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Volumn 7, Issue 2, 1999, Pages 169-178

Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians

Author keywords

Africans; Apolipoprotein(a); Caucasians; Family analysis; Heritability; Lipoprotein(a); Quantitative genetic trait; Sibpair analysis

Indexed keywords

APOLIPOPROTEIN A; LIPOPROTEIN A;

EID: 0033058188     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200290     Document Type: Article
Times cited : (59)

References (52)
  • 1
    • 0002286713 scopus 로고
    • Lipoprotein(a)
    • Scriver CR, Beaudet AL, Sly WS, Stanbury JB, Wyngaarden JB, Fredrickson DS (eds). McGraw-Hill: New York
    • Utermann G: Lipoprotein(a). In: Scriver CR, Beaudet AL, Sly WS, Stanbury JB, Wyngaarden JB, Fredrickson DS (eds). The Metabolic and Molecular Bases of Inherited Disease. McGraw-Hill: New York, 1995, II, pp 1887-1912.
    • (1995) The Metabolic and Molecular Bases of Inherited Disease , vol.2 , pp. 1887-1912
    • Utermann, G.1
  • 2
    • 0028215765 scopus 로고
    • Molecular genetics of lipoprotein (a): New pieces to the puzzle
    • Gaw A, Hobbs HH: Molecular genetics of lipoprotein (a): new pieces to the puzzle. Curr Opin Lipidol 1994; 5: 149-155.
    • (1994) Curr Opin Lipidol , vol.5 , pp. 149-155
    • Gaw, A.1    Hobbs, H.H.2
  • 3
    • 0026560389 scopus 로고
    • Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population - Evidence for the role of the apo(a) gene in coronary heart disease
    • Sandholzer C, Boerwinkle E, Saha N, Tong MC, Utermann G: Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population - evidence for the role of the apo(a) gene in coronary heart disease. J Clin Invest 1992; 89: 1040-1046.
    • (1992) J Clin Invest , vol.89 , pp. 1040-1046
    • Sandholzer, C.1    Boerwinkle, E.2    Saha, N.3    Tong, M.C.4    Utermann, G.5
  • 4
    • 0030014389 scopus 로고    scopus 로고
    • Apolipoprotein(a) kringle IV repeat number predicts risk for coronary heart disease
    • Kraft HG, Lingenhel A, Köchl S et al: Apolipoprotein(a) kringle IV repeat number predicts risk for coronary heart disease. Arterioscler Thromb Vasc Biol 1996; 16: 713-719.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 713-719
    • Kraft, H.G.1    Lingenhel, A.2    Köchl, S.3
  • 5
    • 0029740582 scopus 로고    scopus 로고
    • Elevated plasma lipoprotein(a) and coronary heart disease in men aged 55 years and younger - A prospective study
    • Bostom AG, Cupples LA, Jenner JL et al: Elevated plasma lipoprotein(a) and coronary heart disease in men aged 55 years and younger - a prospective study. JAMA 1996; 276: 544-548.
    • (1996) JAMA , vol.276 , pp. 544-548
    • Bostom, A.G.1    Cupples, L.A.2    Jenner, J.L.3
  • 6
    • 85047690177 scopus 로고
    • Lipoprotein(a) - A genetic risk factor for premature coronary heart disease
    • Scanu AM: Lipoprotein(a) - a genetic risk factor for premature coronary heart disease. JAMA 1992; 267: 3326-3329.
    • (1992) JAMA , vol.267 , pp. 3326-3329
    • Scanu, A.M.1
  • 7
    • 0026452123 scopus 로고
    • Plasma lipoprotein(a) protein concentration and coronary artery disease in black patients compared with white patients
    • Sorrentino MJ, Vielhauer C, Eisenbart JD, Fless GM, Scanu AM, Feldman T: Plasma lipoprotein(a) protein concentration and coronary artery disease in black patients compared with white patients. Am J Med 1992; 93: 658-662.
