메뉴 건너뛰기




Volumn 49, Issue 10, 2008, Pages 2230-2239

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

Author keywords

Atherosclerosis; Cholesterol; Lipids; Lipoproteins; Oxidation

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN B100; LIPOPROTEIN A; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID; PHOSPHORYLCHOLINE;

EID: 59049086968     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800174-JLR200     Document Type: Article
Times cited : (288)

References (44)
  • 1
    • 47649091099 scopus 로고
    • A new serum type system in man - the LP system
    • Berg, K. 1963. A new serum type system in man - the LP system. Acta Pathol. Microbiol. Scand. 59: 369-382.
    • (1963) Acta Pathol. Microbiol. Scand , vol.59 , pp. 369-382
    • Berg, K.1
  • 2
    • 0032816711 scopus 로고    scopus 로고
    • Lipoprotein(a): Intrigues and insights
    • Hobbs, H. H., and A. L. White. 1999. Lipoprotein(a): intrigues and insights. Curr. Opin. Lipidol. 10: 225-236.
    • (1999) Curr. Opin. Lipidol , vol.10 , pp. 225-236
    • Hobbs, H.H.1    White, A.L.2
  • 4
    • 0024362630 scopus 로고
    • The mysteries of lipoprotein(a)
    • Utermann, G. 1989. The mysteries of lipoprotein(a). Science. 246: 904-910.
    • (1989) Science , vol.246 , pp. 904-910
    • Utermann, G.1
  • 5
  • 6
    • 10644264549 scopus 로고    scopus 로고
    • Lipoprotein(a): An elusive cardiovascular risk factor
    • Berglund, L., and R. Ramakrishnan. 2004. Lipoprotein(a): An elusive cardiovascular risk factor. Arterioscler. Thromb. Vasc. Biol. 24: 2219-2226.
    • (2004) Arterioscler. Thromb. Vasc. Biol , vol.24 , pp. 2219-2226
    • Berglund, L.1    Ramakrishnan, R.2
  • 7
    • 0034609562 scopus 로고    scopus 로고
    • Lipoprotein(a) and coronary artery disease. Metaanalysis of prospective studies
    • Danesh, J., R. Collins, and R. Peto. 2000. Lipoprotein(a) and coronary artery disease. Metaanalysis of prospective studies. Circulation. 102: 1082-1085.
    • (2000) Circulation , vol.102 , pp. 1082-1085
    • Danesh, J.1    Collins, R.2    Peto, R.3
  • 9
    • 33748904095 scopus 로고    scopus 로고
    • Lipoprotein (a), measured with an assay independent of apolipoprotein(a) isoform size, and risk of future cardiovascular events among initially healthy women
    • Suk, D. J., N. Rifai, J. E. Buring, and P. M. Ridker. 2006. Lipoprotein (a), measured with an assay independent of apolipoprotein(a) isoform size, and risk of future cardiovascular events among initially healthy women. J. Am. Med. Assoc. 296: 1363-1370.
    • (2006) J. Am. Med. Assoc , vol.296 , pp. 1363-1370
    • Suk, D.J.1    Rifai, N.2    Buring, J.E.3    Ridker, P.M.4
  • 11
    • 0035892139 scopus 로고    scopus 로고
    • Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis
    • Caplice, N. M., C. Panetta, T. E. Peterson, L. S. Kleppe, C. S. Mueske, G. M. Kostner, G. J. Broze, Jr., and R. D. Simari. 2001. Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis. Blood. 98: 2980-2987.
    • (2001) Blood , vol.98 , pp. 2980-2987
    • Caplice, N.M.1    Panetta, C.2    Peterson, T.E.3    Kleppe, L.S.4    Mueske, C.S.5    Kostner, G.M.6    Broze Jr., G.J.7    Simari, R.D.8
  • 12
    • 0037419857 scopus 로고    scopus 로고
    • Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes
    • Tsimikas, S., C. Bergmark, R. W. Beyer, R. Patel, J. Pattison, E. Miller, J. Juliano, and J. L. Witztum. 2003. Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes. J. Am. Coll. Cardiol. 41: 360-370.
    • (2003) J. Am. Coll. Cardiol , vol.41 , pp. 360-370
    • Tsimikas, S.1    Bergmark, C.2    Beyer, R.W.3    Patel, R.4    Pattison, J.5    Miller, E.6    Juliano, J.7    Witztum, J.L.8
