메뉴 건너뛰기




Volumn 83 A, Issue 1, 2013, Pages 48-61

Human mesenchymal stem cells: From immunophenotyping by flow cytometry to clinical applications

Author keywords

Bone marrow; Immunophenotyping; Lipoaspirate; Mesenchymal stem cells; Therapeutic applications

Indexed keywords

CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; FLOW CYTOMETRY; HUMAN; IMMUNOPHENOTYPING; MESENCHYMAL STROMA CELL; METHODOLOGY; REGENERATIVE MEDICINE; REVIEW;

EID: 84871650412     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.22205     Document Type: Review
Times cited : (110)

References (140)
  • 1
    • 79951808622 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Past, present, and future
    • Spencer ND, Gimble JM, Lopez MJ. Mesenchymal stromal cells: Past, present, and future. Vet Surg 2011; 40: 129-139.
    • (2011) Vet Surg , vol.40 , pp. 129-139
    • Spencer, N.D.1    Gimble, J.M.2    Lopez, M.J.3
  • 2
    • 34248332602 scopus 로고    scopus 로고
    • Adipose-derived stem cells for regenerative medicine
    • Gimble JM, Katz AJ, Bunnell BA. Adipose-derived stem cells for regenerative medicine. Circ Res 2007; 100: 1249-1260.
    • (2007) Circ Res , vol.100 , pp. 1249-1260
    • Gimble, J.M.1    Katz, A.J.2    Bunnell, B.A.3
  • 4
    • 77953508180 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation: The state of the art
    • Gyurkocza B, Rezvani A, Storb RF. Allogeneic hematopoietic cell transplantation: The state of the art. Expert Rev Hematol 2010; 3: 285-299.
    • (2010) Expert Rev Hematol , vol.3 , pp. 285-299
    • Gyurkocza, B.1    Rezvani, A.2    Storb, R.F.3
  • 5
    • 74049140758 scopus 로고    scopus 로고
    • Phenotypes of stem cells from diverse origin
    • Tárnok A, Ulrich H, Bocsi J. Phenotypes of stem cells from diverse origin. Cytometry Part A 2010; 77A: 6-10.
    • (2010) Cytometry Part A , vol.77 A , pp. 6-10
    • Tárnok, A.1    Ulrich, H.2    Bocsi, J.3
  • 10
    • 0043127471 scopus 로고    scopus 로고
    • Future and current surgical therapies in Parkinson's disease
    • Betchen SA, Kaplitt M. Future and current surgical therapies in Parkinson's disease. Curr Opin Neurol 2003; 16: 487-493.
    • (2003) Curr Opin Neurol , vol.16 , pp. 487-493
    • Betchen, S.A.1    Kaplitt, M.2
  • 15
    • 19444372143 scopus 로고    scopus 로고
    • Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo
    • Cao Y, Sun Z, Liao L, Meng Y, Han Q, Zhao RC. Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo. Biochem Biophys Res Commun 2005; 332: 370-379.
    • (2005) Biochem Biophys Res Commun , vol.332 , pp. 370-379
    • Cao, Y.1    Sun, Z.2    Liao, L.3    Meng, Y.4    Han, Q.5    Zhao, R.C.6
  • 22
    • 57449096881 scopus 로고    scopus 로고
    • Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta
    • Brooke G, Tong H, Levesque JP, Atkinson K. Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta. Stem Cells Dev 2008; 17: 929-940.
    • (2008) Stem Cells Dev , vol.17 , pp. 929-940
    • Brooke, G.1    Tong, H.2    Levesque, J.P.3    Atkinson, K.4
  • 26
    • 0242690985 scopus 로고    scopus 로고
    • Identification, quantification and isolation of mesenchymal progenitor cells from osteoarthritic synovium by fluorescence automated cell sorting
    • Fickert S, Fiedler J, Brenner RE. Identification, quantification and isolation of mesenchymal progenitor cells from osteoarthritic synovium by fluorescence automated cell sorting. Osteoarthritis Cartilage 2003; 11: 790-800.
