis of degradation signal recognition by SspB, a specificity-enhancing factor for the ClpXP proteolytic machine
-
Song H.K., Eck M.J. Structural basis of degradation signal recognition by SspB, a specificity-enhancing factor for the ClpXP proteolytic machine. Mol. Cell 2003, 12:75-86.
-
(2003)
Mol. Cell
, vol.12
, pp. 75-86
-
-
Song, H.K.1
Eck, M.J.2
-
54
-
-
0141888401
-
Flexible linkers leash the substrate-binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease
-
Wah D.A., Levchenko I., Rieckhof G.E., Bolon D.N., Baker T.A., Sauer R.T. Flexible linkers leash the substrate-binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease. Mol. Cell 2003, 12:355-363.
-
(2003)
Mol. Cell
, vol.12
, pp. 355-363
-
-
Wah, D.A.1
Levchenko, I.2
Rieckhof, G.E.3
Bolon, D.N.4
Baker, T.A.5
Sauer, R.T.6
-
55
-
-
0141957392
-
Targeted delivery of an ssrA-tagged substrate by the adaptor protein SspB to its cognate AAA+ protein ClpX
-
Dougan D.A., Weber-Ban E., Bukau B. Targeted delivery of an ssrA-tagged substrate by the adaptor protein SspB to its cognate AAA+ protein ClpX. Mol. Cell 2003, 12:373-380.
-
(2003)
Mol. Cell
, vol.12
, pp. 373-380
-
-
Dougan, D.A.1
Weber-Ban, E.2
Bukau, B.3
-
56
-
-
1242271992
-
Bivalent tethering of SspB to ClpXP is required for efficient substrate delivery: a protein-design study
-
Bolon D.N., Wah D.A., Hersch G.L., Baker T.A., Sauer R.T. Bivalent tethering of SspB to ClpXP is required for efficient substrate delivery: a protein-design study. Mol. Cell 2004, 13:443-449.
-
(2004)
Mol. Cell
, vol.13
, pp. 443-449
-
-
Bolon, D.N.1
Wah, D.A.2
Hersch, G.L.3
Baker, T.A.4
Sauer, R.T.5
-
57
-
-
4344658879
-
SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags
-
Hersch G.L., Baker T.A., Sauer R.T. SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:12136-12141.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 12136-12141
-
-
Hersch, G.L.1
Baker, T.A.2
Sauer, R.T.3
-
58
-
-
5344266886
-
Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease
-
Bolon D.N., Grant R.A., Baker T.A., Sauer R.T. Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease. Mol. Cell 2004, 16:343-350.
-
(2004)
Mol. Cell
, vol.16
, pp. 343-350
-
-
Bolon, D.N.1
Grant, R.A.2
Baker, T.A.3
Sauer, R.T.4
-
59
-
-
2442563573
-
Regulation of the Escherichia coli sigma-dependent envelope stress response
-
Alba B.M., Gross C.A. Regulation of the Escherichia coli sigma-dependent envelope stress response. Mol. Microbiol. 2004, 52:613-619.
-
(2004)
Mol. Microbiol.
, vol.52
, pp. 613-619
-
-
Alba, B.M.1
Gross, C.A.2
-
60
-
-
33846134757
-
Design principles of the proteolytic cascade governing the sigmaE-mediated envelope stress response in Escherichia coli: keys to graded, buffered, and rapid signal transduction
-
Chaba R., Grigorova I.L., Flynn J.M., Baker T.A., Gross C.A. Design principles of the proteolytic cascade governing the sigmaE-mediated envelope stress response in Escherichia coli: keys to graded, buffered, and rapid signal transduction. Genes Dev. 2007, 21:124-136.
-
(2007)
Genes Dev.
, vol.21
, pp. 124-136
-
-
Chaba, R.1
Grigorova, I.L.2
Flynn, J.M.3
Baker, T.A.4
Gross, C.A.5
-
61
-
-
22444444406
-
Versatile modes of peptide recognition by the AAA+ adaptor protein SspB
-
Levchenko I., Grant R.A., Flynn J.M., Sauer R.T., Baker T.A. Versatile modes of peptide recognition by the AAA+ adaptor protein SspB. Nat. Struct. Mol. Biol. 2005, 12:520-525.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 520-525
-
-
Levchenko, I.1
Grant, R.A.2
Flynn, J.M.3
Sauer, R.T.4
Baker, T.A.5
-
62
-
-
33744518327
-
Engineering controllable protein degradation
-
McGinness K.E., Baker T.A., Sauer R.T. Engineering controllable protein degradation. Mol. Cell 2006, 22:701-707.
