메뉴 건너뛰기




Volumn 43, Issue 12, 2006, Pages 917-923

Three single-nucleotide polymorphisms in LPA account for most of the increase in lipoprotein(a) level elevation in African Americans compared with European Americans

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN; ISOPROTEIN; LIPOPROTEIN A;

EID: 33846168084     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.2006.042119     Document Type: Article
Times cited : (54)

References (38)
  • 1
    • 0037147189 scopus 로고    scopus 로고
    • Genetic structure of human populations
    • Rosenberg NA, Prtichard JK, Weber JL, et al. Genetic structure of human populations. Science 2002;298:2381-5.
    • (2002) Science , vol.298 , pp. 2381-2385
    • Rosenberg, N.A.1    Prtichard, J.K.2    Weber, J.L.3
  • 2
    • 0344091561 scopus 로고    scopus 로고
    • Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans
    • Carlson CS, Eberle MA, Rieder MJ, et al. Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nat Genet 2003;33:518-21.
    • (2003) Nat Genet , vol.33 , pp. 518-521
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3
  • 3
    • 0036381531 scopus 로고    scopus 로고
    • Risch N, Burchard E, Ziv E, et al. Categorization of humans in biomedical research: genes, race and disease. Genome Biol 2002;3:comment2007.
    • Risch N, Burchard E, Ziv E, et al. Categorization of humans in biomedical research: genes, race and disease. Genome Biol 2002;3:comment2007.
  • 4
    • 0036137030 scopus 로고    scopus 로고
    • A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/ control or family data: Application to HLA in type 1 diabetes
    • Cordell HJ, Clayton DG. A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/ control or family data: application to HLA in type 1 diabetes. Am J Hum Genet 2002;70:124-41.
    • (2002) Am J Hum Genet , vol.70 , pp. 124-141
    • Cordell, H.J.1    Clayton, D.G.2
  • 5
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich DE, Lander ES. On the allelic spectrum of human disease. Trends Genet 2001;17:502-10.
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 6
    • 0029916008 scopus 로고    scopus 로고
    • Frequency distributions of apolipoprotein(a) kringle IV repeat alleles and their effects on lipoprotein(a) levels in Caucasian, Asian, and African populations: The distribution of null alleles is non-random
    • Kraft HG, Lingenhel A, Pang RW, et al. Frequency distributions of apolipoprotein(a) kringle IV repeat alleles and their effects on lipoprotein(a) levels in Caucasian, Asian, and African populations: the distribution of null alleles is non-random. Eur J Hum Genet 1996;4:74-87.
    • (1996) Eur J Hum Genet , vol.4 , pp. 74-87
    • Kraft, H.G.1    Lingenhel, A.2    Pang, R.W.3
  • 7
    • 0030451016 scopus 로고    scopus 로고
    • Differences in Lp[a] concentrations and apo[a] polymorphs between black and white Americans
    • Marcovina SM, Albers JJ, Wijsman E, et al. Differences in Lp[a] concentrations and apo[a] polymorphs between black and white Americans. J Lipid Res 1996;37:2569-85.
    • (1996) J Lipid Res , vol.37 , pp. 2569-2585
    • Marcovina, S.M.1    Albers, J.J.2    Wijsman, E.3
  • 8
    • 0034609562 scopus 로고    scopus 로고
    • Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies
    • Danesh J, Collins R, Peto R. Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies. Circulation 2000;102:1082-5.
    • (2000) Circulation , vol.102 , pp. 1082-1085
    • Danesh, J.1    Collins, R.2    Peto, R.3
  • 9
    • 21444447949 scopus 로고    scopus 로고
    • Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease
    • Tsimikas S, Brilakis ES, Miller ER, et al. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med 2005;353:46-57.
    • (2005) N Engl J Med , vol.353 , pp. 46-57
    • Tsimikas, S.1    Brilakis, E.S.2    Miller, E.R.3
  • 10
    • 0026635611 scopus 로고
    • Lipoprotein(a). Link between structure and pathology
    • Scanu AM. Lipoprotein(a). Link between structure and pathology. Ann Epidemiol 1992;2:407-12.
    • (1992) Ann Epidemiol , vol.2 , pp. 407-412
    • Scanu, A.M.1
  • 11
    • 0025190963 scopus 로고
    • Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator
    • Edelberg JM, Gonzalez-Gronow M, Pizzo SV. Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator. Thromb Res 1990;57:155-62.
