메뉴 건너뛰기




Volumn 273, Issue 1, 2013, Pages 6-30

Lipoprotein(a): Resurrected by genetics

Author keywords

Apolipoprotein(a); Copy number variation; Coronary heart disease; Lipoprotein(a); Mendelian randomization; Quantitative genetic trait

Indexed keywords

APOLIPOPROTEIN B; ESTROGEN; GROWTH HORMONE; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; THYROID HORMONE;

EID: 84871674237     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2012.02592.x     Document Type: Article
Times cited : (390)

References (202)
  • 1
    • 47649091099 scopus 로고
    • A new serum type system in man - the Lp system
    • Berg K. A new serum type system in man - the Lp system. Acta Path Microbiol Scand 1963; 59: 369-82.
    • (1963) Acta Path Microbiol Scand , vol.59 , pp. 369-382
    • Berg, K.1
  • 2
    • 0024362630 scopus 로고
    • The mysteries of lipoprotein(a)
    • Utermann G. The mysteries of lipoprotein(a). Science 1989; 246: 904-10.
    • (1989) Science , vol.246 , pp. 904-910
    • Utermann, G.1
  • 3
    • 0025769197 scopus 로고
    • Lipoprotein (a) and coronary heart disease risk: a nested case-control study of the Helsinki Heart Study participants
    • Jauhiainen M, Koskinen P, Ehnholm C et al. Lipoprotein (a) and coronary heart disease risk: a nested case-control study of the Helsinki Heart Study participants. Atherosclerosis 1991; 89: 59-67.
    • (1991) Atherosclerosis , vol.89 , pp. 59-67
    • Jauhiainen, M.1    Koskinen, P.2    Ehnholm, C.3
  • 4
    • 0027366185 scopus 로고
    • A prospective study of lipoprotein(a) and the risk of myocardial infarction
    • Ridker PM, Hennekens CH, Stampfer MJ. A prospective study of lipoprotein(a) and the risk of myocardial infarction. JAMA 1993; 270: 2195-9.
    • (1993) JAMA , vol.270 , pp. 2195-2199
    • Ridker, P.M.1    Hennekens, C.H.2    Stampfer, M.J.3
  • 5
    • 67651210632 scopus 로고    scopus 로고
    • Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality
    • Erqou S, Kaptoge S, Perry PL et al. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA 2009; 302: 412-23.
    • (2009) JAMA , vol.302 , pp. 412-423
    • Erqou, S.1    Kaptoge, S.2    Perry, P.L.3
  • 6
    • 77951637599 scopus 로고    scopus 로고
    • Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants
    • Erqou S, Thompson A, Di AE et al. Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58, 000 participants. J Am Coll Cardiol 2010; 55: 2160-7.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2160-2167
    • Erqou, S.1    Thompson, A.2    Di, A.E.3
  • 7
    • 67049167090 scopus 로고    scopus 로고
    • Genetically elevated lipoprotein(a) and increased risk of myocardial infarction
    • Kamstrup PR, Tybjaerg-Hansen A, Steffensen R, Nordestgaard BG. Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. JAMA 2009; 301: 2331-9.
    • (2009) JAMA , vol.301 , pp. 2331-2339
    • Kamstrup, P.R.1    Tybjaerg-Hansen, A.2    Steffensen, R.3    Nordestgaard, B.G.4
  • 8
    • 61349137526 scopus 로고    scopus 로고
    • Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
    • Trégouët DA, Konig IR, Erdmann J et al. Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet 2009; 41: 283-5.
    • (2009) Nat Genet , vol.41 , pp. 283-285
    • Trégouët, D.A.1    Konig, I.R.2    Erdmann, J.3
  • 9
    • 73549097512 scopus 로고    scopus 로고
    • Genetic variants associated with Lp(a) lipoprotein level and coronary disease
    • Clarke R, Peden JF, Hopewell JC et al. Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med 2009; 361: 2518-28.
    • (2009) N Engl J Med , vol.361 , pp. 2518-2528
    • Clarke, R.1    Peden, J.F.2    Hopewell, J.C.3
  • 10
    • 78649888517 scopus 로고    scopus 로고
    • Lipoprotein(a) as a cardiovascular risk factor: current status
    • Nordestgaard BG, Chapman MJ, Ray K et al. Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J 2010; 31: 2844-53.
    • (2010) Eur Heart J , vol.31 , pp. 2844-2853
    • Nordestgaard, B.G.1    Chapman, M.J.2    Ray, K.3
  • 11
    • 0023636242 scopus 로고
    • cDNA sequence of human apolipoprotein(a) is homologous to plasminogen
    • McLean JW, Tomlinson JE, Kuang W-J et al. cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature 1987; 330: 132-7.
    • (1987) Nature , vol.330 , pp. 132-137
    • McLean, J.W.1    Tomlinson, J.E.2    Kuang, W.-J.3
  • 12
    • 0030666211 scopus 로고    scopus 로고
    • Convergent evolution of apolipoprotein(a) in primates and hedgehog
    • Lawn RM, Schwartz K, Patthy L. Convergent evolution of apolipoprotein(a) in primates and hedgehog. Proc Natl Acad Sci USA 1997; 94: 11992-7.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11992-11997
    • Lawn, R.M.1    Schwartz, K.2    Patthy, L.3
  • 13
    • 0024536171 scopus 로고
    • Rhesus monkey apolipoprotein(a). Sequence, evolution, and sites of synthesis
    • Tomlinson JE, McLean JW, Lawn RM. Rhesus monkey apolipoprotein(a). Sequence, evolution, and sites of synthesis. J Biol Chem 1989; 264: 5957-65.
    • (1989) J Biol Chem , vol.264 , pp. 5957-5965
    • Tomlinson, J.E.1    McLean, J.W.2    Lawn, R.M.3
  • 14
    • 0026048441 scopus 로고
    • Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis
    • Lackner C, Boerwinkle E, Leffert CC, Rahmig T, Hobbs HH. Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis. J Clin Invest 1991; 87: 2153-61.
    • (1991) J Clin Invest , vol.87 , pp. 2153-2161
    • Lackner, C.1    Boerwinkle, E.2    Leffert, C.C.3    Rahmig, T.4    Hobbs, H.H.5
  • 15
    • 0026526357 scopus 로고
    • The apolipoprotein(a) gene: a transcribed hypervariable locus controlling plasma lipoprotein(a) concentration
    • Kraft HG, Köchl S, Menzel HJ, Sandholzer C, Utermann G. The apolipoprotein(a) gene: a transcribed hypervariable locus controlling plasma lipoprotein(a) concentration. Hum Genet 1992; 90: 220-30.
    • (1992) Hum Genet , vol.90 , pp. 220-230
    • Kraft, H.G.1    Köchl, S.2    Menzel, H.J.3    Sandholzer, C.4    Utermann, G.5
  • 16
    • 0032899412 scopus 로고    scopus 로고
    • Counting the repetitive kringle-IV repeats in the gene encoding human apolipoprotein(a) by fibre-FISH [letter]
    • Erdel M, Hubalek M, Lingenhel A, Kofler K, Duba HC, Utermann G. Counting the repetitive kringle-IV repeats in the gene encoding human apolipoprotein(a) by fibre-FISH [letter]. Nat Genet 1999; 21: 357-8.
    • (1999) Nat Genet , vol.21 , pp. 357-358
    • Erdel, M.1    Hubalek, M.2    Lingenhel, A.3    Kofler, K.4    Duba, H.C.5    Utermann, G.6
  • 17
    • 0025060734 scopus 로고
    • Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA
    • Koschinsky ML, Beisiegel U, Henne-Bruns D, Eaton DL, Lawn RM. Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA. Biochemistry 1990; 29: 640-4.
    • (1990) Biochemistry , vol.29 , pp. 640-644
    • Koschinsky, M.L.1    Beisiegel, U.2    Henne-Bruns, D.3    Eaton, D.L.4    Lawn, R.M.5
  • 18
    • 0028920022 scopus 로고
    • Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma
    • Mooser V, Mancini FP, Bopp S et al. Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma. Hum Mol Genet 1995; 4: 173-81.
    • (1995) Hum Mol Genet , vol.4 , pp. 173-181
    • Mooser, V.1    Mancini, F.P.2    Bopp, S.3
  • 19
    • 0035933848 scopus 로고    scopus 로고
    • Functional analysis of the chimpanzee and human apo(a) promoter sequences: identification of sequence variations responsible for elevated transcriptional activity in chimpanzee
    • Huby T, Dachet C, Lawn RM, Wickings J, Chapman MJ, Thillet J. Functional analysis of the chimpanzee and human apo(a) promoter sequences: identification of sequence variations responsible for elevated transcriptional activity in chimpanzee. J Biol Chem 2001; 276: 22209-14.
    • (2001) J Biol Chem , vol.276 , pp. 22209-22214
    • Huby, T.1    Dachet, C.2    Lawn, R.M.3    Wickings, J.4    Chapman, M.J.5    Thillet, J.6
  • 20
    • 0028181875 scopus 로고
    • Lipoprotein[a] in the chimpanzee - relationship of Apo[a] phenotype to elevated plasma Lp[a] levels
    • Doucet C, Huby T, Chapman J, Thillet J. Lipoprotein[a] in the chimpanzee - relationship of Apo[a] phenotype to elevated plasma Lp[a] levels. J Lipid Res 1994; 35: 263-70.
    • (1994) J Lipid Res , vol.35 , pp. 263-270
    • Doucet, C.1    Huby, T.2    Chapman, J.3    Thillet, J.4
  • 21
    • 0002697048 scopus 로고    scopus 로고
    • Lipoprotein(a)
    • In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. . New York: McGraw-Hill
    • Utermann G. Lipoprotein(a). In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic & Molecular Bases of Inherited Disease. New York: McGraw-Hill, 2000; 2753-87.
    • (2000) The Metabolic & Molecular Bases of Inherited Disease , pp. 2753-2787
    • Utermann, G.1
  • 23
    • 80052380574 scopus 로고    scopus 로고
    • Farnesoid X receptor represses hepatic human APOA gene expression
    • Chennamsetty I, Claudel T, Kostner KM et al. Farnesoid X receptor represses hepatic human APOA gene expression. J Clin Invest 2011; 121: 3724-34.
    • (2011) J Clin Invest , vol.121 , pp. 3724-3734
    • Chennamsetty, I.1    Claudel, T.2    Kostner, K.M.3
  • 24
    • 0024529337 scopus 로고
    • Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis
    • Kraft HG, Menzel HJ, Hoppichler F, Vogel W, Utermann G. Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis. J Clin Invest 1989; 83: 137-42.
    • (1989) J Clin Invest , vol.83 , pp. 137-142
    • Kraft, H.G.1    Menzel, H.J.2    Hoppichler, F.3    Vogel, W.4    Utermann, G.5
  • 25
    • 0032816599 scopus 로고    scopus 로고
    • The seventh myth of lipoprotein(a): where and how is it assembled?
