메뉴 건너뛰기




Volumn 98, Issue 10, 1996, Pages 2414-2424

Kringle-containing fragments of apolipoprotein(a) circulate in human plasma and are excreted into the urine

Author keywords

heparin; kidney; lipoprotein(a); monkey; mouse

Indexed keywords

APOLIPOPROTEIN A1; LIPOPROTEIN A;

EID: 0029832040     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119055     Document Type: Article
Times cited : (88)

References (41)
  • 1
    • 0002286713 scopus 로고
    • Lipoprotein(a)
    • C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw Hill Inc., New York
    • Utermann, G. 1995. Lipoprotein(a). In The Metabolic Basis of Inherited Disease. C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw Hill Inc., New York. 1887-1912.
    • (1995) The Metabolic Basis of Inherited Disease , pp. 1887-1912
    • Utermann, G.1
  • 2
    • 0025820340 scopus 로고
    • Lipoprotein(a) and atherosclerosis
    • Scanu, A.M. 1991. Lipoprotein(a) and atherosclerosis. Ann. Intern. Med. 115:209-218.
    • (1991) Ann. Intern. Med. , vol.115 , pp. 209-218
    • Scanu, A.M.1
  • 3
    • 0027992362 scopus 로고
    • Vascular interactions of lipoprotein(a)
    • Liu, A.C., and R.M. Lawn. 1994. Vascular interactions of lipoprotein(a). Curr. Opin. Lipidol. 5:269-273.
    • (1994) Curr. Opin. Lipidol. , vol.5 , pp. 269-273
    • Liu, A.C.1    Lawn, R.M.2
  • 4
    • 0028915169 scopus 로고
    • Different evolutionary histories of kringle and protease domains in serine proteases: A typical example of domain evolution
    • Ikeo, K., K. Takahashi, and T. Gojohori. 1995. Different evolutionary histories of kringle and protease domains in serine proteases: a typical example of domain evolution. J. Mol. Evol. 40:331-336.
    • (1995) J. Mol. Evol. , vol.40 , pp. 331-336
    • Ikeo, K.1    Takahashi, K.2    Gojohori, T.3
  • 5
    • 0027204250 scopus 로고
    • Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3
    • Yoshimura, T., N. Yuhki, M. Wang, A. Skee, and E.J. Leonard. 1993. Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3. J. Biol. Chem. 268:15461-15468.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15461-15468
    • Yoshimura, T.1    Yuhki, N.2    Wang, M.3    Skee, A.4    Leonard, E.J.5
  • 6
    • 0002258131 scopus 로고
    • Structural properties of apo(a): A major apoprotein of human lipoprotein(a)
    • A. Scanu, editor. Academic Press, Inc., San Diego, CA
    • Morrisett, J., J. Gaubatz, R. Knapp, and J.G. Guevara. 1990. Structural properties of apo(a): a major apoprotein of human lipoprotein(a). In Lipoprotein(a). A. Scanu, editor. Academic Press, Inc., San Diego, CA. 53-74.
    • (1990) Lipoprotein(a) , pp. 53-74
    • Morrisett, J.1    Gaubatz, J.2    Knapp, R.3    Guevara, J.G.4
  • 7
    • 0027179248 scopus 로고
    • Molecular definition of the extreme size polymorphism in apolipoprotein(a)
    • Lackner, C., J.C. Cohen, and H.H. Hobbs. 1993. Molecular definition of the extreme size polymorphism in apolipoprotein(a). Hum. Mol. Genet. 2:933-940.
    • (1993) Hum. Mol. Genet. , vol.2 , pp. 933-940
    • Lackner, C.1    Cohen, J.C.2    Hobbs, H.H.3
  • 10
    • 0028123481 scopus 로고
    • Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor
    • Mizuno, K., H. Inoue, M. Hagiya, S. Shimizu, T. Nose, Y. Shimohigashi, and T. Nakamura. 1994. Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor. J. Biol. Chem. 269:1131-1136.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1131-1136
    • Mizuno, K.1    Inoue, H.2    Hagiya, M.3    Shimizu, S.4    Nose, T.5    Shimohigashi, Y.6    Nakamura, T.7
  • 13
    • 0030027648 scopus 로고    scopus 로고
    • Apo(a) kringle 4-containing fragments in human urine. Relationship to plasma levels of lipoprotein(a)
    • Mooser, V., M.C. Seabra, M. Abedin, K.T. Landschulz, S. Marcovina, and H.H. Hobbs. 1996. Apo(a) kringle 4-containing fragments in human urine. Relationship to plasma levels of lipoprotein(a). J. Clin. Invest. 97:858-864.