    • (2003) Osteoarthritis Cartilage , vol.11 , pp. 790-800
    • Fickert, S.1    Fiedler, J.2    Brenner, R.E.3
  • 31
    • 34147107634 scopus 로고    scopus 로고
    • Concise review: Adipose tissue-derived stromal cells--Basic and clinical implications for novel cell-based therapies
    • Schäffler A, Büchler C. Concise review: Adipose tissue-derived stromal cells--Basic and clinical implications for novel cell-based therapies. Stem Cells 2007; 25: 818-827.
    • (2007) Stem Cells , vol.25 , pp. 818-827
    • Schäffler, A.1    Büchler, C.2
  • 35
    • 59449099378 scopus 로고    scopus 로고
    • An in vivo multimodal imaging study using MRI and PET of stem cell transplantation after myocardial infarction in rats
    • Chapon C, Jackson JS, Aboagye EO, Herlihy AH, Jones WA, Bhakoo KK. An in vivo multimodal imaging study using MRI and PET of stem cell transplantation after myocardial infarction in rats. Mol Imaging Biol 2009; 11: 31-38.
    • (2009) Mol Imaging Biol , vol.11 , pp. 31-38
    • Chapon, C.1    Jackson, J.S.2    Aboagye, E.O.3    Herlihy, A.H.4    Jones, W.A.5    Bhakoo, K.K.6
  • 37
    • 84857324445 scopus 로고    scopus 로고
    • Imaging stem cell differentiation for cell-based tissue repair
    • Lee Z, Dennis J, Welter J, Caplan A. Imaging stem cell differentiation for cell-based tissue repair. Methods Enzymol 2012; 506: 247-263.
    • (2012) Methods Enzymol , vol.506 , pp. 247-263
    • Lee, Z.1    Dennis, J.2    Welter, J.3    Caplan, A.4
  • 40
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • Horwitz EM, Gordon PL, Koo WK, Marx JC, Neel MD, McNall RY, Muul L, Hofmann T. Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone. Proc Natl Acad Sci USA 2002; 99: 8932-8937.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8932-8937
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3    Marx, J.C.4    Neel, M.D.5    McNall, R.Y.6    Muul, L.7    Hofmann, T.8
  • 44
    • 65549127189 scopus 로고    scopus 로고
    • New bone formation by allogeneic mesenchymal stem cell transplantation in a patient with perinatal hypophosphatasia
    • Tadokoro M, Kanai R, Taketani T, Uchio Y, Yamaguchi S, Ohgushi H. New bone formation by allogeneic mesenchymal stem cell transplantation in a patient with perinatal hypophosphatasia. J Pediatr 2009; 154: 924-930.
    • (2009) J Pediatr , vol.154 , pp. 924-930
    • Tadokoro, M.1    Kanai, R.2    Taketani, T.3    Uchio, Y.4    Yamaguchi, S.5    Ohgushi, H.6
  • 45
    • 79959959344 scopus 로고    scopus 로고
    • Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: A case series
    • Pak J. Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: A case series. J Med Case Reports 2011; 5: 296.
    • (2011) J Med Case Reports , vol.5 , pp. 296
    • Pak, J.1
  • 48
    • 21444445838 scopus 로고    scopus 로고
    • Percutaneous autologous bone-marrow grafting for nonunions: Influence of the number and concentration of progenitor cells
    • Hernigou P, Poignard A, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions: Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am 2005; 87: 1430-1437.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 1430-1437
    • Hernigou, P.1    Poignard, A.2    Beaujean, F.3    Rouard, H.4
  • 49
    • 66249096001 scopus 로고    scopus 로고
    • Cartilage homeostasis in health and rheumatic diseases
    • Goldring MB, Marcu KB. Cartilage homeostasis in health and rheumatic diseases. Arthritis Res Ther 2009; 11: 224.
    • (2009) Arthritis Res Ther , vol.11 , pp. 224
    • Goldring, M.B.1    Marcu, K.B.2
  • 50
    • 0035881367 scopus 로고    scopus 로고
    • Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats
    • Chen J, Li Y, Wang L, Lu M, Zhang X, Chopp M. Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats. J Neurol Sci 2001; 189: 49-57.
    • (2001) J Neurol Sci , vol.189 , pp. 49-57
    • Chen, J.1    Li, Y.2    Wang, L.3    Lu, M.4    Zhang, X.5    Chopp, M.6
  • 51
    • 0035479836 scopus 로고    scopus 로고
    • Differentiation potential of adult stem cells
    • Clarke D, Frise'n J. Differentiation potential of adult stem cells. Curr Opin Genet Dev 2001; 11: 575-580.
