메뉴 건너뛰기




Volumn 32, Issue 3, 2012, Pages 810-814

Endogenous estrogens lower plasma PCSK9 and LDL cholesterol but not Lp(a) or bile acid synthesis in women

Author keywords

circulating PCSK9; hormonal regulation; lipids; lipoproteins; metabolism

Indexed keywords

APOLIPOPROTEIN B; BILE ACID; CAMPESTEROL; FIBROBLAST GROWTH FACTOR 21; GROWTH HORMONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROPROTEINCONVERTASE SUBTILISIN KEXIN TYPE 9; PROTEIN; SOMATOMEDIN C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 84857652540     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.242461     Document Type: Article
Times cited : (80)

References (39)
  • 1
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Executive summary of the third report of The National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285:2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 2
    • 0018918106 scopus 로고
    • Lipoprotein-cholesterol distributions in selected North American populations: The Lipid Research Clinics Program Prevalence Study
    • Heiss G, Tamir I, Davis CE, Tyroler HA, Rifkand BM, Schonfeld G, Jacobs D, Frantz ID Jr. Lipoprotein-cholesterol distributions in selected North American populations: the lipid research clinics program prevalence study. Circulation. 1980;61:302-315. (Pubitemid 10214988)
    • (1980) Circulation , vol.61 , Issue.2 , pp. 302-315
    • Heiss, G.1    Tamir, I.2    Davis, C.E.3
  • 4
    • 81855201805 scopus 로고    scopus 로고
    • Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19
    • Galman C, Angelin B, Rudling M. Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19. J Intern Med. 2011;270: 580-588.
    • (2011) J Intern Med , vol.270 , pp. 580-588
    • Galman, C.1    Angelin, B.2    Rudling, M.3
  • 5
    • 0024450180 scopus 로고
    • Estrogen-induced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma
    • Henriksson P, Einarsson K, Eriksson A, Kelter U, Angelin B. Estrogeninduced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma. J Clin Invest. 1989;84:811-816. (Pubitemid 19228351)
    • (1989) Journal of Clinical Investigation , vol.84 , Issue.3 , pp. 811-816
    • Henriksson, P.1    Einarsson, K.2    Eriksson, A.3    Kelter, U.4    Angelin, B.5
  • 6
    • 0020510646 scopus 로고
    • The effects of estrogen administration on plasma lipoprotein metabolism in premenopausal females
    • Schaefer EJ, Foster DM, Zech LA, Lindgren FT, Brewer HB Jr, Levy RI. The effects of estrogen administration on plasma lipoprotein metabolism in premenopausal females. J Clin Endocrinol Metab. 1983;57:262-267. (Pubitemid 13032472)
    • (1983) Journal of Clinical Endocrinology and Metabolism , vol.57 , Issue.2 , pp. 262-267
    • Schaefer, E.J.1    Foster, D.M.2    Zech, L.A.3
  • 7
    • 0026072558 scopus 로고
    • Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins
    • Walsh BW, Schiff I, Rosner B, Greenberg L, Ravnikar V, Sacks FM. Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. N Engl J Med. 1991;325: 1196-1204.
    • (1991) N Engl J Med , vol.325 , pp. 1196-1204
    • Walsh, B.W.1    Schiff, I.2    Rosner, B.3    Greenberg, L.4    Ravnikar, V.5    Sacks, F.M.6
  • 8
    • 0026628106 scopus 로고
    • Hormonal regulation of serum Lp (a) levels. Opposite effects after estrogen treatment and orchidectomy in males with prostatic carcinoma
    • Henriksson P, Angelin B, Berglund L. Hormonal regulation of serum Lp (a) levels. Opposite effects after estrogen treatment and orchidectomy in males with prostatic carcinoma. J Clin Invest. 1992;89:1166-1171.
