-
1
-
-
83755219473
-
Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
-
Molodecky NA, Soon IS, Rabi DM, et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012;142:46-54.
-
(2012)
Gastroenterology
, vol.142
, pp. 46-54
-
-
Molodecky, N.A.1
Soon, I.S.2
Rabi, D.M.3
-
3
-
-
78650097770
-
Genetics in twins with Crohn's disease: Less pronounced than previously believed?
-
Halfvarson J. Genetics in twins with Crohn's disease: Less pronounced than previously believed? Inflamm Bowel Dis 2011;17:6-12.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 6-12
-
-
Halfvarson, J.1
-
4
-
-
0033916388
-
Epigenetics of inflammatory bowel disease
-
DOI 10.1136/gut.47.2.302
-
Petronis A, Petroniene R. Epigenetics of inflammatory bowel disease. Gut 2000;47:302-6. (Pubitemid 30489779)
-
(2000)
Gut
, vol.47
, Issue.2
, pp. 302-306
-
-
Petronis, A.1
Petroniene, R.2
-
5
-
-
47949106374
-
Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study
-
Spehlmann ME, Begun AZ, Burghardt J, Lepage P, Raedler A, Schreiber S. Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study. Inflamm Bowel Dis 2008;14:968-76.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 968-976
-
-
Spehlmann, M.E.1
Begun, A.Z.2
Burghardt, J.3
Lepage, P.4
Raedler, A.5
Schreiber, S.6
-
6
-
-
33644647470
-
Disease concordance, zygosity, and NOD2/CARD15 status: Follow-up of a population-based cohort of Danish twins with inflammatory bowel disease
-
Jess T, Riis L, Jespersgaard C, et al. Disease concordance, zygosity, and NOD2/CARD15 status: Follow-up of a population-based cohort of Danish twins with inflammatory bowel disease. Am J Gastroenterol 2005;100:2486-92.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2486-2492
-
-
Jess, T.1
Riis, L.2
Jespersgaard, C.3
-
7
-
-
33646806090
-
Concordance, disease progression, and heritability of coeliac disease in Italian twins
-
Nistico L, Fagnani C, Coto I, et al. Concordance, disease progression, and heritability of coeliac disease in Italian twins. Gut 2006;55:803-8.
-
(2006)
Gut
, vol.55
, pp. 803-808
-
-
Nistico, L.1
Fagnani, C.2
Coto, I.3
-
8
-
-
33845381942
-
Irritable bowel syndrome in twins: Genes and environment
-
DOI 10.1136/gut.2006.097287
-
Bengtson MB, Ronning T, Vatn MH, Harris JR. Irritable bowel syndrome in twins: Genes and environment. Gut 2006;55:1754-9. (Pubitemid 44893573)
-
(2006)
Gut
, vol.55
, Issue.12
, pp. 1754-1759
-
-
Bengtson, M.-B.1
Ronning, T.2
Vatn, M.H.3
Harris, J.R.4
-
9
-
-
21344437297
-
Genetic influences in irritable bowel syndrome: A twin study
-
DOI 10.1111/j.1572-0241.2005.41700.x
-
Mohammed I, Cherkas LF, Riley SA, Spector TD, Trudgill NJ. Genetic influences in irritable bowel syndrome: A twin study. Am J Gastroenterol 2005;100:1340-4. (Pubitemid 40904359)
-
(2005)
American Journal of Gastroenterology
, vol.100
, Issue.6
, pp. 1340-1344
-
-
Mohammed, I.1
Cherkas, L.F.2
Riley, S.A.3
Spector, T.D.4
Trudgill, N.J.5
-
10
-
-
79960324428
-
Revisiting genome wide association studies (GWAS) in coeliac disease: Replication study in Spanish population and expression analysis of candidate genes
-
Plaza-Izurieta L, Castellanos-Rubio A, Irastorza I, et al. Revisiting genome wide association studies (GWAS) in coeliac disease: Replication study in Spanish population and expression analysis of candidate genes. J Med Genet 2011;48:493-6.
-
(2011)
J Med Genet
, vol.48
, pp. 493-496
-
-
Plaza-Izurieta, L.1
Castellanos-Rubio, A.2
Irastorza, I.3
-
11
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010;42:1118-25.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
12
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011;43:246-52.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
13
-
-
77949845957
-
Genetic approaches to functional gastrointestinal disorders
-
Saito YA, Mitra N, Mayer EA. Genetic approaches to functional gastrointestinal disorders. Gastroenterology 2010;138:1276-85.