-
(2006)
Mol. Cell
, vol.22
, pp. 701-707
-
-
McGinness, K.E.1
Baker, T.A.2
Sauer, R.T.3
-
63
-
-
34249655060
-
Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery
-
McGinness K.E., Bolon D.N., Kaganovich M., Baker T.A., Sauer R.T. Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery. J. Biol. Chem. 2007, 282:11465-11473.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11465-11473
-
-
McGinness, K.E.1
Bolon, D.N.2
Kaganovich, M.3
Baker, T.A.4
Sauer, R.T.5
-
64
-
-
54249169161
-
Inducible protein degradation in Bacillus subtilis using heterologous peptide tags and adaptor proteins to target substrates to the protease ClpXP
-
Griffith K.L., Grossman A.D. Inducible protein degradation in Bacillus subtilis using heterologous peptide tags and adaptor proteins to target substrates to the protease ClpXP. Mol. Microbiol. 2008, 70:1012-1025.
-
(2008)
Mol. Microbiol.
, vol.70
, pp. 1012-1025
-
-
Griffith, K.L.1
Grossman, A.D.2
-
65
-
-
79953701962
-
Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase
-
Kim J.H., Wei J.R., Wallach J.B., Robbins R.S., Rubin E.J., Schnappinger D. Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase. Nucleic Acids Res. 2011, 39:2210-2220.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 2210-2220
-
-
Kim, J.H.1
Wei, J.R.2
Wallach, J.B.3
Robbins, R.S.4
Rubin, E.J.5
Schnappinger, D.6
-
66
-
-
69249134629
-
Engineering synthetic adaptors and substrates for controlled ClpXP degradation
-
Davis J.H., Baker T.A., Sauer R.T. Engineering synthetic adaptors and substrates for controlled ClpXP degradation. J. Biol. Chem. 2009, 14:21848-21855.
-
(2009)
J. Biol. Chem.
, vol.14
, pp. 21848-21855
-
-
Davis, J.H.1
Baker, T.A.2
Sauer, R.T.3
-
67
-
-
26944431987
-
Ribosome rescue: tmRNA tagging activity and capacity in Escherichia coli
-
Moore S.D., Sauer R.T. Ribosome rescue: tmRNA tagging activity and capacity in Escherichia coli. Mol. Micro. 2005, 58:456-466.
-
(2005)
Mol. Micro.
, vol.58
, pp. 456-466
-
-
Moore, S.D.1
Sauer, R.T.2
-
68
-
-
25144452838
-
Cytoplasmic degradation of ssrA-tagged proteins
-
Farrell C.M., Grossman A.D., Sauer R.T. Cytoplasmic degradation of ssrA-tagged proteins. Mol. Micro. 2005, 57:1750-1761.
-
(2005)
Mol. Micro.
, vol.57
, pp. 1750-1761
-
-
Farrell, C.M.1
Grossman, A.D.2
Sauer, R.T.3
-
69
-
-
53149091681
-
Turnover of endogenous SsrA-tagged proteins mediated by ATP-dependent proteases in Escherichia coli
-
Lies M., Maurizi M.R. Turnover of endogenous SsrA-tagged proteins mediated by ATP-dependent proteases in Escherichia coli. J. Biol. Chem. 2008, 283:22918-22929.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 22918-22929
-
-
Lies, M.1
Maurizi, M.R.2
-
70
-
-
60349096613
-
Controlled degradation by ClpXP protease tunes the levels of the excision repair protein UvrA to the extent of DNA damage
-
Pruteanu M., Baker T.A. Controlled degradation by ClpXP protease tunes the levels of the excision repair protein UvrA to the extent of DNA damage. Mol. Microbiol. 2009, 71:912-924.
-
(2009)
Mol. Microbiol.
