-
1
-
-
13044279382
-
-
Springer Verlag, New York
-
vanHolde, K.E. Chromatin (Springer Verlag, New York, 1988).
-
(1988)
Chromatin
-
-
vanHolde, K.E.1
-
2
-
-
0036532026
-
Histone modifications in transcriptional regulation
-
Berger, S.L. Histone modifications in transcriptional regulation. Curr. Opin. Genet. Dev. 12, 142-148 (2002).
-
(2002)
Curr. Opin. Genet. Dev
, vol.12
, pp. 142-148
-
-
Berger, S.L.1
-
3
-
-
15744396813
-
The key to development: Interpreting the histone code?
-
Margueron, R., Trojer, P. & Reinberg, D. The key to development: interpreting the histone code? Curr. Opin. Genet. Dev. 15, 163-176 (2005).
-
(2005)
Curr. Opin. Genet. Dev
, vol.15
, pp. 163-176
-
-
Margueron, R.1
Trojer, P.2
Reinberg, D.3
-
4
-
-
23044431656
-
Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin
-
Vakoc, C.R., Mandat, S.A., Olenchock, B.A. & Blobel, G.A. Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin. Mol. Cell 19, 381-391 (2005).
-
(2005)
Mol. Cell
, vol.19
, pp. 381-391
-
-
Vakoc, C.R.1
Mandat, S.A.2
Olenchock, B.A.3
Blobel, G.A.4
-
5
-
-
0037179716
-
Active genes are tri-methylated at K4 of histone H3
-
Santos-Rosa, H. et al. Active genes are tri-methylated at K4 of histone H3. Nature 419, 407-411 (2002).
-
(2002)
Nature
, vol.419
, pp. 407-411
-
-
Santos-Rosa, H.1
-
6
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B.E. et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-320 (2006).
-
(2006)
Cell
, vol.125
, pp. 315-320
-
-
Bernstein, B.E.1
-
7
-
-
9144260620
-
Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3
-
Lindroth, A.M. et al. Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3. EMBO J. 23, 4286-4296 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 4286-4296
-
-
Lindroth, A.M.1
-
8
-
-
0042671367
-
Cracking the histone code: One, two, three methyls, you're out!
-
Dutnall, R.N. Cracking the histone code: One, two, three methyls, you're out!. Mol. Cell 12, 3-4 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 3-4
-
-
Dutnall, R.N.1
-
9
-
-
0036850325
-
Cellular memory and the histone code
-
Turner, B.M. Cellular memory and the histone code. Cell 111, 285-291 (2002).
-
(2002)
Cell
, vol.111
, pp. 285-291
-
-
Turner, B.M.1
-
10
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl, B.D. & Allis, C.D. The language of covalent histone modifications. Nature 403, 41-45 (2000).
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
11
-
-
1442281449
-
Long-range histone acetylation at the Ifng gene is an essential feature of T ceell differentiation
-
Zhou, W., Chang, S. & Aune, T.M. Long-range histone acetylation at the Ifng gene is an essential feature of T ceell differentiation. Proc. Natl. Acad. Sci. USA 101, 2440-2445 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2440-2445
-
-
Zhou, W.1
Chang, S.2
Aune, T.M.3
-
12
-
-
28044433631
-
Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells
-
Chang, S. & Aune, T.M. Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells. Proc. Natl. Acad. Sci. USA 102, 17095-17100 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17095-17100
-
-
Chang, S.1
Aune, T.M.2
-
13
-
-
0034687789
-
Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain
-
Forsberg, E.C. et al. Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain. Proc. Natl. Acad. Sci. USA 97, 14494-14499 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14494-14499
-
-
Forsberg, E.C.1
-
14
-
-
2442464995
-
Dynamic assembly of silent chromatin during thymocyte maturation
-
Su, R.C. et al. Dynamic assembly of silent chromatin during thymocyte maturation. Nat. Genet. 36, 502-506 (2004).
-
(2004)
Nat. Genet
, vol.36
, pp. 502-506
-
-
Su, R.C.1
-
15
-
-
33750732646
-
Long-range histone acetylation: Biological significance, structural implications, and mechanisms
-
Calestagne-Morelli, A. & Ausio, J. Long-range histone acetylation: biological significance, structural implications, and mechanisms. Biochem. Cell Biol. 84, 518-527 (2006).