    • (1996) J. Clin. Invest. , vol.97 , pp. 858-864
    • Mooser, V.1    Seabra, M.C.2    Abedin, M.3    Landschulz, K.T.4    Marcovina, S.5    Hobbs, H.H.6
  • 14
    • 0028985381 scopus 로고
    • Effect of the number of apolipoprotein(a) kringle 4 domains on immunochemical measurements of lipoprotein(a)
    • Marcovina, S.M., J.J. Albers, B. Gabel, M.L. Koschinsky, and V.P. Gaur. 1995. Effect of the number of apolipoprotein(a) kringle 4 domains on immunochemical measurements of lipoprotein(a). Clin. Chem. 41:246-255.
    • (1995) Clin. Chem. , vol.41 , pp. 246-255
    • Marcovina, S.M.1    Albers, J.J.2    Gabel, B.3    Koschinsky, M.L.4    Gaur, V.P.5
  • 15
    • 0026498273 scopus 로고
    • Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a)
    • Chiesa, G., H.H. Hobbs, M.L. Koschinsky, R.M. Lawn, S.D. Maika, and R.E. Hammer. 1992. Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a). J. Biol. Chem. 267:24369-24374.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24369-24374
    • Chiesa, G.1    Hobbs, H.H.2    Koschinsky, M.L.3    Lawn, R.M.4    Maika, S.D.5    Hammer, R.E.6
  • 17
    • 0024506133 scopus 로고
    • Hereditary and dietary effects on apolipoprotein(a) isoforms and Lp(a) in baboons
    • Rainwater, D.L., G.S. Manis, and J.L. VandeBerg. 1989. Hereditary and dietary effects on apolipoprotein(a) isoforms and Lp(a) in baboons. J. Lipid Res. 30:549-558.
    • (1989) J. Lipid Res. , vol.30 , pp. 549-558
    • Rainwater, D.L.1    Manis, G.S.2    Vandeberg, J.L.3
  • 18
    • 0024616032 scopus 로고
    • Analysis of plasma protein and lipoprotein synthesis in long-term primary cultures of baboon hepatocytes maintained in serum-free medium
    • Lanford, R.E., K.D. Carey, L.E. Estlack, G.C. Smith, and R.V. Hay. 1989. Analysis of plasma protein and lipoprotein synthesis in long-term primary cultures of baboon hepatocytes maintained in serum-free medium. In Vitro Cell. Dev. Biol. 25:174-182.
    • (1989) In Vitro Cell. Dev. Biol. , vol.25 , pp. 174-182
    • Lanford, R.E.1    Carey, K.D.2    Estlack, L.E.3    Smith, G.C.4    Hay, R.V.5
  • 19
    • 0028200883 scopus 로고
    • Comparative analysis of the apo(a) gene, apo(a) glycoprotein and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus
    • Gaw, A., E. Boerwinkle, J.C. Cohen, and H.H. Hobbs. 1994. Comparative analysis of the apo(a) gene, apo(a) glycoprotein and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus. J. Clin. Invest. 93:2526-2534.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2526-2534
    • Gaw, A.1    Boerwinkle, E.2    Cohen, J.C.3    Hobbs, H.H.4
  • 20
    • 0025812777 scopus 로고
    • Apolipoprotein(a): Expression and characterization of a recombinant form of the protein in mammalian cells
    • Koschinsky, M.L., J.E. Tomlinson, T.F. Zioncheck, K. Schwartz, D.L. Eaton, and R.M. Lawn. 1991. Apolipoprotein(a): expression and characterization of a recombinant form of the protein in mammalian cells. Biochemistry. 30: 5044-5051.
    • (1991) Biochemistry , vol.30 , pp. 5044-5051
    • Koschinsky, M.L.1    Tomlinson, J.E.2    Zioncheck, T.F.3    Schwartz, K.4    Eaton, D.L.5    Lawn, R.M.6
  • 21
    • 0023196646 scopus 로고
    • Characterization of an abnormal species of apolipoprotein B, apolipoprotein B-37, associated with familial hypobetalipoproteinemia
    • Young, S.G., S.J. Bertics, L.K. Curtiss, and J.L. Witztum. 1987. Characterization of an abnormal species of apolipoprotein B, apolipoprotein B-37, associated with familial hypobetalipoproteinemia. J. Clin. Invest. 79:1831-1841.
    • (1987) J. Clin. Invest. , vol.79 , pp. 1831-1841
    • Young, S.G.1    Bertics, S.J.2    Curtiss, L.K.3    Witztum, J.L.4
  • 23
    • 0025861618 scopus 로고