    • (1990) Thromb Res , vol.57 , pp. 155-162
    • Edelberg, J.M.1    Gonzalez-Gronow, M.2    Pizzo, S.V.3
  • 12
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, et al. Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest 1992;90:52-60.
    • (1992) J Clin Invest , vol.90 , pp. 52-60
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3
  • 13
    • 0030799057 scopus 로고    scopus 로고
    • The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans
    • Mooser V, Scheer D, Marcovina SM, et al. The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans. Am J Hum Genet 1997;61:402-17.
    • (1997) Am J Hum Genet , vol.61 , pp. 402-417
    • Mooser, V.1    Scheer, D.2    Marcovina, S.M.3
  • 14
    • 0032723934 scopus 로고    scopus 로고
    • The identification of polymorphisms in the coding region of the apolipoprotein (a) gene-association with earlier identified polymorphic sites and influence on the lipoprotein (a) concentration
    • Prins J, Leus FR, Bouma BN, et al. The identification of polymorphisms in the coding region of the apolipoprotein (a) gene-association with earlier identified polymorphic sites and influence on the lipoprotein (a) concentration. Thromb Haemost 1999;82:1709-17.
    • (1999) Thromb Haemost , vol.82 , pp. 1709-1717
    • Prins, J.1    Leus, F.R.2    Bouma, B.N.3
  • 15
    • 0029731350 scopus 로고    scopus 로고
    • The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells
    • Brunner C, Lobentanz E-M, Petho-Schramm A, et al. The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells. J Biol Chem 1996;271: 32403-10.
    • (1996) J Biol Chem , vol.271 , pp. 32403-32410
    • Brunner, C.1    Lobentanz, E.-M.2    Petho-Schramm, A.3
  • 16
    • 0028920022 scopus 로고
    • Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma
    • Mooser V, Mancini FP, Bopp S, et al. Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma. Hum Mol Genet 1995;4:173-81.
    • (1995) Hum Mol Genet , vol.4 , pp. 173-181
    • Mooser, V.1    Mancini, F.P.2    Bopp, S.3
  • 17
    • 0032837868 scopus 로고    scopus 로고
    • Molecular basis of congenital lp(a) deficiency: A frequent apo(a) 'null' mutation in caucasians
    • Ogorelkova M, Gruber A, Utermann G. Molecular basis of congenital lp(a) deficiency: a frequent apo(a) 'null' mutation in caucasians. Hum Mol Genet 1999;8:2087-96.
    • (1999) Hum Mol Genet , vol.8 , pp. 2087-2096
    • Ogorelkova, M.1    Gruber, A.2    Utermann, G.3
  • 18
    • 0035311403 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians
    • Ogorelkova M, Kraft HG, Ehnholm C, et al. Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians. Hum Mol Genet 2001;10:815-24.
    • (2001) Hum Mol Genet , vol.10 , pp. 815-824
    • Ogorelkova, M.1    Kraft, H.G.2    Ehnholm, C.3
  • 19
    • 0030808036 scopus 로고    scopus 로고
    • Polymorphisms in the apolipoprotein(a) gene and their relationship to allele size and plasma lipoprotein(a) concentration
    • Puckey LH, Lawn RM, Knight BL. Polymorphisms in the apolipoprotein(a) gene and their relationship to allele size and plasma lipoprotein(a) concentration. Hum Mol Genet 1997;6:1099-107.
    • (1997) Hum Mol Genet , vol.6 , pp. 1099-1107
    • Puckey, L.H.1    Lawn, R.M.2    Knight, B.L.3
  • 20
    • 0029145665 scopus 로고
    • A pentanucleotide repeat polymorphism in the 5′ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians
    • Trommsdorff M, Kochl S, Lingenhel A, et al. A pentanucleotide repeat polymorphism in the 5′ control region of the apolipoprotein(a) gene is associated with lipoprotein(a) plasma concentrations in Caucasians. J Clin Invest 1995;96:150-7.
    • (1995) J Clin Invest , vol.96 , pp. 150-157
    • Trommsdorff, M.1    Kochl, S.2    Lingenhel, A.3
  • 21
    • 0031975642 scopus 로고    scopus 로고
    • Significant impact of the +93 C/T polymorphism in the apolipoprotein(a) gene on Lp(a) concentrations in Africans but not in Caucasians: Confounding effect of linkage disequilibrium
    • Kraft HG, Windegger M, Menzel HJ, et al. Significant impact of the +93 C/T polymorphism in the apolipoprotein(a) gene on Lp(a) concentrations in Africans but not in Caucasians: confounding effect of linkage disequilibrium. Hum Mol Genet 1998;7:257-64.