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 575-580
    • Clarke, D.1    Frise'n, J.2
  • 53
    • 0036022518 scopus 로고    scopus 로고
    • Adult stem cells gradually come of age
    • Prockop DJ. Adult stem cells gradually come of age. Nat Biotechnol 2002; 20: 791-792.
    • (2002) Nat Biotechnol , vol.20 , pp. 791-792
    • Prockop, D.J.1
  • 54
    • 0035798937 scopus 로고    scopus 로고
    • New cells from old
    • Scolding N. New cells from old. Lancet 2001; 357: 329-330.
    • (2001) Lancet , vol.357 , pp. 329-330
    • Scolding, N.1
  • 55
    • 0034809239 scopus 로고    scopus 로고
    • In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP
    • Deng W, Obrocka M, Fischer I, Prockop DJ. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun 2001; 282: 148-152.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 148-152
    • Deng, W.1    Obrocka, M.2    Fischer, I.3    Prockop, D.J.4
  • 56
    • 37749010932 scopus 로고    scopus 로고
    • Enhanced green fluorescent proteinYexpressing human mesenchymal stem cells retain neural marker expression
    • Gordon D, Glover CP, Merrison AM, Uney JB, Scolding NJ. Enhanced green fluorescent proteinYexpressing human mesenchymal stem cells retain neural marker expression. J Neuroimmunol 2008; 193: 59-67.
    • (2008) J Neuroimmunol , vol.193 , pp. 59-67
    • Gordon, D.1    Glover, C.P.2    Merrison, A.M.3    Uney, J.B.4    Scolding, N.J.5
  • 57
    • 0037007985 scopus 로고    scopus 로고
    • Differentiation of adult bone marrow stem cells into neuroprogenitor cells in vitro
    • Kim BJ, Seo JH, Bubien JK, Oh YS. Differentiation of adult bone marrow stem cells into neuroprogenitor cells in vitro. Neuroreport 2002; 13: 1185-1188.
    • (2002) Neuroreport , vol.13 , pp. 1185-1188
    • Kim, B.J.1    Seo, J.H.2    Bubien, J.K.3    Oh, Y.S.4
  • 59
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000; 61: 364-370.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 60
    • 34247583987 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration
    • Bae JS, Han HS, Youn DH, Carter JE, Modo M, Schuchman EH, Jin HK. Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration. Stem Cells 2007; 25: 1307-1316.
    • (2007) Stem Cells , vol.25 , pp. 1307-1316
    • Bae, J.S.1    Han, H.S.2    Youn, D.H.3    Carter, J.E.4    Modo, M.5    Schuchman, E.H.6    Jin, H.K.7
  • 61
    • 56049127384 scopus 로고    scopus 로고
    • Recruitment of endogenous stem cells for tissue repair
    • Zhao J, Zhang N, Prestwich GD, Wen X. Recruitment of endogenous stem cells for tissue repair. Macromol Biosci 2008; 8: 836-842.
    • (2008) Macromol Biosci , vol.8 , pp. 836-842
    • Zhao, J.1    Zhang, N.2    Prestwich, G.D.3    Wen, X.4
  • 62
    • 2342499798 scopus 로고    scopus 로고
    • Bone marrow stromal cells infused into the cerebrospinal fluid promote functional recovery of the injured rat spinal cord with reduced cavity formation
    • Ohta M, Suzuki Y, Noda T, Ejiri Y, Dezawa M, Kataoka K, Chou H, Ishikawa N, Matsumoto N, Iwashita Y, et al. Bone marrow stromal cells infused into the cerebrospinal fluid promote functional recovery of the injured rat spinal cord with reduced cavity formation. Exp Neurol 2004; 187: 266-278.
    • (2004) Exp Neurol , vol.187 , pp. 266-278
    • Ohta, M.1    Suzuki, Y.2    Noda, T.3    Ejiri, Y.4    Dezawa, M.5    Kataoka, K.6    Chou, H.7    Ishikawa, N.8    Matsumoto, N.9    Iwashita, Y.10
  • 63
    • 0035075998 scopus 로고    scopus 로고
    • Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats
    • Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001; 32: 1005-1011.