    • Plasma lipoprotein(a) concentration is controlled by apolipoprotein(a) (Apo(a)) protein size and the abundance of hepatic apo(a) mRNA in a cynomolgus monkey model
    • Azrolan, N., D. Gavish, and J.L. Breslow. 1991. Plasma lipoprotein(a) concentration is controlled by apolipoprotein(a) (Apo(a)) protein size and the abundance of hepatic apo(a) mRNA in a cynomolgus monkey model. J. Biol. Chem. 266:13866-13872.
    • (1991) J. Biol. Chem. , vol.266 , pp. 13866-13872
    • Azrolan, N.1    Gavish, D.2    Breslow, J.L.3
  • 24
    • 0024529337 scopus 로고
    • Changes in genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis
    • Kraft, H.G., H.J. Menzel, F. Hoppichler, W. Vogel, and G. Utermann. 1989. Changes in genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis. J. Clin. Invest. 83:137-142.
    • (1989) J. Clin. Invest. , vol.83 , pp. 137-142
    • Kraft, H.G.1    Menzel, H.J.2    Hoppichler, F.3    Vogel, W.4    Utermann, G.5
  • 25
    • 0029128048 scopus 로고
    • Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein(a)
    • Callow, M.J., J. Verstuyft, R. Tangirala, W. Palinski, and E.M. Rubin. 1995. Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein(a). J. Clin. Invest. 96:1639-1646.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1639-1646
    • Callow, M.J.1    Verstuyft, J.2    Tangirala, R.3    Palinski, W.4    Rubin, E.M.5
  • 26
    • 0027219204 scopus 로고
    • Alternative readings of the genetic code
    • Farabaugh, P.J. 1993. Alternative readings of the genetic code. Cell. 74: 591-596.
    • (1993) Cell , vol.74 , pp. 591-596
    • Farabaugh, P.J.1
  • 27
    • 0025060734 scopus 로고
    • Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA
    • Koschinsky, M.L., U. Beisiegel, D. Henne-Bruns, D.L. Eaton, and R.M. Lawn. 1990. Apolipoprotein(a) size heterogeneity is related to variable number of repeat sequences in its mRNA. Biochemistry. 29:640-644.
    • (1990) Biochemistry , vol.29 , pp. 640-644
    • Koschinsky, M.L.1    Beisiegel, U.2    Henne-Bruns, D.3    Eaton, D.L.4    Lawn, R.M.5
  • 28
    • 0024560045 scopus 로고
    • Apolipoprotein(a) (apo(a)) glycoprotein isoforms result from size differences in apo(a) mRNA in baboons
    • Hixon, J.E., M.L. Britten, G.S. Manis, and D.L. Rainwater. 1989. Apolipoprotein(a) (apo(a)) glycoprotein isoforms result from size differences in apo(a) mRNA in baboons. J. Clin. Invest. 264:6013-6016.
    • (1989) J. Clin. Invest. , vol.264 , pp. 6013-6016
    • Hixon, J.E.1    Britten, M.L.2    Manis, G.S.3    Rainwater, D.L.4
  • 29
    • 0027477975 scopus 로고
    • Intracellular maturation of apolipoprotein(a) and assembly of lipoprotein(a) in primary baboon hepatocytes
    • White, A.L., D.L. Rainwater, and R.E. Lanford. 1993. Intracellular maturation of apolipoprotein(a) and assembly of lipoprotein(a) in primary baboon hepatocytes. J. Lipid Res. 34:509-517.
    • (1993) J. Lipid Res. , vol.34 , pp. 509-517
    • White, A.L.1    Rainwater, D.L.2    Lanford, R.E.3
  • 30
    • 0030056374 scopus 로고    scopus 로고
    • Proteolytic cleavage and activation of pro-macrophage-stimulating protein by resident peritoneal macrophage membrane proteases
    • Wang, M., A. Skeel, and E.J. Leonard. 1996. Proteolytic cleavage and activation of pro-macrophage-stimulating protein by resident peritoneal macrophage membrane proteases. J. Clin. Invest. 97:720-727.
    • (1996) J. Clin. Invest. , vol.97 , pp. 720-727
    • Wang, M.1    Skeel, A.2    Leonard, E.J.3
  • 31
    • 0027220885 scopus 로고
    • Identification of the cysteine residue in apolipoprotein(a) that mediates extracellular coupling with apolipoprotein B-100
    • Koschinsky, M.L., G.P. Côté, B. Gabel, and Y.Y. Van der Hoek. 1993. Identification of the cysteine residue in apolipoprotein(a) that mediates extracellular coupling with apolipoprotein B-100. J. Biol. Chem. 268:19819-19825.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19819-19825