    • Dieplinger H, Utermann G. The seventh myth of lipoprotein(a): where and how is it assembled? Curr Opin Lipidol 1999; 10: 275-83.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 275-283
    • Dieplinger, H.1    Utermann, G.2
  • 26
    • 1842609781 scopus 로고    scopus 로고
    • Structure-function relationships in apolipoprotein(a): insights into lipoprotein(a) assembly and pathogenicity
    • Koschinsky ML, Marcovina SM. Structure-function relationships in apolipoprotein(a): insights into lipoprotein(a) assembly and pathogenicity. Curr Opin Lipidol 2004; 15: 167-74.
    • (2004) Curr Opin Lipidol , vol.15 , pp. 167-174
    • Koschinsky, M.L.1    Marcovina, S.M.2
  • 27
    • 0028116176 scopus 로고
    • Cell surface assembly of lipoprotein(a) in primary cultures of baboon hepatocytes
    • White AL, Lanford RE. Cell surface assembly of lipoprotein(a) in primary cultures of baboon hepatocytes. J Biol Chem 1994; 269: 28716-23.
    • (1994) J Biol Chem , vol.269 , pp. 28716-28723
    • White, A.L.1    Lanford, R.E.2
  • 28
    • 33747505832 scopus 로고    scopus 로고
    • Catalysis of covalent Lp(a) assembly: evidence for an extracellular enzyme activity that enhances disulfide bond formation
    • Becker L, Nesheim ME, Koschinsky ML. Catalysis of covalent Lp(a) assembly: evidence for an extracellular enzyme activity that enhances disulfide bond formation. Biochemistry 2006; 45: 9919-28.
    • (2006) Biochemistry , vol.45 , pp. 9919-9928
    • Becker, L.1    Nesheim, M.E.2    Koschinsky, M.L.3
  • 29
    • 0028922301 scopus 로고
    • Biosynthesis and metabolism of lipoprotein(a)
    • White AL, Lanford RE. Biosynthesis and metabolism of lipoprotein(a). Curr Opin Lipidol 1995; 6: 75-80.
    • (1995) Curr Opin Lipidol , vol.6 , pp. 75-80
    • White, A.L.1    Lanford, R.E.2
  • 30
    • 0032816711 scopus 로고    scopus 로고
    • Lipoprotein(a): intrigues and insights
    • Hobbs HH, White AL. Lipoprotein(a): intrigues and insights. Curr Opin Lipidol 1999; 10: 225-36.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 225-236
    • Hobbs, H.H.1    White, A.L.2
  • 31
    • 0029731350 scopus 로고    scopus 로고
    • The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells
    • Brunner C, Lobentanz EM, Pethö-Schramm A et al. The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells. J Biol Chem 1996; 271: 32403-10.
    • (1996) J Biol Chem , vol.271 , pp. 32403-32410
    • Brunner, C.1    Lobentanz, E.M.2    Pethö-Schramm, A.3
  • 32
    • 0031046798 scopus 로고    scopus 로고
    • Influence of allelic variation on apolipoprotein(a) folding in the endoplasmic reticulum
    • White AL, Guerra B, Lanford RE. Influence of allelic variation on apolipoprotein(a) folding in the endoplasmic reticulum. J Biol Chem 1997; 272: 5048-55.
    • (1997) J Biol Chem , vol.272 , pp. 5048-5055
    • White, A.L.1    Guerra, B.2    Lanford, R.E.3
  • 33
    • 0027477975 scopus 로고
    • Intracellular maturation of apolipoprotein[a] and assembly of lipoprotein[a] in primary baboon hepatocytes
    • White AL, Rainwater DL, Lanford RE. Intracellular maturation of apolipoprotein[a] and assembly of lipoprotein[a] in primary baboon hepatocytes. J Lipid Res 1993; 34: 509-17.
    • (1993) J Lipid Res , vol.34 , pp. 509-517
    • White, A.L.1    Rainwater, D.L.2    Lanford, R.E.3
  • 34
    • 77949485460 scopus 로고    scopus 로고
    • Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
    • Raal FJ, Santos RD, Blom DJ et al. Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial. Lancet 2010; 375: 998-1006.
    • (2010) Lancet , vol.375 , pp. 998-1006
    • Raal, F.J.1    Santos, R.D.2    Blom, D.J.3
  • 36
    • 48349088178 scopus 로고    scopus 로고
    • Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
    • Samaha FF, McKenney J, Bloedon LT, Sasiela WJ, Rader DJ. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat Clin Pract Cardiovasc Med 2008; 5: 497-505.
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 497-505
    • Samaha, F.F.1    McKenney, J.2    Bloedon, L.T.3    Sasiela, W.J.4    Rader, D.J.5
  • 37
    • 0025098439 scopus 로고
    • Abetalipoproteinemia with an apoB-100-lipoprotein(a) glycoprotein complex in plasma: indication for an assembly defect
    • Menzel H-J, Dieplinger H, Lackner C et al. Abetalipoproteinemia with an apoB-100-lipoprotein(a) glycoprotein complex in plasma: indication for an assembly defect. J Biol Chem 1990; 265: 981-6.
    • (1990) J Biol Chem , vol.265 , pp. 981-986
    • Menzel, H.-J.1    Dieplinger, H.2    Lackner, C.3
  • 39
    • 0028245313 scopus 로고
    • The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate
    • Rader DJ, Cain W, Ikewaki K et al. The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate. J Clin Invest 1994; 93: 2758-63.
    • (1994) J Clin Invest , vol.93 , pp. 2758-2763
    • Rader, D.J.1    Cain, W.2    Ikewaki, K.3
  • 40
    • 0032975165 scopus 로고    scopus 로고
    • Identification of Megalin/gp330 as a receptor for lipoprotein(a) in vitro
    • Niemeier A, Willnow T, Dieplinger H et al. Identification of Megalin/gp330 as a receptor for lipoprotein(a) in vitro. Arterioscler Thromb Vasc Biol 1999; 19: 552-61.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 552-561
    • Niemeier, A.1    Willnow, T.2    Dieplinger, H.3
  • 41
    • 0020624873 scopus 로고
    • Studies on the role of specific cell surface receptors in the removal of lipoprotein(a) in man
    • Krempler F, Kostner GM, Roscher A, Haslauer F, Bolzano K, Sandhofer F. Studies on the role of specific cell surface receptors in the removal of lipoprotein(a) in man. J Clin Invest 1983; 71: 1431-41.
    • (1983) J Clin Invest , vol.71 , pp. 1431-1441
    • Krempler, F.1    Kostner, G.M.2    Roscher, A.3    Haslauer, F.4    Bolzano, K.5    Sandhofer, F.6
  • 42
    • 0031456893 scopus 로고    scopus 로고
    • LDL-mediated interaction of Lp[a] with HepG2 cells: a novel fluorescence microscopy approach
    • Hofer G, Steyrer E, Kostner GM, Hermetter A. LDL-mediated interaction of Lp[a] with HepG2 cells: a novel fluorescence microscopy approach. J Lipid Res 1997; 38: 2411-21.
    • (1997) J Lipid Res , vol.38 , pp. 2411-2421
    • Hofer, G.1    Steyrer, E.2    Kostner, G.M.3    Hermetter, A.4
  • 43
    • 2442497725 scopus 로고
    • Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis
    • Utermann G, Hoppichler F, Dieplinger H, Seed M, Thompson G, Boerwinkle E. Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis. Proc Natl Acad Sci USA 1989; 86: 4171-4.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4171-4174
    • Utermann, G.1    Hoppichler, F.2    Dieplinger, H.3    Seed, M.4    Thompson, G.5    Boerwinkle, E.6
  • 44
    • 15644361814 scopus 로고    scopus 로고
    • Renovascular arteriovenous differences in Lp(a) plasma concentrations suggest removal of Lp(a) from the renal circulation
    • Kronenberg F, Trenkwalder E, Lingenhel A et al. Renovascular arteriovenous differences in Lp(a) plasma concentrations suggest removal of Lp(a) from the renal circulation. J Lipid Res 1997; 38: 1755-63.
    • (1997) J Lipid Res , vol.38 , pp. 1755-1763
    • Kronenberg, F.1    Trenkwalder, E.2    Lingenhel, A.3
  • 45
    • 0029832040 scopus 로고    scopus 로고
    • Kringle-containing fragments of apolipoprotein(a) circulate in human plasma and are excreted into the urine
    • Mooser V, Marcovina SM, White AL, Hobbs HH. Kringle-containing fragments of apolipoprotein(a) circulate in human plasma and are excreted into the urine. J Clin Invest 1996; 98: 2414-24.
    • (1996) J Clin Invest , vol.98 , pp. 2414-2424
    • Mooser, V.1    Marcovina, S.M.2    White, A.L.3    Hobbs, H.H.4
  • 46
    • 0029838377 scopus 로고    scopus 로고
    • Urinary excretion of apo(a) fragments. Role in apo(a) catabolism
    • Kostner KM, Maurer G, Huber K et al. Urinary excretion of apo(a) fragments. Role in apo(a) catabolism. Arterioscler Thromb Vasc Biol 1996; 16: 905-11.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 905-911
    • Kostner, K.M.1    Maurer, G.2    Huber, K.3
  • 47
    • 34047201878 scopus 로고    scopus 로고
    • In vivo turnover study demonstrates diminished clearance of lipoprotein(a) in hemodialysis patients
    • Frischmann ME, Kronenberg F, Trenkwalder E et al. In vivo turnover study demonstrates diminished clearance of lipoprotein(a) in hemodialysis patients. Kidney Int 2007; 71: 1036-43.
    • (2007) Kidney Int , vol.71 , pp. 1036-1043
    • Frischmann, M.E.1    Kronenberg, F.2    Trenkwalder, E.3
  • 49
    • 33845411733 scopus 로고    scopus 로고
    • Novel insights into Lp(a) physiology and pathogenicity: more questions than answers?
    • Koschinsky ML. Novel insights into Lp(a) physiology and pathogenicity: more questions than answers? Cardiovasc Hematol Disord Drug Targets 2006; 6: 267-78.
    • (2006) Cardiovasc Hematol Disord Drug Targets , vol.6 , pp. 267-278
    • Koschinsky, M.L.1
  • 50
    • 0025289037 scopus 로고
    • Lp(a): an interloper into the fibrinolytic system
    • Miles LA, Plow EF. Lp(a): an interloper into the fibrinolytic system. Thromb Haemost 1990; 63: 331-5.
    • (1990) Thromb Haemost , vol.63 , pp. 331-335
    • Miles, L.A.1    Plow, E.F.2
  • 51
    • 85027946492 scopus 로고    scopus 로고
    • Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis
    • Kamstrup PR, Tybjaerg-Hansen A, Nordestgaard BG. Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis. Arterioscler Thromb Vasc Biol 2012; 32: 1732-41.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1732-1741
    • Kamstrup, P.R.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 52
    • 84865125773 scopus 로고    scopus 로고
    • Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism
    • Helgadottir A, Gretarsdottir S, Thorleifsson G et al. Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. J Am Coll Cardiol 2012; 60: 722-9.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 722-729
    • Helgadottir, A.1    Gretarsdottir, S.2    Thorleifsson, G.3
  • 53
    • 0036090074 scopus 로고    scopus 로고
    • Direct interaction of the extracellular matrix protein DANCE with apolipoprotein(a) mediated by the kringle IV-type 2 domain
    • Kapetanopoulos A, Fresser F, Millonig G, Shaul Y, Baier G, Utermann G. Direct interaction of the extracellular matrix protein DANCE with apolipoprotein(a) mediated by the kringle IV-type 2 domain. Mol Genet Genomics 2002; 267: 440-6.