    • (2001) Stroke , vol.32 , pp. 1005-1011
    • Chen, J.1    Li, Y.2    Wang, L.3    Zhang, Z.4    Lu, D.5    Lu, M.6    Chopp, M.7
  • 64
    • 60549107348 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation for neurodegenerative diseases
    • Torrente Y, Polli E. Mesenchymal stem cell transplantation for neurodegenerative diseases. Cell Transplant 2008; 17: 1103-1113.
    • (2008) Cell Transplant , vol.17 , pp. 1103-1113
    • Torrente, Y.1    Polli, E.2
  • 65
    • 0036703491 scopus 로고    scopus 로고
    • Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells
    • Akiyama Y, Radtke C, Kocsis JD. Remyelination of the rat spinal cord by transplantation of identified bone marrow stromal cells. J Neurosci 2002; 22: 6623-6630.
    • (2002) J Neurosci , vol.22 , pp. 6623-6630
    • Akiyama, Y.1    Radtke, C.2    Kocsis, J.D.3
  • 66
    • 0034948215 scopus 로고    scopus 로고
    • Transplantation of an acutely isolated bone marrow fraction repairs demyelinated adult rat spinal cord axons
    • Sasaki M, Honmou O, Akiyama Y, Uede T, Hashi K, Kocsis JD. Transplantation of an acutely isolated bone marrow fraction repairs demyelinated adult rat spinal cord axons. Glia 2001; 35: 26-34.
    • (2001) Glia , vol.35 , pp. 26-34
    • Sasaki, M.1    Honmou, O.2    Akiyama, Y.3    Uede, T.4    Hashi, K.5    Kocsis, J.D.6
  • 68
    • 0034637810 scopus 로고    scopus 로고
    • Spinal cord injury in rat: Treatment with bone marrow stromal cell transplantation
    • Chopp M, Zhang XH, Li Y, Wang L, Chen J, Lu D, Lu M, Rosenblum M. Spinal cord injury in rat: Treatment with bone marrow stromal cell transplantation. Neuroreport 2000; 11: 3001-3005.
    • (2000) Neuroreport , vol.11 , pp. 3001-3005
    • Chopp, M.1    Zhang, X.H.2    Li, Y.3    Wang, L.4    Chen, J.5    Lu, D.6    Lu, M.7    Rosenblum, M.8
  • 69
    • 0035909960 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    • Li Y, Chen J, Wang L, Zhang L, Lu M, Chopp M. Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson's disease. Neurosci Lett 2001; 316: 67-70.
    • (2001) Neurosci Lett , vol.316 , pp. 67-70
    • Li, Y.1    Chen, J.2    Wang, L.3    Zhang, L.4    Lu, M.5    Chopp, M.6
  • 70
    • 0033544028 scopus 로고    scopus 로고
    • Multipotential marrow stromal cells transduced to produce L-DOPA: Engraftment in a rat model of Parkinson disease
    • Schwarz EJ, Alexander GM, Prockop DJ, Azizi SA. Multipotential marrow stromal cells transduced to produce L-DOPA: Engraftment in a rat model of Parkinson disease. Hum Gene Ther 1999; 10: 2539-2549.
    • (1999) Hum Gene Ther , vol.10 , pp. 2539-2549
    • Schwarz, E.J.1    Alexander, G.M.2    Prockop, D.J.3    Azizi, S.A.4
  • 73
    • 0035984714 scopus 로고    scopus 로고
    • Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
    • Simonsen JL, Rosada C, Serakinci N, Justesen J, Stenderup K, Rattan SI, Jensen TG, Kassem M. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotechnol 2002; 20: 592-599.
    • (2002) Nat Biotechnol , vol.20 , pp. 592-599
    • Simonsen, J.L.1    Rosada, C.2    Serakinci, N.3    Justesen, J.4    Stenderup, K.5    Rattan, S.I.6    Jensen, T.G.7    Kassem, M.8
  • 74
    • 79956037142 scopus 로고    scopus 로고
    • Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's disease
    • Klinge PM, Harmening K, Miller MC, Heile A, Wallrapp C, Geigle P, Brinker T. Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's disease. Neurosci Lett 2011; 497: 6-10.