, vol.71
, pp. 912-924
-
-
Pruteanu, M.1
Baker, T.A.2
-
72
-
-
27144460621
-
Dysregulation of bacterial proteolytic machinery by a new class of antibiotics
-
Brotz-Oesterhelt H., Beyer D., Kroll H.P., Endermann R., Ladel C., Schroeder W., Hinzen B., Raddatz S., Paulsen H., Henninger K., Bandow J.E., Sahl H.G., Labischinski H. Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nat. Med. 2005, 11:1082-1087.
-
(2005)
Nat. Med.
, vol.11
, pp. 1082-1087
-
-
Brotz-Oesterhelt, H.1
Beyer, D.2
Kroll, H.P.3
Endermann, R.4
Ladel, C.5
Schroeder, W.6
Hinzen, B.7
Raddatz, S.8
Paulsen, H.9
Henninger, K.10
Bandow, J.E.11
Sahl, H.G.12
Labischinski, H.13
-
73
-
-
71749110235
-
The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease
-
Kirstein J., Hoffmann A., Lilie H., Schmidt R., Rubsamen-Waigmann H., Brotz-Oesterhelt H., Mogk A., Turgay K. The antibiotic ADEP reprogrammes ClpP, switching it from a regulated to an uncontrolled protease. EMBO Mol. Med. 2009, 1:37-49.
-
(2009)
EMBO Mol. Med.
, vol.1
, pp. 37-49
-
-
Kirstein, J.1
Hoffmann, A.2
Lilie, H.3
Schmidt, R.4
Rubsamen-Waigmann, H.5
Brotz-Oesterhelt, H.6
Mogk, A.7
Turgay, K.8
-
74
-
-
0025358672
-
Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli
-
Maurizi M.R., Clark W.P., Katayama Y., Rudikoff S., Pumphrey J., Bowers B., Gottesman S. Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli. J. Biol. Chem. 1990, 265:12536-12545.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 12536-12545
-
-
Maurizi, M.R.1
Clark, W.P.2
Katayama, Y.3
Rudikoff, S.4
Pumphrey, J.5
Bowers, B.6
Gottesman, S.7
-
75
-
-
0029147711
-
Scanning transmission electron microscopy and small-angle scattering provide evidence that native Escherichia coli ClpP is a tetradecamer with an axial pore
-
Flanagan J.M., Wall J.S., Capel M.S., Schneider D.K., Shanklin J. Scanning transmission electron microscopy and small-angle scattering provide evidence that native Escherichia coli ClpP is a tetradecamer with an axial pore. Biochemistry 1995, 34:10910-10917.
-
(1995)
Biochemistry
, vol.34
, pp. 10910-10917
-
-
Flanagan, J.M.1
Wall, J.S.2
Capel, M.S.3
Schneider, D.K.4
Shanklin, J.5
-
76
-
-
0029126356
-
Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome
-
Kessel M., Maurizi M.R., Kim B., Kocsis E., Trus B.L., Singh S.K., Steven A.C. Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome. J. Mol. Biol. 1995, 250:587-594.
-
(1995)
J. Mol. Biol.
, vol.250
, pp. 587-594
-
-
Kessel, M.1
Maurizi, M.R.2
Kim, B.3
Kocsis, E.4
Trus, B.L.5
Singh, S.K.6
Steven, A.C.7
-
77
-
-
0030691115
-
The structure of ClpP at 2.3Å resolution suggests a model for ATP-dependent proteolysis
-
Wang J., Hartling J.A., Flanagan J.M. The structure of ClpP at 2.3Å resolution suggests a model for ATP-dependent proteolysis. Cell 1997, 91:447-456.