    • (2002) Mol Genet Genomics , vol.267 , pp. 440-446
    • Kapetanopoulos, A.1    Fresser, F.2    Millonig, G.3    Shaul, Y.4    Baier, G.5    Utermann, G.6
  • 54
    • 0242657000 scopus 로고    scopus 로고
    • Novel interaction of apolipoprotein(a) with β-2 glycoprotein I mediated by the kringle IV domain
    • Köchl S, Fresser F, Lobentanz E, Baier G, Utermann G. Novel interaction of apolipoprotein(a) with β-2 glycoprotein I mediated by the kringle IV domain. Blood 1997; 90: 1482-9.
    • (1997) Blood , vol.90 , pp. 1482-1489
    • Köchl, S.1    Fresser, F.2    Lobentanz, E.3    Baier, G.4    Utermann, G.5
  • 55
    • 0023652132 scopus 로고
    • Plasma lipoproteins: teaching old dogmas new tricks
    • Brown MS, Goldstein JL. Plasma lipoproteins: teaching old dogmas new tricks. Nature 1987; 330: 113-4.
    • (1987) Nature , vol.330 , pp. 113-114
    • Brown, M.S.1    Goldstein, J.L.2
  • 56
    • 0024448014 scopus 로고
    • Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation
    • Cushing GL, Gaubatz JW, Nava ML et al. Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation. Arteriosclerosis 1989; 9: 593-603.
    • (1989) Arteriosclerosis , vol.9 , pp. 593-603
    • Cushing, G.L.1    Gaubatz, J.W.2    Nava, M.L.3
  • 57
    • 0024456833 scopus 로고
    • Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients
    • Rath M, Niendorf A, Reblin T, Dietel M, Krebber H-J, Beisiegel U. Detection and quantification of lipoprotein(a) in the arterial wall of 107 coronary bypass patients. Arteriosclerosis 1989; 9: 579-92.
    • (1989) Arteriosclerosis , vol.9 , pp. 579-592
    • Rath, M.1    Niendorf, A.2    Reblin, T.3    Dietel, M.4    Krebber, H.-J.5    Beisiegel, U.6
  • 58
    • 0028898083 scopus 로고
    • Extraction of lipoprotein(a), apo B, and apo E from fresh human arterial wall and atherosclerotic plaques
    • Reblin T, Meyer N, Labeur C, Henne-Bruns D, Beisiegel U. Extraction of lipoprotein(a), apo B, and apo E from fresh human arterial wall and atherosclerotic plaques. Atherosclerosis 1995; 113: 179-88.
    • (1995) Atherosclerosis , vol.113 , pp. 179-188
    • Reblin, T.1    Meyer, N.2    Labeur, C.3    Henne-Bruns, D.4    Beisiegel, U.5
  • 60
    • 0028862017 scopus 로고
    • Apolipoprotein(a) deposition in atherosclerotic plaques of cerebral vessels - A potential role for endothelial cells in lesion formation
    • Jamieson DG, Usher DC, Rader DJ, Lavi E. Apolipoprotein(a) deposition in atherosclerotic plaques of cerebral vessels - A potential role for endothelial cells in lesion formation. Am J Pathol 1995; 147: 1567-74.
    • (1995) Am J Pathol , vol.147 , pp. 1567-1574
    • Jamieson, D.G.1    Usher, D.C.2    Rader, D.J.3    Lavi, E.4
  • 61
    • 79953031235 scopus 로고    scopus 로고
    • Differential expression of oxidized/native lipoprotein(a) and plasminogen in human carotid and cerebral artery plaques
    • Umahara T, Uchihara T, Yamada S et al. Differential expression of oxidized/native lipoprotein(a) and plasminogen in human carotid and cerebral artery plaques. Atherosclerosis 2011; 215: 392-8.
    • (2011) Atherosclerosis , vol.215 , pp. 392-398
    • Umahara, T.1    Uchihara, T.2    Yamada, S.3
  • 62
    • 0030882882 scopus 로고    scopus 로고
    • Lipoprotein(a) is a potent chemoattractant for human peripheral monocytes
    • Syrovets T, Thillet J, Chapman MJ, Simmet T. Lipoprotein(a) is a potent chemoattractant for human peripheral monocytes. Blood 1997; 90: 2027-36.
    • (1997) Blood , vol.90 , pp. 2027-2036
    • Syrovets, T.1    Thillet, J.2    Chapman, M.J.3    Simmet, T.4
  • 63
    • 0030868773 scopus 로고    scopus 로고
    • Apolipoprotein(a) induces monocyte chemotactic activity in human vascular endothelial cells
    • Poon M, Zhang X, Dunsky KG, Taubman MB, Harpel PC. Apolipoprotein(a) induces monocyte chemotactic activity in human vascular endothelial cells. Circulation 1997; 96: 2514-9.
    • (1997) Circulation , vol.96 , pp. 2514-2519
    • Poon, M.1    Zhang, X.2    Dunsky, K.G.3    Taubman, M.B.4    Harpel, P.C.5
  • 64
    • 0035861663 scopus 로고    scopus 로고
    • Stimulation of interleukin-8 production in human THP-1 macrophages by apolipoprotein (a): evidence for a critical involvement of elements in its C-terminal domain
    • Klezovitch O, Edelstein C, Scanu AM. Stimulation of interleukin-8 production in human THP-1 macrophages by apolipoprotein (a): evidence for a critical involvement of elements in its C-terminal domain. J Biol Chem 2001; 276: 46864-9.
    • (2001) J Biol Chem , vol.276 , pp. 46864-46869
    • Klezovitch, O.1    Edelstein, C.2    Scanu, A.M.3
  • 65
    • 0028293315 scopus 로고
    • Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice
    • Callow MJ, Stoltzfus LJ, Lawn RM, Rubin EM. Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. Proc Natl Acad Sci USA 1994; 91: 2130-4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2130-2134
    • Callow, M.J.1    Stoltzfus, L.J.2    Lawn, R.M.3    Rubin, E.M.4
  • 66
    • 0027145132 scopus 로고
    • Transgenic mice expressing high plasma concentrations of human Apolipoprotein B100 and lipoprotein(a)
    • Linton MF, Farese RV, Chiesa G et al. Transgenic mice expressing high plasma concentrations of human Apolipoprotein B100 and lipoprotein(a). J Clin Invest 1993; 92: 3029-37.
    • (1993) J Clin Invest , vol.92 , pp. 3029-3037
    • Linton, M.F.1    Farese, R.V.2    Chiesa, G.3
  • 67
    • 0033599343 scopus 로고    scopus 로고
    • Assembly of lipoprotein (a) in transgenic rabbits expressing human apolipoprotein (a)
    • Fan J, Araki M, Wu L et al. Assembly of lipoprotein (a) in transgenic rabbits expressing human apolipoprotein (a). Biochem Biophys Res Commun 1999; 255: 639-44.
    • (1999) Biochem Biophys Res Commun , vol.255 , pp. 639-644
    • Fan, J.1    Araki, M.2    Wu, L.3
  • 68
    • 0028951047 scopus 로고
    • Antifibrinolytic activity of apolipoprotein(a) in vivo: human apolipoprotein(a) transgenic mice are resistent to tissue plasminogen activator-mediated thrombolysis
    • Palabrica TM, Liu AC, Aronovitz MJ, Furie B, Lawn RM, Furie BC. Antifibrinolytic activity of apolipoprotein(a) in vivo: human apolipoprotein(a) transgenic mice are resistent to tissue plasminogen activator-mediated thrombolysis. Nat Med 1995; 1: 256-9.
    • (1995) Nat Med , vol.1 , pp. 256-259
    • Palabrica, T.M.1    Liu, A.C.2    Aronovitz, M.J.3    Furie, B.4    Lawn, R.M.5    Furie, B.C.6
  • 70
    • 0028832488 scopus 로고
    • Relative contributions of apolipoprotein(a) and apolipoprotein- B to the development of fatty lesions in the proximal aorta of mice
    • Mancini FP, Newland DL, Mooser V et al. Relative contributions of apolipoprotein(a) and apolipoprotein- B to the development of fatty lesions in the proximal aorta of mice. Arterioscler Thromb Vasc Biol 1995; 15: 1911-6.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1911-1916
    • Mancini, F.P.1    Newland, D.L.2    Mooser, V.3
  • 71
    • 0032516054 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a)
    • Sanan DA, Newland DL, Tao R et al. Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a). Proc Natl Acad Sci USA 1998; 95: 4544-9.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4544-4549
    • Sanan, D.A.1    Newland, D.L.2    Tao, R.3
  • 72
    • 59049086968 scopus 로고    scopus 로고
    • A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma
    • Bergmark C, Dewan A, Orsoni A et al. A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. J Lipid Res 2008; 49: 2230-9.
    • (2008) J Lipid Res , vol.49 , pp. 2230-2239
    • Bergmark, C.1    Dewan, A.2    Orsoni, A.3
  • 73
    • 9144233520 scopus 로고    scopus 로고
    • Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a)
    • Edelstein C, Pfaffinger D, Hinman J et al. Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a). J Biol Chem 2003; 278: 52841-7.
    • (2003) J Biol Chem , vol.278 , pp. 52841-52847
    • Edelstein, C.1    Pfaffinger, D.2    Hinman, J.3
  • 74
    • 21444447949 scopus 로고    scopus 로고
    • Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease
    • Tsimikas S, Brilakis ES, Miller ER et al. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med 2005; 353: 46-57.
    • (2005) N Engl J Med , vol.353 , pp. 46-57
    • Tsimikas, S.1    Brilakis, E.S.2    Miller, E.R.3
  • 75
    • 34547627109 scopus 로고    scopus 로고
    • Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity and 10-year cardiovascular outcomes: prospective results from the bruneck study
    • Kiechl S, Willeit J, Mayr M et al. Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity and 10-year cardiovascular outcomes: prospective results from the bruneck study. Arterioscler Thromb Vasc Biol 2007; 27: 1788-95.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1788-1795
    • Kiechl, S.1    Willeit, J.2    Mayr, M.3
  • 76
    • 77956495725 scopus 로고    scopus 로고
    • Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events
    • Tsimikas S, Mallat Z, Talmud PJ et al. Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events. J Am Coll Cardiol 2010; 56: 946-55.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 946-955
    • Tsimikas, S.1    Mallat, Z.2    Talmud, P.J.3
  • 77
    • 77952547617 scopus 로고    scopus 로고
    • Naturally occurring human plasminogen, like genetically related apolipoprotein(a), contains oxidized phosphatidylcholine adducts
    • Edelstein C, Pfaffinger D, Yang M, Hill JS, Scanu AM. Naturally occurring human plasminogen, like genetically related apolipoprotein(a), contains oxidized phosphatidylcholine adducts. Biochim Biophys Acta 2010; 1801: 738-45.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 738-745
    • Edelstein, C.1    Pfaffinger, D.2    Yang, M.3    Hill, J.S.4    Scanu, A.M.5
  • 78
    • 0024815586 scopus 로고
    • Lipoprotein(a) binds to fibronectin and has serine proteinase activity capable of cleaving it
    • Salonen EM, Jauhiainen M, Zardi L, Vaheri A, Ehnholm C. Lipoprotein(a) binds to fibronectin and has serine proteinase activity capable of cleaving it. EMBO J 1989; 8: 4035-40.