    • (2011) Neurosci Lett , vol.497 , pp. 6-10
    • Klinge, P.M.1    Harmening, K.2    Miller, M.C.3    Heile, A.4    Wallrapp, C.5    Geigle, P.6    Brinker, T.7
  • 75
    • 77954189278 scopus 로고    scopus 로고
    • Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NF-kappaB mediated increase in Interleukin 6 (IL-6) production
    • Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, Cox CSJr. Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NF-kappaB mediated increase in Interleukin 6 (IL-6) production. Stem Cells Dev 2010; 19: 867-876.
    • (2010) Stem Cells Dev , vol.19 , pp. 867-876
    • Walker, P.A.1    Harting, M.T.2    Jimenez, F.3    Shah, S.K.4    Pati, S.5    Dash, P.K.6    Cox Jr, C.S.7
  • 76
    • 0345580623 scopus 로고    scopus 로고
    • Cytokine actions in the central nervous system
    • Benveniste EN. Cytokine actions in the central nervous system. Cytokine Growth Factor Rev 1998; 9: 259-275.
    • (1998) Cytokine Growth Factor Rev , vol.9 , pp. 259-275
    • Benveniste, E.N.1
  • 77
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008; 8: 726-736.
    • (2008) Nat Rev Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 78
    • 0036739256 scopus 로고    scopus 로고
    • Remyelination of the spinal cord following intravenous delivery of bone marrow cells
    • Akiyama Y, Radtke C, Honmou O, Kocsis JD. Remyelination of the spinal cord following intravenous delivery of bone marrow cells. Glia 2002; 39: 229-236.
    • (2002) Glia , vol.39 , pp. 229-236
    • Akiyama, Y.1    Radtke, C.2    Honmou, O.3    Kocsis, J.D.4
  • 79
    • 0242385633 scopus 로고    scopus 로고
    • Comparative analysis of remyelinating potential of focal and intravenous administration of autologous bone marrow cells into the rat demyelinated spinal cord
    • Inoue M, Honmou O, Oka S, Houkin K, Hashi K, Kocsis JD. Comparative analysis of remyelinating potential of focal and intravenous administration of autologous bone marrow cells into the rat demyelinated spinal cord. Glia 2003; 44: 111-118.
    • (2003) Glia , vol.44 , pp. 111-118
    • Inoue, M.1    Honmou, O.2    Oka, S.3    Houkin, K.4    Hashi, K.5    Kocsis, J.D.6
  • 81
    • 65649113921 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis
    • Bai L, Lennon DP, Eaton V, Maier K, Caplan AI, Miller SD, Miller RH. Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis. Glia 2009; 57: 1192-1203.
    • (2009) Glia , vol.57 , pp. 1192-1203
    • Bai, L.1    Lennon, D.P.2    Eaton, V.3    Maier, K.4    Caplan, A.I.5    Miller, S.D.6    Miller, R.H.7
  • 82
    • 33846935754 scopus 로고    scopus 로고
    • Human mesenchymal stem cells signals regulate neural stem cell fate
    • Bai L, Caplan A, Lennon D, Miller RH. Human mesenchymal stem cells signals regulate neural stem cell fate. Neurochem Res 2007; 32: 353-362.
    • (2007) Neurochem Res , vol.32 , pp. 353-362
    • Bai, L.1    Caplan, A.2    Lennon, D.3    Miller, R.H.4
  • 84
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci USA 1999; 96: 10711-10716.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 85
    • 0038281370 scopus 로고    scopus 로고
    • Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates
    • Devine SM, Cobbs C, Jennings M, Bartholomew A, Hoffman R. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates. Blood 2003; 101: 2999-3001.
    • (2003) Blood , vol.101 , pp. 2999-3001
    • Devine, S.M.1    Cobbs, C.2    Jennings, M.3    Bartholomew, A.4    Hoffman, R.5
  • 86
    • 0036546066 scopus 로고    scopus 로고
    • New concepts in the immunopathogenesis of multiple sclerosis
    • Hemmer B, Archelos JJ, Hartung HP. New concepts in the immunopathogenesis of multiple sclerosis. Nat Rev Neurosci 2002; 3: 291-301.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 291-301
    • Hemmer, B.1    Archelos, J.J.2    Hartung, H.P.3
  • 87
    • 0036260390 scopus 로고    scopus 로고
    • Pathogenesis of multiple sclerosis: An update on immunology
    • Hemmer B, Cepok S, Nessler S, Sommer N. Pathogenesis of multiple sclerosis: An update on immunology. Curr Opin Neurol 2002; 15: 227-231.