-
(2010)
Gastroenterology
, vol.138
, pp. 1276-1285
-
-
Saito, Y.A.1
Mitra, N.2
Mayer, E.A.3
-
14
-
-
1842666807
-
NOD2 3020insC frameshift mutation is not associated with inflammatory bowel disease in Chinese patients of Han nationality
-
Guo QS, Xia B, Jiang Y, Qu Y, Li J. NOD2 3020insC frameshift mutation is not associated with inflammatory bowel disease in Chinese patients of Han nationality. World J Gastroenterol 2004;10:1069-71. (Pubitemid 38461397)
-
(2004)
World Journal of Gastroenterology
, vol.10
, Issue.7
, pp. 1069-1071
-
-
Guo, Q.-S.1
Xia, B.2
Jiang, Y.3
Qu, Y.4
Li, J.5
-
15
-
-
0036306951
-
Lack of common NOD2 variants in Japanese patients with Crohn's disease
-
DOI 10.1053/gast.2002.34155
-
Inoue N, Tamura K, Kinouchi Y, et al. Lack of common NOD2 variants in Japanese patients with Crohn's disease. Gastroenterology 2002;123:86-91. (Pubitemid 34747528)
-
(2002)
Gastroenterology
, vol.123
, Issue.1
, pp. 86-91
-
-
Inoue, N.1
Tamura, K.2
Kinouchi, Y.3
Fukuda, Y.4
Takahashi, S.5
Ogura, Y.6
Inohara, N.7
Nuez, G.8
Kishi, Y.9
Koike, Y.10
Shimosegawa, T.11
Shimoyama, T.12
Hibi, T.13
-
16
-
-
33744812482
-
NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene polymorphisms in Turkish patients with inflammatory bowel disease
-
DOI 10.1007/s00535-005-1780-z
-
Ozen SC, Dagli U, Kilic MY, et al. NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene polymorphisms in Turkish patients with inflammatory bowel disease. J Gastroenterol 2006;41:304-10. (Pubitemid 43834372)
-
(2006)
Journal of Gastroenterology
, vol.41
, Issue.4
, pp. 304-310
-
-
Ozen, S.C.1
Dagli, U.2
Kilic, M.Y.3
Toruner, M.4
Celik, Y.5
Ozkan, M.6
Soykan, I.7
Cetinkaya, H.8
Ulker, A.9
Ozden, A.10
Bozdayi, A.M.11
-
17
-
-
79551652513
-
An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians
-
Juyal G, Prasad P, Senapati S, et al. An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians. PLoS ONE 2011;6:e16565.
-
(2011)
PLoS ONE
, vol.6
-
-
Juyal, G.1
Prasad, P.2
Senapati, S.3
-
18
-
-
79953855563
-
Does the incidence of IBD increase when persons move from a low- To a high-risk area?
-
Williams CN. Does the incidence of IBD increase when persons move from a low- to a high-risk area? Inflamm Bowel Dis 2008;14(Suppl 2):S41-2.
-
(2008)
Inflamm Bowel Dis
, vol.14
, Issue.SUPPL. 2
-
-
Williams, C.N.1
-
20
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
DOI 10.1038/ng1089
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genet 2003;33 Suppl:245-54. (Pubitemid 36278835)
-
(2003)
Nature Genetics
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
21
-
-
68049084872
-
Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development
-
Waterland RA, Kellermayer R, Rached MT, et al. Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development. Hum Mol Genet 2009;18:3026-38.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3026-3038
-
-
Waterland, R.A.1
Kellermayer, R.2
Rached, M.T.3
-
22
-
-
78650584064
-
CpG methylation of half-CRE sequences creates C/EBPalpha binding sites that activate some tissue-specific genes
-
Rishi V, Bhattacharya P, Chatterjee R, et al. CpG methylation of half-CRE sequences creates C/EBPalpha binding sites that activate some tissue-specific genes. Proc Natl Acad Sci USA 2010;107:20311-6.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20311-20316
-
-
Rishi, V.1
Bhattacharya, P.2
Chatterjee, R.3
-
23
-
-
84867145980
-
On the presence and role of human gene-body DNA methylation
-
Jjingo D, Conley AB, Yi SV, Lunyak VV, Jordan IK. On the presence and role of human gene-body DNA methylation. Oncotarget 2012;3:462-74.
-
(2012)
Oncotarget
, vol.3
, pp. 462-474
-
-
Jjingo, D.1
Conley, A.B.2
Yi, S.V.3
Lunyak, V.V.4
Jordan, I.K.5
-
24
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992;69:915-26.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
25
-
-
35548941189
-
Epigenetic epidemiology of the developmental origins hypothesis
-
DOI 10.1146/annurev.nutr.27.061406.093705
-
Waterland RA, Michels KB. Epigenetic epidemiology of the developmental origins hypothesis. Annu Rev Nutr 2007;27:363-88. (Pubitemid 351373362)
-
(2007)
Annual Review of Nutrition
, vol.27
, pp. 363-388
-
-
Waterland, R.A.1
Michels, K.B.2
-
26
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S, et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 2011;473:398-402.