    • (1992) Am J Med , vol.93 , pp. 658-662
    • Sorrentino, M.J.1    Vielhauer, C.2    Eisenbart, J.D.3    Fless, G.M.4    Scanu, A.M.5    Feldman, T.6
  • 8
    • 0027360450 scopus 로고
    • Serum lipoprotein(A) levels in elderly black and white men in the Charleston Heart Study
    • Knapp RG, Schreiner PJ, Sutherland SE et al: Serum lipoprotein(A) levels in elderly black and white men in the Charleston Heart Study. Clin Genet 1993; 44: 225-231.
    • (1993) Clin Genet , vol.44 , pp. 225-231
    • Knapp, R.G.1    Schreiner, P.J.2    Sutherland, S.E.3
  • 9
    • 0023636242 scopus 로고
    • cDNA sequence of human apolipoprotein (a) is homologous to plasminogen
    • McLean JW, Tomlinson JE, Kuang W et al: cDNA sequence of human apolipoprotein (a) is homologous to plasminogen. Nature 1987; 300: 132-137.
    • (1987) Nature , vol.300 , pp. 132-137
    • McLean, J.W.1    Tomlinson, J.E.2    Kuang, W.3
  • 11
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH: Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest 1992; 90: 52-60.
    • (1992) J Clin Invest , vol.90 , pp. 52-60
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3    Lackner, C.4    Chiesa, G.5    Hobbs, H.H.6
  • 12
    • 0026526357 scopus 로고
    • The apolipoprotein(a) gene - A transcribed hyper-variable locus controlling plasma lipoprotein(a) concentration
    • Kraft HG, Köchl S, Menzel HJ, Sandholzer C, Utermann G: The apolipoprotein(a) gene - a transcribed hyper-variable locus controlling plasma lipoprotein(a) concentration. Hum Genet 1992; 90: 220-230.
    • (1992) Hum Genet , vol.90 , pp. 220-230
    • Kraft, H.G.1    Köchl, S.2    Menzel, H.J.3    Sandholzer, C.4    Utermann, G.5
  • 13
    • 0023689329 scopus 로고
    • The apolipoprotein (a) gene resides on human chromosome 6q26-27 in close proximity to the homologous gene for plasminogen
    • Frank SL, Klisak I, Sparkes RS et al: The apolipoprotein (a) gene resides on human chromosome 6q26-27 in close proximity to the homologous gene for plasminogen. Hum Genet 1988; 79: 352-356.
    • (1988) Hum Genet , vol.79 , pp. 352-356
    • Frank, S.L.1    Klisak, I.2    Sparkes, R.S.3
  • 14
    • 0024589078 scopus 로고
    • The gene for the Lp (a) specific glycoprotein is closely linked to the gene for plasminogen on chromosome 6
    • Lindahl G, Gersdorf E, Menzel HJ et al: The gene for the Lp (a) specific glycoprotein is closely linked to the gene for plasminogen on chromosome 6. Hum Genet 1989; 81: 149-152.
    • (1989) Hum Genet , vol.81 , pp. 149-152
    • Lindahl, G.1    Gersdorf, E.2    Menzel, H.J.3
  • 15
    • 0028854118 scopus 로고
    • Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus
    • Demeester CA, Bu X, Gray RJ, Lusis AJ, Rotter JI: Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus. Am J Hum Genet 1995; 56: 287-293.
    • (1995) Am J Hum Genet , vol.56 , pp. 287-293
    • Demeester, C.A.1    Bu, X.2    Gray, R.J.3    Lusis, A.J.4    Rotter, J.I.5
  • 16
    • 0029916008 scopus 로고    scopus 로고
    • Frequency distributions of apolipoprotein(a) kringle IV repeat alleles and their effects on lipoprotein(a) levels in Caucasian, Asian, and African populations: The distribution of null alleles is non-random
    • Kraft HG, Lingenhel A, Pang RWC et al: Frequency distributions of apolipoprotein(a) kringle IV repeat alleles and their effects on lipoprotein(a) levels in Caucasian, Asian, and African populations: The distribution of null alleles is non-random. Eur J Hum Genet 1996; 4: 74-87.
