Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis

GLIA

Volumn 57, Issue 11, 2009, Pages 1192-1203

  Bai, Lianhua ^a   Lennon, Donald P ^a   Eaton, Valerie ^b   Maier, Kari ^a   Caplan, Arnold I ^a   Miller, Stephen D ^b   Miller, Robert H ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Differentiation; Immune regulation; Mesenchymal stem cells; Migration; Neurons; Oligodendrocytes; Repair

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PROTEOLIPID PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BONE MARROW CELL; CELL FATE; CELL LINEAGE; CELL MIGRATION; CELL POLARITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; DISEASE COURSE; DISEASE MODEL; FEMALE; IMMUNE RESPONSE; IMMUNOMODULATION; INFLAMMATORY CELL; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; MULTIPLE SCLEROSIS; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM INJURY; NEUROPROTECTION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; TH1 CELL; TH17 CELL; TH2 CELL;

ANIMALS; BONE MARROW CELLS; BRAIN; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HUMANS; INTERLEUKIN-17; INTERLEUKIN-4; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; SPINAL CORD; T-LYMPHOCYTES; TH1 CELLS; TH2 CELLS;

EID: 65649113921     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20841     Document Type: Article

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