  • 13
    • 9144233520 scopus 로고    scopus 로고
    • Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a)
    • Edelstein, C., D. Pfaffinger, J. Hinman, E. Miller, G. Lipkind, S. Tsimikas, C. Bergmark, G. S. Getz, J. L. Witztum, and A. M. Scanu. 2003. Lysine-phosphatidylcholine adducts in kringle V impart unique immunological and potential pro-inflammatory properties to human apolipoprotein(a). J. Biol. Chem. 278: 52841-52847.
    • (2003) J. Biol. Chem , vol.278 , pp. 52841-52847
    • Edelstein, C.1    Pfaffinger, D.2    Hinman, J.3    Miller, E.4    Lipkind, G.5    Tsimikas, S.6    Bergmark, C.7    Getz, G.S.8    Witztum, J.L.9    Scanu, A.M.10
  • 15
    • 4544261604 scopus 로고    scopus 로고
    • Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): Short-term and long-term immunologic responses to oxidized low-density lipoprotein
    • Tsimikas, S., H. K. Lau, K. R. Han, B. Shortal, E. R. Miller, A. Segev, L. K. Curtiss, J. L. Witztum, and B. H. Strauss. 2004. Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein. Circulation. 109: 3164-3170.
    • (2004) Circulation , vol.109 , pp. 3164-3170
    • Tsimikas, S.1    Lau, H.K.2    Han, K.R.3    Shortal, B.4    Miller, E.R.5    Segev, A.6    Curtiss, L.K.7    Witztum, J.L.8    Strauss, B.H.9
  • 16
    • 4544346640 scopus 로고    scopus 로고
    • High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial
    • Tsimikas, S., J. L. Witztum, E. R. Miller, W. J. Sasiela, M. Szarek, A. G. Olsson, and G. G. Schwartz. 2004. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation. 110: 1406-1412.
    • (2004) Circulation , vol.110 , pp. 1406-1412
    • Tsimikas, S.1    Witztum, J.L.2    Miller, E.R.3    Sasiela, W.J.4    Szarek, M.5    Olsson, A.G.6    Schwartz, G.G.7
  • 18
    • 33646902155 scopus 로고    scopus 로고
    • Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: Five-year prospective results fromthe Bruneck study
    • Tsimikas, S., S. Kiechl, J. Willeit, M. Mayr, E. R. Miller, F. Kronenberg, Q. Xu, C. Bergmark, S. Weger, F. Oberhollenzer, et al. 2006. Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results fromthe Bruneck study. J. Am. Coll. Cardiol. 47: 2219-2228.
    • (2006) J. Am. Coll. Cardiol , vol.47 , pp. 2219-2228
    • Tsimikas, S.1    Kiechl, S.2    Willeit, J.3    Mayr, M.4    Miller, E.R.5    Kronenberg, F.6    Xu, Q.7    Bergmark, C.8    Weger, S.9    Oberhollenzer, F.10
  • 20
    • 0031409345 scopus 로고    scopus 로고
    • Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study
    • Berg, K., G. Dahlen, B. Christophersen, T. Cook, J. Kjekshus, and T. Pedersen. 1997. Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study. Clin. Genet. 52: 254-261.
    • (1997) Clin. Genet , vol.52 , pp. 254-261
    • Berg, K.1    Dahlen, G.2    Christophersen, B.3    Cook, T.4    Kjekshus, J.5    Pedersen, T.6
  • 21
    • 0026352897 scopus 로고
    • Lp(a) lipoprotein level and longevity
    • Berg, K., and O. C. Ro. 1991. Lp(a) lipoprotein level and longevity. Ann. Genet. 34: 264-269.
    • (1991) Ann. Genet , vol.34 , pp. 264-269
    • Berg, K.1    Ro, O.C.2
  • 22
    • 0030769127 scopus 로고    scopus 로고
    • Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix
    • Pillarisetti, S., L. Paka, J. C. Obunike, L. Berglund, and I. J. Goldberg. 1997. Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix. J. Clin. Invest. 100: 867-874.
    • (1997) J. Clin. Invest , vol.100 , pp. 867-874
    • Pillarisetti, S.1    Paka, L.2    Obunike, J.C.3    Berglund, L.4    Goldberg, I.J.5
  • 24
    • 0037896283 scopus 로고    scopus 로고
    • Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins