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
-
27
-
-
84864053192
-
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
-
Orr BA, Haffner MC, Nelson WG, Yegnasubramanian S, Eberhart CG. Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. PLoS ONE 2012;7:e41036.
-
(2012)
PLoS ONE
, vol.7
-
-
Orr, B.A.1
Haffner, M.C.2
Nelson, W.G.3
Yegnasubramanian, S.4
Eberhart, C.G.5
-
28
-
-
0036527775
-
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
-
Johnstone RW. Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer. Nat Rev Drug Discov 2002;1:287-99. (Pubitemid 37361445)
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, Issue.4
, pp. 287-299
-
-
Johnstone, R.W.1
-
29
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
DOI 10.1038/38444
-
Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 1997;389:251-60. (Pubitemid 27406632)
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
30
-
-
77949678340
-
Chromatin structure and the inheritance of epigenetic information
-
Margueron R, Reinberg D. Chromatin structure and the inheritance of epigenetic information. Nat Rev Genet 2010;11:285-96.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 285-296
-
-
Margueron, R.1
Reinberg, D.2
-
31
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S, et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 2011;146:1016-28.
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
-
32
-
-
79955473684
-
Operating on chromatin, a colorful language where context matters
-
Gardner KE, Allis CD, Strahl BD. Operating on chromatin, a colorful language where context matters. J Mol Biol 2011;409:36-46.
-
(2011)
J Mol Biol
, vol.409
, pp. 36-46
-
-
Gardner, K.E.1
Allis, C.D.2
Strahl, B.D.3
-
33
-
-
84860119507
-
Long non-coding RNAs: Versatile master regulators of gene expression and crucial players in cancer
-
Nie L, Wu HJ, Hsu JM, et al. Long non-coding RNAs: Versatile master regulators of gene expression and crucial players in cancer. Am J Transl Res 2012;4:127-50.
-
(2012)
Am J Transl Res
, vol.4
, pp. 127-150
-
-
Nie, L.1
Wu, H.J.2
Hsu, J.M.3
-
34
-
-
84861968721
-
Small non-coding RNAs mount a silent revolution in gene expression
-
Aalto AP, Pasquinelli AE. Small non-coding RNAs mount a silent revolution in gene expression. Curr Opin Cell Biol 2012;24:333-40.
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 333-340
-
-
Aalto, A.P.1
Pasquinelli, A.E.2
-
35
-
-
80053111156
-
On the minimization of fluctuations in the response times of autoregulatory gene networks
-
Murugan R, Kreiman G. On the minimization of fluctuations in the response times of autoregulatory gene networks. Biophys J 2011;101:1297-306.
-
(2011)
Biophys J
, vol.101
, pp. 1297-1306
-
-
Murugan, R.1
Kreiman, G.2
-
36
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
-
DOI 10.1073/pnas.91.21.9926
-
Moi P, Chan K, Asunis I, Cao A, Kan YW. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 1994;91:9926-30. (Pubitemid 24311921)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.21
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
37
-
-
80053978389
-
Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation
-
Khor TO, Huang Y, Wu TY, Shu L, Lee J, Kong AN. Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation. Biochem Pharmacol 2011;82:1073-8.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1073-1078
-
-
Khor, T.O.1
Huang, Y.2
Wu, T.Y.3
Shu, L.4
Lee, J.5
Kong, A.N.6
-
38
-
-
84862824580
-
Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage
-
Wang B, Zhu X, Kim Y, et al. Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage. Free Radic Biol Med 2012;52:928-36.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 928-936
-
-
Wang, B.1
Zhu, X.2
Kim, Y.3
-
39
-
-
84862494503
-
The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops
-
Papp D, Lenti K, Modos D, et al. The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops. FEBS Lett 2012;586:1795-802.
-
(2012)
FEBS Lett
, vol.586
, pp. 1795-1802
-
-
Papp, D.1
Lenti, K.2
Modos, D.3
-
40
-
-
84868267844
-
Recent advances in nutrition, genes and brain health
-
Dauncey MJ. Recent advances in nutrition, genes and brain health. Proc Nutr Soc 2012:1-11.
-
(2012)
Proc Nutr Soc
, pp. 1-11
-
-
Dauncey, M.J.1
-
41
-
-
84862909044
-
Next steps in cardiovascular disease genomic research - Sequencing, epigenetics, and transcriptomics
-
Schnabel RB, Baccarelli A, Lin H, Ellinor PT, Benjamin EJ. Next steps in cardiovascular disease genomic research - sequencing, epigenetics, and transcriptomics. Clin Chem 2012;58:113-26.