    • (1992) J Clin Invest , vol.89 , pp. 1166-1171
    • Henriksson, P.1    Angelin, B.2    Berglund, L.3
  • 9
    • 0024418329 scopus 로고
    • Effects of estrogen on low density lipoprotein metabolism in males. Short-term and long-term studies during hormonal treatment of prostatic carcinoma
    • Eriksson M, Berglund L, Rudling M, Henriksson P, Angelin B. Effects of estrogen on low density lipoprotein metabolism in males. Short-term and long-term studies during hormonal treatment of prostatic carcinoma. J Clin Invest. 1989;84:802-810. (Pubitemid 19228350)
    • (1989) Journal of Clinical Investigation , vol.84 , Issue.3 , pp. 802-810
    • Eriksson, M.1    Berglund, L.2    Rudling, M.3    Henriksson, P.4    Angelin, B.5
  • 10
    • 0017719024 scopus 로고
    • Atherosclerosis: The low-density lipoprotein receptor hypothesis
    • DOI 10.1016/0026-0495(77)90119-6
    • Goldstein JL, Brown MS. Atherosclerosis: the low-density lipoprotein receptor hypothesis. Metabolism. 1977;26:1257-1275. (Pubitemid 8210421)
    • (1977) Metabolism: Clinical and Experimental , vol.26 , Issue.11 , pp. 1257-1275
    • Goldstein, J.L.1    Brown, M.S.2
  • 12
    • 0019174823 scopus 로고
    • The estradiol-stimulated lipoprotein receptor of rat liver, a binding site that mediates the uptake of rat lipoproteins containing apoproteins B and E
    • Windler EE, Kovanen PT, Chao YS, Brown MS, Havel RJ, Goldstein JL. The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E. J Biol Chem. 1980;255:10464-10471. (Pubitemid 11219979)
    • (1980) Journal of Biological Chemistry , vol.255 , Issue.21 , pp. 10464-10471
    • Windler, E.E.T.1    Kovanen, P.T.2    Chao, Y.S.3
  • 13
    • 0027301849 scopus 로고
    • In vivo regulation of low-density lipoprotein receptors by estrogen differs at the post-transcriptional level in rat and mouse
    • Srivastava RA, Baumann D, Schonfeld G. In vivo regulation of lowdensity lipoprotein receptors by estrogen differs at the post-transcriptional level in rat and mouse. Eur J Biochem. 1993;216:527-538. (Pubitemid 23276300)
    • (1993) European Journal of Biochemistry , vol.216 , Issue.2 , pp. 527-538
    • Srivastava, R.A.K.1    Baumann, D.2    Schonfeld, G.3
  • 14
    • 67649842300 scopus 로고    scopus 로고
    • Importance of proprotein convertase subtilisin/kexin type 9 in the hormonal and dietary regulation of rat liver low-density lipoprotein receptors
    • Persson L, Galman C, Angelin B, Rudling M. Importance of proprotein convertase subtilisin/kexin type 9 in the hormonal and dietary regulation of rat liver low-density lipoprotein receptors. Endocrinology. 2009;150: 1140-1146.
    • (2009) Endocrinology , vol.150 , pp. 1140-1146
    • Persson, L.1    Galman, C.2    Angelin, B.3    Rudling, M.4
  • 15
    • 0027233758 scopus 로고
    • Stimulation of rat hepatic low density lipoprotein receptors by glucagon. Evidence of a novel regulatory mechanism in vivo
    • Rudling M, Angelin B. Stimulation of rat hepatic low density lipoprotein receptors by glucagon. Evidence of a novel regulatory mechanism in vivo. J Clin Invest. 1993;91:2796-2805. (Pubitemid 23182538)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.6 , pp. 2796-2805
    • Rudling, M.1    Angelin, B.2
  • 16
    • 33644909215 scopus 로고    scopus 로고
    • Lipoprotein profiles in plasma and interstitial fluid analyzed with an automated gel-filtration system
    • Parini P, Johansson L, Broijersen A, Angelin B, Rudling M. Lipoprotein profiles in plasma and interstitial fluid analyzed with an automated gel-filtration system. Eur J Clin Invest. 2006;36:98-104.
