Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity

Molecular Genetics and Metabolism

Volumn 108, Issue 1, 2013, Pages 56-64

  Yap, Thai Leong ^a   Velayati, Arash ^b   Sidransky, Ellen ^b   Lee, Jennifer C ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

Fluorescence; Gaucher disease; Parkinson disease; Protein lipid interactions

Indexed keywords

ALPHA SYNUCLEIN; GLUCOSYLCERAMIDASE;

ALPHA HELIX; ARTICLE; CELL VACUOLE; COMPLEX FORMATION; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME ACTIVITY; FLUORESCENCE; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ALPHA-SYNUCLEIN; AMINO ACID SEQUENCE; CELL MEMBRANE; CIRCULAR DICHROISM; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; GLUCOSYLCERAMIDASE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, FLUORESCENCE;

EID: 84871720426     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2012.11.010     Document Type: Article

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