-
(1997)
Cell
, vol.91
, pp. 447-456
-
-
Wang, J.1
Hartling, J.A.2
Flanagan, J.M.3
-
78
-
-
0028305742
-
Activity and specificity of Escherichia coli ClpAP protease in cleaving model peptide substrates
-
Thompson M.W., Maurizi M.R. Activity and specificity of Escherichia coli ClpAP protease in cleaving model peptide substrates. J. Biol. Chem. 1994, 269:18201-18208.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18201-18208
-
-
Thompson, M.W.1
Maurizi, M.R.2
-
79
-
-
0028365133
-
Processive degradation of proteins by the ATP-dependent Clp protease from Escherichia coli. Requirement for the multiple array of active sites in ClpP but not ATP hydrolysis
-
Thompson M.W., Singh S.K., Maurizi M.R. Processive degradation of proteins by the ATP-dependent Clp protease from Escherichia coli. Requirement for the multiple array of active sites in ClpP but not ATP hydrolysis. J. Biol. Chem. 1994, 269:18209-18215.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18209-18215
-
-
Thompson, M.W.1
Singh, S.K.2
Maurizi, M.R.3
-
80
-
-
33749247217
-
Crystal structure at 1.9Å of E. coli ClpP with a peptide covalently bound at the active site
-
Szyk A., Maurizi M.R. Crystal structure at 1.9Å of E. coli ClpP with a peptide covalently bound at the active site. J. Struct. Biol. 2006, 156:165-174.
-
(2006)
J. Struct. Biol.
, vol.156
, pp. 165-174
-
-
Szyk, A.1
Maurizi, M.R.2
-
81
-
-
44149116183
-
The structural basis for the activation and peptide recognition of bacterial ClpP
-
Kim D.Y., Kim K.K. The structural basis for the activation and peptide recognition of bacterial ClpP. J. Mol. Biol. 2008, 379:760-771.
-
(2008)
J. Mol. Biol.
, vol.379
, pp. 760-771
-
-
Kim, D.Y.1
Kim, K.K.2
-
83
-
-
77953694169
-
Control of substrate gating and translocation into ClpP by channel residues and ClpX binding
-
Lee M.E., Baker T.A., Sauer R.T. Control of substrate gating and translocation into ClpP by channel residues and ClpX binding. J. Mol. Biol. 2010, 399:707-718.
-
(2010)
J. Mol. Biol.
, vol.399
, pp. 707-718
-
-
Lee, M.E.1
Baker, T.A.2
Sauer, R.T.3
-
84
-
-
7444254844
-
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
-
Kang S.G., Maurizi M.R., Thompson M., Mueser T., Ahvazi B. Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP. J. Struct. Biol. 2004, 148:338-352.
-
(2004)
J. Struct. Biol.
, vol.148
, pp. 338-352
-
-
Kang, S.G.1
Maurizi, M.R.2
Thompson, M.3
Mueser, T.4
Ahvazi, B.5
-
85
-
-
18144426344
-
The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation
-
Gribun A., Kimber M.S., Ching R., Sprangers R., Fiebig K.M., Houry W.A. The ClpP double ring tetradecameric protease exhibits plastic ring-ring interactions, and the N termini of its subunits form flexible loops that are essential for ClpXP and ClpAP complex formation. J. Biol. Chem. 2005, 280:16185-16196.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16185-16196
-
-
Gribun, A.1
Kimber, M.S.2
Ching, R.3
Sprangers, R.4
Fiebig, K.M.5
Houry, W.A.6
-
86
-
-
31344467469
-
The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes
-
Bewley M.C., Graziano V., Griffin K., Flanagan J.M. The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes. J. Struct. Biol. 2006, 153:113-128.
-
(2006)
J. Struct. Biol.
, vol.153
, pp. 113-128
-
-
Bewley, M.C.1
Graziano, V.2
Griffin, K.3
Flanagan, J.M.4
-
87
-
-
33846654174
-
Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1
-
Ingvarsson H., Mate M.J., Hogbom M., Portnoi D., Benaroudj N., Alzari P.M., Ortiz-Lombardia M., Unge T. Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1. Acta Crystallogr. D Biol. Crystallogr. 2007, 63:249-259.
-
(2007)
Acta Crystallogr. D Biol. Crystallogr.
, vol.63
, pp. 249-259
-
-
Ingvarsson, H.1
Mate, M.J.2
Hogbom, M.3
Portnoi, D.4
Benaroudj, N.5
Alzari, P.M.6
Ortiz-Lombardia, M.7
Unge, T.8
-
88
-
-
58349103347
-
Turned on for degradation: ATPase-independent degradation by ClpP
-
Bewley M.C., Graziano V., Griffin K., Flanagan J.M. Turned on for degradation: ATPase-independent degradation by ClpP. J. Struct. Biol. 2009, 165:118-125.