-
(2012)
Clin Chem
, vol.58
, pp. 113-126
-
-
Schnabel, R.B.1
Baccarelli, A.2
Lin, H.3
Ellinor, P.T.4
Benjamin, E.J.5
-
42
-
-
84863809559
-
Fundamental concepts of epigenetics for consideration in anesthesiology
-
Naguib M, Bie B, Ting AH. Fundamental concepts of epigenetics for consideration in anesthesiology. Curr Opin Anaesthesiol 2012;25:434-43.
-
(2012)
Curr Opin Anaesthesiol
, vol.25
, pp. 434-443
-
-
Naguib, M.1
Bie, B.2
Ting, A.H.3
-
43
-
-
84866367184
-
Epigenetics: Concepts and relevance to IBD pathogenesis
-
Scarpa M, Stylianou E. Epigenetics: Concepts and relevance to IBD pathogenesis. Inflamm Bowel Dis 2012;18:1982-96.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 1982-1996
-
-
Scarpa, M.1
Stylianou, E.2
-
44
-
-
80855144211
-
Absence of focally enhanced gastritis in macaques with idiopathic colitis
-
Sonnenberg A, Melton SD, Genta RM, Lewis AD. Absence of focally enhanced gastritis in macaques with idiopathic colitis. Inflamm Bowel Dis 2011;12:2456-61.
-
(2011)
Inflamm Bowel Dis
, vol.12
, pp. 2456-2461
-
-
Sonnenberg, A.1
Melton, S.D.2
Genta, R.M.3
Lewis, A.D.4
-
45
-
-
79951868908
-
Key questions to guide a better understanding of host-commensal microbiota interactions in intestinal inflammation
-
Sartor RB. Key questions to guide a better understanding of host-commensal microbiota interactions in intestinal inflammation. Mucosal Immunol 2011;4:127-32.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 127-132
-
-
Sartor, R.B.1
-
46
-
-
78649647805
-
Genetic drift. "Omics" as the filtering gateway between environment and phenotype: The inflammatory bowel diseases example
-
Kellermayer R. Genetic drift. "Omics" as the filtering gateway between environment and phenotype: The inflammatory bowel diseases example. Am J Med Genet A 2010;152A:3022-5.
-
(2010)
Am J Med Genet A
, vol.152 A
, pp. 3022-3025
-
-
Kellermayer, R.1
-
47
-
-
80051812841
-
The remarkable capacity for gut microbial and host interactions
-
Nagy-Szakal D, Kellermayer R. The remarkable capacity for gut microbial and host interactions. Gut Microbes 2011;2:178-82.
-
(2011)
Gut Microbes
, vol.2
, pp. 178-182
-
-
Nagy-Szakal, D.1
Kellermayer, R.2
-
48
-
-
78650352867
-
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa
-
Phila
-
Wallace K, Grau MV, Levine AJ, et al. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila) 2010;3:1552-64.
-
(2010)
Cancer Prev Res
, vol.3
, pp. 1552-1564
-
-
Wallace, K.1
Grau, M.V.2
Levine, A.J.3
-
49
-
-
78649653854
-
6-Thioguanine and S-methylthioguanine are mutagenic in human cells
-
Yuan B, O'Connor TR, Wang Y. 6-Thioguanine and S-methylthioguanine are mutagenic in human cells. ACS Chem Biol 2010;5:1021-7.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 1021-1027
-
-
Yuan, B.1
O'Connor, T.R.2
Wang, Y.3
-
50
-
-
59249107052
-
DNA methylation profiles in monozygotic and dizygotic twins
-
Kaminsky ZA, Tang T, Wang SC, et al. DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet 2009;41:240-5.
-
(2009)
Nat Genet
, vol.41
, pp. 240-245
-
-
Kaminsky, Z.A.1
Tang, T.2
Wang, S.C.3
-
51
-
-
80051539323
-
DNA methylation of colon mucosa in ulcerative colitis patients: Correlation with inflammatory status
-
Saito S, Kato J, Hiraoka S, et al. DNA methylation of colon mucosa in ulcerative colitis patients: Correlation with inflammatory status. Inflamm Bowel Dis 2011;9:1955-65.
-
(2011)
Inflamm Bowel Dis
, vol.9
, pp. 1955-1965
-
-
Saito, S.1
Kato, J.2
Hiraoka, S.3
-
52
-
-
79958119436
-
Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease
-
Lin Z, Hegarty JP, Cappel JA, et al. Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease. Clin Genet 2011;80:59-67.