    • (2002) Curr Opin Neurol , vol.15 , pp. 227-231
    • Hemmer, B.1    Cepok, S.2    Nessler, S.3    Sommer, N.4
  • 88
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination. Ann Neurol 2000; 47: 707-717.
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Brück, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 93
    • 0034589149 scopus 로고    scopus 로고
    • Transplantation in the rat model of Parkinson's disease: Ectopic versus homotopic graft placement
    • Winkler C, Kirik D, Björklund A, Dunnett SB. Transplantation in the rat model of Parkinson's disease: Ectopic versus homotopic graft placement. Prog Brain Res 2000; 127: 233-265.
    • (2000) Prog Brain Res , vol.127 , pp. 233-265
    • Winkler, C.1    Kirik, D.2    Björklund, A.3    Dunnett, S.B.4
  • 94
    • 0002645391 scopus 로고
    • Functional studies of neural grafts in Parkinsonian primates
    • Annett LE. Functional studies of neural grafts in Parkinsonian primates. Transl Res 1994; 71-102.
    • (1994) Transl Res , pp. 71-102
    • Annett, L.E.1
  • 95
    • 79251475888 scopus 로고    scopus 로고
    • Bone marrow stromal cells as replacement cells for Parkinson's disease: Generation of an anatomical but not functional neuronal phenotype
    • Thomas MG, Stone L, Evill L, Ong S, Ziman M, Hool L. Bone marrow stromal cells as replacement cells for Parkinson's disease: Generation of an anatomical but not functional neuronal phenotype. Transl Res 2011; 157: 56-63.
    • (2011) Transl Res , vol.157 , pp. 56-63
    • Thomas, M.G.1    Stone, L.2    Evill, L.3    Ong, S.4    Ziman, M.5    Hool, L.6
  • 96
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 2005; 57: 874-882.
    • (2005) Ann Neurol , vol.57 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3    Lee, G.4
  • 98
    • 67650845362 scopus 로고    scopus 로고
    • Intravenous mesenchymal stem cell therapy for traumatic brain injury Intravenous mesenchymal stem cell therapy for traumatic brain injury
    • Harting MT, Jimenez F, Xue H, Fischer UM, Baumgartner J, Dash PK, Cox CS. Intravenous mesenchymal stem cell therapy for traumatic brain injury Intravenous mesenchymal stem cell therapy for traumatic brain injury. J Neurosurg 2009; 110: 1189-1197.
    • (2009) J Neurosurg , vol.110 , pp. 1189-1197
    • Harting, M.T.1    Jimenez, F.2    Xue, H.3    Fischer, U.M.4    Baumgartner, J.5    Dash, P.K.6    Cox, C.S.7
  • 101
    • 2442656364 scopus 로고    scopus 로고
    • Functional recovery in chronic paraplegia after bone marrow stromal cells transplantation
    • Zurita M, Vaquero J. Functional recovery in chronic paraplegia after bone marrow stromal cells transplantation. Neuroreport 2004; 15: 1105-1108.
    • (2004) Neuroreport , vol.15 , pp. 1105-1108
    • Zurita, M.1    Vaquero, J.2
  • 102
    • 42149092238 scopus 로고    scopus 로고
    • Current status of experimental cell replacement approaches to spinal cord injury
    • Eftekharpour E, Karimi-Abdolrezaee S, Fehlings MG. Current status of experimental cell replacement approaches to spinal cord injury. Neurosurg Focus 2008; 24: E19.
    • (2008) Neurosurg Focus , vol.24
    • Eftekharpour, E.1    Karimi-Abdolrezaee, S.2    Fehlings, M.G.3
  • 105
  • 106
    • 76249107497 scopus 로고    scopus 로고
    • Mortalidade Cardiovascular por Sexo e Faixa Etária em São Paulo, Brasil: 1996 a 1998 e 2003 a 2005
    • Farias N, Souza JMP, Laurenti R, Alencar SM. Mortalidade Cardiovascular por Sexo e Faixa Etária em São Paulo, Brasil: 1996 a 1998 e 2003 a 2005. Arq Bras Cardiol 2009; 93: 498-505.