    • (1989) EMBO J , vol.8 , pp. 4035-4040
    • Salonen, E.M.1    Jauhiainen, M.2    Zardi, L.3    Vaheri, A.4    Ehnholm, C.5
  • 79
    • 0026101929 scopus 로고
    • Characterization of the enzyme activity of human plasma lipoprotein (a) using synthetic peptide substrates
    • Jauhiainen M, Metso J, Koskinen P, Ehnholm C. Characterization of the enzyme activity of human plasma lipoprotein (a) using synthetic peptide substrates. Biochem J 1991; 274: 491-6.
    • (1991) Biochem J , vol.274 , pp. 491-496
    • Jauhiainen, M.1    Metso, J.2    Koskinen, P.3    Ehnholm, C.4
  • 80
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH. Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest 1992; 90: 52-60.
    • (1992) J Clin Invest , vol.90 , pp. 52-60
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3    Lackner, C.4    Chiesa, G.5    Hobbs, H.H.6
  • 81
    • 0023393811 scopus 로고
    • Lp(a) glycoprotein phenotypes: inheritance and relation to Lp(a)-lipoprotein concentrations in plasma
    • Utermann G, Menzel HJ, Kraft HG, Duba HC, Kemmler HG, Seitz C. Lp(a) glycoprotein phenotypes: inheritance and relation to Lp(a)-lipoprotein concentrations in plasma. J Clin Invest 1987; 80: 458-65.
    • (1987) J Clin Invest , vol.80 , pp. 458-465
    • Utermann, G.1    Menzel, H.J.2    Kraft, H.G.3    Duba, H.C.4    Kemmler, H.G.5    Seitz, C.6
  • 82
    • 0023855450 scopus 로고
    • Genetics of the quantitative Lp(a) lipoprotein trait. I. Relation of Lp(a) glycoprotein phenotypes to Lp(a) lipoprotein concentrations in plasma
    • Utermann G, Kraft HG, Menzel HJ, Hopferwieser T, Seitz C. Genetics of the quantitative Lp(a) lipoprotein trait. I. Relation of Lp(a) glycoprotein phenotypes to Lp(a) lipoprotein concentrations in plasma. Hum Genet 1988; 78: 41-6.
    • (1988) Hum Genet , vol.78 , pp. 41-46
    • Utermann, G.1    Kraft, H.G.2    Menzel, H.J.3    Hopferwieser, T.4    Seitz, C.5
  • 83
    • 0023840851 scopus 로고
    • Genetics of quantitative Lp(a) lipoprotein trait. II. Inheritance of Lp(a) glycoprotein phenotypes
    • Utermann G, Duba C, Menzel HJ. Genetics of quantitative Lp(a) lipoprotein trait. II. Inheritance of Lp(a) glycoprotein phenotypes. Hum Genet 1988; 78: 47-50.
    • (1988) Hum Genet , vol.78 , pp. 47-50
    • Utermann, G.1    Duba, C.2    Menzel, H.J.3
  • 84
    • 0024543611 scopus 로고
    • Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation
    • Boerwinkle E, Menzel HJ, Kraft HG, Utermann G. Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation. Hum Genet 1989; 82: 73-8.
    • (1989) Hum Genet , vol.82 , pp. 73-78
    • Boerwinkle, E.1    Menzel, H.J.2    Kraft, H.G.3    Utermann, G.4
  • 85
    • 0032837868 scopus 로고    scopus 로고
    • Molecular basis of congenital Lp(a) deficiency: a frequent apo(a) 'null' mutation in Caucasians
    • Ogorelkova M, Gruber A, Utermann G. Molecular basis of congenital Lp(a) deficiency: a frequent apo(a) 'null' mutation in Caucasians. Hum Mol Genet 1999; 8: 2087-96.
    • (1999) Hum Mol Genet , vol.8 , pp. 2087-2096
    • Ogorelkova, M.1    Gruber, A.2    Utermann, G.3
  • 86
    • 0026666728 scopus 로고
    • Serum lipoprotein(a) levels in racially different populations
    • Cobbaert C, Kesteloot H. Serum lipoprotein(a) levels in racially different populations. Am J Epidemiol 1992; 136: 441-9.
    • (1992) Am J Epidemiol , vol.136 , pp. 441-449
    • Cobbaert, C.1    Kesteloot, H.2
  • 87
    • 0032892174 scopus 로고    scopus 로고
    • Genetic architecture and evolution of the lipoprotein(a) trait
    • Utermann G. Genetic architecture and evolution of the lipoprotein(a) trait. Curr Opin Lipidol 1999; 10: 133-41.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 133-141
    • Utermann, G.1
  • 88
    • 0025997058 scopus 로고
    • The NHLBI Twin Study: heritability of apolipoprotein A-I and B, and low density lipoprotein subclasses and concordance for lipoprotein(a)
    • Lamon-Fava S, Jimenez D, Christian JC et al. The NHLBI Twin Study: heritability of apolipoprotein A-I and B, and low density lipoprotein subclasses and concordance for lipoprotein(a). Atherosclerosis 1991; 91: 97-106.
    • (1991) Atherosclerosis , vol.91 , pp. 97-106
    • Lamon-Fava, S.1    Jimenez, D.2    Christian, J.C.3
  • 90
    • 0027179248 scopus 로고
    • Molecular definition of the extreme size polymorphism in apolipoprotein(a)
    • Lackner C, Cohen JC, Hobbs HH. Molecular definition of the extreme size polymorphism in apolipoprotein(a). Hum Mol Genet 1993; 2: 933-40.
    • (1993) Hum Mol Genet , vol.2 , pp. 933-940
    • Lackner, C.1    Cohen, J.C.2    Hobbs, H.H.3
  • 91
    • 0033058188 scopus 로고    scopus 로고
    • Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians
    • Scholz M, Kraft HG, Lingenhel A et al. Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians. Eur J Hum Genet 1999; 7: 169-78.
    • (1999) Eur J Hum Genet , vol.7 , pp. 169-178
    • Scholz, M.1    Kraft, H.G.2    Lingenhel, A.3
  • 92
    • 31344473090 scopus 로고    scopus 로고
    • Genetics of the Lp(a)/apo(a) system in an autochthonous Black African population from the Gabon
    • Schmidt K, Kraft HG, Parson W, Utermann G. Genetics of the Lp(a)/apo(a) system in an autochthonous Black African population from the Gabon. Eur J Hum Genet 2006; 14: 190-201.
    • (2006) Eur J Hum Genet , vol.14 , pp. 190-201
    • Schmidt, K.1    Kraft, H.G.2    Parson, W.3    Utermann, G.4
  • 93
    • 0030799057 scopus 로고    scopus 로고
    • The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans
    • Mooser V, Scheer D, Marcovina SM et al. The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans. Am J Hum Genet 1997; 61: 402-17.
    • (1997) Am J Hum Genet , vol.61 , pp. 402-417
    • Mooser, V.1    Scheer, D.2    Marcovina, S.M.3
  • 94
    • 0025905304 scopus 로고
    • Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups
    • Sandholzer C, Hallman DM, Saha N et al. Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups. Hum Genet 1991; 86: 607-14.
    • (1991) Hum Genet , vol.86 , pp. 607-614
    • Sandholzer, C.1    Hallman, D.M.2    Saha, N.3
  • 95
    • 0026509691 scopus 로고
    • Apolipoprotein(a) alleles determine lipoprotein(a) particle density and concentration in plasma
    • Kraft HG, Sandholzer C, Menzel HJ, Utermann G. Apolipoprotein(a) alleles determine lipoprotein(a) particle density and concentration in plasma. Arterioscler Thromb 1992; 12: 302-6.
    • (1992) Arterioscler Thromb , vol.12 , pp. 302-306
    • Kraft, H.G.1    Sandholzer, C.2    Menzel, H.J.3    Utermann, G.4
  • 96
    • 0029145665 scopus 로고
    • A pentanucleotide repeat polymorphism in the 5′ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians
    • Trommsdorff M, Köchl S, Lingenhel A et al. A pentanucleotide repeat polymorphism in the 5′ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians. J Clin Invest 1995; 96: 150-7.
    • (1995) J Clin Invest , vol.96 , pp. 150-157
    • Trommsdorff, M.1    Köchl, S.2    Lingenhel, A.3
  • 97
    • 0030808036 scopus 로고    scopus 로고
    • Polymorphisms in the apolipoprotein(a) gene and their relationship to allele size and plasma lipoprotein(a) concentration
    • Puckey LH, Lawn RM, Knight BL. Polymorphisms in the apolipoprotein(a) gene and their relationship to allele size and plasma lipoprotein(a) concentration. Hum Mol Genet 1997; 6: 1099-107.
    • (1997) Hum Mol Genet , vol.6 , pp. 1099-1107
    • Puckey, L.H.1    Lawn, R.M.2    Knight, B.L.3
  • 98
    • 0035311403 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians
    • Ogorelkova M, Kraft HG, Ehnholm C, Utermann G. Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians. Hum Mol Genet 2001; 10: 815-24.
    • (2001) Hum Mol Genet , vol.10 , pp. 815-824
    • Ogorelkova, M.1    Kraft, H.G.2    Ehnholm, C.3    Utermann, G.4
  • 99
    • 77952487856 scopus 로고    scopus 로고
    • Comprehensive analysis of genomic variation in the LPA locus and its relationship to plasma lipoprotein(a) in South Asians, Chinese, and European Caucasians
    • Lanktree MB, Anand SS, Yusuf S, Hegele RA. Comprehensive analysis of genomic variation in the LPA locus and its relationship to plasma lipoprotein(a) in South Asians, Chinese, and European Caucasians. Circ Cardiovasc Genet 2010; 3: 39-46.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 39-46
    • Lanktree, M.B.1    Anand, S.S.2    Yusuf, S.3    Hegele, R.A.4
  • 100
    • 79551558751 scopus 로고    scopus 로고
    • Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey
    • Dumitrescu L, Glenn K, Brown-Gentry K et al. Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey. PLoS One 2011; 6: e16604.