-
(2009)
J. Struct. Biol.
, vol.165
, pp. 118-125
-
-
Bewley, M.C.1
Graziano, V.2
Griffin, K.3
Flanagan, J.M.4
-
89
-
-
77956947687
-
Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: a model for the ClpX/ClpA-bound state of ClpP
-
Li D.H., Chung Y.S., Gloyd M., Joseph E., Ghirlando R., Wright G.D., Cheng Y.Q., Maurizi M.R., Guarné A., Ortega J. Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: a model for the ClpX/ClpA-bound state of ClpP. Chem. Biol. 2010, 17:959-969.
-
(2010)
Chem. Biol.
, vol.17
, pp. 959-969
-
-
Li, D.H.1
Chung, Y.S.2
Gloyd, M.3
Joseph, E.4
Ghirlando, R.5
Wright, G.D.6
Cheng, Y.Q.7
Maurizi, M.R.8
Guarné, A.9
Ortega, J.10
-
90
-
-
77950519954
-
Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
-
Lee B.G., Park E.Y., Lee K.E., Jeon H., Sung K.H., Paulsen H., Rübsamen-Schaeff H., Brötz-Oesterhelt H., Song H.K. Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism. Nat. Struct. Mol. Biol. 2010, 17:471-478.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 471-478
-
-
Lee, B.G.1
Park, E.Y.2
Lee, K.E.3
Jeon, H.4
Sung, K.H.5
Paulsen, H.6
Rübsamen-Schaeff, H.7
Brötz-Oesterhelt, H.8
Song, H.K.9
-
91
-
-
34447511284
-
ClpP: a distinctive family of cylindrical energy-dependent serine proteases
-
Yu A.Y., Houry W.A. ClpP: a distinctive family of cylindrical energy-dependent serine proteases. FEBS Lett. 2007, 581:3749-3757.
-
(2007)
FEBS Lett.
, vol.581
, pp. 3749-3757
-
-
Yu, A.Y.1
Houry, W.A.2
-
92
-
-
0032568504
-
Molecular properties of ClpAP protease of Escherichia coli: ATP-dependent association of ClpA and ClpP
-
Maurizi M.R., Singh S.K., Thompson M.W., Kessel M., Ginsburg A. Molecular properties of ClpAP protease of Escherichia coli: ATP-dependent association of ClpA and ClpP. Biochemistry 1998, 37:7778-7786.
-
(1998)
Biochemistry
, vol.37
, pp. 7778-7786
-
-
Maurizi, M.R.1
Singh, S.K.2
Thompson, M.W.3
Kessel, M.4
Ginsburg, A.5
-
93
-
-
27444440627
-
Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX
-
Kang S.G., Dimitrova M.N., Ortega J., Ginsburg A., Maurizi M.R. Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J. Biol. Chem. 2005, 280:35424-35432.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35424-35432
-
-
Kang, S.G.1
Dimitrova, M.N.2
Ortega, J.3
Ginsburg, A.4
Maurizi, M.R.5
-
94
-
-
77954636793
-
Structural and theoretical studies indicate that the cylindrical protease ClpP samples extended and compact conformations
-
Kimber M.S., Yu A.Y., Borg M., Leung E., Chan H.S., Houry W.A. Structural and theoretical studies indicate that the cylindrical protease ClpP samples extended and compact conformations. Structure 2010, 18:798-808.
-
(2010)
Structure
, vol.18
, pp. 798-808
-
-
Kimber, M.S.1
Yu, A.Y.2
Borg, M.3
Leung, E.4
Chan, H.S.5
Houry, W.A.6
-
95
-
-
28044440088
-
Quantitative NMR spectroscopy of supramolecular complexes: dynamic side pores in ClpP are important for product release
-
Sprangers R., Gribun A., Hwang P.M., Houry W.A., Kay L.E. Quantitative NMR spectroscopy of supramolecular complexes: dynamic side pores in ClpP are important for product release. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:16678-16683.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 16678-16683
-
-
Sprangers, R.1
Gribun, A.2
Hwang, P.M.3
Houry, W.A.4
Kay, L.E.5
-
96
-
-
0034502532
-
Visualization of substrate binding and translocation by the ATP-dependent protease, ClpXP
-
Ortega J., Singh S.K., Ishikawa T., Maurizi M.R., Steven A.C. Visualization of substrate binding and translocation by the ATP-dependent protease, ClpXP. Mol. Cell 2000, 6:1515-1521.