    • Hõrkkõ, S., D. A. Bird, E. Miller, H. Itabe, N. Leitinger, G. Subbanagounder, J. A. Berliner, P. Friedman, E. A. Dennis, L. K. Curtiss, et al. 1999. Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. J. Clin. Invest. 103: 117-128.
    • (1999) J. Clin. Invest , vol.103 , pp. 117-128
    • Hõrkkõ, S.1    Bird, D.A.2    Miller, E.3    Itabe, H.4    Leitinger, N.5    Subbanagounder, G.6    Berliner, J.A.7    Friedman, P.8    Dennis, E.A.9    Curtiss, L.K.10
  • 25
    • 0036510381 scopus 로고    scopus 로고
    • Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids: Importance of Schiff base formation and Aldol condensation
    • Friedman, P., S. Hörkkö, D. Steinberg, J. L. Witztum, and E. A. Dennis. 2001. Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids: importance of Schiff base formation and Aldol condensation. J. Biol. Chem. 277: 7010-7020.
    • (2001) J. Biol. Chem , vol.277 , pp. 7010-7020
    • Friedman, P.1    Hörkkö, S.2    Steinberg, D.3    Witztum, J.L.4    Dennis, E.A.5
  • 26
    • 0021969806 scopus 로고
    • Cholestyramine-induced changes in low density lipoprotein composition and metabolism. I. Studies in the guinea pig
    • Witztum, J. L., S. G. Young, R. L. Elam, T. E. Carew, and M. Fisher. 1985. Cholestyramine-induced changes in low density lipoprotein composition and metabolism. I. Studies in the guinea pig. J. Lipid Res. 26: 92-103.
    • (1985) J. Lipid Res , vol.26 , pp. 92-103
    • Witztum, J.L.1    Young, S.G.2    Elam, R.L.3    Carew, T.E.4    Fisher, M.5
  • 27
    • 0019486232 scopus 로고
    • A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum
    • Chapman,M. J., S. Goldstein, D.Lagrange, and P. M. Laplaud. 1981. A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum. J. Lipid Res. 22: 339-358.
    • (1981) J. Lipid Res , vol.22 , pp. 339-358
    • Chapman, M.J.1    Goldstein, S.2    Lagrange, D.3    Laplaud, P.M.4
  • 30
    • 0343238361 scopus 로고    scopus 로고
    • Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors
    • Gillotte, K. L., S. Horkko, J. L. Witztum, and D. Steinberg. 2000. Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors. J. Lipid Res. 41: 824-833.
    • (2000) J. Lipid Res , vol.41 , pp. 824-833
    • Gillotte, K.L.1    Horkko, S.2    Witztum, J.L.3    Steinberg, D.4
  • 32
    • 33847659127 scopus 로고    scopus 로고
    • Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: A potential biomarker of early atherosclerosis regression
    • Tsimikas, S., M. Aikawa, F. J. Miller, Jr., E. R. Miller, M. Torzewski, S. R. Lentz, C. Bergmark, D. D. Heistad, P. Libby, and J. L. Witztum. 2007. Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid-lowering: a potential biomarker of early atherosclerosis regression. Arterioscler. Thromb. Vasc. Biol. 27: 175-181.
    • (2007) Arterioscler. Thromb. Vasc. Biol , vol.27 , pp. 175-181
    • Tsimikas, S.1    Aikawa, M.2    Miller Jr., F.J.3    Miller, E.R.4    Torzewski, M.5    Lentz, S.R.6    Bergmark, C.7    Heistad, D.D.8    Libby, P.9    Witztum, J.L.10
  • 33
    • 3042613703 scopus 로고    scopus 로고
    • Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice
    • Reardon, C. A., E. R. Miller, L. Blachowicz, J. Lukens, C. J. Binder, J. L. Witztum, and G. S. Getz. 2004. Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice. J. Lipid Res. 45: 1347-1354.
    • (2004) J. Lipid Res , vol.45 , pp. 1347-1354
    • Reardon, C.A.1    Miller, E.R.2    Blachowicz, L.3    Lukens, J.4    Binder, C.J.5    Witztum, J.L.6    Getz, G.S.7
  • 37
    • 17944387960 scopus 로고    scopus 로고
    • Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/ endothelial interactions and evidence for their presence in vivo