    • (2011) PLoS One , vol.6
    • Dumitrescu, L.1    Glenn, K.2    Brown-Gentry, K.3
  • 101
    • 33846168084 scopus 로고    scopus 로고
    • Three single-nucleotide polymorphisms in LPA account for the majority of lipoprotein(A) level elevation in African Americans compared to European Americans
    • Chretie JP, Coresh J, Berthier-Schaad Y et al. Three single-nucleotide polymorphisms in LPA account for the majority of lipoprotein(A) level elevation in African Americans compared to European Americans. J Med Genet 2006; 43: 917-23.
    • (2006) J Med Genet , vol.43 , pp. 917-923
    • Chretie, J.P.1    Coresh, J.2    Berthier-Schaad, Y.3
  • 102
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • Teslovich TM, Musunuru K, Smith AV et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010; 466: 707-13.
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3
  • 103
    • 58149161560 scopus 로고    scopus 로고
    • Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
    • Aulchenko YS, Ripatti S, Lindquist I et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2009; 41: 47-55.
    • (2009) Nat Genet , vol.41 , pp. 47-55
    • Aulchenko, Y.S.1    Ripatti, S.2    Lindquist, I.3
  • 104
    • 57149114180 scopus 로고    scopus 로고
    • Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA Study sheds new light on intergenic regions
    • Heid IM, Boes E, Müller A et al. Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA Study sheds new light on intergenic regions. Circ Cardiovasc Genet 2008; 1: 10-20.
    • (2008) Circ Cardiovasc Genet , vol.1 , pp. 10-20
    • Heid, I.M.1    Boes, E.2    Müller, A.3
  • 105
    • 18544372620 scopus 로고    scopus 로고
    • A comprehensive linkage analysis for myocardial infarction and its related risk factors
    • Broeckel U, Hengstenberg C, Mayer B et al. A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet 2002; 30: 210-4.
    • (2002) Nat Genet , vol.30 , pp. 210-214
    • Broeckel, U.1    Hengstenberg, C.2    Mayer, B.3
  • 106
    • 33846315479 scopus 로고    scopus 로고
    • Multiple QTL influence the serum Lp(a) concentration: a genome-wide linkage screen in the PROCARDIS study
    • Barlera S, Specchia C, Farrall M et al. Multiple QTL influence the serum Lp(a) concentration: a genome-wide linkage screen in the PROCARDIS study. Eur J Hum Genet 2007; 15: 221-7.
    • (2007) Eur J Hum Genet , vol.15 , pp. 221-227
    • Barlera, S.1    Specchia, C.2    Farrall, M.3
  • 107
    • 54549096882 scopus 로고    scopus 로고
    • Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels
    • Lopez S, Buil A, Ordonez J et al. Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels. Eur J Hum Genet 2008; 16: 1372-9.
    • (2008) Eur J Hum Genet , vol.16 , pp. 1372-1379
    • Lopez, S.1    Buil, A.2    Ordonez, J.3
  • 108
    • 44949201115 scopus 로고    scopus 로고
    • A genome-wide association study identifies protein quantitative trait loci (pQTLs)
    • Melzer D, Perry JR, Hernandez D et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet 2008; 4: e1000072.
    • (2008) PLoS Genet , vol.4
    • Melzer, D.1    Perry, J.R.2    Hernandez, D.3
  • 109
    • 67649729589 scopus 로고    scopus 로고
    • Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q
    • Ober C, Nord AS, Thompson EE et al. Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. J Lipid Res 2009; 50: 798-806.
    • (2009) J Lipid Res , vol.50 , pp. 798-806
    • Ober, C.1    Nord, A.S.2    Thompson, E.E.3
  • 110
    • 79960699966 scopus 로고    scopus 로고
    • Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts
    • Zabaneh D, Kumari M, Sandhu M et al. Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14, 500 participants of six White European cohorts. Atherosclerosis 2011; 217: 447-51.
    • (2011) Atherosclerosis , vol.217 , pp. 447-451
    • Zabaneh, D.1    Kumari, M.2    Sandhu, M.3
  • 111
    • 79953691816 scopus 로고    scopus 로고
    • Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study
    • Kivimaki M, Magnussen CG, Juonala M et al. Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study. Int J Epidemiol 2011; 40: 470-8.
    • (2011) Int J Epidemiol , vol.40 , pp. 470-478
    • Kivimaki, M.1    Magnussen, C.G.2    Juonala, M.3
  • 112
    • 84863037215 scopus 로고    scopus 로고
    • Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes
    • Qi Q, Workalemahu T, Zhang C, Hu FB, Qi L. Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes. Eur Heart J 2012; 33: 325-34.
    • (2012) Eur Heart J , vol.33 , pp. 325-334
    • Qi, Q.1    Workalemahu, T.2    Zhang, C.3    Hu, F.B.4    Qi, L.5
  • 113
    • 0029916008 scopus 로고    scopus 로고
    • Frequency distributions of apolipoprotein(a) kringle IV repeat alleles and their effects on lipoprotein(a) levels in Caucasian, Asian, and African populations: the distribution of null alleles is non-random
    • Kraft HG, Lingenhel A, Pang RWC et al. Frequency distributions of apolipoprotein(a) kringle IV repeat alleles and their effects on lipoprotein(a) levels in Caucasian, Asian, and African populations: the distribution of null alleles is non-random. Eur J Hum Genet 1996; 4: 74-87.
    • (1996) Eur J Hum Genet , vol.4 , pp. 74-87
    • Kraft, H.G.1    Lingenhel, A.2    Pang, R.W.C.3
  • 114
  • 115
    • 53249090242 scopus 로고    scopus 로고
    • LPA and PLG sequence variation and kringle IV-2 copy number in two populations
    • Crawford DC, Peng Z, Cheng JF et al. LPA and PLG sequence variation and kringle IV-2 copy number in two populations. Hum Hered 2008; 66: 199-209.
    • (2008) Hum Hered , vol.66 , pp. 199-209
    • Crawford, D.C.1    Peng, Z.2    Cheng, J.F.3
  • 116
    • 79551551096 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans
    • Deo RC, Wilson JG, Xing C et al. Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans. PLoS One 2011; 6: e14581.
    • (2011) PLoS One , vol.6
    • Deo, R.C.1    Wilson, J.G.2    Xing, C.3
  • 117
    • 42049104360 scopus 로고    scopus 로고
    • High levels of inflammatory biomarkers are associated with increased allele-specific apolipoprotein(a) levels in African-Americans
    • Anuurad E, Rubin J, Chiem A, Tracy RP, Pearson TA, Berglund L. High levels of inflammatory biomarkers are associated with increased allele-specific apolipoprotein(a) levels in African-Americans. J Clin Endocrinol Metab 2008; 93: 1482-8.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1482-1488
    • Anuurad, E.1    Rubin, J.2    Chiem, A.3    Tracy, R.P.4    Pearson, T.A.5    Berglund, L.6
  • 118
    • 0025969527 scopus 로고
    • Variation in Lp(a) levels and apo(a) isoform frequencies in five baboon subspecies
    • Williams-Blangero S, Rainwater DL. Variation in Lp(a) levels and apo(a) isoform frequencies in five baboon subspecies. Hum Biol 1991; 63: 65-76.
    • (1991) Hum Biol , vol.63 , pp. 65-76
    • Williams-Blangero, S.1    Rainwater, D.L.2
  • 119
    • 34047192665 scopus 로고    scopus 로고
    • Lipoprotein metabolism and lipid management in chronic kidney disease
    • Kwan BCH, Kronenberg F, Beddhu S, Cheung AK. Lipoprotein metabolism and lipid management in chronic kidney disease. J Am Soc Nephrol 2007; 18: 1246-61.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1246-1261
    • Kwan, B.C.H.1    Kronenberg, F.2    Beddhu, S.3    Cheung, A.K.4
  • 120
    • 0033980288 scopus 로고    scopus 로고
    • Lipoprotein(a) serum concentrations and apolipoprotein(a) phenotypes in mild and moderate renal failure
    • Kronenberg F, Kuen E, Ritz E et al. Lipoprotein(a) serum concentrations and apolipoprotein(a) phenotypes in mild and moderate renal failure. J Am Soc Nephrol 2000; 11: 105-15.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 105-115
    • Kronenberg, F.1    Kuen, E.2    Ritz, E.3
  • 121
    • 0027475415 scopus 로고
    • Elevated plasma concentrations of lipoprotein(a) in patients with end-stage renal disease are not related to the size polymorphism of apolipoprotein(a)
    • Dieplinger H, Lackner C, Kronenberg F et al. Elevated plasma concentrations of lipoprotein(a) in patients with end-stage renal disease are not related to the size polymorphism of apolipoprotein(a). J Clin Invest 1993; 91: 397-401.
    • (1993) J Clin Invest , vol.91 , pp. 397-401
    • Dieplinger, H.1    Lackner, C.2    Kronenberg, F.3
  • 122
    • 0029101292 scopus 로고
    • Multicenter study of lipoprotein(a) and apolipoprotein(a) phenotypes in patients with end-stage renal disease treated by hemodialysis or continuous ambulatory peritoneal dialysis
    • Kronenberg F, König P, Neyer U et al. Multicenter study of lipoprotein(a) and apolipoprotein(a) phenotypes in patients with end-stage renal disease treated by hemodialysis or continuous ambulatory peritoneal dialysis. J Am Soc Nephrol 1995; 6: 110-20.
    • (1995) J Am Soc Nephrol , vol.6 , pp. 110-120
    • Kronenberg, F.1    König, P.2    Neyer, U.3
  • 123
    • 0031819896 scopus 로고    scopus 로고
    • Apo(a)-isoform size, nutritional status and inflammatory markers in chronic renal failure
    • Stenvinkel P, Heimbürger O, Tuck CH, Berglund L. Apo(a)-isoform size, nutritional status and inflammatory markers in chronic renal failure. Kidney Int 1998; 53: 1336-42.
    • (1998) Kidney Int , vol.53 , pp. 1336-1342
    • Stenvinkel, P.1    Heimbürger, O.2    Tuck, C.H.3    Berglund, L.4
  • 124
    • 0032935896 scopus 로고    scopus 로고
    • Inflammation enhances cardiovascular risk and mortality in hemodialysis patients
    • Zimmermann J, Herrlinger S, Pruy A, Metzger T, Wanner C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int 1999; 55: 648-58.
    • (1999) Kidney Int , vol.55 , pp. 648-658
    • Zimmermann, J.1    Herrlinger, S.2    Pruy, A.3    Metzger, T.4    Wanner, C.5
  • 125
    • 0027492029 scopus 로고
    • Elevated plasma lipoprotein(a) in patients with the nephrotic syndrome
    • Wanner C, Rader D, Bartens W et al. Elevated plasma lipoprotein(a) in patients with the nephrotic syndrome. Ann Intern Med 1993; 119: 263-9.
    • (1993) Ann Intern Med , vol.119 , pp. 263-269
    • Wanner, C.1    Rader, D.2    Bartens, W.3
  • 126
    • 1642480008 scopus 로고    scopus 로고
    • The apolipoprotein(a) size polymorphism is associated with nephrotic syndrome
    • Kronenberg F, Lingenhel A, Lhotta K et al. The apolipoprotein(a) size polymorphism is associated with nephrotic syndrome. Kidney Int 2004; 65: 606-12.