    • (2006) Eur J Clin Invest , vol.36 , pp. 98-104
    • Parini, P.1    Johansson, L.2    Broijersen, A.3    Angelin, B.4    Rudling, M.5
  • 17
    • 0023737126 scopus 로고
    • Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans
    • Kempen HJ, Glatz JF, Gevers Leuven JA, van der Voort HA, Katan MB. Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans. J Lipid Res. 1988;29:1149-1155.
    • (1988) J Lipid Res , vol.29 , pp. 1149-1155
    • Kempen, H.J.1    Glatz, J.F.2    Gevers Leuven, J.A.3    Van Der Voort, H.A.4    Katan, M.B.5
  • 18
    • 0142074212 scopus 로고    scopus 로고
    • Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood
    • Galman C, Arvidsson I, Angelin B, Rudling M. Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood. J Lipid Res. 2003;44:859-866.
    • (2003) J Lipid Res , vol.44 , pp. 859-866
    • Galman, C.1    Arvidsson, I.2    Angelin, B.3    Rudling, M.4
  • 19
    • 10744220956 scopus 로고    scopus 로고
    • Bile acid synthesis is increased in chilean hispanics with gallstones and in gallstone high-risk mapuche indians
    • DOI 10.1053/j.gastro.2003.12.009
    • Galman C, Miquel JF, Perez RM, Einarsson C, Stahle L, Marshall G, Nervi F, Rudling M. Bile acid synthesis is increased in Chilean Hispanics with gallstones and in gallstone high-risk Mapuche Indians. Gastroenterology. 2004;126:741-748. (Pubitemid 38298322)
    • (2004) Gastroenterology , vol.126 , Issue.3 , pp. 741-748
    • Galman, C.1    Miquel, J.F.2    Perez, R.M.3    Einarsson, C.4    Stahle, L.5    Marshall, G.6    Nervi, F.7    Rudling, M.8
  • 20
    • 0025156823 scopus 로고
    • Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population
    • Miettinen TA, Tilvis RS, Kesaniemi YA. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol. 1990; 131:20-31. (Pubitemid 20014696)
    • (1990) American Journal of Epidemiology , vol.131 , Issue.1 , pp. 20-31
    • Miettinen, T.A.1    Tilvis, R.S.2    Kesaniemi, Y.A.3
  • 21
    • 0034019728 scopus 로고    scopus 로고
    • Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: Relation to basal serum cholestanol
    • Miettinen TA, Strandberg TE, Gylling H. Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: relation to basal serum cholestanol. Arterioscler Thromb Vasc Biol. 2000;20:1340-1346. (Pubitemid 30262937)
    • (2000) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.20 , Issue.5 , pp. 1340-1346
    • Miettinen, T.A.1    Strandberg, T.E.2    Gylling, H.3
  • 22
    • 0013818657 scopus 로고
    • Effects of estrogen and sex difference on secretion of human growth hormone
    • Frantz AG, Rabkin MT. Effects of estrogen and sex difference on secretion of human growth hormone. J Clin Endocrinol Metab. 1965;25: 1470-1480.
    • (1965) J Clin Endocrinol Metab , vol.25 , pp. 1470-1480
    • Frantz, A.G.1    Rabkin, M.T.2
  • 23
    • 0022494612 scopus 로고
    • Regulation of growth hormone and somatomedin-C secretion in postmenopausal women: Effect of physiological estrogen replacement
    • Dawson-Hughes B, Stern D, Goldman J, Reichlin S. Regulation of growth hormone and somatomedin-C secretion in postmenopausal women: effect of physiological estrogen replacement. J Clin Endocrinol Metab. 1986;63:424-432. (Pubitemid 16035693)
    • (1986) Journal of Clinical Endocrinology and Metabolism , vol.63 , Issue.2 , pp. 424-432
    • Dawson-Hughes, B.1    Stern, D.2    Goldman, J.3    Reichlin, S.4
  • 24
    • 0035052713 scopus 로고    scopus 로고