-
(2011)
Clin Genet
, vol.80
, pp. 59-67
-
-
Lin, Z.1
Hegarty, J.P.2
Cappel, J.A.3
-
53
-
-
84859795659
-
Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway
-
Nimmo ER, Prendergast JG, Aldhous MC, et al. Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway. Inflamm Bowel Dis 2012;18:889-99.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 889-899
-
-
Nimmo, E.R.1
Prendergast, J.G.2
Aldhous, M.C.3
-
54
-
-
78650102072
-
Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens
-
Gonsky R, Deem RL, Landers CJ, et al. Distinct IFNG methylation in a subset of ulcerative colitis patients based on reactivity to microbial antigens. Inflamm Bowel Dis 2011;17:171-8.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 171-178
-
-
Gonsky, R.1
Deem, R.L.2
Landers, C.J.3
-
55
-
-
84869216522
-
Genome-wide peripheral blood leukocyte DNA methylation microarrays identified a single association with inflammatory bowel diseases
-
March 29 doi:10.1002/ibd.22956 (E-pub ahead of print)
-
Harris RA, Nagy-Szakal D, Pedersen N, et al. Genome-wide peripheral blood leukocyte DNA methylation microarrays identified a single association with inflammatory bowel diseases. Inflamm Bowel Dis 2012, March 29. doi:10.1002/ibd.22956 (E-pub ahead of print).
-
(2012)
Inflamm Bowel Dis
-
-
Harris, R.A.1
Nagy-Szakal, D.2
Pedersen, N.3
-
56
-
-
80054760346
-
STAT6 activation in ulcerative colitis: A new target for prevention of IL-13-induced colon epithelial cell dysfunction
-
Rosen MJ, Frey MR, Washington MK, et al. STAT6 activation in ulcerative colitis: A new target for prevention of IL-13-induced colon epithelial cell dysfunction. Inflamm Bowel Dis 2011;17:2224-34.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 2224-2234
-
-
Rosen, M.J.1
Frey, M.R.2
Washington, M.K.3
-
57
-
-
78650119948
-
Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease
-
Wu F, Guo NJ, Tian H, et al. Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease. Inflamm Bowel Dis 2011;17:241-50.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 241-250
-
-
Wu, F.1
Guo, N.J.2
Tian, H.3
-
58
-
-
84863242402
-
miR-200b is involved in intestinal fibrosis of Crohn's disease
-
Chen Y, Ge W, Xu L, et al. miR-200b is involved in intestinal fibrosis of Crohn's disease. Int J Mol Med 2012;29:601-6.
-
(2012)
Int J Mol Med
, vol.29
, pp. 601-606
-
-
Chen, Y.1
Ge, W.2
Xu, L.3
-
59
-
-
79959852640
-
Circulating MicroRNA is a biomarker of pediatric Crohn disease
-
Zahm AM, Thayu M, Hand NJ, Horner A, Leonard MB, Friedman JR. Circulating MicroRNA is a biomarker of pediatric Crohn disease. J Pediatr Gastroenterol Nutr 2011;53:26-33.
-
(2011)
J Pediatr Gastroenterol Nutr
, vol.53
, pp. 26-33
-
-
Zahm, A.M.1
Thayu, M.2
Hand, N.J.3
Horner, A.4
Leonard, M.B.5
Friedman, J.R.6
-
60
-
-
0019506454
-
The somatic replication of DNA methylation
-
Wigler M, Levy D, Perucho M. The somatic replication of DNA methylation. Cell 1981;24:33-40. (Pubitemid 11157127)
-
(1981)
Cell
, vol.24
, Issue.1
, pp. 33-40
-
-
Wigler, M.1
Levy, D.2
Perucho, M.3
-
61
-
-
79960148707
-
Timing is everything: The when and how of environmentally induced changes in the epigenome of animals
-
Faulk C, Dolinoy DC. Timing is everything: The when and how of environmentally induced changes in the epigenome of animals. Epigenetics 2011;6:791-7.
-
(2011)
Epigenetics
, vol.6
, pp. 791-797
-
-
Faulk, C.1
Dolinoy, D.C.2
-
62
-
-
82355190928
-
How can the Developmental Origins of Health and Disease (DOHaD) hypothesis contribute to improving health in developing countries?
-
Uauy R, Kain J, Corvalan C. How can the Developmental Origins of Health and Disease (DOHaD) hypothesis contribute to improving health in developing countries? Am J Clin Nutr 2011;94:1759S-64S.
-
(2011)
Am J Clin Nutr
, vol.94
-
-
Uauy, R.1
Kain, J.2
Corvalan, C.3
-
63
-
-
69349095789
-
Developmental origins of health and disease: Brief history of the approach and current focus on epigenetic mechanisms
-
Wadhwa PD, Buss C, Entringer S, Swanson JM. Developmental origins of health and disease: Brief history of the approach and current focus on epigenetic mechanisms. Semin Reprod Med 2009;27:358-68.