    • (2004) Kidney Int , vol.65 , pp. 606-612
    • Kronenberg, F.1    Lingenhel, A.2    Lhotta, K.3
  • 127
    • 0031927583 scopus 로고    scopus 로고
    • Evidence for increased synthesis of lipoprotein(a) in the nephrotic syndrome
    • De Sain-vanderVelden MGM, Reijngoud DJ, Kaysen GA et al. Evidence for increased synthesis of lipoprotein(a) in the nephrotic syndrome. J Am Soc Nephrol 1998; 9: 1474-81.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1474-1481
    • De Sain-vanderVelden, M.G.M.1    Reijngoud, D.J.2    Kaysen, G.A.3
  • 128
    • 0028168224 scopus 로고
    • Apolipoprotein(a) phenotype-associated decrease in lipoprotein(a) plasma concentrations after renal transplantation
    • Kronenberg F, König P, Lhotta K et al. Apolipoprotein(a) phenotype-associated decrease in lipoprotein(a) plasma concentrations after renal transplantation. Arterioscler Thromb 1994; 14: 1399-404.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1399-1404
    • Kronenberg, F.1    König, P.2    Lhotta, K.3
  • 130
    • 0345004985 scopus 로고    scopus 로고
    • Lipoprotein(a) plasma concentrations after renal transplantation: a prospective evaluation after 4 years of follow-up
    • Kerschdorfer L, König P, Neyer U et al. Lipoprotein(a) plasma concentrations after renal transplantation: a prospective evaluation after 4 years of follow-up. Atherosclerosis 1999; 144: 381-91.
    • (1999) Atherosclerosis , vol.144 , pp. 381-391
    • Kerschdorfer, L.1    König, P.2    Neyer, U.3
  • 131
    • 0032932091 scopus 로고    scopus 로고
    • The low molecular weight apo(a) phenotype is an independent predictor for coronary artery disease in hemodialysis patients: a prospective follow-up
    • Kronenberg F, Neyer U, Lhotta K et al. The low molecular weight apo(a) phenotype is an independent predictor for coronary artery disease in hemodialysis patients: a prospective follow-up. J Am Soc Nephrol 1999; 10: 1027-36.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1027-1036
    • Kronenberg, F.1    Neyer, U.2    Lhotta, K.3
  • 132
    • 26944462059 scopus 로고    scopus 로고
    • High lipoprotein(a) levels and small apolipoprotein(a) size prospectively predict cardiovascular events in dialysis patients
    • Longenecker JC, Klag MJ, Marcovina SM et al. High lipoprotein(a) levels and small apolipoprotein(a) size prospectively predict cardiovascular events in dialysis patients. J Am Soc Nephrol 2005; 16: 1794-802.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1794-1802
    • Longenecker, J.C.1    Klag, M.J.2    Marcovina, S.M.3
  • 133
    • 0030027648 scopus 로고    scopus 로고
    • Apolipoprotein(a) kringle 4-containing fragments in urine. Relationship to plasma levels of lipoprotein(a)
    • Mooser V, Seabra MC, Abedin M, Landschulz KT, Marcovina S, Hobbs HH. Apolipoprotein(a) kringle 4-containing fragments in urine. Relationship to plasma levels of lipoprotein(a). J Clin Invest 1996; 97: 858-64.
    • (1996) J Clin Invest , vol.97 , pp. 858-864
    • Mooser, V.1    Seabra, M.C.2    Abedin, M.3    Landschulz, K.T.4    Marcovina, S.5    Hobbs, H.H.6
  • 134
    • 0031867582 scopus 로고    scopus 로고
    • Decreased urinary apolipoprotein (a) excretion in patients with impaired renal function
    • Kostner KM, Clodi M, Bodlaj G et al. Decreased urinary apolipoprotein (a) excretion in patients with impaired renal function. Eur J Clin Invest 1998; 28: 447-52.
    • (1998) Eur J Clin Invest , vol.28 , pp. 447-452
    • Kostner, K.M.1    Clodi, M.2    Bodlaj, G.3
  • 137
    • 0031814605 scopus 로고    scopus 로고
    • Insulin and 2-hour glucose levels are inversely related to Lp(a) concentrations controlled for LPA genotype
    • Rainwater DL, Haffner SM. Insulin and 2-hour glucose levels are inversely related to Lp(a) concentrations controlled for LPA genotype. Arterioscler Thromb Vasc Biol 1998; 18: 1335-41.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1335-1341
    • Rainwater, D.L.1    Haffner, S.M.2
  • 138
    • 0032933140 scopus 로고    scopus 로고
    • Insulin suppresses apolipoprotein(a) synthesis by primary cultures of cynomolgus monkey hepatocytes
    • Neele DM, de Wit EC, Princen HM. Insulin suppresses apolipoprotein(a) synthesis by primary cultures of cynomolgus monkey hepatocytes. Diabetologia 1999; 42: 41-4.
    • (1999) Diabetologia , vol.42 , pp. 41-44
    • Neele, D.M.1    de Wit, E.C.2    Princen, H.M.3
  • 139
    • 0026355887 scopus 로고
    • Relationship of lipoprotein(a) to variables of coagulation and fibrinolysis in a healthy population
    • Heinrich J, Sandkamp M, Kokott R, Schulte H, Assmann G. Relationship of lipoprotein(a) to variables of coagulation and fibrinolysis in a healthy population. Clin Chem 1991; 37: 1950-4.
    • (1991) Clin Chem , vol.37 , pp. 1950-1954
    • Heinrich, J.1    Sandkamp, M.2    Kokott, R.3    Schulte, H.4    Assmann, G.5
  • 140
    • 33746862148 scopus 로고    scopus 로고
    • Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women
    • Salpeter SR, Walsh JM, Ormiston TM, Greyber E, Buckley NS, Salpeter EE. Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes Obes Metab 2006; 8: 538-54.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 538-554
    • Salpeter, S.R.1    Walsh, J.M.2    Ormiston, T.M.3    Greyber, E.4    Buckley, N.S.5    Salpeter, E.E.6
  • 141
    • 51549098795 scopus 로고    scopus 로고
    • Effects of non-oral postmenopausal hormone therapy on markers of cardiovascular risk: a systematic review
    • Hemelaar M, Van der Mooren MJ, Rad M, Kluft C, Kenemans P. Effects of non-oral postmenopausal hormone therapy on markers of cardiovascular risk: a systematic review. Fertil Steril 2008; 90: 642-72.
    • (2008) Fertil Steril , vol.90 , pp. 642-672
    • Hemelaar, M.1    Van der Mooren, M.J.2    Rad, M.3    Kluft, C.4    Kenemans, P.5
  • 142
    • 0035035574 scopus 로고    scopus 로고
    • Effects of postmenopausal hormone replacement therapy on lipid, lipoprotein, and apolipoprotein (a) concentrations: analysis of studies published from 1974-2000
    • Godsland IF. Effects of postmenopausal hormone replacement therapy on lipid, lipoprotein, and apolipoprotein (a) concentrations: analysis of studies published from 1974-2000. Fertil Steril 2001; 75: 898-915.
    • (2001) Fertil Steril , vol.75 , pp. 898-915
    • Godsland, I.F.1
  • 144
    • 1042291149 scopus 로고    scopus 로고
    • Growth hormone induces low-density lipoprotein clearance but not bile acid synthesis in humans
    • Lind S, Rudling M, Ericsson S et al. Growth hormone induces low-density lipoprotein clearance but not bile acid synthesis in humans. Arterioscler Thromb Vasc Biol 2004; 24: 349-56.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 349-356
    • Lind, S.1    Rudling, M.2    Ericsson, S.3
  • 145
    • 18844375867 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on insulin-like growth factor (IGF)-I, IGF-II and IGF binding protein (IGFBP)-1 to IGFBP-4: implications for cardiovascular risk
    • Heald A, Kaushal K, Anderson S et al. Effects of hormone replacement therapy on insulin-like growth factor (IGF)-I, IGF-II and IGF binding protein (IGFBP)-1 to IGFBP-4: implications for cardiovascular risk. Gynecol Endocrinol 2005; 20: 176-82.
    • (2005) Gynecol Endocrinol , vol.20 , pp. 176-182
    • Heald, A.1    Kaushal, K.2    Anderson, S.3
  • 146
  • 147
    • 0029906321 scopus 로고    scopus 로고
    • Hormonal regulation of serum lipoprotein (a) levels: effects of parenteral administration of estrogen or testosterone in males
    • Berglund L, Carlström K, Stege R et al. Hormonal regulation of serum lipoprotein (a) levels: effects of parenteral administration of estrogen or testosterone in males. J Clin Endocrinol Metab 1996; 81: 2633-7.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2633-2637
    • Berglund, L.1    Carlström, K.2    Stege, R.3
  • 148
    • 0028177457 scopus 로고
    • Lack of association between sex hormones and Lp(a) concentrations in American and Finnish men
    • Haffner SM, Mykkanen L, Gruber KK, Rainwater DL, Laakso M. Lack of association between sex hormones and Lp(a) concentrations in American and Finnish men. Arterioscler Thromb 1994; 14: 19-24.
    • (1994) Arterioscler Thromb , vol.14 , pp. 19-24
    • Haffner, S.M.1    Mykkanen, L.2    Gruber, K.K.3    Rainwater, D.L.4    Laakso, M.5
  • 149
    • 84856800207 scopus 로고    scopus 로고
    • Update in lipid alterations in subclinical hypothyroidism
    • Pearce EN. Update in lipid alterations in subclinical hypothyroidism. J Clin Endocrinol Metab 2012; 97: 326-33.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 326-333
    • Pearce, E.N.1
  • 150
    • 0033771131 scopus 로고    scopus 로고
    • Changes in lipoprotein(a) levels in overt and subclinical hypothyroidism before and during treatment
    • Tzotzas T, Krassas GE, Konstantinidis T, Bougoulia M. Changes in lipoprotein(a) levels in overt and subclinical hypothyroidism before and during treatment. Thyroid 2000; 10: 803-8.
    • (2000) Thyroid , vol.10 , pp. 803-808
    • Tzotzas, T.1    Krassas, G.E.2    Konstantinidis, T.3    Bougoulia, M.4
  • 151
    • 17944382933 scopus 로고    scopus 로고
    • TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism: a double blind, placebo-controlled trial (Basel Thyroid Study)
    • Meier C, Staub JJ, Roth CB et al. TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism: a double blind, placebo-controlled trial (Basel Thyroid Study). J Clin Endocrinol Metab 2001; 86: 4860-6.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4860-4866
    • Meier, C.1    Staub, J.J.2    Roth, C.B.3
  • 152
    • 0027733821 scopus 로고
    • Effect of thyroid function on concentrations of lipoprotein(a)
    • Engler H, Riesen WF. Effect of thyroid function on concentrations of lipoprotein(a). Clin Chem 1993; 39: 2466-9.
