Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration

Cell Stem Cell

Volumn 10, Issue 3, 2012, Pages 259-272

  Park, Dongsu ^a,c,e   Spencer, Joel A ^b,c   Koh, Bong Ihn ^a,c   Kobayashi, Tatsuya ^b   Fujisaki, Joji ^b,c   Clemens, Thomas L ^d   Lin, Charles P ^b,c   Kronenberg, Henry M ^b   Scadden, David T ^a,c,e  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OSTEOCALCIN; TRANSCRIPTION FACTOR OSTERIX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE REGENERATION; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CELL TYPE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; FEMALE; FRACTURE HEALING; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROGENY; STROMA CELL;

ANIMALS; BONE AND BONES; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; FRACTURE HEALING; HUMANS; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; OSTEOBLASTS; STEM CELL TRANSPLANTATION;

ANIMALIA;

EID: 84863229757     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.02.003     Document Type: Article

References (33)

1. P. Bianco, P.G. Robey, and P.J. Simmons Mesenchymal stem cells: revisiting history, concepts, and assays Cell Stem Cell 2 2008 313 319 (Pubitemid 351467394)
2. T. Buch, F.L. Heppner, C. Tertilt, T.J. Heinen, M. Kremer, F.T. Wunderlich, S. Jung, and A. Waisman A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration Nat. Methods 2 2005 419 426 (Pubitemid 40916560)
3. A.I. Caplan Mesenchymal stem cells J. Orthop. Res. 9 1991 641 650
4. A.I. Caplan, and D. Correa The MSC: An Injury Drugstore Cell Stem Cell 9 2011 11 15
5. C.K. Chan, C.C. Chen, C.A. Luppen, J.B. Kim, A.T. DeBoer, K. Wei, J.A. Helms, C.J. Kuo, D.L. Kraft, and I.L. Weissman Endochondral ossification is required for haematopoietic stem-cell niche formation Nature 457 2009 490 494
6. M. Crisan, S. Yap, L. Casteilla, C.W. Chen, M. Corselli, T.S. Park, G. Andriolo, B. Sun, B. Zheng, and L. Zhang A perivascular origin for mesenchymal stem cells in multiple human organs Cell Stem Cell 3 2008 301 313
7. S.L. Dallas, and L.F. Bonewald Dynamics of the transition from osteoblast to osteocyte Ann. N Y Acad. Sci. 1192 2010 437 443
8. M. Dominici, V. Rasini, R. Bussolari, X. Chen, T.J. Hofmann, C. Spano, D. Bernabei, E. Veronesi, F. Bertoni, and P. Paolucci Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation Blood 114 2009 2333 2343
9. Y. Dor, J. Brown, O.I. Martinez, and D.A. Melton Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation Nature 429 2004 41 46 (Pubitemid 38620543)
10. P. Ducy, C. Desbois, B. Boyce, G. Pinero, B. Story, C. Dunstan, E. Smith, J. Bonadio, S. Goldstein, and C. Gundberg Increased bone formation in osteocalcin-deficient mice Nature 382 1996 448 452 (Pubitemid 26264860)
11. G.Z. Eghbali-Fatourechi, J. Lamsam, D. Fraser, D. Nagel, B.L. Riggs, and S. Khosla Circulating osteoblast-lineage cells in humans N. Engl. J. Med. 352 2005 1959 1966 (Pubitemid 40638366)
12. A.J. Friedenstein, R.K. Chailakhyan, N.V. Latsinik, A.F. Panasyuk, and I.V. Keiliss-Borok Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo Transplantation 17 1974 331 340
13. R.L. Jilka, R.S. Weinstein, T. Bellido, A.M. Parfitt, and S.C. Manolagas Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines J. Bone Miner. Res. 13 1998 793 802 (Pubitemid 28224195)
14. Z. Kalajzic, H. Li, L.P. Wang, X. Jiang, K. Lamothe, D.J. Adams, H.L. Aguila, D.W. Rowe, and I. Kalajzic Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population Bone 43 2008 501 510
