메뉴 건너뛰기




Volumn 16, Issue 11, 2008, Pages 1372-1379

Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A; GENOMIC DNA; LIPOPROTEIN; TISSUE FACTOR PATHWAY INHIBITOR;

EID: 54549096882     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2008.114     Document Type: Article
Times cited : (24)

References (33)
  • 1
    • 0032542389 scopus 로고    scopus 로고
    • Lipoprotein(a) as a risk factor for coronary artery disease
    • Marcovina SM, Koschinsky ML: Lipoprotein(a) as a risk factor for coronary artery disease. Am J Cardiol 1998; 82: 57U-66U.
    • (1998) Am J Cardiol , vol.82
    • Marcovina, S.M.1    Koschinsky, M.L.2
  • 2
    • 0034609562 scopus 로고    scopus 로고
    • Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies
    • Danesh J, Collins R, Peto R: Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies. Circulation 2000; 102: 1082-1085.
    • (2000) Circulation , vol.102 , pp. 1082-1085
    • Danesh, J.1    Collins, R.2    Peto, R.3
  • 3
    • 33845411733 scopus 로고    scopus 로고
    • Novel insights into Lp(a) physiology and pathogenicity: More questions than answers?
    • Koschinsky ML: Novel insights into Lp(a) physiology and pathogenicity: more questions than answers? Cardiovasc Hematol Disord Drug Targets 2006; 6: 267-278.
    • (2006) Cardiovasc Hematol Disord Drug Targets , vol.6 , pp. 267-278
    • Koschinsky, M.L.1
  • 4
  • 5
    • 0024543611 scopus 로고
    • Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation
    • Boerwinkle E, Menzel HJ, Kraft HG, Utermann G: Genetics of the quantitative Lp(a) lipoprotein trait. III. Contribution of Lp(a) glycoprotein phenotypes to normal lipid variation. Hum Genet 1989; 82: 73-78.
    • (1989) Hum Genet , vol.82 , pp. 73-78
    • Boerwinkle, E.1    Menzel, H.J.2    Kraft, H.G.3    Utermann, G.4
  • 6
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH: Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest 1992; 90 52-60.
    • (1992) J Clin Invest , vol.90 , pp. 52-60
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3    Lackner, C.4    Chiesa, G.5    Hobbs, H.H.6
  • 7
    • 0033664654 scopus 로고    scopus 로고
    • High levels of Lp(a) with a small apo(a) isoform are associated with coronary artery disease in African American and white men
    • Paultre F, Pearson TA, Weil HF et al: High levels of Lp(a) with a small apo(a) isoform are associated with coronary artery disease in African American and white men. Arterioscler Thromb Vasc Biol 2000; 20: 2619-2624.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2619-2624
    • Paultre, F.1    Pearson, T.A.2    Weil, H.F.3
  • 8
    • 54549093194 scopus 로고    scopus 로고
    • Tsimikas S, Tsironis LD, Tselepis AD: New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease. Arterioscler Thromb Vasc Biol 2007 and N Engl J Med 2005; 353: 46-57.
    • Tsimikas S, Tsironis LD, Tselepis AD: New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease. Arterioscler Thromb Vasc Biol 2007 and N Engl J Med 2005; 353: 46-57.
  • 9
    • 34548171994 scopus 로고    scopus 로고
    • A polymorphism in the proteaselike domain of apolipoprotein(a) is associated with severe coronary artery disease
    • Luke MM, Kane JP, Liu DM et al: A polymorphism in the proteaselike domain of apolipoprotein(a) is associated with severe coronary artery disease. Arterioscler Thromb Vasc Biol 2007; 27: 2030-2036.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2030-2036
    • Luke, M.M.1    Kane, J.P.2    Liu, D.M.3
  • 10
    • 33846168084 scopus 로고    scopus 로고
    • Chretien JP, Coresh J, Berthier-Schaad Y et al: Three single- nucleotide polymorphisms in LPA account for most of the increase in lipoprotein(a) level elevation in African Americans compared with European Americans. J Med Genet 2006; 43: 917-923.
    • Chretien JP, Coresh J, Berthier-Schaad Y et al: Three single- nucleotide polymorphisms in LPA account for most of the increase in lipoprotein(a) level elevation in African Americans compared with European Americans. J Med Genet 2006; 43: 917-923.
  • 11
    • 0035311403 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6-10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians
    • Ogorelkova M, Kraft HG, Ehnholm C, Utermann G: Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6-10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians. Hum Mol Genet 2001; 10: 815-824.