-
(2000)
Mol. Cell
, vol.6
, pp. 1515-1521
-
-
Ortega, J.1
Singh, S.K.2
Ishikawa, T.3
Maurizi, M.R.4
Steven, A.C.5
-
97
-
-
0037119954
-
Alternating translocation of protein substrates from both ends of ClpXP protease
-
Ortega J., Lee H.S., Maurizi M.R., Steven A.C. Alternating translocation of protein substrates from both ends of ClpXP protease. EMBO J. 2002, 21:4938-4949.
-
(2002)
EMBO J.
, vol.21
, pp. 4938-4949
-
-
Ortega, J.1
Lee, H.S.2
Maurizi, M.R.3
Steven, A.C.4
-
98
-
-
54349084780
-
The ClpP N-terminus coordinates substrate access with protease active site reactivity
-
Jennings L.D., Bohon J., Chance M.R., Licht S. The ClpP N-terminus coordinates substrate access with protease active site reactivity. Biochemistry 2008, 47:11031-11040.
-
(2008)
Biochemistry
, vol.47
, pp. 11031-11040
-
-
Jennings, L.D.1
Bohon, J.2
Chance, M.R.3
Licht, S.4
-
99
-
-
0035122947
-
Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase
-
Kim Y.I., Levchenko I., Fraczkowska K., Woodruff R.V., Sauer R.T., Baker T.A. Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase. Nat. Struct. Biol. 2001, 8:230-233.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 230-233
-
-
Kim, Y.I.1
Levchenko, I.2
Fraczkowska, K.3
Woodruff, R.V.4
Sauer, R.T.5
Baker, T.A.6
-
100
-
-
0031961776
-
Versatile action of Escherichia coli ClpXP as protease or molecular chaperone for bacteriophage Mu transposition
-
Jones J.M., Welty D.J., Nakai H. Versatile action of Escherichia coli ClpXP as protease or molecular chaperone for bacteriophage Mu transposition. J. Biol. Chem. 1998, 273:459-465.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 459-465
-
-
Jones, J.M.1
Welty, D.J.2
Nakai, H.3
-
101
-
-
0037407940
-
Energy-dependent degradation: linkage between ClpXP-catalyzed nucleotide hydrolysis and protein-substrate processing
-
Burton R.E., Baker T.A., Sauer R.T. Energy-dependent degradation: linkage between ClpXP-catalyzed nucleotide hydrolysis and protein-substrate processing. Protein Sci. 2003, 12:893-902.
-
(2003)
Protein Sci.
, vol.12
, pp. 893-902
-
-
Burton, R.E.1
Baker, T.A.2
Sauer, R.T.3
-
102
-
-
79951707743
-
ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle
-
Smith D.M., Fraga H., Reis C., Kafri G., Goldberg A.L. ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle. Cell 2011, 144:526-538.
-
(2011)
Cell
, vol.144
, pp. 526-538
-
-
Smith, D.M.1
Fraga, H.2
Reis, C.3
Kafri, G.4
Goldberg, A.L.5
-
103
-
-
78651189765
-
On the nature of allosteric transitions: a plausible model
-
Monod J., Wyman J., Changeux J.P. On the nature of allosteric transitions: a plausible model. J. Mol. Biol. 1965, 12:88-118.
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
104
-
-
13444306170
-
Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing
-
Kenniston J.A., Baker T.A., Sauer R.T. Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:1390-1395.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 1390-1395
-
-
Kenniston, J.A.1
Baker, T.A.2
Sauer, R.T.3
-
105
-
-
67649550852
-
Polypeptide translocation by the AAA+ ClpXP protease machine
-
Barkow S.R., Levchenko I., Baker T.A., Sauer R.T. Polypeptide translocation by the AAA+ ClpXP protease machine. Chem. Biol. 2009, 16:605-612.
-
(2009)
Chem. Biol.