    • Requirement of Sp1 and estrogen receptor α interaction in 17β-estradiol-mediated transcriptional activation of the low density lipoprotein receptor gene expression
    • DOI 10.1210/en.142.4.1546
    • Li C, Briggs MR, Ahlborn TE, Kraemer FB, Liu J. Requirement of Sp1 and estrogen receptor alpha interaction in 17beta-estradiol-mediated transcriptional activation of the low density lipoprotein receptor gene expression. Endocrinology. 2001;142:1546-1553. (Pubitemid 32299683)
    • (2001) Endocrinology , vol.142 , Issue.4 , pp. 1546-1553
    • Li, C.1    Briggs, M.R.2    Ahlborn, T.E.3    Kraemer, F.B.4    Liu, J.5
  • 25
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med. 2006;354:1264-1272.
    • (2006) N Engl J Med , vol.354 , pp. 1264-1272
    • Cohen, J.C.1    Boerwinkle, E.2    Mosley Jr., T.H.3    Hobbs, H.H.4
  • 29
    • 0344236142 scopus 로고    scopus 로고
    • Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice
    • DOI 10.1194/jlr.M300203-JLR200
    • Maxwell KN, Soccio RE, Duncan EM, Sehayek E, Breslow JL. Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice. J Lipid Res. 2003;44:2109-2119. (Pubitemid 37509626)
    • (2003) Journal of Lipid Research , vol.44 , Issue.11 , pp. 2109-2119
    • Maxwell, K.N.1    Soccio, R.E.2    Duncan, E.M.3    Sehayek, E.4    Breslow, J.L.5
  • 31
    • 0242288750 scopus 로고    scopus 로고
    • Cardiovascular endocrinology 4: Low-Density Lipoprotein Size and Cardiovascular Disease: A Reappraisal
    • DOI 10.1210/jc.2003-030636
    • Sacks FM, Campos H. Clinical review 163: Cardiovascular endocrinology: Low-density lipoprotein size and cardiovascular disease: a reappraisal. J Clin Endocrinol Metab. 2003;88:4525-4532. (Pubitemid 37357487)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.10 , pp. 4525-4532
    • Sacks, F.M.1    Campos, H.2
  • 33
    • 0023036713 scopus 로고
    • Stimulation of growth hormone release and synthesis by estrogens in rat anterior pituitary cells in culture
    • Simard J, Hubert JF, Hosseinzadeh T, Labrie F. Stimulation of growth hormone release and synthesis by estrogens in rat anterior pituitary cells in culture. Endocrinology. 1986;119:2004-2011. (Pubitemid 17171377)
    • (1986) Endocrinology , vol.119 , Issue.5 , pp. 2004-2011
    • Simard, J.1    Hubert, J.-F.2    Hosseinzadeh, T.3    Labrie, F.4
  • 36
    • 85003112639 scopus 로고
    • Growth hormone treatment does not alter biliary lipid metabolism in healthy adult men
    • Olivecrona H, Ericsson S, Angelin B. Growth hormone treatment does not alter biliary lipid metabolism in healthy adult men. J Clin Endocrinol Metab. 1995;80:1113-1117.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1113-1117
    • Olivecrona, H.1    Ericsson, S.2    Angelin, B.3
  • 38
    • 18844375867 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy on insulin-like growth factor (IGF)-I, IGF-II and IGF binding protein (IGFBP)-1 to IGFBP-4: Implications for cardiovascular risk
    • DOI 10.1080/09513590400027406
    • Heald A, Kaushal K, Anderson S, Redpath M, Durrington PN, Selby PL, Gibson MJ. Effects of hormone replacement therapy on insulin-like growth factor (IGF)-I, IGF-II and IGF binding protein (IGFBP)-1 to IGFBP-4: implications for cardiovascular risk. Gynecol Endocrinol. 2005;20:176-182. (Pubitemid 40694924)
    • (2005) Gynecological Endocrinology , vol.20 , Issue.3 , pp. 176-182
    • Heald, A.1    Kaushal, K.2    Anderson, S.3    Redpath, M.4    Durrington, P.N.5    Selby, P.L.6    Gibson, M.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.