    • (2001) Hum Mol Genet , vol.10 , pp. 815-824
    • Ogorelkova, M.1    Kraft, H.G.2    Ehnholm, C.3    Utermann, G.4
  • 12
    • 10844258968 scopus 로고    scopus 로고
    • A common nonsense mutation in the repetitive Kringle IV-2 domain of human apolipoprotein(a) results in a truncated protein and low plasma Lp(a)
    • Parson W, Kraft HG, Niederstatter H et al: A common nonsense mutation in the repetitive Kringle IV-2 domain of human apolipoprotein(a) results in a truncated protein and low plasma Lp(a). Hum Mutat 2004; 24: 474-480.
    • (2004) Hum Mutat , vol.24 , pp. 474-480
    • Parson, W.1    Kraft, H.G.2    Niederstatter, H.3
  • 13
    • 33846315479 scopus 로고    scopus 로고
    • Multiple QTL influence the serum Lp(a) concentration: A genome-wide linkage screen in the PROCARDIS study
    • Barlera S, Specchia C, Farrall M et al: Multiple QTL influence the serum Lp(a) concentration: A genome-wide linkage screen in the PROCARDIS study. Eur J Hum Genet 2007; 15: 221-227.
    • (2007) Eur J Hum Genet , vol.15 , pp. 221-227
    • Barlera, S.1    Specchia, C.2    Farrall, M.3
  • 14
    • 18544372620 scopus 로고    scopus 로고
    • A comprehensive linkage analysis for myocardial infarction and its related risk factors
    • Broeckel U, Hengstenberg C, Mayer B et al: A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet 2002; 30: 210-214.
    • (2002) Nat Genet , vol.30 , pp. 210-214
    • Broeckel, U.1    Hengstenberg, C.2    Mayer, B.3
  • 15
    • 0142105891 scopus 로고    scopus 로고
    • Lack of genetic linkage evidence for a trans-acting factor having a large effect on plasma lipoprotein[a] levels in African Americans
    • Barkley RA, Brown AC, Hanis CL, Kardia SL, Turner ST, Boerwinkle E: Lack of genetic linkage evidence for a trans-acting factor having a large effect on plasma lipoprotein[a] levels in African Americans. J Lipid Res 2003; 44: 1301-1305.
    • (2003) J Lipid Res , vol.44 , pp. 1301-1305
    • Barkley, R.A.1    Brown, A.C.2    Hanis, C.L.3    Kardia, S.L.4    Turner, S.T.5    Boerwinkle, E.6
  • 16
    • 0034603799 scopus 로고    scopus 로고
    • Genetic determinants of hemostasis phenotypes in Spanish families
    • Souto JC, Almasy L, Borrell M et al: Genetic determinants of hemostasis phenotypes in Spanish families. Circulation 2000; 101: 1546-1551.
    • (2000) Circulation , vol.101 , pp. 1546-1551
    • Souto, J.C.1    Almasy, L.2    Borrell, M.3
  • 17
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 18
    • 18244384262 scopus 로고    scopus 로고
    • A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease
    • Soria JM, Almasy L, Souto JC et al: A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. Am J Hum Genet 2002; 70 567-574.
    • (2002) Am J Hum Genet , vol.70 , pp. 567-574
    • Soria, J.M.1    Almasy, L.2    Souto, J.C.3
  • 19
    • 0003555521 scopus 로고
    • PEDSYS: A pedigree data management sytem. User's manual
    • Tech. Rep. No. 2 San Antonio, Texas: Southwest Foundation for Biomedical Research
    • Dyke A: PEDSYS: a pedigree data management sytem. User's manual. Tech. Rep. No. 2 San Antonio, Texas: Southwest Foundation for Biomedical Research, 1995.
    • (1995)
    • Dyke, A.1
  • 20
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 1998; 62: 1198-1211.
    • (1998) Am J Hum Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 21
    • 0033358545 scopus 로고    scopus 로고
    • Testing the robustness of the likelihood-ratio test in a variance- component quantitative-trait loci-mapping procedure
    • Allison DB, Neale MC, Zannolli R, Schork NJ, Amos CI, Blangero J: Testing the robustness of the likelihood-ratio test in a variance- component quantitative-trait loci-mapping procedure. Am J Hum Genet 1999; 65: 531-544.