    • (1998) Hum Mol Genet , vol.7 , pp. 257-264
    • Kraft, H.G.1    Windegger, M.2    Menzel, H.J.3
  • 22
    • 0033058188 scopus 로고    scopus 로고
    • Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians
    • Scholz M, Kraft HG, Lingenhel A, et al. Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians. Eur J Hum Genet 1999;7:169-78.
    • (1999) Eur J Hum Genet , vol.7 , pp. 169-178
    • Scholz, M.1    Kraft, H.G.2    Lingenhel, A.3
  • 23
    • 0030985016 scopus 로고    scopus 로고
    • Serum distribution of lipoprotein(a) in African Americans and Nigerians: Potential evidence for a genotype-environmental effect
    • Rotimi CN, et al. Serum distribution of lipoprotein(a) in African Americans and Nigerians: potential evidence for a genotype-environmental effect. Genet Epidemiol 1997;14:157-68.
    • (1997) Genet Epidemiol , vol.14 , pp. 157-168
    • Rotimi, C.N.1
  • 24
    • 0000367386 scopus 로고    scopus 로고
    • Choices for healthy outcomes in caring for end stage renal disease
    • Powe NR, Klag MJ, Sadler JH, et al. Choices for healthy outcomes in caring for end stage renal disease. Semin Dial 1996;9:9-11.
    • (1996) Semin Dial , vol.9 , pp. 9-11
    • Powe, N.R.1    Klag, M.J.2    Sadler, J.H.3
  • 25
    • 0036186451 scopus 로고    scopus 로고
    • Race-specific association of lipoprotein(a) with vascular access interventions in hemodialysis patients: The CHOICE Study
    • Astor BC, Eustace JA, Klag MJ, et al. Race-specific association of lipoprotein(a) with vascular access interventions in hemodialysis patients: the CHOICE Study. Kidney Int 2002;61:1115-23.
    • (2002) Kidney Int , vol.61 , pp. 1115-1123
    • Astor, B.C.1    Eustace, J.A.2    Klag, M.J.3
  • 26
    • 0030660620 scopus 로고    scopus 로고
    • Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography
    • Underhill PA, Jin L, Lin AA, et al. Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography. Genome Res 1997;7:996-1005.
    • (1997) Genome Res , vol.7 , pp. 996-1005
    • Underhill, P.A.1    Jin, L.2    Lin, A.A.3
  • 27
    • 0031985152 scopus 로고    scopus 로고
    • Apolipoprotein(a) gene enhancer resides within a LINE element
    • Yang Z, Boffelli D, Boonmark N, et al. Apolipoprotein(a) gene enhancer resides within a LINE element. J Biol Chem 1998;273:891-7.
    • (1998) J Biol Chem , vol.273 , pp. 891-897
    • Yang, Z.1    Boffelli, D.2    Boonmark, N.3
  • 28
    • 17044441930 scopus 로고    scopus 로고
    • Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse
    • Lindblad-Toh K, Winchester E, Daly MJ, et al. Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse. Nat Genet 2000;24:381-6.
    • (2000) Nat Genet , vol.24 , pp. 381-386
    • Lindblad-Toh, K.1    Winchester, E.2    Daly, M.J.3
  • 29
    • 33846127014 scopus 로고    scopus 로고
    • Arlequin Version 2. A software for population genetics data analysis, Genetics and Biometry Laboratory, Switzerland: University of Geneva, 2000
    • Arlequin Version 2. A software for population genetics data analysis, Genetics and Biometry Laboratory, Switzerland: University of Geneva, 2000.
  • 30
    • 0029101292 scopus 로고
    • Multicenter study of lipoprotein(a) and apolipoprotein(a) phenotypes in patients with end-stage renal disease treated by hemodialysis or continuous ambulatory peritoneal dialysis
    • Kronenberg F, Konig P, Neyer U, et al. Multicenter study of lipoprotein(a) and apolipoprotein(a) phenotypes in patients with end-stage renal disease treated by hemodialysis or continuous ambulatory peritoneal dialysis. J Am Soc Nephrol 1995;6:110-20.