-
(2009)
Semin Reprod Med
, vol.27
, pp. 358-368
-
-
Wadhwa, P.D.1
Buss, C.2
Entringer, S.3
Swanson, J.M.4
-
64
-
-
79958813766
-
Air pollution: An environmental factor contributing to intestinal disease
-
Beamish LA, Osornio-Vargas AR, Wine E. Air pollution: An environmental factor contributing to intestinal disease. J Crohns Colitis 2011;5:279-86.
-
(2011)
J Crohns Colitis
, vol.5
, pp. 279-286
-
-
Beamish, L.A.1
Osornio-Vargas, A.R.2
Wine, E.3
-
65
-
-
59849129867
-
Crohn's disease and early exposure to domestic refrigeration
-
Malekzadeh F, Alberti C, Nouraei M, et al. Crohn's disease and early exposure to domestic refrigeration. PLoS One 2009;4:e4288.
-
(2009)
PLoS One
, vol.4
-
-
Malekzadeh, F.1
Alberti, C.2
Nouraei, M.3
-
66
-
-
0028217167
-
Inflammatory bowel disease and domestic hygiene in infancy
-
Gent AE, Hellier MD, Grace RH, Swarbrick ET, Coggon D. Inflammatory bowel disease and domestic hygiene in infancy. Lancet 1994;343:766-7.
-
(1994)
Lancet
, vol.343
, pp. 766-767
-
-
Gent, A.E.1
Hellier, M.D.2
Grace, R.H.3
Swarbrick, E.T.4
Coggon, D.5
-
67
-
-
84856443297
-
Helminth-host immunological interactions: Prevention and control of immune-mediated diseases
-
Elliott DE, Weinstock JV. Helminth-host immunological interactions: Prevention and control of immune-mediated diseases. Ann N Y Acad Sci 2012;1247:83-96.
-
(2012)
Ann N y Acad Sci
, vol.1247
, pp. 83-96
-
-
Elliott, D.E.1
Weinstock, J.V.2
-
68
-
-
79953773560
-
Dietary intake and risk of developing inflammatory bowel disease: A systematic review of the literature
-
Hou JK, Abraham B, El-Serag H. Dietary intake and risk of developing inflammatory bowel disease: A systematic review of the literature. Am J Gastroenterol 2011;106:563-73.
-
(2011)
Am J Gastroenterol
, vol.106
, pp. 563-573
-
-
Hou, J.K.1
Abraham, B.2
El-Serag, H.3
-
69
-
-
72549092109
-
Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: A nested case-control study within a European prospective cohort study
-
Tjonneland A, Overvad K, Bergmann MM, et al. Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: A nested case-control study within a European prospective cohort study. Gut 2009;58:1606-11.
-
(2009)
Gut
, vol.58
, pp. 1606-1611
-
-
Tjonneland, A.1
Overvad, K.2
Bergmann, M.M.3
-
70
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
Petronis A. Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 2010;465:721-7.
-
(2010)
Nature
, vol.465
, pp. 721-727
-
-
Petronis, A.1
-
71
-
-
0032820842
-
The effects of migration on ulcerative colitis: A three-year prospective study among Europeans and first- and second-generation South Asians in Leicester (1991-1994)
-
DOI 10.1016/S0002-9270(99)00494-3, PII S0002927099004943
-
Carr I, Mayberry JF. The effects of migration on ulcerative colitis: A three-year prospective study among Europeans and first- and second- generation South Asians in Leicester (1991-1994). Am J Gastroenterol 1999;94:2918-22. (Pubitemid 29482758)
-
(1999)
American Journal of Gastroenterology
, vol.94
, Issue.10
, pp. 2918-2922
-
-
Carr, I.1
Mayberry, J.F.2
-
72
-
-
79960276599
-
Risk of inflammatory bowel disease in first- And second-generation immigrants in Sweden: A nationwide follow-up study
-
Li X, Sundquist J, Hemminki K, Sundquist K. Risk of inflammatory bowel disease in first- and second-generation immigrants in Sweden: A nationwide follow-up study. Inflamm Bowel Dis 2011;17:1784-91.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1784-1791
-
-
Li, X.1
Sundquist, J.2
Hemminki, K.3
Sundquist, K.4
-
73
-
-
34247891473
-
Inflammatory bowel disease in the South Asian pediatric population of British Columbia
-
DOI 10.1111/j.1572-0241.2007.01124.x
-
Pinsk V, Lemberg DA, Grewal K, Barker CC, Schreiber RA, Jacobson K. Inflammatory bowel disease in the South Asian pediatric population of British Columbia. Am J Gastroenterol 2007;102:1077-83. (Pubitemid 46698231)
-
(2007)
American Journal of Gastroenterology
, vol.102
, Issue.5
, pp. 1077-1083
-
-
Pinsk, V.1
Lemberg, D.A.2
Grewal, K.3
Barker, C.C.4
Schreiber, R.A.5
Jacobson, K.6
-
74
-
-
82255186408
-
Emigration to western industrialized countries: A risk factor for developing inflammatory bowel disease
-
Barreiro-de Acosta M, Alvarez Castro A, Souto R, Iglesias M, Lorenzo A, Dominguez-Munoz JE. Emigration to western industrialized countries: A risk factor for developing inflammatory bowel disease. J Crohns Colitis 2011;5:566-9.