-
(2006)
Biochem. Cell Biol
, vol.84
, pp. 518-527
-
-
Calestagne-Morelli, A.1
Ausio, J.2
-
16
-
-
33746600716
-
Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins
-
Papp, B. & Muller, J. Histone trimethylation and the maintenance of transcriptional ON and OFF states by trxG and PcG proteins. Genes Dev. 20, 2041-2054 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 2041-2054
-
-
Papp, B.1
Muller, J.2
-
17
-
-
0346458664
-
Dynamic alterations in the conformation of the Ifng gene region during T helper cell differentiation
-
Eivazova, E.R. & Aune, T.M. Dynamic alterations in the conformation of the Ifng gene region during T helper cell differentiation. Proc. Natl. Acad. Sci. USA 101, 251-256 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 251-256
-
-
Eivazova, E.R.1
Aune, T.M.2
-
18
-
-
33749060536
-
Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene
-
Kahn, T.G., Schwartz, Y.B., Dellino, G.I. & Pirrotta, V. Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene. J. Biol. Chem. 281, 29064-29075 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 29064-29075
-
-
Kahn, T.G.1
Schwartz, Y.B.2
Dellino, G.I.3
Pirrotta, V.4
-
19
-
-
0034814993
-
Histone acetylation beyond promoters: Long-range acelylation patterns in the chromatin world
-
Forsberg, E.C. & Bresnick, E.H. Histone acetylation beyond promoters: long-range acelylation patterns in the chromatin world. Bioessays 23, 820-830 (2001).
-
(2001)
Bioessays
, vol.23
, pp. 820-830
-
-
Forsberg, E.C.1
Bresnick, E.H.2
-
20
-
-
0038638583
-
An epigenetic view of helper T cell differentiation
-
Ansel, K.M., Lee, D.U. & Rao, A. An epigenetic view of helper T cell differentiation. Nat. Immunol. 4, 616-623 (2003).
-
(2003)
Nat. Immunol
, vol.4
, pp. 616-623
-
-
Ansel, K.M.1
Lee, D.U.2
Rao, A.3
-
21
-
-
33646012294
-
T helper cell differentiation: Regulation by cis elements and epigenetics
-
Lee, G.R., Kim, S.T., Spilianakis, C.G., Fields, P.E. & Flavell, R.A. T helper cell differentiation: Regulation by cis elements and epigenetics. Immunity 24, 369-379 (2006).
-
(2006)
Immunity
, vol.24
, pp. 369-379
-
-
Lee, G.R.1
Kim, S.T.2
Spilianakis, C.G.3
Fields, P.E.4
Flavell, R.A.5
-
22
-
-
0038195719
-
Molecular mechanisms regulating Th1 immune responses
-
Szabo, S.J., Sullivan, B.M., Peng, S.L. & Glimcher, L.H. Molecular mechanisms regulating Th1 immune responses. Annu. Rev. Immunol. 21, 713-758 (2003).
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 713-758
-
-
Szabo, S.J.1
Sullivan, B.M.2
Peng, S.L.3
Glimcher, L.H.4
-
23
-
-
33644646837
-
Chromatin structure and gene regulation in T cell development and function
-
Wilson, C.B. & Merkenschlager, M. Chromatin structure and gene regulation in T cell development and function. Curr. Opin. Immunol. 18, 143-151 (2006).
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 143-151
-
-
Wilson, C.B.1
Merkenschlager, M.2
-
24
-
-
0035070195
-
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
-
Grogan, J.L. et al. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity 14, 205-215 (2001).
-
(2001)
Immunity
, vol.14
, pp. 205-215
-
-
Grogan, J.L.1
-
25
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S.J. et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100, 655-669 (2000).
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
26
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng, W. & Flavell, R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89, 587-596 (1997).
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
27
-
-
15844396183
-
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder, W.E. et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 382, 171-174 (1996).
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
-
28
-
-
0036305450
-
H cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
H cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol. 3, 643-651 (2002).
-
(2002)
Nat Immunol
, vol.3
, pp. 643-651
-
-
Avni, O.1
-
29
-
-
0032412441
-
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
-
Agarwal, S. & Rao, A. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9, 765-775 (1998).