    • (1993) Clin Chem , vol.39 , pp. 2466-2469
    • Engler, H.1    Riesen, W.F.2
  • 155
    • 78650309921 scopus 로고    scopus 로고
    • Lipid lowering with thyroid hormone and thyromimetics
    • Angelin B, Rudling M. Lipid lowering with thyroid hormone and thyromimetics. Curr Opin Lipidol 2010; 21: 499-506.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 499-506
    • Angelin, B.1    Rudling, M.2
  • 156
    • 77949349469 scopus 로고    scopus 로고
    • Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia
    • Ladenson PW, Kristensen JD, Ridgway EC et al. Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia. N Engl J Med 2010; 362: 906-16.
    • (2010) N Engl J Med , vol.362 , pp. 906-916
    • Ladenson, P.W.1    Kristensen, J.D.2    Ridgway, E.C.3
  • 157
    • 67649713432 scopus 로고    scopus 로고
    • The thyromimetic T-0681 protects from atherosclerosis
    • Tancevski I, Wehinger A, Demetz E et al. The thyromimetic T-0681 protects from atherosclerosis. J Lipid Res 2009; 50: 938-44.
    • (2009) J Lipid Res , vol.50 , pp. 938-944
    • Tancevski, I.1    Wehinger, A.2    Demetz, E.3
  • 158
    • 77649284831 scopus 로고    scopus 로고
    • The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice
    • Tancevski I, Demetz E, Eller P et al. The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice. PLoS One 2010; 5: e8722.
    • (2010) PLoS One , vol.5
    • Tancevski, I.1    Demetz, E.2    Eller, P.3
  • 159
    • 0027439812 scopus 로고
    • Growth hormone treatment of growth hormone-deficient adults results in a marked increase in Lp(a) and HDL cholesterol concentrations
    • Edén S, Wiklund O, Oscarsson J, Rosén T, Bengtsson B-Å. Growth hormone treatment of growth hormone-deficient adults results in a marked increase in Lp(a) and HDL cholesterol concentrations. Arterioscler Thromb 1993; 13: 296-301.
    • (1993) Arterioscler Thromb , vol.13 , pp. 296-301
    • Edén, S.1    Wiklund, O.2    Oscarsson, J.3    Rosén, T.4    Bengtsson, B.-A.5
  • 160
    • 0029073215 scopus 로고
    • Effect of short-term treatment with recombinant human growth hormone on lipids and lipoproteins in women and men without growth hormone disturbances
    • Hansen PS, Kassem M, Brixen K, Klausen IC, Mosekilde L, Faergeman O. Effect of short-term treatment with recombinant human growth hormone on lipids and lipoproteins in women and men without growth hormone disturbances. Metabolism 1995; 44: 725-9.
    • (1995) Metabolism , vol.44 , pp. 725-729
    • Hansen, P.S.1    Kassem, M.2    Brixen, K.3    Klausen, I.C.4    Mosekilde, L.5    Faergeman, O.6
  • 161
    • 0029591531 scopus 로고
    • Effects of 1 year of growth hormone therapy on serum lipoprotein levels in growth hormone-deficient adults - Influence of gender and apo(a) and ApoE phenotypes
    • Johannsson G, Oscarsson J, Rosén T et al. Effects of 1 year of growth hormone therapy on serum lipoprotein levels in growth hormone-deficient adults - Influence of gender and apo(a) and ApoE phenotypes. Arterioscler Thromb Vasc Biol 1995; 15: 2142-50.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 2142-2150
    • Johannsson, G.1    Oscarsson, J.2    Rosén, T.3
  • 162
    • 0030828619 scopus 로고    scopus 로고
    • Anomalies of lipoprotein pattern and fibrinolysis in acromegalic patients: relation to growth hormone levels and insulin-like growth factor I
    • Wildbrett J, Hanefeld M, Fucker K et al. Anomalies of lipoprotein pattern and fibrinolysis in acromegalic patients: relation to growth hormone levels and insulin-like growth factor I. Exp Clin Endocrinol Diabetes 1997; 105: 331-5.
    • (1997) Exp Clin Endocrinol Diabetes , vol.105 , pp. 331-335
    • Wildbrett, J.1    Hanefeld, M.2    Fucker, K.3
  • 163
    • 0031435455 scopus 로고    scopus 로고
    • Increased plasma concentrations of LDL-unbound apo(a) in patients with end-stage renal disease
    • Trenkwalder E, Gruber A, König P, Dieplinger H, Kronenberg F. Increased plasma concentrations of LDL-unbound apo(a) in patients with end-stage renal disease. Kidney Int 1997; 52: 1685-92.
    • (1997) Kidney Int , vol.52 , pp. 1685-1692
    • Trenkwalder, E.1    Gruber, A.2    König, P.3    Dieplinger, H.4    Kronenberg, F.5
  • 164
    • 0028985381 scopus 로고
    • Effect of the number of apolipoprotein(a) kringle 4 domains on immunochemical measurements of lipoprotein(a)
    • Marcovina SM, Albers JJ, Gabel B, Koschinsky ML, Gaur VP. Effect of the number of apolipoprotein(a) kringle 4 domains on immunochemical measurements of lipoprotein(a). Clin Chem 1995; 41: 246-55.
    • (1995) Clin Chem , vol.41 , pp. 246-255
    • Marcovina, S.M.1    Albers, J.J.2    Gabel, B.3    Koschinsky, M.L.4    Gaur, V.P.5
  • 165
    • 0033634997 scopus 로고    scopus 로고
    • Use of a reference material proposed by the international federation of clinical chemistry and laboratory medicine to evaluate analytical methods for the determination of plasma lipoprotein(a)
    • Marcovina SM, Albers JJ, Scanu AM et al. Use of a reference material proposed by the international federation of clinical chemistry and laboratory medicine to evaluate analytical methods for the determination of plasma lipoprotein(a). Clin Chem 2000; 46: 1956-67.
    • (2000) Clin Chem , vol.46 , pp. 1956-1967
    • Marcovina, S.M.1    Albers, J.J.2    Scanu, A.M.3
  • 166
    • 3042850437 scopus 로고    scopus 로고
    • Lipoprotein(a)- and low-density lipoprotein-derived cholesterol in nephrotic syndrome: Impact on lipid-lowering therapy?
    • Kronenberg F, Lingenhel A, Lhotta K et al. Lipoprotein(a)- and low-density lipoprotein-derived cholesterol in nephrotic syndrome: Impact on lipid-lowering therapy? Kidney Int 2004; 66: 348-54.
    • (2004) Kidney Int , vol.66 , pp. 348-354
    • Kronenberg, F.1    Lingenhel, A.2    Lhotta, K.3
  • 167
    • 0035999523 scopus 로고    scopus 로고
    • Issues concerning the monitoring of statin therapy in hypercholesterolemic subjects with high plasma lipoprotein(a) levels
    • Scanu AM, Hinman J. Issues concerning the monitoring of statin therapy in hypercholesterolemic subjects with high plasma lipoprotein(a) levels. Lipids 2002; 37: 439-44.
    • (2002) Lipids , vol.37 , pp. 439-444
    • Scanu, A.M.1    Hinman, J.2
  • 168
    • 33748251332 scopus 로고    scopus 로고
    • Plasma lipoprotein(a) levels and LDL-cholesterol lowering response to statin therapy in patients with heterozygous familial hypercholesterolemia
    • Miltiadous G, Saougos V, Cariolou M, Elisaf MS. Plasma lipoprotein(a) levels and LDL-cholesterol lowering response to statin therapy in patients with heterozygous familial hypercholesterolemia. Ann Clin Lab Sci 2006; 36: 353-5.
    • (2006) Ann Clin Lab Sci , vol.36 , pp. 353-355
    • Miltiadous, G.1    Saougos, V.2    Cariolou, M.3    Elisaf, M.S.4
  • 169
    • 84860271201 scopus 로고    scopus 로고
    • Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)
    • Deshmukh HA, Colhoun HM, Johnson T et al. Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). J Lipid Res 2012; 53: 1000-11.
    • (2012) J Lipid Res , vol.53 , pp. 1000-1011
    • Deshmukh, H.A.1    Colhoun, H.M.2    Johnson, T.3
  • 170
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert H, Konig IR, Kathiresan S et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011; 43: 333-8.
    • (2011) Nat Genet , vol.43 , pp. 333-338
    • Schunkert, H.1    Konig, I.R.2    Kathiresan, S.3
  • 171
    • 0022656494 scopus 로고
    • Apolipoprotein E isoforms, serum cholesterol, and cancer
    • Katan MB. Apolipoprotein E isoforms, serum cholesterol, and cancer. Lancet 1986; 1: 507-8.
    • (1986) Lancet , vol.1 , pp. 507-508
    • Katan, M.B.1
  • 172
    • 0025365313 scopus 로고
    • Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia
    • Seed M, Hoppichler F, Reaveley D et al. Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med 1990; 322: 1494-9.
    • (1990) N Engl J Med , vol.322 , pp. 1494-1499
    • Seed, M.1    Hoppichler, F.2    Reaveley, D.3
  • 173
    • 0026560389 scopus 로고
    • Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease
    • Sandholzer C, Boerwinkle E, Saha N, Tong MC, Utermann G. Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease. J Clin Invest 1992; 89: 1040-6.
    • (1992) J Clin Invest , vol.89 , pp. 1040-1046
    • Sandholzer, C.1    Boerwinkle, E.2    Saha, N.3    Tong, M.C.4    Utermann, G.5
  • 174
    • 0026700306 scopus 로고
    • Apo(a) isoforms predict risk for coronary heart disease: a study in six populations
    • Sandholzer C, Saha N, Kark JD et al. Apo(a) isoforms predict risk for coronary heart disease: a study in six populations. Arterioscler Thromb 1992; 12: 1214-26.
    • (1992) Arterioscler Thromb , vol.12 , pp. 1214-1226
    • Sandholzer, C.1    Saha, N.2    Kark, J.D.3
  • 175
    • 0030014389 scopus 로고    scopus 로고
    • Apolipoprotein(a) Kringle IV repeat number predicts risk for coronary heart disease
    • Kraft HG, Lingenhel A, Köchl S et al. Apolipoprotein(a) Kringle IV repeat number predicts risk for coronary heart disease. Arterioscler Thromb Vasc Biol 1996; 16: 713-9.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 713-719
    • Kraft, H.G.1    Lingenhel, A.2    Köchl, S.3
  • 176
    • 82955173728 scopus 로고    scopus 로고
    • Genetic variants in the apolipoprotein(a) gene and coronary heart disease
    • Li Y, Luke MM, Shiffman D, Devlin JJ. Genetic variants in the apolipoprotein(a) gene and coronary heart disease. Circ Cardiovasc Genet 2011; 4: 565-73.
    • (2011) Circ Cardiovasc Genet , vol.4 , pp. 565-573
    • Li, Y.1    Luke, M.M.2    Shiffman, D.3    Devlin, J.J.4
  • 177
    • 68949200960 scopus 로고    scopus 로고
    • Conditional linkage and genome-wide association studies identify UGT1A1 as major gene for anti-atherogenic serum bilirubin levels - a Framingham Heart Study
    • Lin J-P, Schwaiger JP, Cupples LA et al. Conditional linkage and genome-wide association studies identify UGT1A1 as major gene for anti-atherogenic serum bilirubin levels - a Framingham Heart Study. Atherosclerosis 2009; 206: 228-33.