15. M.J. Kiel, O.H. Yilmaz, T. Iwashita, O.H. Yilmaz, C. Terhorst, and S.J. Morrison SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells Cell 121 2005 1109 1121 (Pubitemid 40884400)
16. E. Lana-Elola, R. Rice, A.E. Grigoriadis, and D.P. Rice Cell fate specification during calvarial bone and suture development Dev. Biol. 311 2007 335 346 (Pubitemid 350046530)
17. N.K. Lee, H. Sowa, E. Hinoi, M. Ferron, J.D. Ahn, C. Confavreux, R. Dacquin, P.J. Mee, M.D. McKee, and D.Y. Jung Endocrine regulation of energy metabolism by the skeleton Cell 130 2007 456 469 (Pubitemid 47208519)
18. P. Leucht, J.B. Kim, R. Wazen, J.A. Currey, A. Nanci, J.B. Brunski, and J.A. Helms Effect of mechanical stimuli on skeletal regeneration around implants Bone 40 2007 919 930 (Pubitemid 46389645)
19. L. Li, and H. Clevers Coexistence of quiescent and active adult stem cells in mammals Science 327 2010 542 545
20. C. Lo Celso, H.E. Fleming, J.W. Wu, C.X. Zhao, S. Miake-Lye, J. Fujisaki, D. Côté, D.W. Rowe, C.P. Lin, and D.T. Scadden Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche Nature 457 2009 92 96
21. C. Maes, T. Kobayashi, M.K. Selig, S. Torrekens, S.I. Roth, S. Mackem, G. Carmeliet, and H.M. Kronenberg Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels Dev. Cell 19 2010 329 344
22. C.A. McCulloch, and J.N. Heersche Lifetime of the osteoblast in mouse periodontium Anat. Rec. 222 1988 128 135
23. S. Méndez-Ferrer, T.V. Michurina, F. Ferraro, A.R. Mazloom, B.D. Macarthur, S.A. Lira, D.T. Scadden, A. Ma'ayan, G.N. Enikolopov, and P.S. Frenette Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Nature 466 2010 829 834
24. S. Morikawa, Y. Mabuchi, Y. Kubota, Y. Nagai, K. Niibe, E. Hiratsu, S. Suzuki, C. Miyauchi-Hara, N. Nagoshi, and T. Sunabori Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow J. Exp. Med. 206 2009 2483 2496
25. S. Otsuru, K. Tamai, T. Yamazaki, H. Yoshikawa, and Y. Kaneda Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway Stem Cells 26 2008 223 234
26. M. Owen, and S. MacPherson Cell Population Kinetics of an Osteogenic Tissue. Ii J. Cell Biol. 19 1963 33 44
27. M.H. Raaijmakers, S. Mukherjee, S. Guo, S. Zhang, T. Kobayashi, J.A. Schoonmaker, B.L. Ebert, F. Al-Shahrour, R.P. Hasserjian, and E.O. Scadden Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia Nature 464 2010 852 857
28. S.J. Rodda, and A.P. McMahon Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors Development 133 2006 3231 3244 (Pubitemid 44404346)
29. B. Sacchetti, A. Funari, S. Michienzi, S. Di Cesare, S. Piersanti, I. Saggio, E. Tagliafico, S. Ferrari, P.G. Robey, M. Riminucci, and P. Bianco Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment Cell 131 2007 324 336 (Pubitemid 47592917)
30. A. Schindeler, M.M. McDonald, P. Bokko, and D.G. Little Bone remodeling during fracture repair: The cellular picture Semin. Cell Dev. Biol. 19 2008 459 466
31. D.A. Sipkins, X. Wei, J.W. Wu, J.M. Runnels, D. Côté, T.K. Means, A.D. Luster, D.T. Scadden, and C.P. Lin In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment Nature 435 2005 969 973 (Pubitemid 40896324)
32. C.R. Walkley, G.H. Olsen, S. Dworkin, S.A. Fabb, J. Swann, G.A. McArthur, S.V. Westmoreland, P. Chambon, D.T. Scadden, and L.E. Purton A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency Cell 129 2007 1097 1110 (Pubitemid 46908696)
33. C.R. Walkley, J.M. Shea, N.A. Sims, L.E. Purton, and S.H. Orkin Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment Cell 129 2007 1081 1095 (Pubitemid 46908695)