, vol.16
, pp. 605-612
-
-
Barkow, S.R.1
Levchenko, I.2
Baker, T.A.3
Sauer, R.T.4
-
106
-
-
0037143697
-
ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence
-
Hoskins J.R., Yanagihara K., Mizuuchi K., Wickner S. ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:11037-11042.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 11037-11042
-
-
Hoskins, J.R.1
Yanagihara, K.2
Mizuuchi, K.3
Wickner, S.4
-
107
-
-
38849103644
-
Protein unfolding by a AAA+ protease: critical dependence on ATP-hydrolysis rates and energy landscapes
-
Martin A., Baker T.A., Sauer R.T. Protein unfolding by a AAA+ protease: critical dependence on ATP-hydrolysis rates and energy landscapes. Nat. Struct. Mol. Biol. 2008, 15:139-145.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 139-145
-
-
Martin, A.1
Baker, T.A.2
Sauer, R.T.3
-
108
-
-
73349103814
-
Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease
-
Shin Y., Davis J.H., Brau R.R., Martin A., Kenniston J.A., Baker T.A., Sauer R.T., Lang M.J. Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:19340-19345.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 19340-19345
-
-
Shin, Y.1
Davis, J.H.2
Brau, R.R.3
Martin, A.4
Kenniston, J.A.5
Baker, T.A.6
Sauer, R.T.7
Lang, M.J.8
-
109
-
-
79955534260
-
ClpX(P) generates mechanical force to unfold and translocate its protein substrates
-
Maillard R.A., Chistol G., Sen M., Righini M., Tan J., Kaiser C.M., Hodges C., Martin A., Bustamante C. ClpX(P) generates mechanical force to unfold and translocate its protein substrates. Cell 2011, 145:459-469.
-
(2011)
Cell
, vol.145
, pp. 459-469
-
-
Maillard, R.A.1
Chistol, G.2
Sen, M.3
Righini, M.4
Tan, J.5
Kaiser, C.M.6
Hodges, C.7
Martin, A.8
Bustamante, C.9
-
110
-
-
0033598719
-
Structural distribution of stability in a thermophilic enzyme
-
Hollien J., Marqusee S. Structural distribution of stability in a thermophilic enzyme. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:13674-13678.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 13674-13678
-
-
Hollien, J.1
Marqusee, S.2
-
111
-
-
0033669185
-
Point mutations alter the mechanical stability of immunoglobulin modules
-
Li H., Carrion-Vasquez M., Oberhauser A.F., Marszalek P.E., Fernandez J.M. Point mutations alter the mechanical stability of immunoglobulin modules. Nat. Struct. Biol. 2000, 7:1117-1120.
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 1117-1120
-
-
Li, H.1
Carrion-Vasquez, M.2
Oberhauser, A.F.3
Marszalek, P.E.4
Fernandez, J.M.5
-
112
-
-
84855203478
-
Substrate denaturation and translocation by a proteolytic machine
-
Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, MA
-
J.A. Kenniston, Substrate denaturation and translocation by a proteolytic machine, Ph.D. thesis, Massachusetts Institute of Technology, Cambridge, MA (2005).
-
(2005)
-
-
Kenniston, J.A.1
-
113
-
-
5344269437
-
Sculpting the proteome with AAA+ proteases and disassembly machines
-
Sauer R.T., Bolon D.N., Burton B.M., Burton R.E., Flynn J.M., Grant R.A., Hersch G.L., Joshi S.A., Kenniston J.A., Levchenko I., Neher S.B., Oakes E.S.C., Siddiqui S.M., Wah D.A., Baker T.A. Sculpting the proteome with AAA+ proteases and disassembly machines. Cell 2004, 119:9-18.
-
(2004)
Cell
, vol.119
, pp. 9-18
-
-
Sauer, R.T.1
Bolon, D.N.2
Burton, B.M.3
Burton, R.E.4
Flynn, J.M.5
Grant, R.A.6
Hersch, G.L.7
Joshi, S.A.8
Kenniston, J.A.9
Levchenko, I.10
Neher, S.B.11
Oakes, E.S.C.12
Siddiqui, S.M.13
Wah, D.A.14
Baker, T.A.15
|