-
(1998)
Immunity
, vol.9
, pp. 765-775
-
-
Agarwal, S.1
Rao, A.2
-
30
-
-
3843060051
-
Chromatin landscape dynamics of the II4-II13 locus during T helper 1 and 2 development
-
Baguet, A. & Bix, M. Chromatin landscape dynamics of the II4-II13 locus during T helper 1 and 2 development. Proc. Natl. Acad. Sci. USA 101, 11410-11415 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11410-11415
-
-
Baguet, A.1
Bix, M.2
-
31
-
-
0036830465
-
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
-
Yamashita, M. et al. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J. Biol. Chem. 277, 42399-42408 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 42399-42408
-
-
Yamashita, M.1
-
32
-
-
0037100265
-
Cutting edge: Changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation
-
Fields, P.E., Kim, S.T. & Flavell, R.A. Cutting edge: Changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation. J. Immunol. 169, 647-650 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 647-650
-
-
Fields, P.E.1
Kim, S.T.2
Flavell, R.A.3
-
33
-
-
33749352265
-
Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27
-
Schubert, D. et al. Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27. EMBO J. 25, 4638-4649 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 4638-4649
-
-
Schubert, D.1
-
34
-
-
33749054895
-
Architecture of a polycomb nucleoprotein complex
-
Mohd-Sarip, A. et al. Architecture of a polycomb nucleoprotein complex. Mol. Cell 24, 91-100 (2006).
-
(2006)
Mol. Cell
, vol.24
, pp. 91-100
-
-
Mohd-Sarip, A.1
-
35
-
-
8844219674
-
Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes
-
Ringrose, L., Ehret, H. & Paro, R. Distinct contributions of histone H3 lysine 9 and 27 methylation to locus-specific stability of polycomb complexes. Mol. Cell 16, 641-653 (2004).
-
(2004)
Mol. Cell
, vol.16
, pp. 641-653
-
-
Ringrose, L.1
Ehret, H.2
Paro, R.3
-
36
-
-
0030034795
-
Hidden Markov Model approach to variation among sites in rate of evolution
-
Felsenstein, J. & Churchill, G.A. A Hidden Markov Model approach to variation among sites in rate of evolution. Mol. Biol. Evol. 13 93-104 (1996).
-
(1996)
Mol. Biol. Evol
, vol.13
, pp. 93-104
-
-
Felsenstein, J.1
Churchill, G.A.A.2
-
37
-
-
23744458086
-
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
-
Siepel, A. et al. Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 15, 1034-1050 (2005).
-
(2005)
Genome Res
, vol.15
, pp. 1034-1050
-
-
Siepel, A.1
-
38
-
-
0029739627
-
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
-
Xu, X., Sun, Y.L. & Hoey, T. Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain. Science 273, 794-797 (1996).
-
(1996)
Science
, vol.273
, pp. 794-797
-
-
Xu, X.1
Sun, Y.L.2
Hoey, T.3
-
39
-
-
0030922630
-
Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres
-
Laible, G. et al. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres. EMBO J. 16, 3219-3232 (1997).
-
(1997)
EMBO J
, vol.16
, pp. 3219-3232
-
-
Laible, G.1
-
40
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose, L. & Paro, R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu. Rev. Genet. 38, 413-443 (2004).
-
(2004)
Annu. Rev. Genet
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
41
-
-
0034905085
-
Regulation of transcription factor YY1 by acetylation and deacetylation
-
Yao, Y.L., Yang, W.M. & Seto, E. Regulation of transcription factor YY1 by acetylation and deacetylation. Mol. Cell. Biol. 21, 5979-5991 (2001).
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 5979-5991
-
-
Yao, Y.L.1
Yang, W.M.2
Seto, E.3
-
42
-
-
7544230144
-
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
-
Caretti, G., Di Padova, M., Micales, B., Lyons, G.E. & Sartorelli, V. The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev. 18, 2627-2638 (2004).