    • (2009) Arq Bras Cardiol , vol.93 , pp. 498-505
    • Farias, N.1    Souza, J.M.P.2    Laurenti, R.3    Alencar, S.M.4
  • 107
    • 40949086056 scopus 로고    scopus 로고
    • Heart failure incidence and survival (from the Atherosclerosis Risk in Communities study)
    • Loehr LR, Rosamond WD, Chang PP, Folsom AR, Chambless LE. Heart failure incidence and survival (from the Atherosclerosis Risk in Communities study). Am J Cardiol 2008; 101: 1016-1022.
    • (2008) Am J Cardiol , vol.101 , pp. 1016-1022
    • Loehr, L.R.1    Rosamond, W.D.2    Chang, P.P.3    Folsom, A.R.4    Chambless, L.E.5
  • 110
    • 33847302010 scopus 로고    scopus 로고
    • Optimal temporal delivery of bone marrow mesenchymal stem cells in rats with myocardial infarction
    • Hu X, Wang J, Chen J, Luo R, He A, Xie X, Li J. Optimal temporal delivery of bone marrow mesenchymal stem cells in rats with myocardial infarction. Eur J Cardiothorac Surg 2007; 31: 438-443.
    • (2007) Eur J Cardiothorac Surg , vol.31 , pp. 438-443
    • Hu, X.1    Wang, J.2    Chen, J.3    Luo, R.4    He, A.5    Xie, X.6    Li, J.7
  • 111
    • 21744446566 scopus 로고    scopus 로고
    • Washout of transplanted cells from the heart: A potential new hurdle for cell transplantation therapy
    • Dow J, Simkhovich BZ, Kedes L, Kloner RA. Washout of transplanted cells from the heart: A potential new hurdle for cell transplantation therapy. Cardiovasc Res 2005; 67: 301-307.
    • (2005) Cardiovasc Res , vol.67 , pp. 301-307
    • Dow, J.1    Simkhovich, B.Z.2    Kedes, L.3    Kloner, R.A.4
  • 112
    • 0034971110 scopus 로고    scopus 로고
    • Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies
    • Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, Murry CE. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 2001; 33: 907-921.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 907-921
    • Zhang, M.1    Methot, D.2    Poppa, V.3    Fujio, Y.4    Walsh, K.5    Murry, C.E.6
  • 113
    • 78650069106 scopus 로고    scopus 로고
    • Preservation of the cardiac function in infarcted rat hearts by the transplantation of adipose-derived stem cells with injectable fibrin scaffolds
    • Zhang X, Wang H, Ma X, Adila A, Wang B, Liu F, Chen B, Wang C, Ma Y. Preservation of the cardiac function in infarcted rat hearts by the transplantation of adipose-derived stem cells with injectable fibrin scaffolds. Exp Biol Med (Maywood) 2010; 235: 1505-1515.
    • (2010) Exp Biol Med (Maywood) , vol.235 , pp. 1505-1515
    • Zhang, X.1    Wang, H.2    Ma, X.3    Adila, A.4    Wang, B.5    Liu, F.6    Chen, B.7    Wang, C.8    Ma, Y.9
  • 115
    • 70350514247 scopus 로고    scopus 로고
    • Cell sheet-based myocardial tissue engineering: new hope for damaged heart rescue
    • Shimizu T, Sekine H, Yamato M, Okano T. Cell sheet-based myocardial tissue engineering: new hope for damaged heart rescue. Curr Pharm Des 2009; 15: 2807-2814.
    • (2009) Curr Pharm Des , vol.15 , pp. 2807-2814
    • Shimizu, T.1    Sekine, H.2    Yamato, M.3    Okano, T.4
  • 117
  • 120
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002; 105: 93-98.
    • (2002) Circulation , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 121
    • 0042416929 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model
    • Davani S, Marandin A, Mersin N, Royer B, Kantelip B, Herve P, Etievent JP, Kantelip JP. Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model. Circulation 2003; 108 (Suppl 1): II253-II258.