    • (1996) Eur J Hum Genet , vol.4 , pp. 74-87
    • Kraft, H.G.1    Lingenhel, A.2    Pang, R.W.C.3
  • 17
    • 0028200883 scopus 로고
    • Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups -evidence for no common 'null' allele at the apo(a) locus
    • Gaw A, Boerwinkle E, Cohen JC, Hobbs HH: Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups -evidence for no common 'null' allele at the apo(a) locus. J Clin Invest 1994; 93: 2526-2534.
    • (1994) J Clin Invest , vol.93 , pp. 2526-2534
    • Gaw, A.1    Boerwinkle, E.2    Cohen, J.C.3    Hobbs, H.H.4
  • 18
    • 0025905304 scopus 로고
    • Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups
    • Sandholzer C, Hallman DM, Saha N et al: Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups. Hum Genet 1991; 86: 607-614.
    • (1991) Hum Genet , vol.86 , pp. 607-614
    • Sandholzer, C.1    Hallman, D.M.2    Saha, N.3
  • 19
    • 0029145665 scopus 로고
    • A pentanucleotide repeat polymorphism in the 5′ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians
    • Trommsdorff M, Köchl S, Lingenhel A et al: A pentanucleotide repeat polymorphism in the 5′ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians. J Clin Invest 1995; 96: 150-157.
    • (1995) J Clin Invest , vol.96 , pp. 150-157
    • Trommsdorff, M.1    Köchl, S.2    Lingenhel, A.3
  • 20
    • 0027214793 scopus 로고
    • Lipoprotein[a] concentrations and apolipoprotein[a] phenotypes in Caucasians and African Americans - The CARDIA Study
    • Marcovina SM, Albers JJ, Jacobs DR et al: Lipoprotein[a] concentrations and apolipoprotein[a] phenotypes in Caucasians and African Americans - The CARDIA Study. Arterioscler Thromb 1993; 13: 1037-1045.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1037-1045
    • Marcovina, S.M.1    Albers, J.J.2    Jacobs, D.R.3
  • 21
    • 0030799057 scopus 로고    scopus 로고
    • The apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans
    • Mooser V, Scheer D, Marcovina SM et al: The apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans. Am J Hum Genet 1997; 61: 402-417.
    • (1997) Am J Hum Genet , vol.61 , pp. 402-417
    • Mooser, V.1    Scheer, D.2    Marcovina, S.M.3
  • 22
    • 0031975642 scopus 로고    scopus 로고
    • Significant impact of the + 93 C/T polymorphism in the apolipoprotein(a) gene on Lp(a) concentrations in Africans but not in Caucasians: Confounding effect of linkage disequilibrium
    • Kraft HG, Windegger M, Menzel HJ, Utermann G: Significant impact of the + 93 C/T polymorphism in the apolipoprotein(a) gene on Lp(a) concentrations in Africans but not in Caucasians: confounding effect of linkage disequilibrium. Hum Mol Genet 1998; 7: 257-264.
    • (1998) Hum Mol Genet , vol.7 , pp. 257-264
    • Kraft, H.G.1    Windegger, M.2    Menzel, H.J.3    Utermann, G.4
  • 23
    • 0028847829 scopus 로고
    • High frequency of the apo epsilon 4 allele in Khoi San from South Africa
    • Sandholzer C, Delport R, Vermaak H, Utermann G: High frequency of the apo epsilon 4 allele in Khoi San from South Africa. Hum Genet 1995; 95: 46-48.