    • (2009) Atherosclerosis , vol.206 , pp. 228-233
    • Lin, J.-P.1    Schwaiger, J.P.2    Cupples, L.A.3
  • 178
    • 34548171994 scopus 로고    scopus 로고
    • A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease
    • Luke MM, Kane JP, Liu DM et al. A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease. Arterioscler Thromb Vasc Biol 2007; 27: 2030-6.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2030-2036
    • Luke, M.M.1    Kane, J.P.2    Liu, D.M.3
  • 179
    • 62649151842 scopus 로고    scopus 로고
    • Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy
    • Chasman DI, Shiffman D, Zee RY et al. Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy. Atherosclerosis 2009; 203: 371-6.
    • (2009) Atherosclerosis , vol.203 , pp. 371-376
    • Chasman, D.I.1    Shiffman, D.2    Zee, R.Y.3
  • 180
    • 67749114266 scopus 로고    scopus 로고
    • Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Mele in the Atherosclerosis Risk in Communities (ARIC) study
    • Shiffman D, Chasman DI, Ballantyne CM, Nambi V, Devlin JJ, Boerwinkle E. Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study. Thromb Haemost 2009; 102: 179-80.
    • (2009) Thromb Haemost , vol.102 , pp. 179-180
    • Shiffman, D.1    Chasman, D.I.2    Ballantyne, C.M.3    Nambi, V.4    Devlin, J.J.5    Boerwinkle, E.6
  • 181
    • 0033664654 scopus 로고    scopus 로고
    • High levels of Lp(a) with a small apo(a) isoform are associated with coronary artery disease in African American and White men
    • Paultre F, Pearson TA, Weil HF et al. High levels of Lp(a) with a small apo(a) isoform are associated with coronary artery disease in African American and White men. Arterioscler Thromb Vasc Biol 2000; 20: 2619-24.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2619-2624
    • Paultre, F.1    Pearson, T.A.2    Weil, H.F.3
  • 182
    • 0029019338 scopus 로고
    • No association between plasma lipoprotein(a) concentrations and the presence or absence of coronary atherosclerosis in African-Americans
    • Moliterno DJ, Jokinen EV, Miserez AR et al. No association between plasma lipoprotein(a) concentrations and the presence or absence of coronary atherosclerosis in African-Americans. Arterioscler Thromb Vasc Biol 1995; 15: 850-5.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 850-855
    • Moliterno, D.J.1    Jokinen, E.V.2    Miserez, A.R.3
  • 183
    • 84856101806 scopus 로고    scopus 로고
    • Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study
    • Virani SS, Brautbar A, Davis BC et al. Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation 2012; 125: 241-9.
    • (2012) Circulation , vol.125 , pp. 241-249
    • Virani, S.S.1    Brautbar, A.2    Davis, B.C.3
  • 184
    • 0037968849 scopus 로고    scopus 로고
    • Analysis of the apo(a) size polymorphism in Asian Indian populations: association with Lp(a) concentration and coronary heart disease
    • Geethanjali FS, Luthra K, Lingenhel A et al. Analysis of the apo(a) size polymorphism in Asian Indian populations: association with Lp(a) concentration and coronary heart disease. Atherosclerosis 2003; 169: 121-30.
    • (2003) Atherosclerosis , vol.169 , pp. 121-130
    • Geethanjali, F.S.1    Luthra, K.2    Lingenhel, A.3
  • 185
    • 16344394833 scopus 로고    scopus 로고
    • Lipoprotein(a) and apolipoprotein(a) isoforms. No association with coronary artery calcification in the dallas heart study
    • Guerra R, Yu Z, Marcovina S, Peshock R, Cohen JC, Hobbs HH. Lipoprotein(a) and apolipoprotein(a) isoforms. No association with coronary artery calcification in the dallas heart study. Circulation 2005; 111: 1471-9.
    • (2005) Circulation , vol.111 , pp. 1471-1479
    • Guerra, R.1    Yu, Z.2    Marcovina, S.3    Peshock, R.4    Cohen, J.C.5    Hobbs, H.H.6
  • 186
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science 1986; 232: 34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 187
    • 0031952385 scopus 로고    scopus 로고
    • Concentrations of the atherogenic Lp(a) are elevated in FH
    • Lingenhel A, Kraft H-G, Kotze M et al. Concentrations of the atherogenic Lp(a) are elevated in FH. Eur J Hum Genet 1998; 6: 50-60.
    • (1998) Eur J Hum Genet , vol.6 , pp. 50-60
    • Lingenhel, A.1    Kraft, H.-G.2    Kotze, M.3
  • 189
    • 0028936666 scopus 로고
    • The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans
    • Rader DJ, Mann WA, Cain W et al. The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans. J Clin Invest 1995; 95: 1403-8.
    • (1995) J Clin Invest , vol.95 , pp. 1403-1408
    • Rader, D.J.1    Mann, W.A.2    Cain, W.3
  • 190
    • 0030911569 scopus 로고    scopus 로고
    • Sib-pair analysis detects elevated Lp(a) levels and large variation of Lp(a) concentration in subjects with familiar defective ApoB
    • Van der Hoek YY, Lingenhel A, Kraft HG, Defesche JC, Kastelein JJP, Utermann G. Sib-pair analysis detects elevated Lp(a) levels and large variation of Lp(a) concentration in subjects with familiar defective ApoB. J Clin Invest 1997; 99: 2269-73.
    • (1997) J Clin Invest , vol.99 , pp. 2269-2273
    • Van der Hoek, Y.Y.1    Lingenhel, A.2    Kraft, H.G.3    Defesche, J.C.4    Kastelein, J.J.P.5    Utermann, G.6
  • 191
    • 0029042421 scopus 로고
    • Segregation analysis of plasma lipoprotein(a) levels in pedigrees with molecularly defined familial hypercholesterolemia
    • Friedlander Y, Leitersdorf E. Segregation analysis of plasma lipoprotein(a) levels in pedigrees with molecularly defined familial hypercholesterolemia. Genet Epidemiol 1995; 12: 129-43.
    • (1995) Genet Epidemiol , vol.12 , pp. 129-143
    • Friedlander, Y.1    Leitersdorf, E.2
  • 192
    • 0025358421 scopus 로고
    • Apolipoprotein(a) and ischaemic heart disease in familial hypercholesterolaemia
    • Wiklund O, Angelin B, Olofsson S-O et al. Apolipoprotein(a) and ischaemic heart disease in familial hypercholesterolaemia. Lancet 1990; 335: 1360-3.
    • (1990) Lancet , vol.335 , pp. 1360-1363
    • Wiklund, O.1    Angelin, B.2    Olofsson, S.-O.3
  • 193
    • 27444447294 scopus 로고    scopus 로고
    • Lipoprotein(a) is an independent risk factor for cardiovascular disease in heterozygous familial hypercholesterolemia
    • Holmes DT, Schick BA, Humphries KH, Frohlich J. Lipoprotein(a) is an independent risk factor for cardiovascular disease in heterozygous familial hypercholesterolemia. Clin Chem 2005; 51: 2067-73.
    • (2005) Clin Chem , vol.51 , pp. 2067-2073
    • Holmes, D.T.1    Schick, B.A.2    Humphries, K.H.3    Frohlich, J.4
  • 194
    • 9644287995 scopus 로고    scopus 로고
    • The contribution of classical risk factors to cardiovascular disease in familial hypercholesterolaemia: data in 2400 patients
    • Jansen AC, van Aalst-Cohen ES, Tanck MW et al. The contribution of classical risk factors to cardiovascular disease in familial hypercholesterolaemia: data in 2400 patients. J Intern Med 2004; 256: 482-90.
    • (2004) J Intern Med , vol.256 , pp. 482-490
    • Jansen, A.C.1    van Aalst-Cohen, E.S.2    Tanck, M.W.3
  • 195
    • 67651041086 scopus 로고    scopus 로고
    • Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review
    • Benn M. Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review. Atherosclerosis 2009; 206: 17-30.
    • (2009) Atherosclerosis , vol.206 , pp. 17-30
    • Benn, M.1
  • 196
    • 22644437126 scopus 로고    scopus 로고
    • Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review
    • Carlson LA. Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review. J Intern Med 2005; 258: 94-114.
    • (2005) J Intern Med , vol.258 , pp. 94-114
    • Carlson, L.A.1
  • 197
    • 0029859081 scopus 로고    scopus 로고
    • Neomycin inhibits secretion of apolipoprotein[a] by increasing retention on the hepatocyte cell surface
    • Lanford RE, Estlack L, White AL. Neomycin inhibits secretion of apolipoprotein[a] by increasing retention on the hepatocyte cell surface. J Lipid Res 1996; 37: 2055-64.
    • (1996) J Lipid Res , vol.37 , pp. 2055-2064
    • Lanford, R.E.1    Estlack, L.2    White, A.L.3
  • 198
    • 84867364520 scopus 로고    scopus 로고
    • Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice
    • doi: 10.1194/jlr.M029769 (in press).
    • Chennamsetty I, Kostner KM, Claudel T et al. Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice. J Lipid Res 2012; doi: 10.1194/jlr.M029769 (in press).
    • (2012) J Lipid Res
    • Chennamsetty, I.1    Kostner, K.M.2    Claudel, T.3
  • 199
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • Boden WE, Probstfield JL, Anderson T et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med 2011; 365: 2255-67.
    • (2011) N Engl J Med , vol.365 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 200
    • 78549235583 scopus 로고    scopus 로고
    • Safety of anacetrapib in patients with or at high risk for coronary heart disease
    • Cannon CP, Shah S, Dansky HM et al. Safety of anacetrapib in patients with or at high risk for coronary heart disease. N Engl J Med 2010; 363: 2406-15.
    • (2010) N Engl J Med , vol.363 , pp. 2406-2415
    • Cannon, C.P.1    Shah, S.2    Dansky, H.M.3
  • 201
    • 61549101898 scopus 로고    scopus 로고
    • Longitudinal cohort study on the effectiveness of lipid apheresis treatment to reduce high lipoprotein(a) levels and prevent major adverse coronary events
    • Jaeger BR, Richter Y, Nagel D et al. Longitudinal cohort study on the effectiveness of lipid apheresis treatment to reduce high lipoprotein(a) levels and prevent major adverse coronary events. Nat Clin Pract Cardiovasc Med 2009; 6: 229-39.
    • (2009) Nat Clin Pract Cardiovasc Med , vol.6 , pp. 229-239
    • Jaeger, B.R.1    Richter, Y.2    Nagel, D.3
  • 202
    • 78649390237 scopus 로고    scopus 로고
    • Lipoprotein apheresis
    • Thompson GR. Lipoprotein apheresis. Curr Opin Lipidol 2010; 21: 487-91.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 487-491
    • Thompson, G.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.