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Volumn 50, Issue 12, 2011, Pages 1963-1965

Residue-specific fluorescent probes of α-synuclein: Detection of early events at the N- and C-termini during fibril assembly

Author keywords

[No Author keywords available]

Indexed keywords

ASSEMBLY PROCESS; CONFORMATIONAL CHANGE; ENVIRONMENTALLY SENSITIVE; FLUORESCENT PROBES; KINETIC BEHAVIOR; PARKINSON'S DISEASE; SPECTROSCOPIC PROPERTY; SYNUCLEIN;

EID: 79952932859     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2000824     Document Type: Article
Times cited : (29)

References (39)
  • 5
    • 70349249705 scopus 로고    scopus 로고
    • Tompa, P. (2009) FEBS J. 276, 5406-5415
    • (2009) FEBS J. , vol.276 , pp. 5406-5415
    • Tompa, P.1
  • 30
    • 84855628930 scopus 로고    scopus 로고
    • We estimate the aggregation yield to be 80-90%, as assessed by UV spectroscopic analysis of the remaining soluble protein. While the absolute amount of β-sheet-containing fibrils is difficult to determine, we find comparable CD spectroscopic signals (217-218 nm) as in previous work. (21)
    • We estimate the aggregation yield to be 80-90%, as assessed by UV spectroscopic analysis of the remaining soluble protein. While the absolute amount of β-sheet-containing fibrils is difficult to determine, we find comparable CD spectroscopic signals (217-218 nm) as in previous work. (21)
  • 34
    • 79952919816 scopus 로고    scopus 로고
    • Using similar analysis of the human islet amyloid polypeptide implicated in type 2 diabetes, the inner core residues exhibited the earliest transitions while changes at residues on the N- and C-termini occurred later. (33)
    • Using similar analysis of the human islet amyloid polypeptide implicated in type 2 diabetes, the inner core residues exhibited the earliest transitions while changes at residues on the N- and C-termini occurred later. (33)
  • 39
    • 79952925635 scopus 로고    scopus 로고
    • note
    • scaled(Δ〈λ〉 ) of 0.45(2) for Dns7.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.