    • (1995) Hum Genet , vol.95 , pp. 46-48
    • Sandholzer, C.1    Delport, R.2    Vermaak, H.3    Utermann, G.4
  • 24
    • 0028174206 scopus 로고
    • Effect of sample storage on the measurement of lipoprotein(a), apolipoproteins B and A-IV, total and high density lipoprotein cholesterol and triglycerides
    • Kronenberg F, Lobentanz E, König P, Utermann G, Dieplinger H: Effect of sample storage on the measurement of lipoprotein(a), apolipoproteins B and A-IV, total and high density lipoprotein cholesterol and triglycerides. J Lipid Res 1994; 35: 1318-1328.
    • (1994) J Lipid Res , vol.35 , pp. 1318-1328
    • Kronenberg, F.1    Lobentanz, E.2    König, P.3    Utermann, G.4    Dieplinger, H.5
  • 25
    • 0028901444 scopus 로고
    • Sequence polymorphism in kringle IV 37 in linkage disequilibrium with the apolipoprotein (a) size polymorphism
    • Kraft HG, Haibach C, Lingenhel A et al: Sequence polymorphism in kringle IV 37 in linkage disequilibrium with the apolipoprotein (a) size polymorphism. Hum Genet 1995; 95: 275-282.
    • (1995) Hum Genet , vol.95 , pp. 275-282
    • Kraft, H.G.1    Haibach, C.2    Lingenhel, A.3
  • 28
    • 0028058128 scopus 로고
    • Robust variance-components approach for assessing genetic linkage in pedigrees
    • Amos CI: Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet 1994; 54: 535-543.
    • (1994) Am J Hum Genet , vol.54 , pp. 535-543
    • Amos, C.I.1
  • 29
    • 0029875522 scopus 로고    scopus 로고
    • Assessing genetic linkage and association with robust components of variance approaches
    • Amos CI, Zhu DK, Boerwinkle E: Assessing genetic linkage and association with robust components of variance approaches. Am J Hum Genet 1996; 60: 143-160.
    • (1996) Am J Hum Genet , vol.60 , pp. 143-160
    • Amos, C.I.1    Zhu, D.K.2    Boerwinkle, E.3
  • 30
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC: The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 1972; 2: 3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 31
    • 0003796769 scopus 로고
    • Release 2.2. Computer program package available from the Department of Epidemiology and Biostatistics, Case Western Reserve University: Cleveland
    • SAGE Statistical Analysis for Genetic Epidemiology. 1994. Release 2.2. Computer program package available from the Department of Epidemiology and Biostatistics, Case Western Reserve University: Cleveland.
    • (1994) SAGE Statistical Analysis for Genetic Epidemiology
  • 32
    • 0030817624 scopus 로고    scopus 로고
    • Fieller's theorem, Scheffe simultaneous confidence intervals and ratios of parameters of linear and nonlinear mixed-effects models
    • Young DA, Zerbe GO, Hay WWJ: Fieller's theorem, Scheffe simultaneous confidence intervals and ratios of parameters of linear and nonlinear mixed-effects models. Biometrics 1997; 53: 838-847.
    • (1997) Biometrics , vol.53 , pp. 838-847
    • Young, D.A.1    Zerbe, G.O.2    Hay, W.W.J.3
  • 33
    • 0028945089 scopus 로고
    • C/T polymorphism in the 5′ untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation
    • Zysow BR, Lindahl GE, Wade DP, Knight BL, Lawn RM: C/T polymorphism in the 5′ untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation. Arterioscler Thromb Vasc Biol 1995; 15: 58-64.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 58-64
    • Zysow, B.R.1    Lindahl, G.E.2    Wade, D.P.3    Knight, B.L.4    Lawn, R.M.5
  • 34
    • 0031046798 scopus 로고    scopus 로고
    • Influence of allelic variation on apolipoprotein(a) folding in the endoplasmic reticulum
    • White AL, Guerra B, Lanford RE: Influence of allelic variation on apolipoprotein(a) folding in the endoplasmic reticulum. J Biol Chem 1997; 272: 5048-5055.
