Characterization of recombinant wild type and site-directed mutations of apolipoprotein C-III: Lipid binding, displacement of ApoE, and inhibition of lipoprotein lipase

Biochemistry

Volumn 39, Issue 31, 2000, Pages 9201-9212

  Liu, Haiqun ^a   Talmud, Philippa J ^a   Lins, Laurence ^b   Brasseur, Robert ^c   Olivecrona, Gunilla ^e   Peelman, Frank ^d   Vandekerckhove, Joël ^d   Rosseneu, Maryvonne ^d   Labeur, Christine ^d  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b INSERM   (France)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

^e UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN C; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; DIPALMITOYLPHOSPHATIDYLCHOLINE; ENZYME INHIBITOR; LIPOPROTEIN LIPASE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; BIOSYNTHESIS; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; GEL CHROMATOGRAPHY; GENE VECTOR; GENETIC VARIABILITY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LIPID METABOLISM; METABOLISM; MOLECULAR GENETICS; PHYSICAL CHEMISTRY; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; AMINO ACID SEQUENCE; ANIMALS; APOLIPOPROTEIN C-III; APOLIPOPROTEINS C; APOLIPOPROTEINS E; BINDING SITES; CATTLE; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, GEL; ENZYME INHIBITORS; GENETIC VECTORS; HUMANS; LIPID METABOLISM; LIPOPROTEIN LIPASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; VARIATION (GENETICS);

EID: 0034622437     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0009441     Document Type: Article

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