-
(2004)
Genes Dev
, vol.18
, pp. 2627-2638
-
-
Caretti, G.1
Di Padova, M.2
Micales, B.3
Lyons, G.E.4
Sartorelli, V.5
-
43
-
-
0037108597
-
A minimal IFN-gamma promoter confers Th1 selective expression
-
Soutto, M. et al. A minimal IFN-gamma promoter confers Th1 selective expression. J. Immunol. 169, 4205-4212 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 4205-4212
-
-
Soutto, M.1
-
44
-
-
0029740336
-
The nuclear factor YY1 suppresses the human γ interferon promoter through two mechanisms: Inhibition of AP1 binding and activation of a silencer element
-
Ye, J., Cippitelli, M., Dorman, L., Ortaldo, J.R. & Young, H.A. The nuclear factor YY1 suppresses the human γ interferon promoter through two mechanisms: Inhibition of AP1 binding and activation of a silencer element. Mol. Cell. Biol. 16, 4744-4753 (1996).
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 4744-4753
-
-
Ye, J.1
Cippitelli, M.2
Dorman, L.3
Ortaldo, J.R.4
Young, H.A.5
-
45
-
-
33645065358
-
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
-
Usui, T. et al. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J. Exp. Med. 203, 755-766 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 755-766
-
-
Usui, T.1
-
46
-
-
12344269852
-
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
-
Hwang, E.S., Szabo, SJ., Schwartzberg, P.L. & Glimcher, L.H. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science 307, 430-433 (2005).
-
(2005)
Science
, vol.307
, pp. 430-433
-
-
Hwang, E.S.1
Szabo, S.J.2
Schwartzberg, P.L.3
Glimcher, L.H.4
-
47
-
-
24744462507
-
EZH2 and histone 3 trimethyl lysine 27 associated with II4 and II13 gene silencing in Th1 cells
-
Koyanagi, M. et al. EZH2 and histone 3 trimethyl lysine 27 associated with II4 and II13 gene silencing in Th1 cells. J. Biol. Chem. 280, 31470-31477 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 31470-31477
-
-
Koyanagi, M.1
-
48
-
-
13144295005
-
Conserved non-genic sequences - an unexpected feature of mammalian genomes
-
Dermitzakis, E.T., Raymond, A. & Antonarakis, S.E. Conserved non-genic sequences - an unexpected feature of mammalian genomes. Nat. Rev. Genet. 6, 151-157 (2005).
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 151-157
-
-
Dermitzakis, E.T.1
Raymond, A.2
Antonarakis, S.E.3
-
49
-
-
33846208370
-
A distal conserved sequence element controls Ifng gene expression by T cells and NK cells
-
Hatton, R.D. et al. A distal conserved sequence element controls Ifng gene expression by T cells and NK cells. Immunity 25 717-729 (2006).
-
(2006)
Immunity
, vol.25
, pp. 717-729
-
-
Hatton, R.D.1
-
50
-
-
14044276321
-
Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression
-
Rodriguez-Galan, M.C., Bream, J.H., Farr, A. & Young, H.A. Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression. J. Immunol. 174, 2796-2804 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 2796-2804
-
-
Rodriguez-Galan, M.C.1
Bream, J.H.2
Farr, A.3
Young, H.A.4
-
51
-
-
1042278131
-
A distal enhancer in the interferon-γ (IFN-γ) locus revealed by genome sequence comparison
-
Lee, D.U., Avni, O., Chen, L. & Rao, A. A distal enhancer in the interferon-γ (IFN-γ) locus revealed by genome sequence comparison. J. Biol. Chem. 279, 4802-4810 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 4802-4810
-
-
Lee, D.U.1
Avni, O.2
Chen, L.3
Rao, A.4
-
52
-
-
4344574045
-
Evolutionarily conserved sequence elements that positively regulate IFN-γ expression in T cells
-
Shnyreva, M. et al. Evolutionarily conserved sequence elements that positively regulate IFN-γ expression in T cells. Proc. Natl. Acad. Sci. USA 101, 12622-12627 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12622-12627
-
-
Shnyreva, M.1
-
53
-
-
0037114123
-
Cutting edge: Distal regulatory elements are required to achieve selective expression of IFN-γ in Th1/ Tc1 effector cells
-
Soutto, M., Zhou, W. & Aune, T.M. Cutting edge: Distal regulatory elements are required to achieve selective expression of IFN-γ in Th1/ Tc1 effector cells. J. Immunol. 169, 6664-6667 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 6664-6667
-
-
Soutto, M.1
Zhou, W.2
Aune, T.M.3
-
54
-
-
0032212793
-
Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
-
Ouyang, W. et al. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 9, 745-755 (1998).
-
(1998)
Immunity
, vol.9
, pp. 745-755
-
-
Ouyang, W.1
|