    • Koschinsky, M.L.1    Côté, G.P.2    Gabel, B.3    Van Der Hoek, Y.Y.4
  • 32
    • 0027333433 scopus 로고
    • Cys4057 of apolipoprolein(a) is essential for lipoprotein(a) assembly
    • Brunner, C., H.G. Kraft, G. Utermann, and H.J. Muller. 1993. Cys4057 of apolipoprolein(a) is essential for lipoprotein(a) assembly. Proc. Natl. Acad. Sci. USA. 90:11643-11647.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11643-11647
    • Brunner, C.1    Kraft, H.G.2    Utermann, G.3    Muller, H.J.4
  • 33
    • 0028921349 scopus 로고
    • Identification of two functionally distinct lysine-binding sites in kringle 37 and in kringle 32-36 of human apolipoprotein(a)
    • Ernst, A., M. Helmhold, C. Brunner, A. Pethö-Schramm, V.W. Armstrong, and H. Müller. 1995. Identification of two functionally distinct lysine-binding sites in kringle 37 and in kringle 32-36 of human apolipoprotein(a). J. Biol. Chem. 270:6227-6234.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6227-6234
    • Ernst, A.1    Helmhold, M.2    Brunner, C.3    Pethö-Schramm, A.4    Armstrong, V.W.5    Müller, H.6
  • 35
    • 0027216206 scopus 로고
    • Partial characterization of lipoproteins containing apo(a) in human atherosclerotic lesions
    • Hoff, H.F., J. O'Neil, and A. Yashiro. 1993. Partial characterization of lipoproteins containing apo(a) in human atherosclerotic lesions. J. Lipid Res. 34:789-798.
    • (1993) J. Lipid Res. , vol.34 , pp. 789-798
    • Hoff, H.F.1    O'Neil, J.2    Yashiro, A.3
  • 36
    • 0021908034 scopus 로고
    • Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B
    • Guyton, J.R., G.H. Dahlen, W. Patsch, J.A. Kautz, and A. Gotto, Jr. 1985. Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B. J. Clin. Invest. 5:265-272.
    • (1985) J. Clin. Invest. , vol.5 , pp. 265-272
    • Guyton, J.R.1    Dahlen, G.H.2    Patsch, W.3    Kautz, J.A.4    Gotto Jr., A.5
  • 37
    • 0026560389 scopus 로고
    • Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population. Evidence for the role of the apo(a) gene in coronary heart disease
    • Sandholzer, C., E. Boerwinkle, N. Saha, M.C. Tong, and G. Utermann. 1992. Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population. Evidence for the role of the apo(a) gene in coronary heart disease. J Clin. Invest. 89:1040-1046.
    • (1992) J Clin. Invest. , vol.89 , pp. 1040-1046
    • Sandholzer, C.1    Boerwinkle, E.2    Saha, N.3    Tong, M.C.4    Utermann, G.5
  • 40
    • 0027475415 scopus 로고
    • Elevated plasma concentrations of lipoprotein(a) in patients with end-stage renal disease are not related to the size polymorphism of apolipoprotein(a)
    • Dieplinger, H., C. Lackner, F. Kronenberg, C. Sandholzer, K. Lhotta, F. Hoppichler, H. Graf, and P. Konig. 1993. Elevated plasma concentrations of lipoprotein(a) in patients with end-stage renal disease are not related to the size polymorphism of apolipoprotein(a). J. Clin. Invest. 91:397-401.
    • (1993) J. Clin. Invest. , vol.91 , pp. 397-401
    • Dieplinger, H.1    Lackner, C.2    Kronenberg, F.3    Sandholzer, C.4    Lhotta, K.5    Hoppichler, F.6    Graf, H.7    Konig, P.8
  • 41
    • 0027368426 scopus 로고
    • Apolipoprotein(a) phenotypes and serum lipoprotein(a) levels in maintenance hemodialysis patients with/without diabetes mellitus
    • Hirata, K., S. Kikuchi, K. Saku, S. Jimi, B. Zhang, S. Naito, H. Hamaguchi, and K. Arakawa. 1993. Apolipoprotein(a) phenotypes and serum lipoprotein(a) levels in maintenance hemodialysis patients with/without diabetes mellitus. Kidney Int. 44: 1062-1070.
    • (1993) Kidney Int. , vol.44 , pp. 1062-1070
    • Hirata, K.1    Kikuchi, S.2    Saku, K.3    Jimi, S.4    Zhang, B.5    Naito, S.6    Hamaguchi, H.7    Arakawa, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.