    • (1999) Am J Hum Genet , vol.65 , pp. 531-544
    • Allison, D.B.1    Neale, M.C.2    Zannolli, R.3    Schork, N.J.4    Amos, C.I.5    Blangero, J.6
  • 22
    • 0033820011 scopus 로고    scopus 로고
    • Robust LOD scores for variance component-based linkage analysis
    • Blangero J, Williams JT, Almasy L: Robust LOD scores for variance component-based linkage analysis. Genet Epidemiol 2000; 19: S8-14.
    • (2000) Genet Epidemiol , vol.19
    • Blangero, J.1    Williams, J.T.2    Almasy, L.3
  • 23
    • 0019920786 scopus 로고
    • Extensions to multivariate normal models for pedigree analysis
    • Hopper JL, Mathews JD: Extensions to multivariate normal models for pedigree analysis. Ann Hum Genet 1982; 46: 373-383.
    • (1982) Ann Hum Genet , vol.46 , pp. 373-383
    • Hopper, J.L.1    Mathews, J.D.2
  • 24
    • 0021297613 scopus 로고
    • Ascertainment and goodness of fit of variance component models for pedigree data
    • Boehnke M, Lange K: Ascertainment and goodness of fit of variance component models for pedigree data. Prog Clin Biol Res 1984; 147: 173-192.
    • (1984) Prog Clin Biol Res , vol.147 , pp. 173-192
    • Boehnke, M.1    Lange, K.2
  • 25
    • 0027487931 scopus 로고
    • Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent
    • Feingold E, Brown PO, Siegmund D: Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am J Hum Genet 1993; 53: 234-251.
    • (1993) Am J Hum Genet , vol.53 , pp. 234-251
    • Feingold, E.1    Brown, P.O.2    Siegmund, D.3
  • 26
    • 10244263487 scopus 로고    scopus 로고
    • Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study
    • Mitchell BD, Kammerer CM, Blangero J et al: Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study. Circulation 1996; 94: 2159-2170.
    • (1996) Circulation , vol.94 , pp. 2159-2170
    • Mitchell, B.D.1    Kammerer, C.M.2    Blangero, J.3
  • 27
    • 0034753277 scopus 로고    scopus 로고
    • The genetic dissection of complex traits in a founder population
    • Ober C, Abney M, McPeek MS: The genetic dissection of complex traits in a founder population. Am J Hum Genet 2001; 69: 1068-1079.
    • (2001) Am J Hum Genet , vol.69 , pp. 1068-1079
    • Ober, C.1    Abney, M.2    McPeek, M.S.3
  • 29
    • 0041877724 scopus 로고    scopus 로고
    • Two-locus linkage analysis applied to putative quantitative trait loci for lipoprotein(a) levels
    • Beekman M, Heijmans BT, Martin NG et al: Two-locus linkage analysis applied to putative quantitative trait loci for lipoprotein(a) levels. Twin Res 2003; 6: 322-324.
    • (2003) Twin Res , vol.6 , pp. 322-324
    • Beekman, M.1    Heijmans, B.T.2    Martin, N.G.3
  • 30
    • 0035892139 scopus 로고    scopus 로고
    • Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis
    • Caplice NM, Panetta C, Peterson TE et al: Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis. Blood 2001; 98: 2980-2987.
    • (2001) Blood , vol.98 , pp. 2980-2987
    • Caplice, N.M.1    Panetta, C.2    Peterson, T.E.3
  • 31
    • 11144233997 scopus 로고    scopus 로고
    • Oxysterols and Rxysterol binding proteins: Role in lipid metabolism and atherosclerosis
    • Olkkonen VM, Lehto M: Oxysterols and Rxysterol binding proteins: role in lipid metabolism and atherosclerosis. Ann Med 2004; 36: 562-572.
    • (2004) Ann Med , vol.36 , pp. 562-572
    • Olkkonen, V.M.1    Lehto, M.2
  • 32
    • 33751072935 scopus 로고    scopus 로고
    • Bioenergetics and the formation of mitochondrial reactive oxygen species
    • Adam-Vizi V, Chinopoulos C: Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol Sci 2006; 27: 639-645.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 639-645
    • Adam-Vizi, V.1    Chinopoulos, C.2
  • 33
    • 33947723940 scopus 로고    scopus 로고
    • Characterization of superoxide production from aldehyde oxidase: An important source of oxidants in biological tissues
    • Kundu TK, Hille R, Velayutham M, Zweier JL: Characterization of superoxide production from aldehyde oxidase: An important source of oxidants in biological tissues. Arch Biochem Biophys 2007; 460 113-121.
    • (2007) Arch Biochem Biophys , vol.460 , pp. 113-121
    • Kundu, T.K.1    Hille, R.2    Velayutham, M.3    Zweier, J.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.