    • Watson, A. D., N. Leitinger, M. Navab, K. F. Faull, S. Hörkkö, J. L. Witztum, W. Palinski, D. Schwenke, R. Salomon, W. Sha, et al. 1997. Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/ endothelial interactions and evidence for their presence in vivo. J. Biol. Chem. 272: 13597-13607.
    • (1997) J. Biol. Chem , vol.272 , pp. 13597-13607
    • Watson, A.D.1    Leitinger, N.2    Navab, M.3    Faull, K.F.4    Hörkkö, S.5    Witztum, J.L.6    Palinski, W.7    Schwenke, D.8    Salomon, R.9    Sha, W.10
  • 38
    • 0037064036 scopus 로고    scopus 로고
    • A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions
    • Podrez, E. A., E. Poliakov, Z. Shen, R. Zhang, Y. Deng, M. Sun, P. J. Finton, L. Shan, M. Febbraio, D. P. Hajjar, et al. 2002. A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. J. Biol. Chem. 277: 38517-38523.
    • (2002) J. Biol. Chem , vol.277 , pp. 38517-38523
    • Podrez, E.A.1    Poliakov, E.2    Shen, Z.3    Zhang, R.4    Deng, Y.5    Sun, M.6    Finton, P.J.7    Shan, L.8    Febbraio, M.9    Hajjar, D.P.10
  • 40
    • 34547159770 scopus 로고    scopus 로고
    • Promise of immune modulation to inhibit atherogenesis
    • Binder, C. J., K. Hartvigsen, and J. L. Witztum. 2007. Promise of immune modulation to inhibit atherogenesis. J. Am. Coll. Cardiol. 50: 547-550.
    • (2007) J. Am. Coll. Cardiol , vol.50 , pp. 547-550
    • Binder, C.J.1    Hartvigsen, K.2    Witztum, J.L.3
  • 41
    • 0032989435 scopus 로고    scopus 로고
    • Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition
    • Chang, M. K., C. Bergmark, A. Laurila, S. Hörkkö, K. H. Han, P. Friedman, E. A. Dennis, and J. L. Witztum. 1999. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition. Proc. Natl. Acad. Sci. USA. 96: 6353-6358.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6353-6358
    • Chang, M.K.1    Bergmark, C.2    Laurila, A.3    Hörkkö, S.4    Han, K.H.5    Friedman, P.6    Dennis, E.A.7    Witztum, J.L.8
  • 42
    • 0036141870 scopus 로고    scopus 로고
    • Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions
    • Huber, J., A. Vales, G. Mitulovic, M. Blumer, R. Schmid, J. L. Witztum, B. R. Binder, and N. Leitinger. 2002. Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions. Arterioscler. Thromb. Vasc. Biol. 22: 101-107.
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 101-107
    • Huber, J.1    Vales, A.2    Mitulovic, G.3    Blumer, M.4    Schmid, R.5    Witztum, J.L.6    Binder, B.R.7    Leitinger, N.8
  • 43
    • 0029620828 scopus 로고
    • Enhanced association of platelet-activating factor acetylhydrolase with lipoprotein (a) in comparison with low density lipoprotein
    • Blencowe, C., A. Hermetter, G. M. Kostner, and H. P. Deigner. 1995. Enhanced association of platelet-activating factor acetylhydrolase with lipoprotein (a) in comparison with low density lipoprotein. J. Biol. Chem. 270: 31151-31157.
    • (1995) J. Biol. Chem , vol.270 , pp. 31151-31157
    • Blencowe, C.1    Hermetter, A.2    Kostner, G.M.3    Deigner, H.P.4
  • 44
    • 0030599042 scopus 로고    scopus 로고
    • PAF-acetylhydrolase activity of Lp(a) before and during Cu(2+)-induced oxidative modification in vitro
    • Karabina, S. A., M. C. Elisaf, J. Goudevenos, K. C. Siamopoulos, D. Sideris, and A. D. Tselepis. 1996. PAF-acetylhydrolase activity of Lp(a) before and during Cu(2+)-induced oxidative modification in vitro. Atherosclerosis. 125: 121-134.
    • (1996) Atherosclerosis , vol.125 , pp. 121-134
    • Karabina, S.A.1    Elisaf, M.C.2    Goudevenos, J.3    Siamopoulos, K.C.4    Sideris, D.5    Tselepis, A.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.