    • (1997) J Biol Chem , vol.272 , pp. 5048-5055
    • White, A.L.1    Guerra, B.2    Lanford, R.E.3
  • 35
    • 0026347098 scopus 로고
    • Contribution of the apo(a) phenotype to plasma Lp(a) concentrations shows considerable ethnic variation
    • Helmhold M, Bigge J, Muche R et al: Contribution of the apo(a) phenotype to plasma Lp(a) concentrations shows considerable ethnic variation. J Lipid Res 1991; 32: 1919-1928.
    • (1991) J Lipid Res , vol.32 , pp. 1919-1928
    • Helmhold, M.1    Bigge, J.2    Muche, R.3
  • 37
    • 0021908034 scopus 로고
    • Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B
    • Guyton JR, Dahlen GH, Patsch W, Kautz JA, Gotto AMJ: Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B. Arteriosclerosis 1985; 5(3): 265-272.
    • (1985) Arteriosclerosis , vol.5 , Issue.3 , pp. 265-272
    • Guyton, J.R.1    Dahlen, G.H.2    Patsch, W.3    Kautz, J.A.4    Gotto, A.M.J.5
  • 39
    • 0025997058 scopus 로고
    • The NHLBI Twin Study: Heritability of apolipoprotein A-I, B and concordance for lipoprotein(a)
    • Lamon-Fava S, Jimenez D, Christian JC et al: The NHLBI Twin Study: heritability of apolipoprotein A-I, B and concordance for lipoprotein(a). Atherosclerosis 1991; 91: 97-106.
    • (1991) Atherosclerosis , vol.91 , pp. 97-106
    • Lamon-Fava, S.1    Jimenez, D.2    Christian, J.C.3
  • 40
    • 0030897464 scopus 로고    scopus 로고
    • Stearic acid, trans fatty acids, and dairy fat: Effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein(a), and lipid transfer proteins in healthy subjects
    • Aro A, Jauhiainen M, Partanen R, Salminen I, Mutanen M: Stearic acid, trans fatty acids, and dairy fat: effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein(a), and lipid transfer proteins in healthy subjects. Am J Clin Nutr 1997; 65: 1419-1426.
    • (1997) Am J Clin Nutr , vol.65 , pp. 1419-1426
    • Aro, A.1    Jauhiainen, M.2    Partanen, R.3    Salminen, I.4    Mutanen, M.5
  • 41
    • 0029873661 scopus 로고    scopus 로고
    • Dietary trans-fatty acids and serum lipoproteins in humans
    • Zock PL, Mensink RP: Dietary trans-fatty acids and serum lipoproteins in humans. Curr Opin Lipidol 1996; 7: 34-37.
    • (1996) Curr Opin Lipidol , vol.7 , pp. 34-37
    • Zock, P.L.1    Mensink, R.P.2
  • 42
    • 0029188466 scopus 로고
    • Cyclical variation of plasma lipids, apolipoproteins, and lipoprotein(a) during menstrual cycle of normal women
    • Tonolo G, Ciccarese M, Brizzi P et al: Cyclical variation of plasma lipids, apolipoproteins, and lipoprotein(a) during menstrual cycle of normal women. Am J Physiol 1995; 269: E1101-1105.
    • (1995) Am J Physiol , vol.269
    • Tonolo, G.1    Ciccarese, M.2    Brizzi, P.3
  • 43
    • 0028920057 scopus 로고
    • The apolipoprotein(a) gene is regulated by sex hormones and acute-phase inducers in YAC transgenic mice
    • Frazer KA, Narla G, Zhang JL, Rubin EM: The apolipoprotein(a) gene is regulated by sex hormones and acute-phase inducers in YAC transgenic mice. Nat Genet 1995; 9: 424-431.
    • (1995) Nat Genet , vol.9 , pp. 424-431
    • Frazer, K.A.1    Narla, G.2    Zhang, J.L.3    Rubin, E.M.4
  • 44
    • 0029759257 scopus 로고    scopus 로고
    • Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency
    • Hershkovitz E, Leiberman E, Limony Y, Shany S, Phillip M: Short-term growth hormone therapy increases serum lipoprotein (a) levels in normal short children without growth hormone deficiency. Horm Res 1996; 46: 38-40.