-
(2011)
J Crohns Colitis
, vol.5
, pp. 566-569
-
-
Barreiro-de Acosta, M.1
Alvarez Castro, A.2
Souto, R.3
Iglesias, M.4
Lorenzo, A.5
Dominguez-Munoz, J.E.6
-
75
-
-
84864258739
-
The age of gene discovery in very early onset inflammatory bowel disease
-
Muise AM, Snapper SB, Kugathasan S. The age of gene discovery in very early onset inflammatory bowel disease. Gastroenterology 2012;143:285-8.
-
(2012)
Gastroenterology
, vol.143
, pp. 285-288
-
-
Muise, A.M.1
Snapper, S.B.2
Kugathasan, S.3
-
76
-
-
0036808221
-
Monozygotic twins with a severe form of Alagille syndrome and phenotypic discordance
-
DOI 10.1002/ajmg.10610
-
Kamath BM, Krantz ID, Spinner NB, Heubi JE, Piccoli DA. Monozygotic twins with a severe form of Alagille syndrome and phenotypic discordance. Am J Med Genet 2002;112:194-7. (Pubitemid 35332186)
-
(2002)
American Journal of Medical Genetics
, vol.112
, Issue.2
, pp. 194-197
-
-
Kamath, B.M.1
Krantz, I.D.2
Spinner, N.B.3
Heubi, J.E.4
Piccoli, D.A.5
-
77
-
-
34249899923
-
Physiologic noise obscures genotype-phenotype correlations [2]
-
DOI 10.1002/ajmg.a.31825
-
Kellermayer R. Genetic drift. Physiologic noise obscures genotype-phenotype correlations. Am J Med Genet A 2007;143A:1306-7. (Pubitemid 46870095)
-
(2007)
American Journal of Medical Genetics, Part A
, vol.143
, Issue.12
, pp. 1306-1307
-
-
Kellermayer, R.1
-
78
-
-
0036322831
-
Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring
-
Cooney CA, Dave AA, Wolff GL. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr 2002;132:2393S-400S. (Pubitemid 34848114)
-
(2002)
Journal of Nutrition
, vol.132
, Issue.8 SUPPL.
-
-
Cooney, C.A.1
Dave, A.A.2
Wolff, G.L.3
-
79
-
-
78650688321
-
Season of conception in rural Gambia affects DNA methylation at putative human metastable epialleles
-
Waterland RA, Kellermayer R, Laritsky E, et al. Season of conception in rural Gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet 2010;6:e1001252.
-
(2010)
PLoS Genet
, vol.6
-
-
Waterland, R.A.1
Kellermayer, R.2
Laritsky, E.3
-
80
-
-
84859222932
-
Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: A study of a unique resource in the Gambia
-
Khulan B, Cooper WN, Skinner BM, et al. Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: A study of a unique resource in the Gambia. Hum Mol Genet 2012;21:2086-101.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2086-2101
-
-
Khulan, B.1
Cooper, W.N.2
Skinner, B.M.3
-
81
-
-
80051812841
-
The remarkable capacity for gut microbial and host interactions
-
Nagy-Szakal D, Kellermayer R. The remarkable capacity for gut microbial and host interactions. Gut Microbes 2011;2:178-82
-
(2011)
Gut Microbes
, vol.2
, pp. 178-182
-
-
Nagy-Szakal, D.1
Kellermayer, R.2
-
82
-
-
77953597976
-
Epigenetic maturation in colonic mucosa continues beyond infancy in mice
-
Kellermayer R, Balasa A, Zhang W, et al. Epigenetic maturation in colonic mucosa continues beyond infancy in mice. Hum Mol Genet 2010;19:2168-76.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2168-2176
-
-
Kellermayer, R.1
Balasa, A.2
Zhang, W.3
-
83
-
-
79958025266
-
An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling
-
Kominsky DJ, Keely S, MacManus CF, et al. An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. J Immunol 2011;186:6505-14.