    • (1995) J Am Soc Nephrol , vol.6 , pp. 110-120
    • Kronenberg, F.1    Konig, P.2    Neyer, U.3
  • 31
    • 26944462059 scopus 로고    scopus 로고
    • High lipoprotein(a) levels and small apolipoprotein(a) size prospectively predict cardiovascular events in dialysis patients
    • Longenecker JC, Klag MJ, Marcovina SM, et al. High lipoprotein(a) levels and small apolipoprotein(a) size prospectively predict cardiovascular events in dialysis patients. J Am Soc Nephrol 2005;16:1794-802.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1794-1802
    • Longenecker, J.C.1    Klag, M.J.2    Marcovina, S.M.3
  • 32
    • 0033016306 scopus 로고    scopus 로고
    • Sequence polymorphisms in the apolipoprotein(a) gene and their association with lipoprotein(a) levels and myocardial infarction. The ECTIM Study
    • Brazier L, Tiret L, Luc G, et al. Sequence polymorphisms in the apolipoprotein(a) gene and their association with lipoprotein(a) levels and myocardial infarction. The ECTIM Study. Atherosclerosis 1999;144:323-33.
    • (1999) Atherosclerosis , vol.144 , pp. 323-333
    • Brazier, L.1    Tiret, L.2    Luc, G.3
  • 33
    • 0037456772 scopus 로고    scopus 로고
    • The importance of race and ethnic background in biomedical research and clinical practice
    • Burchard EG, Ziv E, Coyle N, et al. The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med 2003;348:1170-5.
    • (2003) N Engl J Med , vol.348 , pp. 1170-1175
    • Burchard, E.G.1    Ziv, E.2    Coyle, N.3
  • 34
    • 84984932946 scopus 로고    scopus 로고
    • Population genetics-making sense out of sequence
    • Chakravarti A. Population genetics-making sense out of sequence. Nat Genet 1999;21(Suppl 1):56-60.
    • (1999) Nat Genet , vol.21 , Issue.SUPPL. 1 , pp. 56-60
    • Chakravarti, A.1
  • 35
    • 0030944935 scopus 로고    scopus 로고
    • Plasma lipoprotein(a) levels and expression of the apolipoprotein(a) gene are dependent on the nucleotide polymorphisms in its 5′-flanking region
    • Suzuki K, Kuriyama M, Saito T, et al. Plasma lipoprotein(a) levels and expression of the apolipoprotein(a) gene are dependent on the nucleotide polymorphisms in its 5′-flanking region. J Clin Invest 1997;99:1361-6.
    • (1997) J Clin Invest , vol.99 , pp. 1361-1366
    • Suzuki, K.1    Kuriyama, M.2    Saito, T.3
  • 36
    • 0032568525 scopus 로고    scopus 로고
    • Sequences within apolipoprotein(a) kringle IV types 6-8 bind directly to low-density lipoprotein and mediate noncovalent association of apolipoprotein(a) with apolipoprotein B-100
    • Gabel BR, Koschinsky ML. Sequences within apolipoprotein(a) kringle IV types 6-8 bind directly to low-density lipoprotein and mediate noncovalent association of apolipoprotein(a) with apolipoprotein B-100. Biochemistry 1998;37:7892-8.
    • (1998) Biochemistry , vol.37 , pp. 7892-7898
    • Gabel, B.R.1    Koschinsky, M.L.2
  • 37
    • 0030978729 scopus 로고    scopus 로고
    • The identification and significance of a Thr→Pro polymorphism in kringle IV type 8 of apolipoprotein(a)
    • Prins J, Leus FR, van der Hoek YY, et al. The identification and significance of a Thr→Pro polymorphism in kringle IV type 8 of apolipoprotein(a). Thromb Haemost 1997;77:949-54.
    • (1997) Thromb Haemost , vol.77 , pp. 949-954
    • Prins, J.1    Leus, F.R.2    van der Hoek, Y.Y.3
  • 38
    • 0028945089 scopus 로고
    • C/T polymorphism in the 5′ untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation
    • Zysow BR, Lindahl GE, Wade DP, et al. C/T polymorphism in the 5′ untranslated region of the apolipoprotein(a) gene introduces an upstream ATG and reduces in vitro translation. Arterioscler Thromb Vasc Biol 1995;15:58-64.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 58-64
    • Zysow, B.R.1    Lindahl, G.E.2    Wade, D.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.