    • (2003) Circulation , vol.108 , Issue.SUPPL 1
    • Davani, S.1    Marandin, A.2    Mersin, N.3    Royer, B.4    Kantelip, B.5    Herve, P.6    Etievent, J.P.7    Kantelip, J.P.8
  • 125
    • 0037337952 scopus 로고    scopus 로고
    • Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes
    • Rangappa S, Fen C, Lee EH, Bongso A, Sim EK. Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. Ann Thorac Surg 2003; 75: 775-779.
    • (2003) Ann Thorac Surg , vol.75 , pp. 775-779
    • Rangappa, S.1    Fen, C.2    Lee, E.H.3    Bongso, A.4    Sim, E.K.5
  • 127
    • 3042856796 scopus 로고    scopus 로고
    • Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro
    • Xu W, Zhang X, Qian H, Zhu W, Sun X, Hu J, Zhou H, Chen Y. Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro. Exp Biol Med (Maywood) 2004; 229: 623-631.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 623-631
    • Xu, W.1    Zhang, X.2    Qian, H.3    Zhu, W.4    Sun, X.5    Hu, J.6    Zhou, H.7    Chen, Y.8
  • 128
    • 20444465738 scopus 로고    scopus 로고
    • Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model
    • Yoon J, Min BG, Kim YH, Shim WJ, Ro YM, Lim DS. Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model. Acta Cardiol 2005; 60: 277-284.
    • (2005) Acta Cardiol , vol.60 , pp. 277-284
    • Yoon, J.1    Min, B.G.2    Kim, Y.H.3    Shim, W.J.4    Ro, Y.M.5    Lim, D.S.6
  • 130
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, Grisanti S, Gianni AM. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002; 99: 3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 131
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • Ren G, Zhang L, Zhao X, Xu G, Zhang Y, Roberts AI, Zhao RC, Shi Y. Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008; 2: 141-150.
    • (2008) Cell Stem Cell , vol.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3    Xu, G.4    Zhang, Y.5    Roberts, A.I.6    Zhao, R.C.7    Shi, Y.8
  • 132
    • 67649909142 scopus 로고    scopus 로고
    • The antiapoptotic effect of mesenchymal stem cell transplantation on ischemic myocardium is enhanced by anoxic preconditioning
    • He A, Jiang Y, Gui C, Sun Y, Li J, Wang JA. The antiapoptotic effect of mesenchymal stem cell transplantation on ischemic myocardium is enhanced by anoxic preconditioning. Can J Cardiol 2009; 25: 353-358.
    • (2009) Can J Cardiol , vol.25 , pp. 353-358
    • He, A.1    Jiang, Y.2    Gui, C.3    Sun, Y.4    Li, J.5    Wang, J.A.6
  • 133
    • 0034526510 scopus 로고    scopus 로고
    • Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF
    • Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H. Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J Clin Invest 2000; 106: 1511-1519.
    • (2000) J Clin Invest , vol.106 , pp. 1511-1519
    • Nakamura, T.1    Mizuno, S.2    Matsumoto, K.3    Sawa, Y.4    Matsuda, H.5
  • 135
    • 33749334622 scopus 로고    scopus 로고
    • Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-I in response to TNF by a p38 MAPK-dependent mechanism
    • Wang M, Crisostomo PR, Herring C, Meldrum KK, Meldrum DR. Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-I in response to TNF by a p38 MAPK-dependent mechanism. Am J Physiol Regul Integr Comp Physiol 2006; 291: R880-R884.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Wang, M.1    Crisostomo, P.R.2    Herring, C.3    Meldrum, K.K.4    Meldrum, D.R.5
  • 136
    • 34748845732 scopus 로고    scopus 로고
    • Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis
    • Hung SC, Pochampally RR, Chen SC, Hsu SC, Prockop DJ. Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis. Stem Cells 2007; 25: 2363-2370.
    • (2007) Stem Cells , vol.25 , pp. 2363-2370
    • Hung, S.C.1    Pochampally, R.R.2    Chen, S.C.3    Hsu, S.C.4    Prockop, D.J.5
  • 138
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, Dzau VJ. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 2003; 9: 1195-1201.
    • (2003) Nat Med , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6    Dzau, V.J.7
  • 139
    • 47149102903 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature
    • Au P, Tam J, Fukumura D, Jain RK. Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood 2008; 111: 4551-4558.
    • (2008) Blood , vol.111 , pp. 4551-4558
    • Au, P.1    Tam, J.2    Fukumura, D.3    Jain, R.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.