-
(2011)
J Immunol
, vol.186
, pp. 6505-6514
-
-
Kominsky, D.J.1
Keely, S.2
MacManus, C.F.3
-
84
-
-
79954519615
-
Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes
-
Schaible TD, Harris RA, Dowd SE, Smith CW, Kellermayer R. Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes. Hum Mol Genet 2011;20:1687-96.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1687-1696
-
-
Schaible, T.D.1
Harris, R.A.2
Dowd, S.E.3
Smith, C.W.4
Kellermayer, R.5
-
85
-
-
85046981892
-
Maternal micronutrients can modify colonic mucosal microbiota maturation in murine offspring
-
Nagy-Szakal D, Ross MC, Dowd SE, et al. Maternal micronutrients can modify colonic mucosal microbiota maturation in murine offspring. Gut Microbes 2012;3:426-33.
-
(2012)
Gut Microbes
, vol.3
, pp. 426-433
-
-
Nagy-Szakal, D.1
Ross, M.C.2
Dowd, S.E.3
-
86
-
-
79751519983
-
Maternal obesity induces sustained inflammation in both fetal and offspring large intestine of sheep
-
Yan X, Huang Y, Wang H, et al. Maternal obesity induces sustained inflammation in both fetal and offspring large intestine of sheep. Inflamm Bowel Dis 2011;17:1513-22.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1513-1522
-
-
Yan, X.1
Huang, Y.2
Wang, H.3
-
87
-
-
78649735738
-
Perinatal lipid nutrition alters early intestinal development and programs the response to experimental colitis in young adult rats
-
Innis SM, Dai C, Wu X, Buchan AM, Jacobson K. Perinatal lipid nutrition alters early intestinal development and programs the response to experimental colitis in young adult rats. Am J Physiol Gastrointest Liver Physiol 2010;299:G1376-85.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.299
-
-
Innis, S.M.1
Dai, C.2
Wu, X.3
Buchan, A.M.4
Jacobson, K.5
-
88
-
-
44249087835
-
Early life stress enhances the vulnerability to chronic psychosocial stress and experimental colitis in adult mice
-
DOI 10.1210/en.2007-1469
-
Veenema AH, Reber SO, Selch S, Obermeier F, Neumann ID. Early life stress enhances the vulnerability to chronic psychosocial stress and experimental colitis in adult mice. Endocrinology 2008;149:2727-36. (Pubitemid 351724511)
-
(2008)
Endocrinology
, vol.149
, Issue.6
, pp. 2727-2736
-
-
Veenema, A.H.1
Reber, S.O.2
Selch, S.3
Obermeier, F.4
Neumann, I.D.5
-
89
-
-
71549146864
-
Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
-
Mulder IE, Schmidt B, Stokes CR, et al. Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces. BMC Biol 2009;7:79.
-
(2009)
BMC Biol
, vol.7
, pp. 79
-
-
Mulder, I.E.1
Schmidt, B.2
Stokes, C.R.3
-
90
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
Atarashi K, Tanoue T, Shima T, et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011;331:337-41.
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
-
91
-
-
80053922802
-
Epigenetic control of the host gene by commensal bacteria in large intestinal epithelial cells
-
Takahashi K, Sugi Y, Nakano K, et al. Epigenetic control of the host gene by commensal bacteria in large intestinal epithelial cells. J Biol Chem 2011;286:35755-62.
-
(2011)
J Biol Chem
, vol.286
, pp. 35755-35762
-
-
Takahashi, K.1
Sugi, Y.2
Nakano, K.3
-
92
-
-
79959437681
-
Epigenetic regulation of human beta-defensin 2 and CC chemokine ligand 20 expression in gingival epithelial cells in response to oral bacteria
-
Yin L, Chung WO. Epigenetic regulation of human beta-defensin 2 and CC chemokine ligand 20 expression in gingival epithelial cells in response to oral bacteria. Mucosal Immunol 2011;4:409-19.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 409-419
-
-
Yin, L.1
Chung, W.O.2
-
93
-
-
77951666511
-
CpG methylation and reduced expression of O6-methylguanine DNA methyltransferase is associated with Helicobacter pylori infection
-
Sepulveda AR, Yao Y, Yan W, et al. CpG methylation and reduced expression of O6-methylguanine DNA methyltransferase is associated with Helicobacter pylori infection. Gastroenterology 2010;138:1836-44.
-
(2010)
Gastroenterology
, vol.138
, pp. 1836-1844
-
-
Sepulveda, A.R.1
Yao, Y.2
Yan, W.3
-
94
-
-
84860216630
-
Microbial exposure during early life has persistent effects on natural killer T cell function
-
Olszak T, An D, Zeissig S, et al. Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012;336:489-93.
-
(2012)
Science
, vol.336
, pp. 489-493
-
-
Olszak, T.1
An, D.2
Zeissig, S.3
|