    • (1996) Horm Res , vol.46 , pp. 38-40
    • Hershkovitz, E.1    Leiberman, E.2    Limony, Y.3    Shany, S.4    Phillip, M.5
  • 46
    • 0025098439 scopus 로고
    • Abetalipoproteinemia with an ApoB-100-lipoprotein(a) glycoprotein complex in plasma - Indication for an assembly defect
    • Menzel HJ, Dieplinger H, Lackner K et al: Abetalipoproteinemia with an ApoB-100-lipoprotein(a) glycoprotein complex in plasma - indication for an assembly defect. J Biol Chem 1990; 265: 981-986.
    • (1990) J Biol Chem , vol.265 , pp. 981-986
    • Menzel, H.J.1    Dieplinger, H.2    Lackner, K.3
  • 47
    • 0028172990 scopus 로고
    • The role of lecithin: Cholesterol acyltransferase for lipoprotein (a) assembly. Structural integrity of low density lipoproteins is a prerequisite for Lp(a) formation in human plasma
    • Steyrer E, Durovic S, Frank S et al: The role of lecithin: cholesterol acyltransferase for lipoprotein (a) assembly. Structural integrity of low density lipoproteins is a prerequisite for Lp(a) formation in human plasma. J Clin Invest 1994; 94: 2330-2340.
    • (1994) J Clin Invest , vol.94 , pp. 2330-2340
    • Steyrer, E.1    Durovic, S.2    Frank, S.3
  • 48
    • 0030911569 scopus 로고    scopus 로고
    • Sib-pair analysis detects elevated Lp(a) levels and large variation of Lp(a) concentration in subjects with familiar defective ApoB
    • Van der Hoek YY, Lingenhel A, Kraft HG, Defesche JC, Kastelein JJP, Utermann G: Sib-pair analysis detects elevated Lp(a) levels and large variation of Lp(a) concentration in subjects with familiar defective ApoB. J Clin Invest 1997; 99: 2269-2273.
    • (1997) J Clin Invest , vol.99 , pp. 2269-2273
    • Van Der Hoek, Y.Y.1    Lingenhel, A.2    Kraft, H.G.3    Defesche, J.C.4    Kastelein, J.J.P.5    Utermann, G.6
  • 50
    • 0028025498 scopus 로고
    • Polymorphic admixture typing in human ethnic populations
    • Dean M, Stephens JC, Winkler C et al: Polymorphic admixture typing in human ethnic populations. Am J Hum Genet 1994; 55: 788-808.
    • (1994) Am J Hum Genet , vol.55 , pp. 788-808
    • Dean, M.1    Stephens, J.C.2    Winkler, C.3
  • 51
    • 0029731350 scopus 로고    scopus 로고
    • The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells
    • Brunner C, Lobentanz EM, Pethö-Schramm A et al: The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells. J Biol Chem 1996; 271: 32403-32410.
    • (1996) J Biol Chem , vol.271 , pp. 32403-32410
    • Brunner, C.1    Lobentanz, E.M.2    Pethö-Schramm, A.3
  • 52
    • 0030985016 scopus 로고    scopus 로고
    • Serum distribution of lipoprotein(a) in African Americans and Nigerians: Potential evidence for a genotype-environmental effect
    • Rotimi CN, Cooper RS, Marcovina SM, McGee D, Owoaje E, Ladipo M: Serum distribution of lipoprotein(a) in African Americans and Nigerians: potential evidence for a genotype-environmental effect. Genet Epidemiol 1997; 14: 157-168.
    • (1997) Genet Epidemiol , vol.14 , pp. 157-168
    • Rotimi, C.N.1    Cooper, R.S.2    Marcovina, S.M.3    McGee, D.4    Owoaje, E.5    Ladipo, M.6


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